Annotation (Toggle Detail/Summary View) Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | increases expression | EXP | | 6480464 | epigallocatechin gallate results in increased expression of CYP7A1 mRNA; more ... | CTD | PMID:23146761 | (24S)-24-hydroxycholesterol | increases metabolic processing | ISO | RGD:69210 | 6480464 | CYP7A1 protein results in increased metabolism of 24-hydroxycholesterol | CTD | PMID:11013305 | 1-naphthyl isothiocyanate | decreases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in decreased expression of CYP7A1 mRNA | CTD | PMID:14623915 | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of CYP7A1 mRNA | CTD | PMID:20551477 | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:10458 | 6480464 | ESR1 protein promotes the reaction [Ethinyl Estradiol results in decreased expression of CYP7A1 mRNA] | CTD | PMID:16606610 | 17alpha-ethynylestradiol | decreases activity | EXP | | 6480464 | Ethinyl Estradiol results in decreased activity of CYP7A1 protein | CTD | PMID:9869655 PMID:11473529 | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of CYP7A1 mRNA | CTD | PMID:9869655 more ... | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of CYP7A1 mRNA | CTD | PMID:9869655 more ... | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of CYP7A1 mRNA | CTD | PMID:17108234 more ... | 17alpha-ethynylestradiol | decreases activity | EXP | | 6480464 | Ethinyl Estradiol results in decreased activity of CYP7A1 protein | CTD | PMID:11473529 PMID:9869655 | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of CYP7A1 mRNA | CTD | PMID:16487557 more ... | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Ethinyl Estradiol co-treated with Diosgenin] results in increased expression of CYP7A1 mRNA | CTD | PMID:12963437 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | 3,6-dihydroxy-7-fluorocholanoic acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of CYP7A1 mRNA]; more ... | CTD | PMID:16487557 | 17alpha-ethynylestradiol | decreases expression | ISO | RGD:10458 | 6480464 | Ethinyl Estradiol results in decreased expression of CYP7A1 mRNA | CTD | PMID:16606610 | 17beta-estradiol | decreases expression | ISO | RGD:69210 | 6480464 | Estradiol results in decreased expression of CYP7A1 mRNA | CTD | PMID:20106945 | 1H-pyrazole | decreases expression | ISO | RGD:10458 | 6480464 | pyrazole results in decreased expression of CYP7A1 mRNA | CTD | PMID:17945193 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:69210 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CYP7A1 mRNA | CTD | PMID:20106945 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CYP7A1 mRNA | CTD | PMID:16054898 PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:10458 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CYP7A1 mRNA | CTD | PMID:19770486 PMID:21846477 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:10458 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CYP7A1 mRNA | CTD | PMID:21095216 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:10458 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CYP7A1 mRNA | CTD | PMID:19770486 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CYP7A1 mRNA | CTD | PMID:16054898 | 2,4,6-trinitrotoluene | affects expression | EXP | | 6480464 | Trinitrotoluene affects the expression of CYP7A1 mRNA | CTD | PMID:21346803 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of CYP7A1 mRNA | CTD | PMID:21346803 | 2-acetamidofluorene | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CYP7A1 mRNA | CTD | PMID:14656948 | 2-acetamidofluorene | multiple interactions | EXP | | 6480464 | [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of CYP7A1 mRNA | CTD | PMID:16158176 | 2-trans,6-trans,10-trans-geranylgeranyl diphosphate | multiple interactions | ISO | RGD:10458 | 6480464 | geranylgeranyl pyrophosphate inhibits the reaction [resveratrol results in increased expression of CYP7A1 mRNA] | CTD | PMID:22607622 | 20-hydroxycholesterol | increases metabolic processing | EXP | | 6480464 | CYP7A1 protein results in increased metabolism of 20-hydroxycholesterol | CTD | PMID:10882719 | 20-hydroxycholesterol | increases metabolic processing | ISO | RGD:69210 | 6480464 | CYP7A1 protein results in increased metabolism of 20-hydroxycholesterol | CTD | PMID:10882719 | 25-hydroxycholesterol | increases metabolic processing | ISO | RGD:69210 | 6480464 | CYP7A1 protein results in increased metabolism of 25-hydroxycholesterol | CTD | PMID:10882719 | 25-hydroxycholesterol | increases metabolic processing | EXP | | 6480464 | CYP7A1 protein results in increased metabolism of 25-hydroxycholesterol | CTD | PMID:10882719 | 26-hydroxycholesterol | increases metabolic processing | ISO | RGD:69210 | 6480464 | CYP7A1 protein results in increased metabolism of 27-hydroxycholesterol | CTD | PMID:10882719 | 26-hydroxycholesterol | increases metabolic processing | EXP | | 6480464 | CYP7A1 protein results in increased metabolism of 27-hydroxycholesterol | CTD | PMID:10882719 | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | ISO | RGD:69210 | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP7A1 mRNA | CTD | PMID:23146750 | 3,3',4,4'-tetrachlorobiphenyl | multiple interactions | ISO | RGD:10458 | 6480464 | 3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of CYP7A1 mRNA] | CTD | PMID:19467301 | 7alpha-hydroxycholesterol | multiple interactions | EXP | | 6480464 | [Uranyl Nitrate results in decreased activity of CYP7A1 protein] which results in decreased chemical synthesis of cholest-5-en-3 beta,7 alpha-diol | CTD | PMID:20362056 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of CYP7A1 mRNA | CTD | PMID:15749267 | aflatoxin B1 | affects expression | ISO | RGD:69210 | 6480464 | Aflatoxin B1 affects the expression of CYP7A1 protein | CTD | PMID:20106945 | aflatoxin B1 | decreases expression | ISO | RGD:69210 | 6480464 | Aflatoxin B1 results in decreased expression of CYP7A1 mRNA | CTD | PMID:22100608 | aflatoxin B1 | decreases expression | ISO | RGD:10458 | 6480464 | Aflatoxin B1 results in decreased expression of CYP7A1 mRNA | CTD | PMID:19770486 | all-trans-retinoic acid | multiple interactions | ISO | RGD:69210 | 6480464 | Tretinoin promotes the reaction [Ursodeoxycholic Acid results in decreased expression of CYP7A1 mRNA]; more ... | CTD | PMID:21274875 | all-trans-retinoic acid | multiple interactions | EXP | | 6480464 | [Tretinoin co-treated with Ursodeoxycholic Acid] results in decreased expression of CYP7A1 mRNA | CTD | PMID:21274875 | all-trans-retinoic acid | decreases expression | ISO | RGD:69210 | 6480464 | Tretinoin results in decreased expression of CYP7A1 mRNA | CTD | PMID:21274875 | amiodarone | decreases expression | EXP | | 6480464 | Amiodarone results in decreased expression of CYP7A1 mRNA | CTD | PMID:19224547 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of CYP7A1 mRNA | CTD | PMID:16483693 | arsenic atom | multiple interactions | ISO | RGD:10458 | 6480464 | [APOE protein affects the susceptibility to Arsenic] which affects the expression of CYP7A1 mRNA | CTD | PMID:22719926 | atrazine | increases expression | ISO | RGD:10458 | 6480464 | Atrazine results in increased expression of CYP7A1 mRNA | CTD | PMID:22515965 | benzo[a]pyrene | multiple interactions | ISO | RGD:10458 | 6480464 | [Benzo(a)pyrene co-treated with XPA gene mutant form co-treated with TRP53 gene mutant form] results in decreased expression of CYP7A1 mRNA | CTD | PMID:21715664 | benzo[a]pyrene | affects expression | EXP | | 6480464 | Benzo(a)pyrene affects the expression of CYP7A1 mRNA | CTD | PMID:22374506 | benzo[a]pyrene | decreases expression | ISO | RGD:10458 | 6480464 | Benzo(a)pyrene results in decreased expression of CYP7A1 mRNA | CTD | PMID:19770486 | bezafibrate | increases expression | ISO | RGD:69210 | 6480464 | Bezafibrate results in increased expression of CYP7A1 mRNA | CTD | PMID:14685799 | bezafibrate | decreases activity | EXP | | 6480464 | Bezafibrate results in decreased activity of CYP7A1 protein | CTD | PMID:2044640 | bezafibrate | decreases expression | ISO | RGD:69210 | 6480464 | Bezafibrate results in decreased expression of CYP7A1 mRNA | CTD | PMID:14685799 | bezafibrate | decreases activity | ISO | RGD:69210 | 6480464 | Bezafibrate results in decreased activity of CYP7A1 protein | CTD | PMID:2044640 | bilirubin | multiple interactions | EXP | | 6480464 | [Manganese co-treated with Bilirubin] results in decreased activity of CYP7A1 protein | CTD | PMID:12700418 | bilirubin | decreases activity | EXP | | 6480464 | Bilirubin results in decreased activity of CYP7A1 protein | CTD | PMID:12700418 | bis(2-ethylhexyl) phthalate | increases expression | ISO | RGD:10458 | 6480464 | Diethylhexyl Phthalate results in increased expression of CYP7A1 mRNA | CTD | PMID:19850644 | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | RGD:10458 | 6480464 | PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of CYP7A1 mRNA] | CTD | PMID:19850644 | bisphenol A | increases expression | ISO | RGD:10458 | 6480464 | bisphenol A results in increased expression of CYP7A1 mRNA | CTD | PMID:17706920 | bisphenol A | decreases expression | ISO | RGD:69210 | 6480464 | bisphenol A results in decreased expression of CYP7A1 mRNA | CTD | PMID:23146750 | bisphenol A | multiple interactions | ISO | RGD:10458 | 6480464 | LHB protein affects the reaction [bisphenol A results in increased expression of CYP7A1 mRNA] | CTD | PMID:17706920 | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of CYP7A1 promoter | CTD | PMID:22457795 | chenodeoxycholic acid | decreases expression | ISO | RGD:69210 | 6480464 | Chenodeoxycholic Acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:19072826 | chenodeoxycholic acid | multiple interactions | EXP | | 6480464 | [Chenodeoxycholic Acid results in increased expression of FGF19 protein] which results in decreased expression of CYP7A1 protein | CTD | PMID:20835427 | chenodeoxycholic acid | decreases expression | ISO | RGD:10458 | 6480464 | Chenodeoxycholic Acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:19072826 PMID:20671298 | chenodeoxycholic acid | multiple interactions | ISO | RGD:10458 | 6480464 | NR1H4 mutant form inhibits the reaction [Chenodeoxycholic Acid results in decreased expression of CYP7A1 mRNA] | CTD | PMID:19072826 | chenodeoxycholic acid | decreases expression | ISO | RGD:10458 | 6480464 | Chenodeoxycholic Acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:19072826 | cholesterol | affects metabolic processing | ISO | RGD:69210 | 6480464 | CYP7A1 protein affects the metabolism of Cholesterol | CTD | PMID:15696852 | cholesterol | increases expression | EXP | | 6480464 | Cholesterol results in increased expression of CYP7A1 mRNA | CTD | PMID:21535835 | cholesterol | multiple interactions | EXP | | 6480464 | turmeric extract promotes the reaction [Cholesterol results in increased expression of CYP7A1 mRNA] | CTD | PMID:21535835 | cholesterol | increases metabolic processing | ISO | RGD:69210 | 6480464 | CYP7A1 protein results in increased metabolism of Cholesterol | CTD | PMID:7925343 PMID:11013305 | cholesterol | increases metabolic processing | ISO | RGD:69210 | 6480464 | CYP7A1 protein results in increased metabolism of Cholesterol | CTD | PMID:11013305 PMID:7925343 | cholic acid | decreases expression | ISO | RGD:10458 | 6480464 | Cholic Acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:17521389 more ... | cholic acid | decreases expression | ISO | RGD:10458 | 6480464 | Cholic Acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:12072388 more ... | cholic acid | decreases expression | ISO | RGD:10458 | 6480464 | Cholic Acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:17521389 more ... | cholic acid | decreases expression | ISO | RGD:10458 | 6480464 | Cholic Acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:12072388 more ... | cholic acid | multiple interactions | EXP | | 6480464 | [Cholesterol, Dietary co-treated with Cholic Acid] results in decreased activity of CYP7A1 protein; more ... | CTD | PMID:14684380 | cholic acid | decreases expression | ISO | RGD:10458 | 6480464 | Cholic Acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:12072388 more ... | ciguatoxin CTX1B | affects expression | ISO | RGD:10458 | 6480464 | Ciguatoxins affects the expression of CYP7A1 mRNA | CTD | PMID:18353800 | clofibrate | decreases expression | ISO | RGD:10458 | 6480464 | Clofibrate results in decreased expression of CYP7A1 mRNA | CTD | PMID:17585979 | clofibrate | decreases expression | EXP | | 6480464 | Clofibrate results in decreased expression of CYP7A1 mRNA | CTD | PMID:19224547 | cobalt atom | increases expression | ISO | RGD:10458 | 6480464 | Cobalt results in increased expression of CYP7A1 mRNA | CTD | PMID:22147119 | copper atom | decreases expression | ISO | RGD:10458 | 6480464 | Copper results in decreased expression of CYP7A1 mRNA | CTD | PMID:17205981 | copper atom | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of CYP7A1 mRNA | CTD | PMID:11110846 | copper(0) | decreases expression | ISO | RGD:10458 | 6480464 | Copper results in decreased expression of CYP7A1 mRNA | CTD | PMID:17205981 | copper(0) | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of CYP7A1 mRNA | CTD | PMID:11110846 | copper(2+) sulfate | decreases expression | ISO | RGD:69210 | 6480464 | Copper Sulfate results in decreased expression of CYP7A1 mRNA | CTD | PMID:19549813 | coumarin | decreases expression | EXP | | 6480464 | coumarin results in decreased expression of CYP7A1 mRNA | CTD | PMID:18480146 | cyclosporin A | decreases expression | ISO | RGD:69210 | 6480464 | Cyclosporine results in decreased expression of CYP7A1 mRNA | CTD | PMID:20106945 | cyclosporin A | increases expression | ISO | RGD:10458 | 6480464 | Cyclosporine results in increased expression of CYP7A1 mRNA | CTD | PMID:19770486 | deoxycholic acid | decreases expression | ISO | RGD:69210 | 6480464 | Deoxycholic Acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:14684751 | deoxycholic acid | decreases expression | ISO | RGD:10458 | 6480464 | Deoxycholic Acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:20671298 PMID:21914718 | deoxycholic acid | decreases expression | ISO | RGD:10458 | 6480464 | Deoxycholic Acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:21914718 | deoxycholic acid | multiple interactions | ISO | RGD:10458 | 6480464 | SLCO1A1 protein affects the susceptibility to [Deoxycholic Acid results in decreased expression of CYP7A1 mRNA] | CTD | PMID:21914718 | dexamethasone | increases expression | EXP | | 6480464 | Dexamethasone results in increased expression of CYP7A1 mRNA | CTD | PMID:15965953 | dexamethasone | decreases expression | EXP | | 6480464 | Dexamethasone results in decreased expression of CYP7A1 mRNA | CTD | PMID:20888898 | dioxygen | decreases expression | ISO | RGD:69210 | 6480464 | Oxygen deficiency results in decreased expression of CYP7A1 mRNA | CTD | PMID:19695866 | ethanol | multiple interactions | EXP | | 6480464 | [Fish Oils co-treated with Ethanol] results in increased expression of CYP7A1 mRNA | CTD | PMID:17347304 | ethanol | increases expression | ISO | RGD:10458 | 6480464 | Ethanol results in increased expression of CYP7A1 mRNA | CTD | PMID:19167417 | fenofibrate | increases expression | ISO | RGD:69210 | 6480464 | Fenofibrate results in increased expression of CYP7A1 mRNA | CTD | PMID:14685799 | fenofibrate | decreases expression | ISO | RGD:69210 | 6480464 | Fenofibrate results in decreased expression of CYP7A1 mRNA | CTD | PMID:14685799 | fenofibrate | multiple interactions | EXP | | 6480464 | [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP7A1 mRNA | CTD | PMID:18253720 | furan | decreases expression | EXP | | 6480464 | furan results in decreased expression of CYP7A1 mRNA | CTD | PMID:15120968 | gemfibrozil | increases expression | ISO | RGD:69210 | 6480464 | Gemfibrozil results in increased expression of CYP7A1 mRNA | CTD | PMID:14685799 | gemfibrozil | decreases expression | ISO | RGD:69210 | 6480464 | Gemfibrozil results in decreased expression of CYP7A1 mRNA | CTD | PMID:14685799 | glycyrrhizinic acid | decreases expression | ISO | RGD:10458 | 6480464 | Glycyrrhizic Acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:22982774 | kojic acid | multiple interactions | ISO | RGD:10458 | 6480464 | [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CYP7A1 mRNA; more ... | CTD | PMID:17917374 | L-ascorbic acid | multiple interactions | ISO | RGD:10458 | 6480464 | [Diethylnitrosamine co-treated with Ascorbic Acid] results in increased expression of CYP7A1 mRNA; more ... | CTD | PMID:17917374 | lead(0) | multiple interactions | EXP | | 6480464 | puerarin affects the reaction [Lead affects the expression of CYP7A1] | CTD | PMID:22001170 | lead(0) | affects expression | EXP | | 6480464 | Lead affects the expression of CYP7A1 | CTD | PMID:22001170 | lithocholic acid | decreases expression | EXP | | 6480464 | Lithocholic Acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:20888898 | lithocholic acid | decreases expression | ISO | RGD:10458 | 6480464 | Lithocholic Acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:20359477 more ... | lithocholic acid | decreases expression | ISO | RGD:10458 | 6480464 | Lithocholic Acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:20359477 PMID:22982774 | lithocholic acid | multiple interactions | ISO | RGD:10458 | 6480464 | Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of CYP7A1 mRNA] | CTD | PMID:20359477 | lithocholic acid | decreases expression | ISO | RGD:10458 | 6480464 | Lithocholic Acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:20359477 | manganese atom | multiple interactions | EXP | | 6480464 | [Manganese co-treated with Bilirubin] results in decreased activity of CYP7A1 protein | CTD | PMID:12700418 | manganese atom | increases activity | EXP | | 6480464 | Manganese results in increased activity of CYP7A1 protein | CTD | PMID:12700418 | manganese(0) | multiple interactions | EXP | | 6480464 | [Manganese co-treated with Bilirubin] results in decreased activity of CYP7A1 protein | CTD | PMID:12700418 | manganese(0) | increases activity | EXP | | 6480464 | Manganese results in increased activity of CYP7A1 protein | CTD | PMID:12700418 | methotrexate | decreases expression | EXP | | 6480464 | Methotrexate results in decreased expression of CYP7A1 mRNA | CTD | PMID:15120968 | monocrotaline | multiple interactions | ISO | RGD:10458 | 6480464 | [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP7A1 mRNA | CTD | PMID:21224054 | N-nitrosodiethylamine | multiple interactions | ISO | RGD:10458 | 6480464 | [Diethylnitrosamine co-treated with Ascorbic Acid] results in increased expression of CYP7A1 mRNA; more ... | CTD | PMID:17917374 | N-nitrosodiethylamine | decreases expression | EXP | | 6480464 | Diethylnitrosamine results in decreased expression of CYP7A1 mRNA | CTD | PMID:19638242 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP7A1 mRNA | CTD | PMID:18253720 | N-nitrosodiethylamine | increases expression | ISO | RGD:10458 | 6480464 | Diethylnitrosamine results in increased expression of CYP7A1 mRNA | CTD | PMID:18691550 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CYP7A1 mRNA | CTD | PMID:14656948 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of CYP7A1 mRNA | CTD | PMID:16158176 | N-nitrosodiethylamine | multiple interactions | ISO | RGD:10458 | 6480464 | IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased expression of CYP7A1 mRNA] | CTD | PMID:18691550 | nickel atom | increases expression | ISO | RGD:10458 | 6480464 | Nickel results in increased expression of CYP7A1 mRNA | CTD | PMID:18922574 | paclitaxel | decreases expression | EXP | | 6480464 | Paclitaxel results in decreased expression of CYP7A1 mRNA | CTD | PMID:15585946 | paracetamol | affects expression | ISO | RGD:10458 | 6480464 | Acetaminophen affects the expression of CYP7A1 mRNA | CTD | PMID:15030884 PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of CYP7A1 mRNA | CTD | PMID:15120968 PMID:17202762 | paracetamol | decreases expression | ISO | RGD:10458 | 6480464 | Acetaminophen results in decreased expression of CYP7A1 mRNA | CTD | PMID:18544908 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of CYP7A1 mRNA | CTD | PMID:17202762 PMID:15120968 | paracetamol | affects expression | ISO | RGD:10458 | 6480464 | Acetaminophen affects the expression of CYP7A1 mRNA | CTD | PMID:17562736 PMID:15030884 | perfluorobutyric acid | increases expression | EXP | | 6480464 | perfluorobutyric acid analog results in increased expression of CYP7A1 mRNA | CTD | PMID:21878386 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | RGD:10458 | 6480464 | perfluorooctane sulfonic acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:19429403 PMID:21705711 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | RGD:10458 | 6480464 | PPARA protein promotes the reaction [perfluorooctane sulfonic acid results in decreased expression of CYP7A1 mRNA] | CTD | PMID:20936131 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | RGD:10458 | 6480464 | perfluorooctane sulfonic acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:19429403 more ... | perfluorooctane-1-sulfonic acid | decreases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:16221955 more ... | perfluorooctane-1-sulfonic acid | decreases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:16221955 more ... | perfluorooctane-1-sulfonic acid | decreases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:18692542 more ... | perfluorooctane-1-sulfonic acid | decreases expression | ISO | RGD:10458 | 6480464 | perfluorooctane sulfonic acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:21705711 PMID:19429403 | perfluorooctane-1-sulfonic acid | decreases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:19429409 more ... | perfluorooctanoic acid | decreases expression | ISO | RGD:10458 | 6480464 | perfluorooctanoic acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:19429403 PMID:17681415 | perfluorooctanoic acid | decreases expression | ISO | RGD:10458 | 6480464 | perfluorooctanoic acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:17681415 more ... | perfluorooctanoic acid | multiple interactions | ISO | RGD:10458 | 6480464 | PPARA protein promotes the reaction [perfluorooctanoic acid results in decreased expression of CYP7A1 mRNA] | CTD | PMID:20936131 | perfluorooctanoic acid | decreases expression | ISO | RGD:10458 | 6480464 | perfluorooctanoic acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:17681415 PMID:19429403 | phenobarbital | affects expression | ISO | RGD:69210 | 6480464 | Phenobarbital affects the expression of CYP7A1 mRNA | CTD | PMID:15629111 | phenobarbital | decreases expression | EXP | | 6480464 | Phenobarbital results in decreased expression of CYP7A1 mRNA | CTD | PMID:19162173 | phenobarbital | decreases expression | ISO | RGD:10458 | 6480464 | Phenobarbital results in decreased expression of CYP7A1 mRNA | CTD | PMID:15629111 | phenobarbital | increases expression | ISO | RGD:10458 | 6480464 | Phenobarbital results in increased expression of CYP7A1 mRNA | CTD | PMID:19270015 | phenytoin | multiple interactions | ISO | RGD:10458 | 6480464 | [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP7A1 mRNA | CTD | PMID:21224054 | phorbol 13-acetate 12-myristate | multiple interactions | ISO | RGD:69210 | 6480464 | [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CYP7A1 mRNA | CTD | PMID:16979875 | pioglitazone | multiple interactions | ISO | RGD:10458 | 6480464 | U 0126 promotes the reaction [pioglitazone results in increased expression of CYP7A1 mRNA]; more ... | CTD | PMID:22593575 | pioglitazone | increases expression | ISO | RGD:10458 | 6480464 | pioglitazone results in increased expression of CYP7A1 mRNA | CTD | PMID:22593575 | pirinixic acid | decreases expression | ISO | RGD:10458 | 6480464 | pirinixic acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:18445702 more ... | pirinixic acid | multiple interactions | ISO | RGD:10458 | 6480464 | PPARA protein promotes the reaction [pirinixic acid results in decreased expression of CYP7A1 mRNA] | CTD | PMID:20059764 PMID:20936131 | pirinixic acid | increases expression | ISO | RGD:10458 | 6480464 | pirinixic acid results in increased expression of CYP7A1 mRNA | CTD | PMID:20936131 | pirinixic acid | decreases expression | ISO | RGD:10458 | 6480464 | pirinixic acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:15777286 more ... | pirinixic acid | decreases expression | ISO | RGD:10458 | 6480464 | pirinixic acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:15777286 more ... | pirinixic acid | decreases expression | ISO | RGD:10458 | 6480464 | pirinixic acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:20059764 more ... | pirinixic acid | decreases expression | ISO | RGD:10458 | 6480464 | pirinixic acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:18445702 more ... | pirinixic acid | multiple interactions | ISO | RGD:10458 | 6480464 | PPARA protein promotes the reaction [pirinixic acid results in decreased expression of CYP7A1 mRNA] | CTD | PMID:20059764 | pirinixic acid | multiple interactions | ISO | RGD:10458 | 6480464 | PPARA protein affects the reaction [pirinixic acid results in decreased expression of CYP7A1 mRNA] | CTD | PMID:15777286 | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | RGD:10458 | 6480464 | Pregnenolone Carbonitrile results in decreased expression of CYP7A1 mRNA | CTD | PMID:15629111 | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | RGD:10458 | 6480464 | Pregnenolone Carbonitrile results in decreased expression of CYP7A1 mRNA | CTD | PMID:15629111 PMID:22982774 | pregnenolone 16alpha-carbonitrile | multiple interactions | ISO | RGD:10458 | 6480464 | Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of CYP7A1 mRNA] | CTD | PMID:20359477 | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of CYP7A1 mRNA | CTD | PMID:19162173 | propiconazole | increases expression | ISO | RGD:10458 | 6480464 | propiconazole results in increased expression of CYP7A1 mRNA | CTD | PMID:21278054 | resveratrol | increases expression | ISO | RGD:10458 | 6480464 | resveratrol results in increased expression of CYP7A1 mRNA | CTD | PMID:22607622 | resveratrol | multiple interactions | ISO | RGD:10458 | 6480464 | geranylgeranyl pyrophosphate inhibits the reaction [resveratrol results in increased expression of CYP7A1 mRNA]; more ... | CTD | PMID:22607622 | rifampicin | decreases expression | ISO | RGD:69210 | 6480464 | Rifampin results in decreased expression of CYP7A1 mRNA | CTD | PMID:15629111 | rifampicin | decreases expression | ISO | RGD:69210 | 6480464 | Rifampin results in decreased expression of CYP7A1 mRNA | CTD | PMID:15629111 PMID:21127053 | rifampicin | multiple interactions | ISO | RGD:69210 | 6480464 | NR1I2 protein promotes the reaction [Rifampin results in decreased expression of CYP7A1 mRNA] | CTD | PMID:21127053 | rifampicin | multiple interactions | ISO | RGD:10458 | 6480464 | [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP7A1 mRNA | CTD | PMID:21224054 | rosiglitazone | increases expression | EXP | | 6480464 | rosiglitazone results in increased expression of CYP7A1 mRNA | CTD | PMID:21515302 | sevoflurane | affects expression | EXP | | 6480464 | sevoflurane affects the expression of CYP7A1 mRNA | CTD | PMID:15967596 | spironolactone | decreases activity | EXP | | 6480464 | Spironolactone results in decreased activity of CYP7A1 protein | CTD | PMID:15652244 | streptozocin | increases expression | EXP | | 6480464 | Streptozocin results in increased expression of CYP7A1 mRNA | CTD | PMID:10393316 | tamoxifen | decreases expression | EXP | | 6480464 | Tamoxifen results in decreased expression of CYP7A1 mRNA | CTD | PMID:19224547 | tamoxifen | affects expression | ISO | RGD:10458 | 6480464 | Tamoxifen affects the expression of CYP7A1 mRNA | CTD | PMID:20937368 | taurocholic acid | multiple interactions | ISO | RGD:10458 | 6480464 | NR1H4 protein affects the reaction [Taurocholic Acid results in decreased expression of CYP7A1 mRNA]; more ... | CTD | PMID:16284190 | taurocholic acid | decreases expression | ISO | RGD:10458 | 6480464 | Taurocholic Acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:16284190 | testosterone | decreases expression | ISO | RGD:10458 | 6480464 | Testosterone results in decreased expression of CYP7A1 mRNA | CTD | PMID:21669218 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of CYP7A1 mRNA | CTD | PMID:19224547 | tetracycline | increases expression | ISO | RGD:10458 | 6480464 | Tetracycline results in increased expression of CYP7A1 mRNA | CTD | PMID:16917069 | tetracycline | decreases expression | EXP | | 6480464 | Tetracycline results in decreased expression of CYP7A1 mRNA | CTD | PMID:19224547 | toluene | affects expression | EXP | | 6480464 | Toluene affects the expression of CYP7A1 mRNA | CTD | PMID:18653662 | trans-resveratrol | multiple interactions | ISO | RGD:10458 | 6480464 | geranylgeranyl pyrophosphate inhibits the reaction [resveratrol results in increased expression of CYP7A1 mRNA]; more ... | CTD | PMID:22607622 | trans-resveratrol | increases expression | ISO | RGD:10458 | 6480464 | resveratrol results in increased expression of CYP7A1 mRNA | CTD | PMID:22607622 | trichloroethene | increases expression | ISO | RGD:10458 | 6480464 | Trichloroethylene results in increased expression of CYP7A1 mRNA | CTD | PMID:19254012 | troglitazone | decreases expression | ISO | RGD:69210 | 6480464 | troglitazone results in decreased expression of CYP7A1 mRNA | CTD | PMID:19631733 | troglitazone | increases expression | EXP | | 6480464 | troglitazone results in increased expression of CYP7A1 mRNA | CTD | PMID:21515302 | ursodeoxycholic acid | decreases expression | ISO | RGD:69210 | 6480464 | Ursodeoxycholic Acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:14684751 | ursodeoxycholic acid | decreases expression | ISO | RGD:10458 | 6480464 | Ursodeoxycholic Acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:20671298 | ursodeoxycholic acid | decreases expression | ISO | RGD:69210 | 6480464 | Ursodeoxycholic Acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:14684751 PMID:21274875 | ursodeoxycholic acid | increases expression | EXP | | 6480464 | Ursodeoxycholic Acid results in increased expression of CYP7A1 mRNA | CTD | PMID:16764892 | ursodeoxycholic acid | multiple interactions | EXP | | 6480464 | [Tretinoin co-treated with Ursodeoxycholic Acid] results in decreased expression of CYP7A1 mRNA | CTD | PMID:21274875 | ursodeoxycholic acid | decreases expression | ISO | RGD:69210 | 6480464 | Ursodeoxycholic Acid results in decreased expression of CYP7A1 mRNA | CTD | PMID:21274875 PMID:14684751 | ursodeoxycholic acid | multiple interactions | ISO | RGD:69210 | 6480464 | Tretinoin promotes the reaction [Ursodeoxycholic Acid results in decreased expression of CYP7A1 mRNA]; more ... | CTD | PMID:21274875 | ursodeoxycholic acid | affects expression | EXP | | 6480464 | Ursodeoxycholic Acid affects the expression of CYP7A1 mRNA | CTD | PMID:15452192 | ursodeoxycholic acid | multiple interactions | EXP | | 6480464 | Ursodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of CYP7A1 mRNA] | CTD | PMID:16487557 | zinc atom | multiple interactions | ISO | RGD:69210 | 6480464 | [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CYP7A1 mRNA | CTD | PMID:16979875 | zinc atom | increases expression | ISO | RGD:69210 | 6480464 | Zinc deficiency results in increased expression of CYP7A1 mRNA | CTD | PMID:18356318 | zinc pyrithione | increases expression | ISO | RGD:69210 | 6480464 | zinc pyrithione results in increased expression of CYP7A1 mRNA | CTD | PMID:21424779 | zinc(0) | multiple interactions | ISO | RGD:69210 | 6480464 | [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CYP7A1 mRNA | CTD | PMID:16979875 | zinc(0) | increases expression | ISO | RGD:69210 | 6480464 | Zinc deficiency results in increased expression of CYP7A1 mRNA | CTD | PMID:18356318 | |
Gene Ontology AnnotationsBiological Process











