Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of ARID5A mRNA] | CTD | PMID:31150632 | 1,2-dimethylhydrazine | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of ARID5A mRNA | CTD | PMID:22206623 | 15-acetyldeoxynivalenol | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | 15-acetyldeoxynivalenol results in increased expression of ARID5A mRNA | CTD | PMID:23792671 | 17beta-estradiol | multiple interactions | ISO | ARID5A (Homo sapiens) | 6480464 | ARID5A protein inhibits the reaction [Estradiol results in increased activity of ESR1 protein] | CTD | PMID:15941852 | 17beta-estradiol | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Estradiol results in increased expression of ARID5A mRNA | CTD | PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Arid5a (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ARID5A mRNA | CTD | PMID:21570461 and PMID:26377647 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ARID5A mRNA | CTD | PMID:33387578 and PMID:34747641 | 3,3',5,5'-tetrabromobisphenol A | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | tetrabromobisphenol A results in increased expression of ARID5A mRNA | CTD | PMID:25172293 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | ARID5A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of ARID5A mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | ARID5A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of ARID5A mRNA | CTD | PMID:28628672 | 4-hydroxynon-2-enal | decreases expression | ISO | Arid5a (Mus musculus) | 6480464 | 4-hydroxy-2-nonenal results in decreased expression of ARID5A mRNA | CTD | PMID:19191707 | 4-hydroxyphenyl retinamide | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Fenretinide results in increased expression of ARID5A mRNA | CTD | PMID:28973697 | acrolein | multiple interactions | ISO | ARID5A (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ARID5A mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of ARID5A mRNA | CTD | PMID:32699268 | acrylamide | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Acrylamide results in increased expression of ARID5A mRNA | CTD | PMID:30807115 | afimoxifene | multiple interactions | ISO | ARID5A (Homo sapiens) | 6480464 | ARID5A protein inhibits the reaction [afimoxifene results in increased activity of ESR1 protein] | CTD | PMID:15941852 | aflatoxin B1 | decreases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of ARID5A mRNA | CTD | PMID:22100608 | alpha-pinene | multiple interactions | ISO | ARID5A (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ARID5A mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of ARID5A mRNA | CTD | PMID:32699268 | amiodarone | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Amiodarone results in increased expression of ARID5A mRNA | CTD | PMID:19774075 | aristolochic acid A | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of ARID5A mRNA | CTD | PMID:33212167 | atrazine | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Atrazine results in increased expression of ARID5A mRNA | CTD | PMID:22378314 | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of ARID5A gene | CTD | PMID:35440735 | benzo[a]pyrene | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of ARID5A mRNA | CTD | PMID:21569818 and PMID:22228805 | benzo[a]pyrene | decreases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of ARID5A mRNA | CTD | PMID:32234424 | benzo[a]pyrene | affects methylation | ISO | ARID5A (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ARID5A promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | Arid5a (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of ARID5A mRNA | CTD | PMID:25908611 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ARID5A mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ARID5A mRNA | CTD | PMID:30816183 and PMID:32528016 | bisphenol A | decreases expression | ISO | Arid5a (Mus musculus) | 6480464 | bisphenol A results in decreased expression of ARID5A mRNA | CTD | PMID:25594700 and PMID:30951980 | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of ARID5A mRNA | CTD | PMID:32479839 | butanal | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of ARID5A mRNA | CTD | PMID:26079696 | caffeine | increases phosphorylation | ISO | ARID5A (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of ARID5A protein | CTD | PMID:35688186 | carbon nanotube | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | carbon nanotube | affects expression | ISO | Arid5a (Mus musculus) | 6480464 | Nanotubes and Carbon affects the expression of ARID5A mRNA | CTD | PMID:31978390 | cefaloridine | increases expression | EXP | | 6480464 | Cephaloridine results in increased expression of ARID5A mRNA | CTD | PMID:18500788 | chlorpyrifos | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of ARID5A mRNA | CTD | PMID:34289071 | dexamethasone | multiple interactions | ISO | ARID5A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of ARID5A mRNA | CTD | PMID:28628672 | diclofenac | decreases expression | ISO | Arid5a (Mus musculus) | 6480464 | Diclofenac results in decreased expression of ARID5A mRNA | CTD | PMID:35537566 | dioxygen | multiple interactions | ISO | Arid5a (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of ARID5A mRNA | CTD | PMID:30529165 | disodium selenite | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of ARID5A mRNA | CTD | PMID:18175754 | doxorubicin | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Doxorubicin results in increased expression of ARID5A mRNA | CTD | PMID:36227756 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of ARID5A mRNA | CTD | PMID:29391264 | fluoranthene | multiple interactions | ISO | Arid5a (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in increased expression of ARID5A mRNA | CTD | PMID:28329830 | FR900359 | increases phosphorylation | ISO | ARID5A (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of ARID5A protein | CTD | PMID:37730182 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of ARID5A mRNA | CTD | PMID:33387578 | graphite | affects expression | EXP | | 6480464 | Graphite affects the expression of ARID5A mRNA | CTD | PMID:29933104 | indometacin | multiple interactions | ISO | ARID5A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of ARID5A mRNA | CTD | PMID:28628672 | melphalan | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Melphalan results in increased expression of ARID5A mRNA | CTD | PMID:22363485 | menadione | affects expression | ISO | ARID5A (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of ARID5A mRNA | CTD | PMID:20044591 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of ARID5A gene | CTD | PMID:35440735 | methylmercury chloride | increases expression | EXP | | 6480464 | methylmercuric chloride results in increased expression of ARID5A mRNA | CTD | PMID:31378766 | Muraglitazar | decreases expression | EXP | | 6480464 | muraglitazar results in decreased expression of ARID5A mRNA | CTD | PMID:21515302 | N-methyl-4-phenylpyridinium | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of ARID5A mRNA | CTD | PMID:24810058 | naphthalene | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | naphthalene results in increased expression of ARID5A mRNA | CTD | PMID:18978301 | nickel atom | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Nickel results in increased expression of ARID5A mRNA | CTD | PMID:24768652 and PMID:25583101 | ozone | multiple interactions | ISO | ARID5A (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ARID5A mRNA more ... | CTD | PMID:32699268 | paracetamol | affects expression | ISO | Arid5a (Mus musculus) | 6480464 | Acetaminophen affects the expression of ARID5A mRNA | CTD | PMID:17562736 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of ARID5A mRNA | CTD | PMID:33387578 | pentanal | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | pentanal results in increased expression of ARID5A mRNA | CTD | PMID:26079696 | phenobarbital | multiple interactions | ISO | Arid5a (Mus musculus) | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in increased expression of ARID5A mRNA] | CTD | PMID:19482888 | phenobarbital | affects expression | ISO | ARID5A (Homo sapiens) | 6480464 | Phenobarbital affects the expression of ARID5A mRNA | CTD | PMID:19159669 | phenobarbital | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Phenobarbital results in increased expression of ARID5A mRNA | CTD | PMID:19482888 | pregnenolone 16alpha-carbonitrile | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in increased expression of ARID5A mRNA | CTD | PMID:28903501 | raloxifene | multiple interactions | ISO | ARID5A (Homo sapiens) | 6480464 | ARID5A protein inhibits the reaction [Raloxifene Hydrochloride results in increased activity of ESR1 protein] | CTD | PMID:15941852 | silicon dioxide | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of ARID5A mRNA | CTD | PMID:25895662 | silicon dioxide | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Silicon Dioxide results in increased expression of ARID5A mRNA | CTD | PMID:19073995 and PMID:33720480 | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of ARID5A mRNA | CTD | PMID:19281266 | sunitinib | decreases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of ARID5A mRNA | CTD | PMID:31533062 | Tesaglitazar | decreases expression | EXP | | 6480464 | tesaglitazar results in decreased expression of ARID5A mRNA | CTD | PMID:21515302 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of ARID5A mRNA | CTD | PMID:31150632 | tetrachloromethane | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of ARID5A mRNA | CTD | PMID:31919559 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of ARID5A mRNA] | CTD | PMID:31150632 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of ARID5A mRNA | CTD | PMID:34492290 | titanium dioxide | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | titanium dioxide results in increased expression of ARID5A mRNA | CTD | PMID:27760801 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of ARID5A mRNA | CTD | PMID:33387578 | Triptolide | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | triptolide results in increased expression of ARID5A mRNA | CTD | PMID:32835833 | triptonide | affects expression | ISO | Arid5a (Mus musculus) | 6480464 | triptonide affects the expression of ARID5A mRNA | CTD | PMID:33045310 | troglitazone | decreases expression | EXP | | 6480464 | troglitazone results in decreased expression of ARID5A mRNA | CTD | PMID:21515302 | trovafloxacin | decreases expression | ISO | Arid5a (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of ARID5A mRNA | CTD | PMID:35537566 | tungsten | decreases expression | ISO | Arid5a (Mus musculus) | 6480464 | Tungsten results in decreased expression of ARID5A mRNA | CTD | PMID:30912803 | valproic acid | increases methylation | ISO | ARID5A (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of ARID5A gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | Arid5a (Mus musculus) | 6480464 | Valproic Acid results in increased expression of ARID5A mRNA | CTD | PMID:21427059 | valproic acid | increases expression | ISO | ARID5A (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ARID5A mRNA | CTD | PMID:29154799 | |