Marchf1 (membrane associated ring-CH-type finger 1) - Rat Genome Database

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Gene: Marchf1 (membrane associated ring-CH-type finger 1) Rattus norvegicus
Analyze
Symbol: Marchf1
Name: membrane associated ring-CH-type finger 1
RGD ID: 1305148
Description: Predicted to enable MHC protein binding activity and ubiquitin protein ligase activity. Predicted to be involved in antigen processing and presentation of peptide antigen via MHC class II; immune response; and protein polyubiquitination. Predicted to be located in several cellular components, including endoplasmic reticulum membrane; lysosomal membrane; and trans-Golgi network membrane. Predicted to be active in early endosome membrane; late endosome membrane; and lysosome. Orthologous to human MARCHF1 (membrane associated ring-CH-type finger 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase MARCH1; E3 ubiquitin-protein ligase MARCH1-like; E3 ubiquitin-protein ligase MARCHF1; LOC100910061; LOC361135; March1; membrane-associated ring finger (C3HC4) 1; membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase; RGD1305148; similar to hypothetical protein FLJ20668
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81628,022,159 - 28,880,872 (-)NCBIGRCr8
mRatBN7.21623,255,551 - 24,114,290 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1623,258,799 - 24,114,277 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1626,618,960 - 27,482,348 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01630,053,672 - 30,917,036 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01625,992,293 - 26,875,346 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01624,998,709 - 25,856,327 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1625,001,666 - 25,192,675 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01624,882,375 - 25,407,999 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41624,971,361 - 25,496,590 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11624,971,358 - 25,055,466 (-)NCBI
Celera1623,375,326 - 23,888,905 (-)NCBICelera
Cytogenetic Map16p14-p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14722266   PMID:17255932   PMID:18305173   PMID:18389477   PMID:19117940   PMID:19880452   PMID:19917682   PMID:27577745  


Genomics

Comparative Map Data
Marchf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81628,022,159 - 28,880,872 (-)NCBIGRCr8
mRatBN7.21623,255,551 - 24,114,290 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1623,258,799 - 24,114,277 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1626,618,960 - 27,482,348 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01630,053,672 - 30,917,036 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01625,992,293 - 26,875,346 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01624,998,709 - 25,856,327 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1625,001,666 - 25,192,675 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01624,882,375 - 25,407,999 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41624,971,361 - 25,496,590 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11624,971,358 - 25,055,466 (-)NCBI
Celera1623,375,326 - 23,888,905 (-)NCBICelera
Cytogenetic Map16p14-p13NCBI
MARCHF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384163,524,298 - 164,384,019 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4163,524,298 - 164,384,050 (-)EnsemblGRCh38hg38GRCh38
GRCh374164,445,450 - 165,305,171 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364164,668,499 - 164,754,226 (-)NCBINCBI36Build 36hg18NCBI36
Build 344164,806,653 - 164,892,381NCBI
Celera4161,777,720 - 162,636,895 (-)NCBICelera
Cytogenetic Map4q32.2-q32.3NCBI
HuRef4160,199,325 - 161,058,221 (-)NCBIHuRef
CHM1_14164,421,900 - 165,280,873 (-)NCBICHM1_1
T2T-CHM13v2.04166,872,170 - 167,731,735 (-)NCBIT2T-CHM13v2.0
Marchf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39866,070,558 - 66,925,761 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl866,070,552 - 66,924,289 (+)EnsemblGRCm39 Ensembl
GRCm38865,618,009 - 66,472,841 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl865,617,900 - 66,471,637 (+)EnsemblGRCm38mm10GRCm38
MGSCv37868,141,939 - 68,995,536 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36868,547,514 - 69,399,416 (+)NCBIMGSCv36mm8
Celera868,174,462 - 69,027,711 (+)NCBICelera
Cytogenetic Map8B3.1NCBI
cM Map833.06NCBI
Marchf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540341,060,246 - 41,484,734 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540341,187,039 - 41,484,734 (+)NCBIChiLan1.0ChiLan1.0
MARCHF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23161,340,439 - 162,192,916 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14161,702,902 - 162,551,136 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04155,791,599 - 156,639,456 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14167,579,850 - 168,692,736 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4167,583,874 - 168,153,648 (-)Ensemblpanpan1.1panPan2
MARCHF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11559,753,597 - 60,279,692 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1559,753,216 - 60,036,060 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1560,118,313 - 60,912,318 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01560,512,737 - 61,307,283 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1560,513,004 - 60,795,213 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11559,745,776 - 60,561,370 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01559,837,018 - 60,638,108 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01560,206,169 - 61,004,664 (-)NCBIUU_Cfam_GSD_1.0
Marchf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494316,472,621 - 17,186,316 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365551,610,268 - 2,097,985 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365551,810,896 - 2,097,870 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MARCHF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl852,375,514 - 52,951,033 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1852,375,510 - 52,951,031 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2855,502,841 - 55,523,454 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MARCHF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17109,978,620 - 110,783,623 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7109,979,056 - 110,063,661 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603789,799,273 - 90,615,833 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Marchf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475812,878,810 - 13,319,814 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475812,528,242 - 13,321,851 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Marchf1
5520 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:146
Count of miRNA genes:112
Interacting mature miRNAs:122
Transcripts:ENSRNOT00000032289
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126727669Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126727669Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)161900443575226532Rat
2302057Pia29Pristane induced arthritis QTL 293.60.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)162173597566735975Rat

Markers in Region
D16Got26  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21623,688,200 - 23,688,376 (+)MAPPERmRatBN7.2
Rnor_6.01625,431,274 - 25,431,449NCBIRnor6.0
Rnor_5.01625,314,487 - 25,314,662UniSTSRnor5.0
RGSC_v3.41625,403,389 - 25,403,562RGDRGSC3.4
RGSC_v3.41625,403,387 - 25,403,562UniSTSRGSC3.4
RGSC_v3.11625,403,387 - 25,403,560RGD
Celera1623,795,727 - 23,795,902UniSTS
RH 3.4 Map16286.9UniSTS
RH 3.4 Map16286.9RGD
RH 2.0 Map16329.9RGD
Cytogenetic Map16p14-p13UniSTS
RH144480  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21623,610,577 - 23,610,709 (+)MAPPERmRatBN7.2
Rnor_6.01625,353,878 - 25,354,009NCBIRnor6.0
Rnor_5.01625,237,091 - 25,237,222UniSTSRnor5.0
RGSC_v3.41625,324,990 - 25,325,121UniSTSRGSC3.4
Celera1623,718,102 - 23,718,233UniSTS
RH 3.4 Map16285.3UniSTS
Cytogenetic Map16p14-p13UniSTS
BI301985  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21623,398,620 - 23,398,812 (+)MAPPERmRatBN7.2
Rnor_6.01625,140,824 - 25,141,015NCBIRnor6.0
Rnor_5.01625,024,490 - 25,024,681UniSTSRnor5.0
RGSC_v3.41625,110,842 - 25,111,033UniSTSRGSC3.4
Celera1623,513,636 - 23,513,827UniSTS
RH 3.4 Map16290.3UniSTS
Cytogenetic Map16p14-p13UniSTS
RH138482  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21623,257,973 - 23,258,120 (+)MAPPERmRatBN7.2
Rnor_6.01626,077,239 - 26,077,385NCBIRnor6.0
Rnor_6.01624,999,993 - 25,000,139NCBIRnor6.0
Rnor_5.01625,962,945 - 25,963,091UniSTSRnor5.0
Rnor_5.01624,883,659 - 24,883,805UniSTSRnor5.0
RGSC_v3.41624,969,688 - 24,969,834UniSTSRGSC3.4
Celera1623,373,653 - 23,373,799UniSTS
RH 3.4 Map16281.2UniSTS
Cytogenetic Map16p14-p13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 1 12 36 1
Low 17 34 19 7 19 4 4 32 10 8 10 4
Below cutoff 1 22 18 18 18 4 7 2 17 23 4

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001135838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008771133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008771134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000032289   ⟹   ENSRNOP00000038896
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1623,258,799 - 23,781,405 (-)Ensembl
Rnor_6.0 Ensembl1625,001,666 - 25,192,675 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000082578   ⟹   ENSRNOP00000096247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1623,258,799 - 24,114,277 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110592   ⟹   ENSRNOP00000092175
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1623,258,799 - 24,114,277 (-)Ensembl
RefSeq Acc Id: NM_001135838   ⟹   NP_001129310
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81628,022,159 - 28,880,839 (-)NCBI
mRatBN7.21623,255,551 - 24,114,253 (-)NCBI
Rnor_6.01625,001,666 - 25,524,786 (-)NCBI
Rnor_5.01624,882,375 - 25,407,999 (-)NCBI
RGSC_v3.41624,971,361 - 25,496,590 (-)RGD
Celera1623,375,326 - 23,888,905 (-)RGD
Sequence:
RefSeq Acc Id: NM_001401505   ⟹   NP_001388434
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81628,022,159 - 28,880,839 (-)NCBI
mRatBN7.21623,255,551 - 24,114,253 (-)NCBI
RefSeq Acc Id: XM_008771134   ⟹   XP_008769356
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81628,022,159 - 28,880,857 (-)NCBI
mRatBN7.21623,255,554 - 24,114,274 (-)NCBI
Rnor_6.01624,998,709 - 25,378,795 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600175   ⟹   XP_017455664
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81628,022,159 - 28,548,043 (-)NCBI
mRatBN7.21623,255,554 - 23,781,400 (-)NCBI
Rnor_6.01624,998,709 - 25,378,797 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600176   ⟹   XP_017455665
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81628,022,159 - 28,880,872 (-)NCBI
mRatBN7.21623,255,554 - 24,114,290 (-)NCBI
Rnor_6.01624,998,709 - 25,378,800 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039094632   ⟹   XP_038950560
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81628,022,159 - 28,880,868 (-)NCBI
mRatBN7.21623,255,554 - 24,114,286 (-)NCBI
RefSeq Acc Id: XM_039094633   ⟹   XP_038950561
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81628,022,159 - 28,880,351 (-)NCBI
mRatBN7.21623,255,554 - 24,113,537 (-)NCBI
RefSeq Acc Id: XM_039094634   ⟹   XP_038950562
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81628,022,159 - 28,880,868 (-)NCBI
mRatBN7.21623,255,554 - 24,114,286 (-)NCBI
RefSeq Acc Id: XM_039094635   ⟹   XP_038950563
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81628,022,159 - 28,880,853 (-)NCBI
mRatBN7.21623,255,554 - 24,114,270 (-)NCBI
RefSeq Acc Id: XM_063275512   ⟹   XP_063131582
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81628,022,159 - 28,880,577 (-)NCBI
RefSeq Acc Id: XM_063275513   ⟹   XP_063131583
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81628,023,292 - 28,110,972 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001129310   ⟸   NM_001135838
- Peptide Label: isoform 2
- UniProtKB: D4A6K8 (UniProtKB/TrEMBL),   A6KFM4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008769356   ⟸   XM_008771134
- Peptide Label: isoform X5
- UniProtKB: A6KFM4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017455665   ⟸   XM_017600176
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017455664   ⟸   XM_017600175
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AH31 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000038896   ⟸   ENSRNOT00000032289
RefSeq Acc Id: XP_038950560   ⟸   XM_039094632
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AH31 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038950562   ⟸   XM_039094634
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038950563   ⟸   XM_039094635
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AQF1 (UniProtKB/TrEMBL),   A6KFM4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038950561   ⟸   XM_039094633
- Peptide Label: isoform X3
RefSeq Acc Id: ENSRNOP00000092175   ⟸   ENSRNOT00000110592
RefSeq Acc Id: ENSRNOP00000096247   ⟸   ENSRNOT00000082578
RefSeq Acc Id: NP_001388434   ⟸   NM_001401505
- Peptide Label: isoform 1
RefSeq Acc Id: XP_063131582   ⟸   XM_063275512
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063131583   ⟸   XM_063275513
- Peptide Label: isoform X6
Protein Domains
RING-CH-type   RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A6K8-F1-model_v2 AlphaFold D4A6K8 1-254 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305148 AgrOrtholog
BioCyc Gene G2FUF-11656 BioCyc
Ensembl Genes ENSRNOG00000026310 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000032289 ENTREZGENE
  ENSRNOT00000032289.4 UniProtKB/TrEMBL
  ENSRNOT00000082578.2 UniProtKB/TrEMBL
  ENSRNOT00000110592.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro Znf_RING UniProtKB/TrEMBL
  Znf_RING-CH UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report rno:361135 UniProtKB/TrEMBL
NCBI Gene 361135 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE MARCHF1 UniProtKB/TrEMBL
  LD02310P UniProtKB/TrEMBL
Pfam RINGv UniProtKB/TrEMBL
PhenoGen Marchf1 PhenoGen
PROSITE ZF_RING_2 UniProtKB/TrEMBL
  ZF_RING_CH UniProtKB/TrEMBL
RatGTEx ENSRNOG00000026310 RatGTEx
SMART RINGv UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt A0A8I6AH31 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AQF1 ENTREZGENE, UniProtKB/TrEMBL
  A6KFM4 ENTREZGENE, UniProtKB/TrEMBL
  D4A6K8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Marchf1  membrane associated ring-CH-type finger 1  LOC100910061  E3 ubiquitin-protein ligase MARCH1-like  Data merged from RGD:6500479 737654 PROVISIONAL
2019-08-08 Marchf1  membrane associated ring-CH-type finger 1  March1  membrane associated ring-CH-type finger 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-12-02 March1  membrane associated ring-CH-type finger 1  March1  membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-05 March1  membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase  March1  membrane-associated ring finger (C3HC4) 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100910061  E3 ubiquitin-protein ligase MARCH1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 March1  membrane-associated ring finger (C3HC4) 1   March1_predicted  membrane-associated ring finger (C3HC4) 1 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 March1_predicted  membrane-associated ring finger (C3HC4) 1 (predicted)  RGD1305148_predicted  similar to hypothetical protein FLJ20668 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1305148_predicted  similar to hypothetical protein FLJ20668 (predicted)  LOC361135_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC361135_predicted  similar to hypothetical protein FLJ20668 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL