Annotation (Toggle Detail/Summary View) Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2,4-trimethylbenzene | decreases expression | EXP | | 6480464 | pseudocumene results in decreased expression of ECH1 protein | CTD | PMID:17337753 | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of ECH1 mRNA | CTD | PMID:17351261 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of ECH1 mRNA | CTD | PMID:17108234 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:732279 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ECH1 mRNA | CTD | PMID:17035482 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ECH1 mRNA | CTD | PMID:16960034 more ... | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:732279 | 6480464 | Tetrachlorodibenzodioxin affects the expression of ECH1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ECH1 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ECH1 mRNA | CTD | PMID:16960034 PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ECH1 mRNA | CTD | PMID:15644576 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ECH1 mRNA | CTD | PMID:16960034 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of ECH1 mRNA | CTD | PMID:21346803 | 3,3',4,4'-tetrachlorobiphenyl | multiple interactions | ISO | RGD:732279 | 6480464 | 3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of ECH1 mRNA] | CTD | PMID:19467301 | 3,3',5-triiodo-L-thyronine | increases expression | EXP | | 6480464 | Triiodothyronine results in increased expression of ECH1 mRNA | CTD | PMID:15953391 | 3H-1,2-dithiole-3-thione | decreases expression | EXP | | 6480464 | 1,2-dithiol-3-thione results in decreased expression of ECH1 mRNA | CTD | PMID:19162173 | 4,4'-diaminodiphenylmethane | increases expression | ISO | RGD:732279 | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of ECH1 mRNA | CTD | PMID:18648102 | 7H-xanthine | multiple interactions | EXP | | 6480464 | [Xanthine co-treated with XDH protein] results in decreased expression of ECH1 protein | CTD | PMID:19464573 | 9H-xanthine | multiple interactions | EXP | | 6480464 | [Xanthine co-treated with XDH protein] results in decreased expression of ECH1 protein | CTD | PMID:19464573 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of ECH1 mRNA | CTD | PMID:16483693 | benzo[a]pyrene | multiple interactions | ISO | RGD:732279 | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of ECH1 mRNA] | CTD | PMID:22228805 | benzo[a]pyrene | increases expression | ISO | RGD:732279 | 6480464 | Benzo(a)pyrene results in increased expression of ECH1 mRNA | CTD | PMID:22228805 | bezafibrate | increases expression | ISO | RGD:732279 | 6480464 | Bezafibrate results in increased expression of ECH1 mRNA | CTD | PMID:17118139 | bis(2-ethylhexyl) phthalate | increases expression | ISO | RGD:732279 | 6480464 | Diethylhexyl Phthalate results in increased expression of ECH1 mRNA | CTD | PMID:19850644 | bis(2-ethylhexyl) phthalate | increases expression | EXP | | 6480464 | Diethylhexyl Phthalate results in increased expression of ECH1 mRNA | CTD | PMID:22672789 | bis(2-ethylhexyl) phthalate | increases expression | ISO | RGD:732279 | 6480464 | Diethylhexyl Phthalate results in increased expression of ECH1 mRNA | CTD | PMID:19245819 PMID:19850644 | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | RGD:732279 | 6480464 | PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of ECH1 mRNA] | CTD | PMID:19850644 | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of ECH1 protein | CTD | PMID:22081424 | choline | multiple interactions | ISO | RGD:732279 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ECH1 gene | CTD | PMID:20938992 | ciprofibrate | increases expression | EXP | | 6480464 | ciprofibrate results in increased expression of ECH1 protein | CTD | PMID:1740018 | cisplatin | increases expression | EXP | | 6480464 | Cisplatin results in increased expression of ECH1 protein | CTD | PMID:22023808 | clofibrate | multiple interactions | ISO | RGD:732279 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of ECH1 mRNA; more ... | CTD | PMID:17585979 | clofibrate | increases expression | EXP | | 6480464 | Clofibrate results in increased expression of ECH1 mRNA | CTD | PMID:12851107 | clofibrate | increases expression | EXP | | 6480464 | Clofibrate results in increased expression of ECH1 protein | CTD | PMID:16470657 PMID:1740018 | clofibrate | increases expression | EXP | | 6480464 | Clofibrate results in increased expression of ECH1 protein | CTD | PMID:1740018 PMID:16470657 | cobalt dichloride | decreases expression | ISO | RGD:732278 | 6480464 | cobaltous chloride results in decreased expression of ECH1 mRNA | CTD | PMID:19320972 | copper(2+) sulfate | decreases expression | ISO | RGD:732278 | 6480464 | Copper Sulfate results in decreased expression of ECH1 mRNA | CTD | PMID:19549813 | curcumin | increases expression | EXP | | 6480464 | Curcumin results in increased expression of ECH1 mRNA | CTD | PMID:18539377 | cyclosporin A | decreases expression | ISO | RGD:732278 | 6480464 | Cyclosporine results in decreased expression of ECH1 mRNA | CTD | PMID:20106945 | cyclosporin A | decreases expression | ISO | RGD:732279 | 6480464 | Cyclosporine results in decreased expression of ECH1 mRNA | CTD | PMID:19770486 | dasatinib (anhydrous) | increases expression | ISO | RGD:732278 | 6480464 | dasatinib results in increased expression of ECH1 mRNA | CTD | PMID:20579391 | diarsenic trioxide | increases expression | ISO | RGD:732278 | 6480464 | arsenic trioxide results in increased expression of ECH1 protein | CTD | PMID:19364129 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of ECH1 mRNA | CTD | PMID:21266533 | disodium selenite | increases expression | ISO | RGD:732278 | 6480464 | Sodium Selenite results in increased expression of ECH1 mRNA | CTD | PMID:18175754 | diuron | increases expression | EXP | | 6480464 | Diuron results in increased expression of ECH1 mRNA | CTD | PMID:21551480 | ethanol | multiple interactions | EXP | | 6480464 | [Fish Oils co-treated with Ethanol] results in increased expression of ECH1 mRNA | CTD | PMID:17347304 | fenofibrate | affects expression | EXP | | 6480464 | Fenofibrate affects the expression of ECH1 mRNA | CTD | PMID:20801182 | fenofibrate | increases expression | EXP | | 6480464 | Fenofibrate results in increased expression of ECH1 protein | CTD | PMID:20118634 | fenofibrate | increases expression | ISO | RGD:732279 | 6480464 | Fenofibrate results in increased expression of ECH1 mRNA | CTD | PMID:17118139 PMID:11798191 | fenofibrate | increases expression | ISO | RGD:732279 | 6480464 | Fenofibrate results in increased expression of ECH1 mRNA | CTD | PMID:11798191 PMID:17118139 | flutamide | decreases expression | ISO | RGD:732279 | 6480464 | Flutamide results in decreased expression of ECH1 mRNA | CTD | PMID:19442681 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of ECH1 protein | CTD | PMID:17311803 | folic acid | multiple interactions | ISO | RGD:732279 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ECH1 gene | CTD | PMID:20938992 | genistein | decreases expression | ISO | RGD:732278 | 6480464 | Genistein results in decreased expression of ECH1 mRNA | CTD | PMID:19371625 | gliotoxin | decreases expression | EXP | | 6480464 | Gliotoxin results in decreased expression of ECH1 mRNA | CTD | PMID:18346771 | hydroxyurea | increases mutagenesis | ISO | RGD:732279 | 6480464 | Hydroxyurea results in increased mutagenesis of ECH1 gene | CTD | PMID:16868089 | isotretinoin | decreases expression | ISO | RGD:732278 | 6480464 | Isotretinoin results in decreased expression of ECH1 mRNA | CTD | PMID:20436886 | L-methionine | multiple interactions | ISO | RGD:732279 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ECH1 gene | CTD | PMID:20938992 | lithium atom | increases expression | EXP | | 6480464 | Lithium results in increased expression of ECH1 protein | CTD | PMID:18296634 | methotrexate | increases expression | ISO | RGD:732278 | 6480464 | Methotrexate results in increased expression of ECH1 mRNA | CTD | PMID:17400583 | morphine | decreases expression | EXP | | 6480464 | Morphine results in decreased expression of ECH1 protein | CTD | PMID:23056601 | N-methyl-N-nitrosurea | increases mutagenesis | ISO | RGD:732279 | 6480464 | Methylnitrosourea results in increased mutagenesis of ECH1 gene | CTD | PMID:16868089 | nitric oxide | increases expression | ISO | RGD:732279 | 6480464 | Nitric Oxide deficiency results in increased expression of ECH1 mRNA | CTD | PMID:15878706 | paclitaxel | increases expression | EXP | | 6480464 | Paclitaxel results in increased expression of ECH1 mRNA | CTD | PMID:15585946 | paracetamol | multiple interactions | ISO | RGD:732279 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of ECH1 mRNA; more ... | CTD | PMID:17585979 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of ECH1 mRNA | CTD | PMID:18346771 | paracetamol | decreases expression | ISO | RGD:732279 | 6480464 | Acetaminophen results in decreased expression of ECH1 protein | CTD | PMID:11752693 | perfluorodecanoic acid | increases expression | EXP | | 6480464 | perfluorodecanoic acid results in increased expression of ECH1 protein | CTD | PMID:8160215 | perfluorooctane-1-sulfonic acid | affects expression | ISO | RGD:732279 | 6480464 | perfluorooctane sulfonic acid affects the expression of ECH1 mRNA | CTD | PMID:19429403 | perfluorooctane-1-sulfonic acid | increases expression | ISO | RGD:732279 | 6480464 | perfluorooctane sulfonic acid results in increased expression of ECH1 mRNA | CTD | PMID:20936131 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | RGD:732279 | 6480464 | PPARA protein promotes the reaction [perfluorooctane sulfonic acid results in increased expression of ECH1 mRNA] | CTD | PMID:20936131 | perfluorooctane-1-sulfonic acid | increases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in increased expression of ECH1 mRNA | CTD | PMID:19162173 more ... | perfluorooctane-1-sulfonic acid | increases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in increased expression of ECH1 mRNA | CTD | PMID:18692542 more ... | perfluorooctane-1-sulfonic acid | increases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in increased expression of ECH1 mRNA | CTD | PMID:16221955 more ... | perfluorooctane-1-sulfonic acid | increases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in increased expression of ECH1 mRNA | CTD | PMID:19162173 more ... | perfluorooctanoic acid | increases expression | ISO | RGD:732279 | 6480464 | perfluorooctanoic acid results in increased expression of ECH1 mRNA | CTD | PMID:18467677 PMID:17681415 | perfluorooctanoic acid | increases expression | ISO | RGD:732279 | 6480464 | perfluorooctanoic acid results in increased expression of ECH1 mRNA | CTD | PMID:17681415 more ... | perfluorooctanoic acid | multiple interactions | ISO | RGD:732279 | 6480464 | PPARA protein promotes the reaction [perfluorooctanoic acid results in increased expression of ECH1 mRNA] | CTD | PMID:20936131 | perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of ECH1 mRNA | CTD | PMID:16221955 PMID:19162173 | perfluorooctanoic acid | increases expression | ISO | RGD:732279 | 6480464 | perfluorooctanoic acid results in increased expression of ECH1 mRNA | CTD | PMID:17681415 PMID:18467677 | perfluorooctanoic acid | affects expression | ISO | RGD:732279 | 6480464 | perfluorooctanoic acid affects the expression of ECH1 mRNA | CTD | PMID:19429403 PMID:18281256 | perfluorooctanoic acid | affects expression | ISO | RGD:732279 | 6480464 | perfluorooctanoic acid affects the expression of ECH1 mRNA | CTD | PMID:18281256 PMID:19429403 | perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of ECH1 protein | CTD | PMID:8160215 | perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of ECH1 mRNA | CTD | PMID:19162173 PMID:16221955 | perfluorooctanoic acid | multiple interactions | ISO | RGD:732279 | 6480464 | PPARA protein affects the reaction [perfluorooctanoic acid results in increased expression of ECH1 mRNA] | CTD | PMID:18467677 | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of ECH1 mRNA | CTD | PMID:19162173 | piperonyl butoxide | increases expression | EXP | | 6480464 | Piperonyl Butoxide results in increased expression of ECH1 mRNA | CTD | PMID:22484513 | pirinixic acid | increases expression | ISO | RGD:732279 | 6480464 | pirinixic acid results in increased expression of ECH1 mRNA | CTD | PMID:20813756 more ... | pirinixic acid | increases expression | ISO | RGD:732279 | 6480464 | pirinixic acid results in increased expression of ECH1 mRNA | CTD | PMID:15375163 more ... | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of ECH1 mRNA | CTD | PMID:19162173 PMID:22484513 | pirinixic acid | multiple interactions | ISO | RGD:732279 | 6480464 | PPARA protein promotes the reaction [pirinixic acid results in increased expression of ECH1 mRNA] | CTD | PMID:17950772 more ... | pirinixic acid | increases expression | ISO | RGD:732279 | 6480464 | pirinixic acid results in increased expression of ECH1 mRNA | CTD | PMID:15375163 more ... | pirinixic acid | multiple interactions | ISO | RGD:732279 | 6480464 | PPARA protein promotes the reaction [pirinixic acid results in increased expression of ECH1 mRNA] | CTD | PMID:17950772 more ... | pirinixic acid | increases expression | ISO | RGD:732279 | 6480464 | pirinixic acid results in increased expression of ECH1 mRNA | CTD | PMID:15375163 more ... | pirinixic acid | increases expression | ISO | RGD:732279 | 6480464 | pirinixic acid results in increased expression of ECH1 mRNA | CTD | PMID:18301758 more ... | pirinixic acid | multiple interactions | ISO | RGD:732279 | 6480464 | PPARA protein promotes the reaction [pirinixic acid results in increased expression of ECH1 mRNA] | CTD | PMID:18467677 more ... | pirinixic acid | increases expression | ISO | RGD:732279 | 6480464 | pirinixic acid results in increased expression of ECH1 mRNA | CTD | PMID:17950772 more ... | pirinixic acid | increases expression | ISO | RGD:732279 | 6480464 | pirinixic acid results in increased expression of ECH1 mRNA | CTD | PMID:17426115 more ... | pirinixic acid | multiple interactions | ISO | RGD:732279 | 6480464 | PPARA protein promotes the reaction [pirinixic acid results in increased expression of ECH1 mRNA] | CTD | PMID:20059764 more ... | pirinixic acid | increases expression | ISO | RGD:732279 | 6480464 | pirinixic acid results in increased expression of ECH1 mRNA | CTD | PMID:16357043 more ... | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of ECH1 protein | CTD | PMID:1740018 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of ECH1 mRNA | CTD | PMID:19162173 | pirinixic acid | multiple interactions | ISO | RGD:732279 | 6480464 | PPARA protein promotes the reaction [pirinixic acid results in increased expression of ECH1 mRNA] | CTD | PMID:20059764 more ... | pirinixic acid | increases expression | ISO | RGD:732279 | 6480464 | pirinixic acid results in increased expression of ECH1 protein | CTD | PMID:12727805 | pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of ECH1 mRNA | CTD | PMID:19162173 | quercetin | increases expression | EXP | | 6480464 | Quercetin results in increased expression of ECH1 mRNA | CTD | PMID:17103110 | rosiglitazone | affects expression | ISO | RGD:732279 | 6480464 | rosiglitazone affects the expression of ECH1 mRNA | CTD | PMID:22013433 | rosiglitazone | increases expression | EXP | | 6480464 | rosiglitazone results in increased expression of ECH1 mRNA | CTD | PMID:21515302 | S-butyl-DL-homocysteine (S,R)-sulfoximine | increases expression | ISO | RGD:732279 | 6480464 | Buthionine Sulfoximine results in increased expression of ECH1 mRNA | CTD | PMID:15878706 | tert-butyl hydroperoxide | increases expression | ISO | RGD:732279 | 6480464 | tert-Butylhydroperoxide results in increased expression of ECH1 mRNA | CTD | PMID:15003993 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of ECH1 mRNA | CTD | PMID:18346771 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of ECH1 mRNA | CTD | PMID:19448997 | troglitazone | increases expression | EXP | | 6480464 | troglitazone results in increased expression of ECH1 mRNA | CTD | PMID:21515302 | troglitazone | increases expression | EXP | | 6480464 | troglitazone results in increased expression of ECH1 protein | CTD | PMID:21315101 | valproic acid | affects expression | ISO | RGD:732279 | 6480464 | Valproic Acid affects the expression of ECH1 mRNA | CTD | PMID:17963808 | zearalenone | decreases expression | ISO | RGD:732278 | 6480464 | Zearalenone results in decreased expression of ECH1 mRNA | CTD | PMID:19371625 | zinc atom | decreases expression | EXP | | 6480464 | Zinc deficiency results in decreased expression of ECH1 mRNA | CTD | PMID:12672911 PMID:15671213 | zinc(0) | decreases expression | EXP | | 6480464 | Zinc deficiency results in decreased expression of ECH1 mRNA | CTD | PMID:12672911 PMID:15671213 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology AnnotationsBiological Process





