Gene: Cyp27b1 (cytochrome P450, family 27, subfamily b, polypeptide 1) Rattus norvegicus
Symbol: Cyp27b1
Name: cytochrome P450, family 27, subfamily b, polypeptide 1
Description: ENCODES a protein that exhibits calcidiol 1-monooxygenase activity; INVOLVED IN aging; calcitriol biosynthetic process from calciol; lactation; PARTICIPATES IN Mycobacterium tuberculosis infection pathway; steroid biosynthetic pathway; ASSOCIATED WITH Acidosis; Acute Kidney Injury; Diabetes Mellitus, Experimental; FOUND IN mitochondrion; cytoplasm (ortholog); INTERACTS WITH 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine; bisphenol A; calcidiol
Type: protein-coding
Also known as: 25-hydroxyvitamin D(3) 1-alpha-hydroxylase; 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; 25-OHD-1 alpha-hydroxylase; calcidiol 1-monooxygenase; Cyp40; cytochrome p450 27B1; cytochrome P450 40 (25-hydroxyvitamin D3 1 alpha-hydroxylase); cytochrome P450 subfamily XXVIIB (25-hydroxyvitamin D-1-alpha-hydroxylase) polypeptide 1; cytochrome P450 subfamily XXVIIB polypeptide 1; cytochrome P450, 40 (25-hydroxyvitamin D3 1 alpha-hydroxylase); cytochrome P450, subfamily 27b, polypeptide 1; cytochrome P450, subfamily XXVIIB (25-hydroxyvitamin D-1-alpha-hydroxylase), polypeptide 1; cytochrome P450C1 alpha; cytochrome P450VD1-alpha; P450C1 alpha; P450VD1-alpha; VD3 1A hydroxylase
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.0770,333,150 - 70,340,006+NCBI
Rat Cytogenetic Map7  NCBI
RGSC Genome Assembly v5.0770,512,763 - 70,517,707+NCBI
Rat Celera Assembly760,014,507 - 60,019,451+NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cyp27b1
Entrez Gene
Ensembl Gene
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 69192
Created: 2001-11-13
Species: Rattus norvegicus
Last Modified: 2015-08-11
Status: ACTIVE