Gene: Cyp7a1 (cytochrome P450, family 7, subfamily a, polypeptide 1)  Rattus norvegicus

Symbol: Cyp7a1
Name: cytochrome P450, family 7, subfamily a, polypeptide 1
Description: ENCODES a protein that exhibits cholesterol 7-alpha-monooxygenase activity; INVOLVED IN bile acid biosynthetic process; cellular response to cholesterol; cholesterol catabolic process; PARTICIPATES IN bile acid biosynthetic pathway; bile acid transport pathway; eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; FOUND IN intracellular membrane-bounded organelle; INTERACTS WITH (-)-epigallocatechin 3-gallate; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CHAP; cholesterol 7-alpha hydroxylase; cholesterol 7-alpha-hydroxylase; cholesterol 7-alpha-monooxygenase; CYP7; CYP7S1; CYPVII; Cytochrom P450 (cholesterol hydroxylase 7 alpha); cytochrome P450 (cholesterol hydroxylase 7 alpha); cytochrome P450, 7a1; cytochrome P450, family 7, subfamily a, polypeptide 1
Orthologs: Homo sapiens : CYP7A1 (cytochrome P450, family 7, subfamily A, polypeptide 1)  HGNC
Mus musculus : Cyp7a1 (cytochrome P450, family 7, subfamily a, polypeptide 1)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map5q12 NCBI
RGSC Genome Assembly v5.0524,143,589 - 24,153,286-NCBI
RGSC Genome Assembly v3.4519,707,159 - 19,716,856-NCBI
Rat Celera Assembly518,677,267 - 18,686,964-NCBI
Genome Assembly 3.1519,707,158 - 19,716,856-NCBI
Model

Launch Genome Browser (GBrowse)


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cyp7a1
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 2482
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE