Gene: Chrna1 (cholinergic receptor, nicotinic, alpha 1 (muscle)) Rattus norvegicus
Symbol: Chrna1
Name: cholinergic receptor, nicotinic, alpha 1 (muscle)
Description: ENCODES a protein that exhibits acetylcholine-activated cation-selective channel activity; acetylcholine binding (ortholog); acetylcholine receptor activity (ortholog); INVOLVED IN cation transmembrane transport; cation transport; skeletal muscle contraction; PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; ASSOCIATED WITH MULTIPLE PTERYGIUM SYNDROME, LETHAL TYPE (ortholog); Myasthenia Gravis, Autoimmune, Experimental (ortholog); Myasthenic Syndrome, Congenital, Fast-Channel (ortholog); FOUND IN acetylcholine-gated channel complex; cell surface (ortholog); membrane (ortholog); INTERACTS WITH acetylcholine; ammonium chloride; bisphenol A
Type: protein-coding
Also known as: acetylcholine receptor subunit alpha; cholinergic receptor nicotinic alpha polypeptide 1; cholinergic receptor nicotinic alpha polypeptide 1 (muscle); cholinergic receptor, nicotinic, alpha polypeptide 1; cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.0360,445,657 - 60,460,724-NCBI
Rat Cytogenetic Map3q23 NCBI
RGSC Genome Assembly v5.0366,925,891 - 66,940,958-NCBI
RGSC Genome Assembly v3.4356,087,754 - 56,102,821-NCBI
Rat Celera Assembly357,981,902 - 57,996,970-NCBI
Genome Assembly 3.1355,984,129 - 55,999,193-NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Chrna1
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RGD Object Information
RGD ID: 69277
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2015-05-12
Status: ACTIVE