Gene: Chrna1 (cholinergic receptor nicotinic alpha 1 subunit) Rattus norvegicus
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Symbol: Chrna1
Name: cholinergic receptor nicotinic alpha 1 subunit
Description: ENCODES a protein that exhibits acetylcholine-gated cation-selective channel activity; acetylcholine binding (ortholog); acetylcholine receptor activity (ortholog); INVOLVED IN cation transport; skeletal muscle contraction; muscle cell cellular homeostasis (ortholog); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; ASSOCIATED WITH congenital myasthenic syndrome (ortholog); congenital myasthenic syndrome 1A (ortholog); Fibrosis (ortholog); FOUND IN acetylcholine-gated channel complex; cell surface (ortholog); membrane (ortholog); INTERACTS WITH acetylcholine; ammonium chloride; bisphenol A
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: acetylcholine receptor subunit alpha; cholinergic receptor nicotinic alpha polypeptide 1; cholinergic receptor nicotinic alpha polypeptide 1 (muscle); cholinergic receptor, nicotinic, alpha 1; cholinergic receptor, nicotinic, alpha 1 (muscle); cholinergic receptor, nicotinic, alpha polypeptide 1; cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
Orthologs:
Homo sapiens (human) : CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit)  HGNC  AGR
Mus musculus (house mouse) : Chrna1 (cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle))  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Chrna1 (cholinergic receptor nicotinic alpha 1 subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit)
Canis lupus familiaris (dog) : CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chrna1 (cholinergic receptor nicotinic alpha 1 subunit)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0360,445,657 - 60,460,724 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0366,925,891 - 66,940,958 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4356,087,754 - 56,102,821 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1355,984,129 - 55,999,193 (-)NCBI
Celera357,981,902 - 57,996,970 (-)NCBICelera
Cytogenetic Map3q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Chrna1
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69277
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE