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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2475
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2e1
Name: cytochrome P450, family 2, subfamily e, polypeptide 1
Acc ID: CHEBI:47105
Term: 1-bromopropane
Definition: A bromoalkane that is propane carrying a bromo substituent at position 1.
Chemical ID: MESH:C118559
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2e1increases expressionEXP 6480464CTD1-bromopropane results in increased expression of CYP2E1PMID:30247689
Cyp2e1multiple interactionsEXP 6480464CTDallyl sulfide inhibits the reaction [1-bromopropane results in increased expression of CYP2E1]PMID:30247689
Cyp2e1increases response to substanceISOCyp2e1 (Mus musculus)6480464CTDCYP2E1 protein results in increased susceptibility to 1-bromopropanePMID:19638432
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