Gene: Cyp51 (cytochrome P450, family 51) Rattus norvegicus
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Symbol: Cyp51
Name: cytochrome P450, family 51
Description: ENCODES a protein that exhibits sterol 14-demethylase activity; heme binding (ortholog); INVOLVED IN cholesterol biosynthetic process via 24,25-dihydrolanosterol; steroid biosynthetic process (ortholog); PARTICIPATES IN cholesterol biosynthetic pathway; alendronate pharmacodynamics pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH pleomorphic xanthoastrocytoma (ortholog); Pleomorphic Xanthoastrocytoma (ortholog); FOUND IN intracellular membrane-bounded organelle; endoplasmic reticulum (ortholog); membrane (ortholog); INTERACTS WITH 1-(3-(trifluoromethyl)phenyl)piperazine; 1-benzylpiperazine; 17alpha-ethynylestradiol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Cyp51a1; CYPLI; Cytochrom P450 Lanosterol 14 alpha-demethylase; cytochrome P450 51A1; cytochrome P450 Lanosterol 14 alpha-demethylase; cytochrome P450, subfamily 51; cytochrome P450-14DM; cytochrome P45014DM; cytochrome P450LI; lanosterol 14-alpha demethylase; LDM; MGC93630; P450-14DM; P45014DM; P450LI; RATCP14DM; sterol 14-alpha demethylase
Orthologs:
Homo sapiens (human) : CYP51A1 (cytochrome P450 family 51 subfamily A member 1)  HGNC  AGR
Mus musculus (house mouse) : Cyp51 (cytochrome P450, family 51)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : LOC102027002 (lanosterol 14-alpha demethylase)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100985833 (lanosterol 14-alpha demethylase)
Canis lupus familiaris (dog) : CYP51A1 (cytochrome P450, family 51, subfamily A, polypeptide 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101955024 (lanosterol 14-alpha demethylase)
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Is Marker For: Strains:   BB/OK  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0427,175,564 - 27,194,018 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0427,078,790 - 27,097,244 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4426,752,677 - 26,771,131 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1426,758,233 - 26,776,686 (+)NCBI
Celera425,462,810 - 25,481,264 (+)NCBICelera
Cytogenetic Map4q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cyp51
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 2481
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE