Annotation (Toggle Detail/Summary View) Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-alpha-tocopherol | increases expression | EXP | | 6480464 | alpha-Tocopherol results in increased expression of FMO1 mRNA | CTD | PMID:16908007 | 1-naphthyl isothiocyanate | decreases expression | ISO | RGD:10593 | 6480464 | 1-Naphthylisothiocyanate results in decreased expression of FMO1 mRNA | CTD | PMID:15913567 | 1-naphthyl isothiocyanate | decreases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in decreased expression of FMO1 mRNA | CTD | PMID:17522070 | 17alpha-ethynylestradiol | affects expression | ISO | RGD:10593 | 6480464 | Ethinyl Estradiol affects the expression of FMO1 mRNA | CTD | PMID:17555576 | 17beta-estradiol | decreases expression | ISO | RGD:10593 | 6480464 | Estradiol results in decreased expression of FMO1 mRNA | CTD | PMID:14664709 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of FMO1 protein | CTD | PMID:21966433 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | EXP | | 6480464 | [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of FMO1 mRNA | CTD | PMID:16984957 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:10593 | 6480464 | [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of FMO1 mRNA | CTD | PMID:16214954 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:10593 | 6480464 | Tetrachlorodibenzodioxin affects the expression of FMO1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FMO1 mRNA | CTD | PMID:11752688 more ... | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of FMO1 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:10593 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FMO1 mRNA | CTD | PMID:19770486 more ... | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FMO1 mRNA | CTD | PMID:11752688 more ... | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:10593 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FMO1 mRNA | CTD | PMID:18796159 more ... | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FMO1 mRNA | CTD | PMID:18796159 more ... | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:10593 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FMO1 mRNA | CTD | PMID:18765683 more ... | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FMO1 mRNA | CTD | PMID:16054898 more ... | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:10593 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FMO1 mRNA | CTD | PMID:18765683 more ... | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:10593 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FMO1 mRNA | CTD | PMID:19933214 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FMO1 mRNA | CTD | PMID:11752688 more ... | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:10593 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FMO1 mRNA | CTD | PMID:18765683 PMID:18796159 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of FMO1 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of FMO1 mRNA | CTD | PMID:21346803 | 3,3',4,4',5-pentachlorobiphenyl | multiple interactions | EXP | | 6480464 | [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of FMO1 mRNA | CTD | PMID:16984957 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RGD:10593 | 6480464 | [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FMO1 mRNA | CTD | PMID:16054899 | 3H-1,2-dithiole-3-thione | decreases expression | EXP | | 6480464 | 1,2-dithiol-3-thione results in decreased expression of FMO1 mRNA | CTD | PMID:19162173 | 4,4'-diaminodiphenylmethane | increases expression | ISO | RGD:10593 | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of FMO1 mRNA | CTD | PMID:18648102 | 4-aminophenol | multiple interactions | ISO | RGD:736452 | 6480464 | [[FMO1 protein co-treated with NADP] results in increased metabolism of 4-fluoro-N-methylaniline] which results in increased chemical synthesis of 4-aminophenol | CTD | PMID:20369854 | 4-fluoroaniline | multiple interactions | ISO | RGD:736452 | 6480464 | [[FMO1 protein co-treated with NADP] results in increased metabolism of 4-fluoro-N-methylaniline] which results in increased chemical synthesis of 4-fluoroaniline | CTD | PMID:20369854 | 6-propyl-2-thiouracil | affects expression | EXP | | 6480464 | Propylthiouracil affects the expression of FMO1 mRNA | CTD | PMID:19483382 | amiodarone | affects expression | EXP | | 6480464 | Amiodarone affects the expression of FMO1 mRNA | CTD | PMID:19483382 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of FMO1 mRNA | CTD | PMID:16483693 | Aroclor 1254 | increases expression | ISO | RGD:736452 | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of FMO1 mRNA | CTD | PMID:17851650 | benzbromarone | affects expression | EXP | | 6480464 | Benzbromarone affects the expression of FMO1 mRNA | CTD | PMID:19483382 | benzo[a]pyrene | increases expression | ISO | RGD:10593 | 6480464 | Benzo(a)pyrene results in increased expression of FMO1 mRNA | CTD | PMID:19770486 | benzo[a]pyrene | multiple interactions | ISO | RGD:10593 | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of FMO1 mRNA] | CTD | PMID:22228805 | benzo[a]pyrene | decreases expression | ISO | RGD:10593 | 6480464 | Benzo(a)pyrene results in decreased expression of FMO1 mRNA | CTD | PMID:21569818 | benzo[a]pyrene | increases expression | ISO | RGD:736452 | 6480464 | Benzo(a)pyrene results in increased expression of FMO1 mRNA | CTD | PMID:17879257 | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of FMO1 mRNA | CTD | PMID:15056800 | chloroform | decreases expression | EXP | | 6480464 | Chloroform results in decreased expression of FMO1 mRNA | CTD | PMID:17522070 | clofibrate | multiple interactions | ISO | RGD:10593 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of FMO1 mRNA; more ... | CTD | PMID:17585979 | clofibrate | affects expression | EXP | | 6480464 | Clofibrate affects the expression of FMO1 mRNA | CTD | PMID:19483382 | clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of FMO1 mRNA | CTD | PMID:17602206 | corticosterone | increases expression | EXP | | 6480464 | Corticosterone results in increased expression of FMO1 mRNA | CTD | PMID:15755911 | coumarin | decreases expression | EXP | | 6480464 | coumarin results in decreased expression of FMO1 mRNA | CTD | PMID:18480146 | cyclosporin A | decreases expression | ISO | RGD:10593 | 6480464 | Cyclosporine results in decreased expression of FMO1 mRNA | CTD | PMID:19770486 | cytarabine | decreases expression | ISO | RGD:736452 | 6480464 | Cytarabine results in decreased expression of FMO1 mRNA | CTD | PMID:21198554 | dexamethasone | affects expression | EXP | | 6480464 | Dexamethasone affects the expression of FMO1 mRNA | CTD | PMID:15102944 | dexamethasone | multiple interactions | ISO | RGD:10593 | 6480464 | [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FMO1 mRNA | CTD | PMID:16054899 | diazoxide | increases expression | ISO | RGD:10593 | 6480464 | Isoproterenol results in increased expression of FMO1 mRNA | CTD | PMID:20003209 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of FMO1 mRNA | CTD | PMID:21266533 | diethylstilbestrol | increases expression | ISO | RGD:10593 | 6480464 | Diethylstilbestrol results in increased expression of FMO1 mRNA | CTD | PMID:15171707 | diethylstilbestrol | decreases expression | ISO | RGD:10593 | 6480464 | Diethylstilbestrol results in decreased expression of FMO1 mRNA | CTD | PMID:16636312 | endosulfan | decreases expression | ISO | RGD:10593 | 6480464 | Endosulfan results in decreased expression of FMO1 mRNA | CTD | PMID:22515965 | erythromycin estolate | decreases expression | EXP | | 6480464 | Erythromycin Estolate results in decreased expression of FMO1 mRNA | CTD | PMID:17522070 | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of FMO1 mRNA | CTD | PMID:16946407 | ethanol | increases expression | ISO | RGD:10593 | 6480464 | Ethanol results in increased expression of FMO1 mRNA | CTD | PMID:19167417 | fenofibrate | multiple interactions | EXP | | 6480464 | [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of FMO1 mRNA | CTD | PMID:18253720 | fenthion | increases oxidation | ISO | RGD:736452 | 6480464 | FMO1 protein results in increased oxidation of Fenthion | CTD | PMID:14976351 | hydrogen peroxide | decreases expression | ISO | RGD:736452 | 6480464 | Hydrogen Peroxide results in decreased expression of FMO1 mRNA | CTD | PMID:12419474 | isoprenaline | increases expression | ISO | RGD:10593 | 6480464 | Isoproterenol results in increased expression of FMO1 mRNA | CTD | PMID:20003209 | kojic acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of FMO1 mRNA; more ... | CTD | PMID:18544905 | L-ascorbic acid | multiple interactions | ISO | RGD:736452 | 6480464 | [Quercetin co-treated with Ascorbic Acid] results in decreased expression of FMO1 mRNA | CTD | PMID:17639512 | L-ethionine | affects expression | EXP | | 6480464 | Ethionine affects the expression of FMO1 mRNA | CTD | PMID:19483382 | methimazole | increases oxidation | ISO | RGD:736452 | 6480464 | FMO1 protein results in increased oxidation of Methimazole | CTD | PMID:14976351 | methimazole | multiple interactions | EXP | | 6480464 | Methimazole inhibits the reaction [[[FMO1 protein co-treated with NADP] results in increased metabolism of 4-fluoro-N-methylaniline] which results in increased chemical synthesis of 4-(methylamino)phenol]; more ... | CTD | PMID:20369854 | monocrotaline | multiple interactions | ISO | RGD:10593 | 6480464 | [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FMO1 mRNA | CTD | PMID:21224054 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of FMO1 mRNA | CTD | PMID:17602206 | N-nitrosodiethylamine | decreases expression | EXP | | 6480464 | Diethylnitrosamine results in decreased expression of FMO1 mRNA | CTD | PMID:19638242 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of FMO1 mRNA | CTD | PMID:18253720 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of FMO1 mRNA; more ... | CTD | PMID:18544905 | N-nitrosodimethylamine | decreases expression | EXP | | 6480464 | Dimethylnitrosamine results in decreased expression of FMO1 mRNA | CTD | PMID:17072980 | NADP zwitterion | multiple interactions | EXP | | 6480464 | [FMO1 protein co-treated with NADP] results in increased metabolism of 4-fluoro-N-methylaniline; more ... | CTD | PMID:20369854 | NADP zwitterion | multiple interactions | ISO | RGD:736452 | 6480464 | [[FMO1 protein co-treated with NADP] results in increased metabolism of 4-fluoro-N-methylaniline] which results in increased chemical synthesis of 4-aminophenol; more ... | CTD | PMID:20369854 | NADP(+) | multiple interactions | ISO | RGD:736452 | 6480464 | [[FMO1 protein co-treated with NADP] results in increased metabolism of 4-fluoro-N-methylaniline] which results in increased chemical synthesis of 4-aminophenol; more ... | CTD | PMID:20369854 | NADP(+) | multiple interactions | EXP | | 6480464 | [FMO1 protein co-treated with NADP] results in increased metabolism of 4-fluoro-N-methylaniline; more ... | CTD | PMID:20369854 | nitroglycerin | decreases expression | EXP | | 6480464 | Nitroglycerin results in decreased expression of FMO1 mRNA | CTD | PMID:12102619 | omeprazole | affects expression | EXP | | 6480464 | Omeprazole affects the expression of FMO1 mRNA | CTD | PMID:19483382 | oxycodone | affects expression | EXP | | 6480464 | Oxycodone affects the expression of FMO1 mRNA | CTD | PMID:20487198 | ozone | decreases expression | ISO | RGD:10593 | 6480464 | Ozone results in decreased expression of FMO1 mRNA | CTD | PMID:12763052 | paracetamol | multiple interactions | ISO | RGD:10593 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of FMO1 mRNA; more ... | CTD | PMID:17585979 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of FMO1 mRNA | CTD | PMID:17202762 PMID:17522070 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of FMO1 mRNA | CTD | PMID:17522070 PMID:17202762 | paracetamol | affects expression | ISO | RGD:10593 | 6480464 | Acetaminophen affects the expression of FMO1 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | RGD:10593 | 6480464 | Acetaminophen results in increased expression of FMO1 mRNA | CTD | PMID:11264010 | perfluorooctanoic acid | decreases expression | EXP | | 6480464 | perfluorooctanoic acid results in decreased expression of FMO1 mRNA | CTD | PMID:19162173 | phenobarbital | increases expression | ISO | RGD:10593 | 6480464 | Phenobarbital results in increased expression of FMO1 mRNA | CTD | PMID:19482888 | phenobarbital | multiple interactions | ISO | RGD:10593 | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in increased expression of FMO1 mRNA] | CTD | PMID:19482888 | phenobarbital | decreases expression | EXP | | 6480464 | Phenobarbital results in decreased expression of FMO1 mRNA | CTD | PMID:19162173 | phenytoin | multiple interactions | ISO | RGD:10593 | 6480464 | [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FMO1 mRNA | CTD | PMID:21224054 | phlorizin | decreases expression | ISO | RGD:10593 | 6480464 | Phlorhizin results in decreased expression of FMO1 mRNA | CTD | PMID:22538082 | phosgene | affects expression | ISO | RGD:10593 | 6480464 | Phosgene affects the expression of FMO1 mRNA | CTD | PMID:16300373 | piperonyl butoxide | decreases expression | EXP | | 6480464 | Piperonyl Butoxide results in decreased expression of FMO1 mRNA | CTD | PMID:22484513 | pirinixic acid | increases expression | ISO | RGD:10593 | 6480464 | pirinixic acid results in increased expression of FMO1 mRNA | CTD | PMID:15375163 more ... | pirinixic acid | increases expression | ISO | RGD:10593 | 6480464 | pirinixic acid results in increased expression of FMO1 mRNA | CTD | PMID:15375163 more ... | pirinixic acid | increases expression | ISO | RGD:10593 | 6480464 | pirinixic acid results in increased expression of FMO1 mRNA | CTD | PMID:18301758 more ... | pirinixic acid | increases expression | ISO | RGD:10593 | 6480464 | pirinixic acid results in increased expression of FMO1 mRNA | CTD | PMID:17426115 more ... | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of FMO1 mRNA | CTD | PMID:19162173 | pirinixic acid | affects expression | EXP | | 6480464 | pirinixic acid affects the expression of FMO1 mRNA | CTD | PMID:19483382 | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of FMO1 mRNA | CTD | PMID:19162173 | pyrimidin-2-amine | affects binding | EXP | | 6480464 | 2-aminopyrimidine analog binds to FMO1 protein | CTD | PMID:19317514 | quercetin | multiple interactions | ISO | RGD:736452 | 6480464 | [Quercetin co-treated with Ascorbic Acid] results in decreased expression of FMO1 mRNA | CTD | PMID:17639512 | rifampicin | multiple interactions | ISO | RGD:10593 | 6480464 | [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FMO1 mRNA | CTD | PMID:21224054 | rosiglitazone | multiple interactions | ISO | RGD:10593 | 6480464 | [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FMO1 mRNA | CTD | PMID:16054899 | rosiglitazone | decreases expression | EXP | | 6480464 | rosiglitazone results in decreased expression of FMO1 mRNA | CTD | PMID:21515302 | sodium chloride | increases expression | EXP | | 6480464 | Sodium Chloride results in increased expression of FMO1 protein; more ... | CTD | PMID:19429252 | sodium dichromate | decreases expression | ISO | RGD:10593 | 6480464 | sodium bichromate results in decreased expression of FMO1 mRNA | CTD | PMID:22155349 | tamoxifen | affects expression | ISO | RGD:10593 | 6480464 | Tamoxifen affects the expression of FMO1 mRNA | CTD | PMID:17555576 | tert-butyl hydroperoxide | decreases expression | ISO | RGD:736452 | 6480464 | tert-Butylhydroperoxide results in decreased expression of FMO1 mRNA | CTD | PMID:12419474 | testosterone | decreases expression | ISO | RGD:10593 | 6480464 | Testosterone results in decreased expression of FMO1 mRNA | CTD | PMID:21669218 PMID:20600201 | testosterone | decreases expression | ISO | RGD:10593 | 6480464 | Testosterone results in decreased expression of FMO1 mRNA | CTD | PMID:20600201 PMID:21669218 | tetrachloromethane | affects expression | EXP | | 6480464 | Carbon Tetrachloride affects the expression of FMO1 mRNA | CTD | PMID:12734012 PMID:15963342 | tetrachloromethane | affects expression | EXP | | 6480464 | Carbon Tetrachloride affects the expression of FMO1 mRNA | CTD | PMID:15963342 PMID:12734012 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of FMO1 protein | CTD | PMID:12629582 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of FMO1 mRNA | CTD | PMID:17522070 | tetracycline | decreases expression | EXP | | 6480464 | Tetracycline results in decreased expression of FMO1 mRNA | CTD | PMID:17522070 | thioacetamide | affects expression | EXP | | 6480464 | Thioacetamide affects the expression of FMO1 mRNA | CTD | PMID:19483382 | trimellitic anhydride | decreases expression | ISO | RGD:10593 | 6480464 | trimellitic anhydride results in decreased expression of FMO1 mRNA | CTD | PMID:19042947 | troglitazone | decreases expression | ISO | RGD:736452 | 6480464 | troglitazone results in decreased expression of FMO1 mRNA | CTD | PMID:19631733 | troglitazone | decreases expression | EXP | | 6480464 | troglitazone results in decreased expression of FMO1 mRNA | CTD | PMID:21515302 | troglitazone | increases expression | ISO | RGD:736452 | 6480464 | troglitazone results in increased expression of FMO1 mRNA | CTD | PMID:19631733 | tunicamycin | decreases expression | ISO | RGD:10593 | 6480464 | Tunicamycin results in decreased expression of FMO1 mRNA | CTD | PMID:17127020 | valproic acid | affects expression | ISO | RGD:10593 | 6480464 | Valproic Acid affects the expression of FMO1 mRNA | CTD | PMID:17963808 | zinc pyrithione | increases expression | ISO | RGD:736452 | 6480464 | zinc pyrithione results in increased expression of FMO1 mRNA | CTD | PMID:21424779 | |
Gene Ontology AnnotationsBiological Process









