Gene: Scn1a (sodium voltage-gated channel alpha subunit 1) Rattus norvegicus
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Symbol: Scn1a
Name: sodium voltage-gated channel alpha subunit 1
Description: ENCODES a protein that exhibits sodium ion binding; voltage-gated sodium channel activity; INVOLVED IN neuronal action potential; action potential (ortholog); adult walking behavior (ortholog); ASSOCIATED WITH Seizures, Febrile; Abnormalities, Multiple (ortholog); adolescence-adult electroclinical syndrome (ortholog); FOUND IN plasma membrane; voltage-gated sodium channel complex; axon (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether; 2,2',5,5'-tetrachlorobiphenyl
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: sodium channel protein brain I subunit alpha; sodium channel protein type 1 subunit alpha; sodium channel protein type I subunit alpha; sodium channel protein, brain I subunit alpha; sodium channel voltage-gated type I alpha polypeptide; sodium channel, voltage-gated, type 1, alpha polypeptide; sodium channel, voltage-gated, type I, alpha; sodium channel, voltage-gated, type I, alpha polypeptide; sodium channel, voltage-gated, type I, alpha subunit; voltage-gated sodium channel subunit alpha Nav1.1
Orthologs:
Homo sapiens (human) : SCN1A (sodium voltage-gated channel alpha subunit 1)  HGNC
Mus musculus (house mouse) : Scn1a (sodium channel, voltage-gated, type I, alpha)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Scn1a (sodium voltage-gated channel alpha subunit 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SCN1A (sodium voltage-gated channel alpha subunit 1)
Canis lupus familiaris (dog) : SCN1A (sodium voltage-gated channel alpha subunit 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scn1a (sodium voltage-gated channel alpha subunit 1)
more info ...
Allele / Splice: Scn1am1Kyo   Scn1am2Kyo  
Genetic Models: F344-Scn1am1Kyo F344-Scn1am2Kyo F344-Scn1am1Kyo.GRY-Cacna1agry/Okym
Is Marker For: Strains:   F344-Scn1am2Kyo   F344-Scn1am1Kyo   F344.NER-(D1Mgh6-D1Rat73)(D5Mgh4-D5Rat36)Scn1am1/Kyo  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0352,388,811 - 52,533,365 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0359,016,641 - 59,135,580 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4348,238,528 - 48,364,143 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1348,134,899 - 48,260,515 (-)NCBI
Celera350,540,798 - 50,655,298 (-)NCBI
Cytogenetic Map3q21NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Scn1a
NCBI Gene
Ensembl Gene
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RGD Object Information
RGD ID: 69364
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2017-09-05
Status: ACTIVE