Gene: S1pr1 (sphingosine-1-phosphate receptor 1) Rattus norvegicus
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Symbol: S1pr1
Name: sphingosine-1-phosphate receptor 1
Description: ENCODES a protein that exhibits G-protein coupled receptor activity; sphingolipid binding; G-protein coupled receptor binding (ortholog); INVOLVED IN adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; endothelial cell differentiation; G-protein coupled receptor signaling pathway; PARTICIPATES IN G protein mediated signaling pathway via Galphai family; the extracellular signal-regulated Raf/Mek/Erk signaling pathway; platelet-derived growth factor signaling pathway; ASSOCIATED WITH cardiac hypertrophy; ASSOCIATED WITH Cardiomegaly; Carcinoma (ortholog); carcinoma (ortholog); FOUND IN external side of plasma membrane (ortholog); intracellular membrane-bounded organelle (ortholog); intrinsic component of plasma membrane (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Edg1; EDG1 (Edg1); endothelial differentiation G-protein coupled receptor 1; endothelial differentiation sphingolipid G-protein-coupled receptor 1; S1P receptor 1; S1P receptor Edg-1; S1P1; sphingosine 1-phosphate receptor 1; sphingosine 1-phosphate receptor Edg-1
Orthologs:
Homo sapiens (human) : S1PR1 (sphingosine-1-phosphate receptor 1)  HGNC
Mus musculus (house mouse) : S1pr1 (sphingosine-1-phosphate receptor 1)  MGI
Chinchilla lanigera (long-tailed chinchilla) : S1pr1 (sphingosine-1-phosphate receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : S1PR1 (sphingosine-1-phosphate receptor 1)
Canis lupus familiaris (dog) : S1PR1 (sphingosine-1-phosphate receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : S1pr1 (sphingosine-1-phosphate receptor 1)
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Is Marker For: Strains:   SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc   SHRSP.WKY-(D2Mit21-D2Rat157)/Gcrc  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02218,654,406 - 218,658,761 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.02236,742,193 - 236,746,400 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.42211,851,304 - 211,855,511 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12211,814,057 - 211,818,265 (-)NCBI
Celera2196,132,649 - 196,136,856 (-)NCBI
Cytogenetic Map2q41NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
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QTLs in Region (Rnor_6.0)
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Sequence

Nucleotide Sequences
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Transcriptome

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Strain Sequence Variants

Additional Information

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Nomenclature History
RGD Curation Notes
 
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RGD Object Information
RGD ID: 61958
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2017-05-30
Status: ACTIVE