Annotation (Toggle Detail/Summary View) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology Annotations
Gene Ontology AnnotationsBiological Process Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | embryonic placenta development | | ISO | RGD:1620859 | 1624291 | MGI:MGI:4456438 | RGD | MGI:MGI:4453264 PMID:20178780 | embryonic placenta development | | IEA | Ensembl:ENSMUSP00000054834 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | Golgi organization | | ISO | RGD:735876 | 1624291 | PMID:17693410 | RGD | PMID:17693410 | Golgi organization | | ISS | UniProtKB:Q15363 | 1600115 | GO_REF:0000024 | UniProtKB | GO_REF:0000024 | heart looping | | ISO | RGD:1620859 | 1624291 | MGI:MGI:4456438|MGI:MGI:4343479 | RGD | MGI:MGI:4453264 PMID:20178780 | heart looping | | IEA | Ensembl:ENSMUSP00000054834 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | in utero embryonic development | | ISO | RGD:1620859 | 1624291 | MGI:MGI:4456438|MGI:MGI:4343479 | RGD | MGI:MGI:4453264 PMID:20178780 | intracellular protein transport | | ISO | RGD:735876 | 1624291 | PMID:20427317 | RGD | PMID:20427317 | intracellular protein transport | | NAS | | 68840 | PMID:8663407 | HGNC | | maternal placenta development | | IEA | Ensembl:ENSMUSP00000054834 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | multicellular organism growth | | ISO | RGD:1620859 | 1624291 | MGI:MGI:4343479|MGI:MGI:4456438 | RGD | MGI:MGI:4453264 PMID:20178780 | multicellular organism growth | | IEA | Ensembl:ENSMUSP00000054834 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | negative regulation of GTPase activity | | ISO | RGD:735876 | 1624291 | PMID:10761932 | RGD | PMID:10761932 | negative regulation of GTPase activity | | ISS | UniProtKB:Q15363 | 1600115 | GO_REF:0000024 | UniProtKB | GO_REF:0000024 | neural tube closure | | ISO | RGD:1620859 | 1624291 | MGI:MGI:4456438 | RGD | MGI:MGI:4453264 PMID:20178780 | neural tube closure | | IEA | Ensembl:ENSMUSP00000054834 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | positive regulation of gene expression | | ISO | RGD:1620859 | 1624291 | MGI:MGI:4456438 | RGD | MGI:MGI:4453264 PMID:20178780 | positive regulation of gene expression | | IEA | Ensembl:ENSMUSP00000054834 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | post-anal tail morphogenesis | | ISO | RGD:1620859 | 1624291 | MGI:MGI:4456438|MGI:MGI:4343479 | RGD | MGI:MGI:4453264 PMID:20178780 | post-anal tail morphogenesis | | IEA | Ensembl:ENSMUSP00000054834 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | protein targeting to plasma membrane | | ISO | RGD:735876 | 1624291 | PMID:20361938 | RGD | PMID:20361938 | protein targeting to plasma membrane | | ISS | UniProtKB:Q15363 | 1600115 | GO_REF:0000024 | UniProtKB | GO_REF:0000024 | somite rostral/caudal axis specification | | ISO | RGD:1620859 | 1624291 | MGI:MGI:4456438 | RGD | MGI:MGI:4453264 PMID:20178780 | somite rostral/caudal axis specification | | IEA | Ensembl:ENSMUSP00000054834 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | somitogenesis | | ISO | RGD:1620859 | 1624291 | MGI:MGI:4456438 | RGD | MGI:MGI:4453264 PMID:20178780 | vesicle targeting | | NAS | | 68840 | PMID:8663407 | HGNC | | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene-Chemical Interaction Annotations
|
|
Gene Ontology Annotations
|
|
|
References - curated| 1. |
Blum R, etal., J Biol Chem 1996 Jul 19;271(29):17183-9. |
| 2. |
NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 3. |
RGD automated data pipeline |
| 4. |
RGD automated import pipeline for gene-chemical interactions |
| 5. |
Tentative Sequence Data IDs. TIGR Gene Index, Rat Data |
References - uncurated
RGD Disease Portals
Comparative Map Data| Tmed2 (Rattus norvegicus) |
|
||||||||||||||||||||||||||||||||||||||||
| TMED2 (Homo sapiens) |
|
||||||||||||||||||||||||||||||||||||||||
| Tmed2 (Mus musculus) |
|
Position Markers| RH125644 |
|
|||||||||||||||||||||||||
| RH124557 |
|
|||||||||||||||||||||||||
| Tmed2 |
|
|||||||||||||||||||||||||
| Tmed2 |
|
QTLs in Region (RGSC Genome Assembly v3.4)| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
Nucleotide Sequences| Nucleotide RefSeqs | NM_031722 | (Get FASTA) | Search GEO for Microarray Profiles |
| GenBank Nucleotide | AABR06071937 | (Get FASTA) | Search GEO for Microarray Profiles |
| AAHX01072376 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BC062036 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CH473973 | (Get FASTA) | Search GEO for Microarray Profiles | |
| FQ229555 | (Get FASTA) | Search GEO for Microarray Profiles | |
| X92097 | (Get FASTA) | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | NM_031722 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Protein Acc Id: | NP_113910 | ||||||||||||||||||||
| Peptide Label: | precursor | ||||||||||||||||||||
| Position: |
|
Protein Sequences| Protein RefSeqs | NP_113910 | (Get FASTA) |
| GenBank Protein | AAH62036 | (Get FASTA) |
| CAA63068 | (Get FASTA) | |
| EDM13579 | (Get FASTA) | |
| Q63524 | (Get FASTA) |
Strain Sequence Variants
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSRNOG00000001053 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Protein | ENSRNOP00000001397 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Transcript | ENSRNOT00000001397 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Entrez Gene | 65165 | ENTREZGENE |
| Germonline | ENSRNOG00000001053 | UniProtKB/Swiss-Prot |
| HomoloGene Group ID | 55991 | ENTREZGENE |
| IMAGE_CLONE | IMAGE:5623841 | IMAGE-MGC_LOAD |
| InterPro | GOLD | UniProtKB/Swiss-Prot |
| IPI | IPI00210008 | UniProtKB/Swiss-Prot |
| KEGG Report | rno:65165 | ENTREZGENE, UniProtKB/Swiss-Prot |
| MGC_CLONE | MGC:72390 | IMAGE-MGC_LOAD |
| Pfam | EMP24_GP25L | UniProtKB/Swiss-Prot |
| PROSITE | GOLD | UniProtKB/Swiss-Prot |
| Superfamily-SCOP | GOLD | UniProtKB/Swiss-Prot |
| TIGR | TC206186 | |
| UniGene | Rn.1022 | ENTREZGENE |
| UniProt | TMED2_RAT | UniProtKB/Swiss-Prot |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2006-03-30 | Tmed2 | transmembrane emp24 domain trafficking protein 2 | Rnp24 | coated vesicle membrane protein | Symbol and Name updated | 10779 | APPROVED |
| 2002-06-10 | Rnp24 | coated vesicle membrane protein | Name updated | 1488 | APPROVED |
RGD Curation Notes| Note Type | Note | Reference |
|---|
| More on Tmed2 | |
![]() |
Entrez Gene |
![]() |
Ensembl Gene |
![]() | Genome Browser |
![]() |
NCBI Map Viewer |
![]() |
Vista |
![]() |
Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 69243 |
| Created: | 2001-11-14 |
| Species: | Rattus norvegicus |
| Last Modified: | 2013-04-16 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.




