(1->4)-beta-D-glucan multiple interactions ISO Pfkfb1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PFKFB1 mRNA CTD PMID:36331819 1,2-dimethylhydrazine decreases expression ISO Pfkfb1 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of PFKFB1 mRNA CTD PMID:22206623 17beta-estradiol decreases expression ISO PFKFB1 (Homo sapiens) 6480464 Estradiol results in decreased expression of PFKFB1 mRNA CTD PMID:20106945 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of PFKFB1 mRNA CTD PMID:32145629 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Pfkfb1 (Mus musculus) 6480464 [2 more ... CTD PMID:25510870 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Pfkfb1 (Mus musculus) 6480464 [2 more ... CTD PMID:25510870 2,3,4,7,8-Pentachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:21724226 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Pfkfb1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of PFKFB1 mRNA CTD PMID:19770486 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO PFKFB1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of PFKFB1 mRNA CTD PMID:19692669 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of PFKFB1 mRNA CTD PMID:21215274 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of PFKFB1 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO PFKFB1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of PFKFB1 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Pfkfb1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PFKFB1 promoter] CTD PMID:19654925 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:21724226 2,4-dinitrotoluene affects expression EXP 6480464 2 and 4-dinitrotoluene affects the expression of PFKFB1 mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of PFKFB1 mRNA CTD PMID:21346803 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of PFKFB1 mRNA CTD PMID:28522335 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1 and 2-dithiol-3-thione results in decreased expression of PFKFB1 mRNA CTD PMID:19162173 4,4'-sulfonyldiphenol decreases expression ISO Pfkfb1 (Mus musculus) 6480464 bisphenol S results in decreased expression of PFKFB1 mRNA CTD PMID:33297965 4-hydroxyphenyl retinamide decreases expression ISO Pfkfb1 (Mus musculus) 6480464 Fenretinide results in decreased expression of PFKFB1 mRNA CTD PMID:28973697 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of PFKFB1 mRNA CTD PMID:24780913 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of PFKFB1 mRNA CTD PMID:28959563 aflatoxin B1 affects expression ISO PFKFB1 (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of PFKFB1 protein CTD PMID:20106945 aflatoxin B1 decreases methylation ISO PFKFB1 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of PFKFB1 gene CTD PMID:27153756 aflatoxin B1 decreases expression ISO PFKFB1 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of PFKFB1 mRNA CTD PMID:22100608 more ... aflatoxin B1 decreases expression ISO Pfkfb1 (Mus musculus) 6480464 Aflatoxin B1 results in decreased expression of PFKFB1 mRNA CTD PMID:19770486 amiodarone increases expression ISO Pfkfb1 (Mus musculus) 6480464 Amiodarone results in increased expression of PFKFB1 mRNA CTD PMID:24535564 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PFKFB1 mRNA CTD PMID:16483693 benzene affects expression EXP 6480464 Benzene affects the expression of PFKFB1 mRNA CTD PMID:15878777 benzo[a]pyrene decreases expression ISO PFKFB1 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of PFKFB1 mRNA CTD PMID:20106945 more ... benzo[a]pyrene affects methylation ISO PFKFB1 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of PFKFB1 exon CTD PMID:27901495 benzo[a]pyrene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with 1 more ... CTD PMID:18711122 benzo[a]pyrene decreases expression ISO Pfkfb1 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of PFKFB1 mRNA CTD PMID:19770486 benzo[b]fluoranthene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of PFKFB1 mRNA CTD PMID:18711122 beta-D-fructofuranose 2,6-bisphosphate decreases abundance ISO Pfkfb1 (Mus musculus) 6480464 PFKFB1 gene mutant form results in decreased abundance of fructose 2 and 6-diphosphate CTD PMID:31974165 beta-hexachlorocyclohexane decreases expression ISO Pfkfb1 (Mus musculus) 6480464 beta-hexachlorocyclohexane results in decreased expression of PFKFB1 mRNA CTD PMID:25270620 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of PFKFB1 mRNA CTD PMID:25181051 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PFKFB1 mRNA CTD PMID:30816183 more ... bisphenol A decreases methylation ISO Pfkfb1 (Mus musculus) 6480464 bisphenol A results in decreased methylation of PFKFB1 promoter CTD PMID:27312807 bromobenzene increases expression EXP 6480464 bromobenzene results in increased expression of PFKFB1 mRNA CTD PMID:32479839 cantharidin decreases expression ISO Pfkfb1 (Mus musculus) 6480464 Cantharidin results in decreased expression of PFKFB1 mRNA CTD PMID:36907384 CGP 52608 multiple interactions ISO PFKFB1 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to PFKFB1 gene] CTD PMID:28238834 chloroprene increases expression EXP 6480464 Chloroprene results in increased expression of PFKFB1 mRNA CTD PMID:23125180 clofibric acid affects expression EXP 6480464 Clofibric Acid affects the expression of PFKFB1 mRNA CTD PMID:17602206 cyclosporin A decreases expression ISO Pfkfb1 (Mus musculus) 6480464 Cyclosporine results in decreased expression of PFKFB1 mRNA CTD PMID:23830897 cyclosporin A increases expression ISO PFKFB1 (Homo sapiens) 6480464 Cyclosporine results in increased expression of PFKFB1 mRNA CTD PMID:27989131 cyclosporin A decreases expression ISO PFKFB1 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of PFKFB1 mRNA CTD PMID:20106945 and PMID:23830897 D-glucopyranose 6-phosphate multiple interactions ISO Pfkfb1 (Mus musculus) 6480464 PFKFB1 gene mutant form inhibits the reaction [Metformin results in decreased abundance of Glucose-6-Phosphate metabolite] CTD PMID:31974165 D-glucopyranose 6-phosphate increases abundance ISO Pfkfb1 (Mus musculus) 6480464 PFKFB1 gene mutant form results in increased abundance of Glucose-6-Phosphate CTD PMID:31974165 dibenz[a,h]anthracene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with 1 more ... CTD PMID:18711122 dorsomorphin multiple interactions ISO PFKFB1 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PFKFB1 mRNA CTD PMID:27188386 doxorubicin decreases expression ISO Pfkfb1 (Mus musculus) 6480464 Doxorubicin results in decreased expression of PFKFB1 mRNA CTD PMID:31768571 and PMID:36227756 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of PFKFB1 mRNA CTD PMID:29391264 epoxiconazole decreases expression ISO Pfkfb1 (Mus musculus) 6480464 epoxiconazole results in decreased expression of PFKFB1 mRNA CTD PMID:35436446 ethanol multiple interactions ISO Pfkfb1 (Mus musculus) 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in decreased expression of PFKFB1 mRNA CTD PMID:30517762 flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of PFKFB1 mRNA CTD PMID:18035473 fluoranthene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with fluoranthene] affects the expression of PFKFB1 mRNA CTD PMID:18711122 flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of PFKFB1 mRNA CTD PMID:24136188 flutamide increases expression EXP 6480464 Flutamide results in increased expression of PFKFB1 mRNA CTD PMID:21525395 and PMID:24793618 furan increases expression EXP 6480464 furan results in increased expression of PFKFB1 mRNA CTD PMID:26194646 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of PFKFB1 mRNA CTD PMID:33387578 glyceraldehyde 3-phosphate decreases chemical synthesis ISO Pfkfb1 (Mus musculus) 6480464 PFKFB1 gene mutant form results in decreased chemical synthesis of Glyceraldehyde 3-Phosphate metabolite CTD PMID:31974165 glyceraldehyde 3-phosphate multiple interactions ISO Pfkfb1 (Mus musculus) 6480464 PFKFB1 gene mutant form inhibits the reaction [Metformin results in increased abundance of Glyceraldehyde 3-Phosphate metabolite] CTD PMID:31974165 Heptachlor epoxide decreases expression ISO Pfkfb1 (Mus musculus) 6480464 Heptachlor Epoxide results in decreased expression of PFKFB1 mRNA CTD PMID:25270620 indole-3-methanol affects expression EXP 6480464 indole-3-carbinol affects the expression of PFKFB1 mRNA CTD PMID:21396975 L-ascorbic acid multiple interactions EXP 6480464 Ascorbic Acid inhibits the reaction [Iodoacetamide affects the activity of PFKFB1 protein] CTD PMID:6092364 Lasiocarpine decreases expression ISO PFKFB1 (Homo sapiens) 6480464 lasiocarpine results in decreased expression of PFKFB1 mRNA CTD PMID:32234424 and PMID:35690182 metacetamol decreases expression ISO Pfkfb1 (Mus musculus) 6480464 3-hydroxyacetanilide results in decreased expression of PFKFB1 mRNA CTD PMID:18544908 metformin increases expression EXP 6480464 Metformin results in increased expression of PFKFB1 mRNA CTD PMID:31324951 metformin multiple interactions ISO Pfkfb1 (Mus musculus) 6480464 PFKFB1 gene mutant form inhibits the reaction [Metformin results in decreased abundance of Glucose-6-Phosphate metabolite] and PFKFB1 gene mutant form inhibits the reaction [Metformin results in increased abundance of Glyceraldehyde 3-Phosphate metabolite] CTD PMID:31974165 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of PFKFB1 mRNA CTD PMID:30467583 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of PFKFB1 mRNA CTD PMID:28943392 N-Nitrosopyrrolidine decreases expression ISO PFKFB1 (Homo sapiens) 6480464 N-Nitrosopyrrolidine results in decreased expression of PFKFB1 mRNA CTD PMID:32234424 and PMID:35690182 nitrofen increases expression EXP 6480464 nitrofen results in increased expression of PFKFB1 mRNA CTD PMID:33484710 O-methyleugenol decreases expression ISO PFKFB1 (Homo sapiens) 6480464 methyleugenol results in decreased expression of PFKFB1 mRNA CTD PMID:32234424 and PMID:35690182 obeticholic acid increases expression ISO PFKFB1 (Homo sapiens) 6480464 obeticholic acid results in increased expression of PFKFB1 mRNA CTD PMID:27939613 oxycodone increases expression EXP 6480464 Oxycodone results in increased expression of PFKFB1 mRNA CTD PMID:23439660 ozone increases expression EXP 6480464 Ozone results in increased expression of PFKFB1 mRNA CTD PMID:25838073 paracetamol affects expression ISO Pfkfb1 (Mus musculus) 6480464 Acetaminophen affects the expression of PFKFB1 mRNA CTD PMID:17562736 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of PFKFB1 mRNA CTD PMID:33387578 paracetamol decreases expression ISO PFKFB1 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of PFKFB1 mRNA CTD PMID:21420995 and PMID:29067470 paracetamol decreases expression ISO Pfkfb1 (Mus musculus) 6480464 Acetaminophen results in decreased expression of PFKFB1 mRNA CTD PMID:18544908 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of PFKFB1 mRNA CTD PMID:32680482 PCB138 multiple interactions ISO Pfkfb1 (Mus musculus) 6480464 [2 more ... CTD PMID:25510870 perfluorooctane-1-sulfonic acid affects expression ISO Pfkfb1 (Mus musculus) 6480464 perfluorooctane sulfonic acid affects the expression of PFKFB1 mRNA CTD PMID:19429403 perfluorooctane-1-sulfonic acid multiple interactions ISO Pfkfb1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PFKFB1 mRNA CTD PMID:36331819 perfluorooctanoic acid affects expression ISO Pfkfb1 (Mus musculus) 6480464 perfluorooctanoic acid affects the expression of PFKFB1 mRNA CTD PMID:19429403 permethrin increases expression ISO PFKFB1 (Homo sapiens) 6480464 Permethrin results in increased expression of PFKFB1 mRNA CTD PMID:37047231 phenformin decreases expression EXP 6480464 Phenformin results in decreased expression of PFKFB1 mRNA CTD PMID:31324951 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of PFKFB1 mRNA CTD PMID:19162173 pirinixic acid increases expression ISO Pfkfb1 (Mus musculus) 6480464 pirinixic acid results in increased expression of PFKFB1 mRNA CTD PMID:18301758 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of PFKFB1 mRNA CTD PMID:19162173 pirinixic acid multiple interactions ISO Pfkfb1 (Mus musculus) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of PFKFB1 mRNA CTD PMID:19710929 resveratrol increases expression EXP 6480464 resveratrol results in increased expression of PFKFB1 mRNA CTD PMID:25905778 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of PFKFB1 mRNA CTD PMID:28374803 SB 431542 multiple interactions ISO PFKFB1 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PFKFB1 mRNA CTD PMID:27188386 sodium arsenite decreases expression ISO PFKFB1 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of PFKFB1 mRNA CTD PMID:29301061 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of PFKFB1 mRNA CTD PMID:25905778 sulforaphane increases expression ISO Pfkfb1 (Mus musculus) 6480464 sulforaphane results in increased expression of PFKFB1 mRNA CTD PMID:30529165 sunitinib decreases expression ISO PFKFB1 (Homo sapiens) 6480464 Sunitinib results in decreased expression of PFKFB1 mRNA CTD PMID:31533062 tetrachloromethane multiple interactions ISO Pfkfb1 (Mus musculus) 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in decreased expression of PFKFB1 mRNA CTD PMID:30517762 thiabendazole increases expression EXP 6480464 Thiabendazole results in increased expression of PFKFB1 mRNA CTD PMID:18539377 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of PFKFB1 mRNA CTD PMID:23411599 and PMID:34492290 thioacetamide multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of PFKFB1 mRNA CTD PMID:28943392 titanium dioxide decreases expression ISO Pfkfb1 (Mus musculus) 6480464 titanium dioxide results in decreased expression of PFKFB1 mRNA CTD PMID:23557971 tris(2-butoxyethyl) phosphate affects expression ISO PFKFB1 (Homo sapiens) 6480464 tris(2-butoxyethyl) phosphate affects the expression of PFKFB1 mRNA CTD PMID:29024780 troglitazone increases expression ISO Pfkfb1 (Mus musculus) 6480464 troglitazone results in increased expression of PFKFB1 mRNA CTD PMID:28973697 urethane decreases expression ISO PFKFB1 (Homo sapiens) 6480464 Urethane results in decreased expression of PFKFB1 mRNA CTD PMID:28818685 valdecoxib decreases expression EXP 6480464 valdecoxib results in decreased expression of PFKFB1 mRNA CTD PMID:24136188 valproic acid increases expression ISO Pfkfb1 (Mus musculus) 6480464 Valproic Acid results in increased expression of PFKFB1 mRNA CTD PMID:24535564 valproic acid decreases expression ISO PFKFB1 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of PFKFB1 mRNA CTD PMID:26272509 and PMID:29154799 valproic acid multiple interactions ISO PFKFB1 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PFKFB1 mRNA CTD PMID:27188386