(+)-isolariciresinol decreases expression ISO LDLR (Homo sapiens) 6480464 isolariciresinol results in decreased expression of LDLR protein CTD PMID:35755389 (-)-epigallocatechin 3-gallate increases expression ISO LDLR (Homo sapiens) 6480464 epigallocatechin gallate results in increased expression of LDLR mRNA CTD PMID:22079256 (-)-epigallocatechin 3-gallate multiple interactions ISO LDLR (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of LDLR mRNA CTD PMID:22079256 (-)-trans-epsilon-viniferin increases expression ISO LDLR (Homo sapiens) 6480464 epsilon-viniferin results in increased expression of LDLR mRNA CTD PMID:22153697 (1->4)-beta-D-glucan multiple interactions ISO Ldlr (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of LDLR mRNA CTD PMID:36331819 (25R)-cholest-5-ene-3beta,26-diol decreases activity ISO LDLR (Homo sapiens) 6480464 27-hydroxycholesterol results in decreased activity of LDLR protein CTD PMID:8820113 (25R)-cholest-5-ene-3beta,26-diol decreases expression EXP 6480464 27-hydroxycholesterol results in decreased expression of LDLR mRNA and 27-hydroxycholesterol results in decreased expression of LDLR protein CTD PMID:28167099 (2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonylamino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic acid multiple interactions ISO Ldlr (Mus musculus) 6480464 argatroban inhibits the reaction [[LDLR gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of Cholesterol] and argatroban inhibits the reaction [[LDLR gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of Triglycerides] CTD PMID:22841818 (S)-nicotine increases expression ISO LDLR (Homo sapiens) 6480464 Nicotine results in increased expression of LDLR mRNA CTD PMID:23416264 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane decreases expression ISO LDLR (Homo sapiens) 6480464 o and p'-DDT results in decreased expression of LDLR mRNA CTD PMID:18204070 1,2-dimethylhydrazine affects expression ISO Ldlr (Mus musculus) 6480464 1 and 2-Dimethylhydrazine affects the expression of LDLR mRNA CTD PMID:22206623 1,2-dimethylhydrazine multiple interactions ISO Ldlr (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of LDLR mRNA CTD PMID:22206623 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine increases expression EXP 6480464 chlorcyclizine results in increased expression of LDLR mRNA CTD PMID:21058326 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of LDLR mRNA CTD PMID:30723492 11-dehydro-thromboxane B2 multiple interactions ISO LDLR (Homo sapiens) 6480464 Aspirin inhibits the reaction [LDLR gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]] more ... CTD PMID:20530721 17alpha-ethynylestradiol multiple interactions ISO LDLR (Homo sapiens) 6480464 [Desogestrel co-treated with Ethinyl Estradiol] results in increased expression of LDLR protein and [Levonorgestrel co-treated with Ethinyl Estradiol] results in decreased expression of LDLR protein CTD PMID:17900441 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of LDLR mRNA and Ethinyl Estradiol results in increased expression of LDLR protein CTD PMID:12475377 more ... 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of LDLR mRNA CTD PMID:17351261 17alpha-ethynylestradiol increases expression ISO LDLR (Homo sapiens) 6480464 Ethinyl Estradiol results in increased expression of LDLR protein CTD PMID:17900441 17beta-estradiol increases expression ISO LDLR (Homo sapiens) 6480464 Estradiol results in increased expression of LDLR mRNA CTD PMID:19167446 and PMID:32387340 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of LDLR mRNA CTD PMID:32145629 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one affects localization ISO LDLR (Homo sapiens) 6480464 Metribolone affects the localization of LDLR protein CTD PMID:17440980 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO LDLR (Homo sapiens) 6480464 Dihydrotestosterone results in increased expression of LDLR mRNA CTD PMID:29581250 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO LDLR (Homo sapiens) 6480464 2 more ... CTD PMID:31173147 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of LDLR mRNA CTD PMID:21215274 and PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of LDLR mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of LDLR mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Ldlr (Mus musculus) 6480464 [Tetrachlorodibenzodioxin affects the methylation of LDLR intron] which results in decreased expression of LDLR mRNA and [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of LDLR mRNA CTD PMID:25975270 and PMID:33017471 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Ldlr (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of LDLR mRNA CTD PMID:22539624 and PMID:22977169 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Ldlr (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of LDLR mRNA CTD PMID:21570461 more ... 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 2-bromohexadecanoic acid increases expression ISO LDLR (Homo sapiens) 6480464 2-bromopalmitate results in increased expression of LDLR mRNA CTD PMID:23150725 2-butoxyethanol increases expression ISO Ldlr (Mus musculus) 6480464 n-butoxyethanol results in increased expression of LDLR mRNA CTD PMID:19812364 2-methylcholine affects expression ISO LDLR (Homo sapiens) 6480464 beta-methylcholine affects the expression of LDLR mRNA CTD PMID:21179406 22-Hydroxycholesterol decreases expression ISO LDLR (Homo sapiens) 6480464 22-hydroxycholesterol results in decreased expression of LDLR mRNA CTD PMID:16142410 25-hydroxycholesterol multiple interactions ISO LDLR (Homo sapiens) 6480464 25-hydroxycholesterol inhibits the reaction [[Resveratrol results in increased activity of and results in increased cleavage of SREBF2 protein] which results in increased expression of LDLR mRNA] more ... CTD PMID:12477733 and PMID:22153697 25-hydroxycholesterol decreases expression ISO LDLR (Homo sapiens) 6480464 25-hydroxycholesterol results in decreased expression of LDLR protein CTD PMID:27447558 25-hydroxycholesterol decreases expression ISO Ldlr (Mus musculus) 6480464 25-hydroxycholesterol results in decreased expression of LDLR mRNA and 25-hydroxycholesterol results in decreased expression of LDLR protein CTD PMID:19260826 26-hydroxycholesterol decreases activity ISO LDLR (Homo sapiens) 6480464 27-hydroxycholesterol results in decreased activity of LDLR protein CTD PMID:8820113 26-hydroxycholesterol decreases expression EXP 6480464 27-hydroxycholesterol results in decreased expression of LDLR mRNA and 27-hydroxycholesterol results in decreased expression of LDLR protein CTD PMID:28167099 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:23196670 3,3',4,4',5-pentachlorobiphenyl increases expression ISO LDLR (Homo sapiens) 6480464 3 more ... CTD PMID:35618242 3,3',4,4',5-pentachlorobiphenyl increases response to substance ISO Ldlr (Mus musculus) 6480464 LDLR gene mutant form results in increased susceptibility to 3 more ... CTD PMID:29216392 3,3',5-triiodo-L-thyronine multiple interactions ISO LDLR (Homo sapiens) 6480464 Amiodarone promotes the reaction [Triiodothyronine results in increased expression of LDLR mRNA] and desethylamiodarone promotes the reaction [Triiodothyronine results in increased expression of LDLR mRNA] CTD PMID:9712728 3,3',5-triiodo-L-thyronine increases expression EXP 6480464 Triiodothyronine results in increased expression of LDLR mRNA CTD PMID:9071962 3,3',5-triiodo-L-thyronine multiple interactions EXP 6480464 Triiodothyronine inhibits the reaction [Amiodarone results in decreased expression of LDLR protein] CTD PMID:9071962 3,3',5-triiodo-L-thyronine increases expression ISO LDLR (Homo sapiens) 6480464 Triiodothyronine results in increased expression of LDLR mRNA CTD PMID:9712728 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin results in decreased expression of LDLR mRNA CTD PMID:28522335 3-methylcholanthrene decreases expression ISO Ldlr (Mus musculus) 6480464 Methylcholanthrene results in decreased expression of LDLR mRNA CTD PMID:35487396 4,4'-sulfonyldiphenol decreases expression ISO Ldlr (Mus musculus) 6480464 bisphenol S results in decreased expression of LDLR mRNA CTD PMID:33297965 4-hydroxy-TEMPO multiple interactions ISO LDLR (Homo sapiens) 6480464 tempol inhibits the reaction [LDLR gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]] CTD PMID:20530721 4-hydroxyphenyl retinamide decreases expression ISO Ldlr (Mus musculus) 6480464 Fenretinide results in decreased expression of LDLR mRNA CTD PMID:28973697 4-hydroxyphenyl retinamide decreases expression ISO LDLR (Homo sapiens) 6480464 Fenretinide results in decreased expression of LDLR mRNA CTD PMID:15958647 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of LDLR mRNA CTD PMID:24780913 and PMID:25825206 8-Br-cAMP increases expression ISO LDLR (Homo sapiens) 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of LDLR mRNA CTD PMID:22079614 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of LDLR mRNA CTD PMID:31881176 acetylsalicylic acid multiple interactions ISO LDLR (Homo sapiens) 6480464 Aspirin inhibits the reaction [LDLR gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]] more ... CTD PMID:10395027 and PMID:20530721 acetylsalicylic acid multiple interactions ISO Ldlr (Mus musculus) 6480464 Aspirin inhibits the reaction [LDLR gene mutant form results in decreased susceptibility to Arachidonic Acid] CTD PMID:20530721 acrolein multiple interactions ISO LDLR (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of LDLR mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of LDLR mRNA CTD PMID:32699268 acrylamide multiple interactions ISO Ldlr (Mus musculus) 6480464 Acrylamide inhibits the reaction [Streptozocin results in decreased expression of LDLR mRNA] CTD PMID:34896238 acrylamide increases expression ISO Ldlr (Mus musculus) 6480464 Acrylamide results in increased expression of LDLR mRNA CTD PMID:34896238 actinomycin D decreases expression ISO LDLR (Homo sapiens) 6480464 Dactinomycin results in decreased expression of LDLR mRNA CTD PMID:32913121 actinomycin D multiple interactions ISO LDLR (Homo sapiens) 6480464 Ascorbic Acid inhibits the reaction [Dactinomycin results in decreased expression of LDLR mRNA] CTD PMID:32913121 aflatoxin B1 affects expression ISO LDLR (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of LDLR protein CTD PMID:20106945 albuterol affects response to substance ISO LDLR (Homo sapiens) 6480464 LDLR gene SNP affects the susceptibility to Albuterol CTD PMID:15453913 aldehydo-D-glucose multiple interactions ISO Ldlr (Mus musculus) 6480464 [LDLR gene mutant form results in increased susceptibility to Pravastatin] inhibits the reaction [Glucose results in increased secretion of INS1 protein] CTD PMID:26875785 all-trans-retinoic acid increases expression ISO LDLR (Homo sapiens) 6480464 Tretinoin results in increased expression of LDLR mRNA CTD PMID:15894607 alpha-pinene multiple interactions ISO LDLR (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of LDLR mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of LDLR mRNA CTD PMID:32699268 amiodarone multiple interactions ISO LDLR (Homo sapiens) 6480464 Amiodarone promotes the reaction [Triiodothyronine results in increased expression of LDLR mRNA] CTD PMID:9712728 amiodarone decreases expression EXP 6480464 Amiodarone results in decreased expression of LDLR mRNA and Amiodarone results in decreased expression of LDLR protein CTD PMID:12538616 more ... amiodarone decreases expression ISO LDLR (Homo sapiens) 6480464 Amiodarone results in decreased expression of LDLR mRNA CTD PMID:9712728 amiodarone multiple interactions EXP 6480464 Triiodothyronine inhibits the reaction [Amiodarone results in decreased expression of LDLR protein] CTD PMID:9071962 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of LDLR mRNA CTD PMID:16483693 amphotericin B multiple interactions ISO Ldlr (Mus musculus) 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA] and [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA CTD PMID:36464106 ampicillin multiple interactions ISO Ldlr (Mus musculus) 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA] and [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA CTD PMID:36464106 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO LDLR (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [Quercetin results in increased expression of LDLR mRNA] and pyrazolanthrone inhibits the reaction [Quercetin results in increased expression of LDLR protein] CTD PMID:22388943 arachidonic acid multiple interactions ISO Ldlr (Mus musculus) 6480464 Aspirin inhibits the reaction [LDLR gene mutant form results in decreased susceptibility to Arachidonic Acid] more ... CTD PMID:20530721 arachidonic acid decreases response to substance ISO Ldlr (Mus musculus) 6480464 LDLR gene mutant form results in decreased susceptibility to Arachidonic Acid CTD PMID:20530721 arachidonic acid multiple interactions ISO LDLR (Homo sapiens) 6480464 Aspirin inhibits the reaction [LDLR gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]] more ... CTD PMID:20530721 Archazolid B increases expression ISO LDLR (Homo sapiens) 6480464 archazolid B results in increased expression of LDLR mRNA CTD PMID:25218289 argatroban multiple interactions ISO Ldlr (Mus musculus) 6480464 argatroban inhibits the reaction [[LDLR gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of Cholesterol] and argatroban inhibits the reaction [[LDLR gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of Triglycerides] CTD PMID:22841818 arsane affects methylation ISO LDLR (Homo sapiens) 6480464 Arsenic affects the methylation of LDLR gene CTD PMID:25304211 arsenic atom affects methylation ISO LDLR (Homo sapiens) 6480464 Arsenic affects the methylation of LDLR gene CTD PMID:25304211 atazanavir sulfate multiple interactions ISO LDLR (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of LDLR mRNA CTD PMID:33819548 atorvastatin calcium increases activity ISO LDLR (Homo sapiens) 6480464 Atorvastatin results in increased activity of LDLR protein CTD PMID:11728391 and PMID:12612140 atorvastatin calcium multiple interactions EXP 6480464 Atorvastatin inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in decreased expression of LDLR mRNA] and Atorvastatin inhibits the reaction [Dietary Fats results in decreased expression of LDLR mRNA] CTD PMID:30273964 and PMID:32048413 atorvastatin calcium increases expression EXP 6480464 Atorvastatin results in increased expression of LDLR mRNA CTD PMID:24502637 atorvastatin calcium increases expression ISO LDLR (Homo sapiens) 6480464 Atorvastatin results in increased expression of LDLR mRNA CTD PMID:10357840 and PMID:11728391 atrazine affects response to substance ISO LDLR (Homo sapiens) 6480464 LDLR gene SNP affects the susceptibility to Atrazine CTD PMID:22919386 atrazine increases expression ISO Ldlr (Mus musculus) 6480464 Atrazine results in increased expression of LDLR mRNA CTD PMID:33324343 atrazine decreases expression ISO Ldlr (Mus musculus) 6480464 Atrazine results in decreased expression of LDLR mRNA CTD PMID:26518232 aucubin multiple interactions ISO Ldlr (Mus musculus) 6480464 aucubin affects the reaction [[LDLR protein affects the susceptibility to Dietary Fats] which affects the expression of IL1B mRNA] more ... CTD PMID:36108984 avobenzone increases expression ISO LDLR (Homo sapiens) 6480464 avobenzone results in increased expression of LDLR mRNA CTD PMID:31016361 Azaspiracid increases expression ISO LDLR (Homo sapiens) 6480464 azaspiracid results in increased expression of LDLR mRNA CTD PMID:28939011 azoxystrobin affects expression ISO LDLR (Homo sapiens) 6480464 azoxystrobin affects the expression of LDLR mRNA CTD PMID:33512557 bathocuproine disulfonic acid multiple interactions ISO LDLR (Homo sapiens) 6480464 bathocuproine sulfonate inhibits the reaction [copper histidine results in increased expression of LDLR mRNA] CTD PMID:24170205 benzalkonium chloride increases expression ISO Ldlr (Mus musculus) 6480464 Benzalkonium Compounds results in increased expression of LDLR mRNA CTD PMID:31199489 benzo[a]pyrene decreases expression ISO LDLR (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of LDLR mRNA CTD PMID:20064835 and PMID:32234424 benzo[a]pyrene affects expression ISO Ldlr (Mus musculus) 6480464 Benzo(a)pyrene affects the expression of LDLR protein CTD PMID:30664314 benzo[a]pyrene diol epoxide I decreases expression ISO LDLR (Homo sapiens) 6480464 7 more ... CTD PMID:19150397 berberine multiple interactions ISO Ldlr (Mus musculus) 6480464 Berberine inhibits the reaction [Clozapine results in increased expression of LDLR mRNA] and Berberine inhibits the reaction [Risperidone results in increased expression of LDLR mRNA] CTD PMID:20564506 berberine increases expression EXP 6480464 Berberine results in increased expression of LDLR mRNA CTD PMID:18640378 berberine multiple interactions EXP 6480464 Berberine promotes the reaction [Simvastatin results in increased expression of LDLR mRNA] and Simvastatin promotes the reaction [Berberine results in increased expression of LDLR mRNA] CTD PMID:18640378 bicalutamide affects localization ISO LDLR (Homo sapiens) 6480464 bicalutamide affects the localization of LDLR protein CTD PMID:17440980 bifenthrin decreases expression ISO Ldlr (Mus musculus) 6480464 bifenthrin results in decreased expression of LDLR mRNA CTD PMID:24449165 and PMID:32408700 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of LDLR mRNA CTD PMID:15728792 more ... bis(2-ethylhexyl) phthalate decreases expression ISO Ldlr (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of LDLR mRNA CTD PMID:27405655 bis(2-ethylhexyl) phthalate multiple interactions ISO Ldlr (Mus musculus) 6480464 [APOE gene mutant form results in increased susceptibility to Diethylhexyl Phthalate] which results in decreased expression of LDLR protein and [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of LDLR mRNA CTD PMID:25270622 and PMID:35739755 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [Clofibrate co-treated with Diethylhexyl Phthalate] results in increased expression of LDLR mRNA CTD PMID:9207284 bisphenol A increases expression ISO Ldlr (Mus musculus) 6480464 bisphenol A results in increased expression of LDLR mRNA CTD PMID:23704952 and PMID:25270620 bisphenol A multiple interactions ISO Ldlr (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of LDLR mRNA and [LDLR protein affects the susceptibility to bisphenol A] which affects the expression of APOA1 mRNA CTD PMID:31842455 and PMID:35739755 bisphenol A affects response to substance ISO Ldlr (Mus musculus) 6480464 LDLR protein affects the susceptibility to bisphenol A CTD PMID:31842455 bisphenol A decreases expression ISO LDLR (Homo sapiens) 6480464 bisphenol A analog results in decreased expression of LDLR mRNA CTD PMID:32387340 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of LDLR mRNA CTD PMID:30816183 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of LDLR mRNA CTD PMID:30903817 bisphenol A affects expression ISO LDLR (Homo sapiens) 6480464 bisphenol A affects the expression of LDLR mRNA CTD PMID:30903817 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of LDLR mRNA and bisphenol A results in increased expression of LDLR protein CTD PMID:25181051 more ... bisphenol A increases expression ISO LDLR (Homo sapiens) 6480464 bisphenol A results in increased expression of LDLR mRNA CTD PMID:25047013 more ... bromobenzene decreases expression EXP 6480464 bromobenzene results in decreased expression of LDLR mRNA CTD PMID:32479839 butan-1-ol multiple interactions ISO LDLR (Homo sapiens) 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of LDLR mRNA CTD PMID:29432896 Butylbenzyl phthalate decreases expression EXP 6480464 butylbenzyl phthalate results in decreased expression of LDLR mRNA CTD PMID:15728792 Butylbenzyl phthalate multiple interactions ISO Ldlr (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of LDLR mRNA CTD PMID:35739755 cadmium atom decreases expression ISO LDLR (Homo sapiens) 6480464 Cadmium results in decreased expression of LDLR mRNA CTD PMID:12080015 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of LDLR mRNA CTD PMID:33453195 caffeine multiple interactions EXP 6480464 [Caffeine co-treated with Dietary Fats] results in decreased expression of LDLR mRNA and Caffeine promotes the reaction [Dietary Fats results in decreased expression of LDLR mRNA] CTD PMID:29800656 caffeine decreases phosphorylation ISO LDLR (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of LDLR protein CTD PMID:35688186 calciol multiple interactions EXP 6480464 [Cholecalciferol co-treated with Dietary Fats co-treated with Particulate Matter] results in increased expression of LDLR mRNA CTD PMID:36603807 calcitriol increases expression ISO LDLR (Homo sapiens) 6480464 Calcitriol results in increased expression of LDLR mRNA CTD PMID:26485663 captan increases expression ISO Ldlr (Mus musculus) 6480464 Captan results in increased expression of LDLR mRNA CTD PMID:31558096 carbamazepine decreases expression ISO LDLR (Homo sapiens) 6480464 Carbamazepine results in decreased expression of LDLR mRNA CTD PMID:21123845 carbamazepine affects expression ISO Ldlr (Mus musculus) 6480464 Carbamazepine affects the expression of LDLR mRNA CTD PMID:22634333 carbofuran affects response to substance ISO LDLR (Homo sapiens) 6480464 LDLR gene SNP affects the susceptibility to Carbofuran CTD PMID:22919386 carbon nanotube increases expression ISO LDLR (Homo sapiens) 6480464 Nanotubes and Carbon results in increased expression of LDLR mRNA CTD PMID:24389112 carbon nanotube increases expression ISO Ldlr (Mus musculus) 6480464 Nanotubes and Carbon results in increased expression of LDLR mRNA CTD PMID:25554681 carbon nanotube decreases expression ISO Ldlr (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25448806 and PMID:25620056 carmustine affects uptake ISO LDLR (Homo sapiens) 6480464 LDLR protein affects the uptake of Carmustine analog CTD PMID:12107554 celastrol increases expression ISO LDLR (Homo sapiens) 6480464 celastrol results in increased expression of LDLR mRNA CTD PMID:17010675 chenodeoxycholic acid multiple interactions ISO LDLR (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of LDLR mRNA more ... CTD PMID:33819548 chlordecone increases expression ISO Ldlr (Mus musculus) 6480464 Chlordecone results in increased expression of LDLR mRNA CTD PMID:29980752 chloroquine multiple interactions ISO Ldlr (Mus musculus) 6480464 Chloroquine affects the reaction [SORT1 protein affects the reaction [LDLR protein affects the abundance of Cholesterol]] CTD PMID:30950489 chlorpromazine increases expression ISO LDLR (Homo sapiens) 6480464 Chlorpromazine results in increased expression of LDLR mRNA CTD PMID:17052361 cholesterol increases uptake ISO LDLR (Homo sapiens) 6480464 LDLR protein results in increased uptake of Cholesterol CTD PMID:16477808 cholesterol affects abundance ISO Ldlr (Mus musculus) 6480464 LDLR protein affects the abundance of Cholesterol CTD PMID:30950489 cholesterol increases response to substance ISO Ldlr (Mus musculus) 6480464 LDLR gene mutant form results in increased susceptibility to Cholesterol CTD PMID:25263595 cholesterol multiple interactions ISO Ldlr (Mus musculus) 6480464 (+)-JQ1 compound inhibits the reaction [LDLR gene mutant form results in increased susceptibility to Cholesterol] more ... CTD PMID:22659316 more ... cholesterol decreases expression EXP 6480464 Cholesterol results in decreased expression of LDLR mRNA CTD PMID:16271152 more ... cholesterol multiple interactions EXP 6480464 [Cholesterol co-treated with Cholic Acid] results in decreased expression of LDLR mRNA more ... CTD PMID:16937255 more ... cholesterol multiple interactions ISO LDLR (Homo sapiens) 6480464 [CYP27A1 protein results in increased chemical synthesis of Bile Acids and Salts] promotes the reaction [LDLR protein results in increased uptake of Cholesterol] more ... CTD PMID:12477733 and PMID:16477808 cholesterol decreases activity EXP 6480464 Cholesterol results in decreased activity of LDLR protein CTD PMID:16271152 more ... cholic acid multiple interactions EXP 6480464 [Cholesterol co-treated with Cholic Acid] results in decreased expression of LDLR mRNA more ... CTD PMID:30273964 choline multiple interactions ISO Ldlr (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of LDLR mRNA CTD PMID:20938992 chromium(6+) affects expression ISO Ldlr (Mus musculus) 6480464 chromium hexavalent ion affects the expression of LDLR mRNA CTD PMID:28472532 chromium(6+) decreases expression ISO LDLR (Homo sapiens) 6480464 chromium hexavalent ion results in decreased expression of LDLR mRNA CTD PMID:30690063 ciguatoxin CTX1B affects expression ISO Ldlr (Mus musculus) 6480464 Ciguatoxins affects the expression of LDLR mRNA CTD PMID:18353800 cisplatin decreases expression ISO LDLR (Homo sapiens) 6480464 Cisplatin results in decreased expression of LDLR mRNA CTD PMID:27594783 cisplatin multiple interactions ISO LDLR (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of LDLR mRNA and Cisplatin inhibits the reaction [Piroxicam results in decreased expression of LDLR mRNA] CTD PMID:21858171 and PMID:27392435 cisplatin increases expression ISO Ldlr (Mus musculus) 6480464 Cisplatin results in increased expression of LDLR mRNA CTD PMID:21151649 clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of LDLR mRNA CTD PMID:17126302 clofibrate multiple interactions EXP 6480464 [Clofibrate co-treated with Diethylhexyl Phthalate] results in increased expression of LDLR mRNA CTD PMID:9207284 clozapine increases expression ISO Ldlr (Mus musculus) 6480464 Clozapine results in increased expression of LDLR mRNA CTD PMID:20564506 clozapine increases expression ISO LDLR (Homo sapiens) 6480464 Clozapine results in increased expression of LDLR mRNA CTD PMID:17052361 clozapine multiple interactions ISO Ldlr (Mus musculus) 6480464 Berberine inhibits the reaction [Clozapine results in increased expression of LDLR mRNA] CTD PMID:20564506 cobalt dichloride decreases expression ISO LDLR (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of LDLR mRNA CTD PMID:19320972 cobalt dichloride increases expression ISO LDLR (Homo sapiens) 6480464 cobaltous chloride results in increased expression of LDLR mRNA CTD PMID:19376846 colesevelam hydrochloride increases expression ISO Ldlr (Mus musculus) 6480464 Colesevelam Hydrochloride results in increased expression of LDLR mRNA CTD PMID:22120639 copper atom decreases expression ISO LDLR (Homo sapiens) 6480464 Copper results in decreased expression of LDLR mRNA CTD PMID:17205981 copper atom decreases expression EXP 6480464 Copper results in decreased expression of LDLR mRNA CTD PMID:30556269 copper atom decreases expression ISO Ldlr (Mus musculus) 6480464 Copper results in decreased expression of LDLR mRNA CTD PMID:17205981 copper(0) decreases expression ISO LDLR (Homo sapiens) 6480464 Copper results in decreased expression of LDLR mRNA CTD PMID:17205981 copper(0) decreases expression EXP 6480464 Copper results in decreased expression of LDLR mRNA CTD PMID:30556269 copper(0) decreases expression ISO Ldlr (Mus musculus) 6480464 Copper results in decreased expression of LDLR mRNA CTD PMID:17205981 copper(II) sulfate increases expression ISO LDLR (Homo sapiens) 6480464 Copper Sulfate results in increased expression of LDLR mRNA CTD PMID:12860252 and PMID:19549813 cortisol decreases expression ISO LDLR (Homo sapiens) 6480464 Hydrocortisone results in decreased expression of LDLR mRNA CTD PMID:31075344 cortisol multiple interactions ISO LDLR (Homo sapiens) 6480464 Mifepristone inhibits the reaction [Hydrocortisone results in decreased expression of LDLR mRNA] CTD PMID:31075344 coumestrol multiple interactions ISO LDLR (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of LDLR mRNA CTD PMID:19167446 crocidolite asbestos increases expression ISO LDLR (Homo sapiens) 6480464 Asbestos and Crocidolite results in increased expression of LDLR mRNA CTD PMID:25351596 crocin-1 multiple interactions EXP 6480464 crocin inhibits the reaction [Diazinon results in decreased expression of LDLR mRNA] CTD PMID:24132704 curcumin multiple interactions ISO LDLR (Homo sapiens) 6480464 Curcumin inhibits the reaction [INSIG2 protein results in decreased expression of LDLR mRNA] and Curcumin results in increased expression of and results in increased activity of LDLR protein CTD PMID:18704882 curcumin affects expression ISO Ldlr (Mus musculus) 6480464 Curcumin affects the expression of LDLR mRNA CTD PMID:27208389 curcumin increases expression ISO LDLR (Homo sapiens) 6480464 Curcumin results in increased expression of LDLR mRNA and Curcumin results in increased expression of LDLR protein CTD PMID:16713233 more ... cycloheximide decreases expression ISO LDLR (Homo sapiens) 6480464 Cycloheximide results in decreased expression of LDLR protein CTD PMID:22388943 cycloheximide multiple interactions ISO LDLR (Homo sapiens) 6480464 Cycloheximide inhibits the reaction [Quercetin results in increased expression of LDLR protein] CTD PMID:22388943 cyclosporin A multiple interactions ISO LDLR (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Cyclosporine] results in increased expression of LDLR mRNA more ... CTD PMID:10395027 and PMID:33819548 cyclosporin A increases expression ISO LDLR (Homo sapiens) 6480464 Cyclosporine results in increased expression of LDLR mRNA CTD PMID:20106945 more ... cyproconazole affects expression ISO Ldlr (Mus musculus) 6480464 cyproconazole affects the expression of LDLR mRNA CTD PMID:22045034 D-glucose multiple interactions ISO Ldlr (Mus musculus) 6480464 [LDLR gene mutant form results in increased susceptibility to Pravastatin] inhibits the reaction [Glucose results in increased secretion of INS1 protein] CTD PMID:26875785 DDE decreases expression EXP 6480464 Dichlorodiphenyl Dichloroethylene results in decreased expression of LDLR mRNA CTD PMID:15885261 deoxycholic acid multiple interactions ISO LDLR (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of LDLR mRNA more ... CTD PMID:33819548 desmosterol decreases expression ISO Ldlr (Mus musculus) 6480464 Desmosterol results in decreased expression of LDLR protein CTD PMID:19260826 desogestrel multiple interactions ISO LDLR (Homo sapiens) 6480464 [Desogestrel co-treated with Ethinyl Estradiol] results in increased expression of LDLR protein CTD PMID:17900441 desogestrel increases expression ISO LDLR (Homo sapiens) 6480464 Desogestrel results in increased expression of LDLR protein CTD PMID:17900441 dexamethasone increases expression ISO LDLR (Homo sapiens) 6480464 Dexamethasone results in increased expression of LDLR mRNA CTD PMID:25047013 dexamethasone decreases expression ISO LDLR (Homo sapiens) 6480464 Dexamethasone results in decreased expression of LDLR mRNA and Dexamethasone results in decreased expression of LDLR protein CTD PMID:32234517 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of LDLR mRNA and Dexamethasone results in decreased expression of LDLR protein CTD PMID:32234517 dexamethasone multiple interactions ISO LDLR (Homo sapiens) 6480464 Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of LDLR mRNA] more ... CTD PMID:32234517 Di-n-hexyl phthalate decreases expression EXP 6480464 di-n-hexyl phthalate results in decreased expression of LDLR mRNA CTD PMID:33983380 Di-n-octyl phthalate multiple interactions ISO Ldlr (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of LDLR mRNA CTD PMID:35739755 diazinon decreases expression EXP 6480464 Diazinon results in decreased expression of LDLR mRNA CTD PMID:24132704 diazinon multiple interactions EXP 6480464 crocin inhibits the reaction [Diazinon results in decreased expression of LDLR mRNA] CTD PMID:24132704 dibenzo[a,l]pyrene decreases expression ISO LDLR (Homo sapiens) 6480464 dibenzo(a and l)pyrene results in decreased expression of LDLR mRNA CTD PMID:16269432 dibutyl phthalate increases expression ISO Ldlr (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of LDLR mRNA CTD PMID:21266533 dibutyl phthalate multiple interactions ISO Ldlr (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of LDLR mRNA CTD PMID:35739755 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of LDLR mRNA CTD PMID:15728792 more ... dicrotophos increases expression ISO LDLR (Homo sapiens) 6480464 dicrotophos results in increased expression of LDLR mRNA CTD PMID:28302478 Dicyclohexyl phthalate decreases expression EXP 6480464 dicyclohexyl phthalate results in decreased expression of LDLR mRNA CTD PMID:33983380 dieldrin increases expression ISO LDLR (Homo sapiens) 6480464 Dieldrin results in increased expression of LDLR mRNA CTD PMID:31068361 diethyl maleate decreases expression EXP 6480464 diethyl maleate results in decreased expression of LDLR mRNA CTD PMID:21161181 diethyl phthalate multiple interactions ISO Ldlr (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of LDLR mRNA CTD PMID:35739755 diisobutyl phthalate decreases expression EXP 6480464 diisobutyl phthalate results in decreased expression of LDLR mRNA CTD PMID:33983380 Diisodecyl phthalate multiple interactions ISO Ldlr (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of LDLR mRNA CTD PMID:35739755 diisononyl phthalate decreases expression EXP 6480464 diisononyl phthalate results in decreased expression of LDLR mRNA CTD PMID:33983380 diisononyl phthalate multiple interactions ISO Ldlr (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of LDLR mRNA CTD PMID:35739755 dimethylarsinic acid multiple interactions ISO Ldlr (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of LDLR mRNA CTD PMID:34876320 dinophysistoxin 1 increases expression ISO LDLR (Homo sapiens) 6480464 dinophysistoxin 1 results in increased expression of LDLR mRNA CTD PMID:28939011 dioxygen multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of LDLR mRNA CTD PMID:33729688 dipentyl phthalate decreases expression EXP 6480464 di-n-pentyl phthalate results in decreased expression of LDLR mRNA CTD PMID:15728792 and PMID:33983380 disodium selenite multiple interactions ISO Ldlr (Mus musculus) 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA] CTD PMID:36464106 diuron decreases expression ISO LDLR (Homo sapiens) 6480464 Diuron results in decreased expression of LDLR mRNA CTD PMID:35967413 dorsomorphin multiple interactions ISO LDLR (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LDLR mRNA CTD PMID:27188386 doxorubicin decreases expression ISO LDLR (Homo sapiens) 6480464 Doxorubicin results in decreased expression of LDLR mRNA CTD PMID:29803840 elemental selenium multiple interactions EXP 6480464 Selenium inhibits the reaction [Cholesterol results in decreased activity of LDLR protein] and Selenium inhibits the reaction [Cholesterol results in decreased expression of LDLR mRNA] CTD PMID:16937255 elemental selenium multiple interactions ISO Ldlr (Mus musculus) 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA] CTD PMID:36464106 elemental selenium increases expression EXP 6480464 Selenium results in increased expression of LDLR mRNA CTD PMID:16271152 elemental selenium increases activity EXP 6480464 Selenium results in increased activity of LDLR protein CTD PMID:16271152 elemental selenium decreases activity EXP 6480464 Selenium deficiency results in decreased activity of LDLR protein CTD PMID:16317514 elemental selenium decreases expression EXP 6480464 Selenium deficiency results in decreased expression of LDLR mRNA CTD PMID:16317514 endosulfan affects expression EXP 6480464 Endosulfan affects the expression of LDLR mRNA CTD PMID:29391264 Enterolactone multiple interactions ISO LDLR (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of LDLR mRNA CTD PMID:19167446 epoxiconazole increases expression EXP 6480464 epoxiconazole results in increased expression of LDLR mRNA CTD PMID:28454766 epoxiconazole decreases expression ISO Ldlr (Mus musculus) 6480464 epoxiconazole results in decreased expression of LDLR mRNA CTD PMID:35436446 ethanol increases expression EXP 6480464 Ethanol results in increased expression of LDLR mRNA CTD PMID:15353170 ethanol affects expression ISO Ldlr (Mus musculus) 6480464 Ethanol affects the expression of LDLR mRNA CTD PMID:30319688 ethanol increases expression ISO Ldlr (Mus musculus) 6480464 Ethanol results in increased expression of LDLR mRNA CTD PMID:30319688 ethanol multiple interactions ISO LDLR (Homo sapiens) 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of LDLR mRNA more ... CTD PMID:29432896 and PMID:31226463 ethanol decreases expression ISO LDLR (Homo sapiens) 6480464 Ethanol results in decreased expression of LDLR mRNA and Ethanol results in decreased expression of LDLR protein CTD PMID:31226463 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of LDLR mRNA and Ethanol results in decreased expression of LDLR protein CTD PMID:31075344 and PMID:31226463 ethyl methanesulfonate decreases expression ISO LDLR (Homo sapiens) 6480464 Ethyl Methanesulfonate results in decreased expression of LDLR mRNA CTD PMID:23649840 ezetimibe multiple interactions ISO LDLR (Homo sapiens) 6480464 [Simvastatin co-treated with Ezetimibe] results in increased expression of LDLR mRNA CTD PMID:17980884 fenthion increases expression ISO Ldlr (Mus musculus) 6480464 Fenthion results in increased expression of LDLR mRNA CTD PMID:34813904 flufenamic acid multiple interactions ISO LDLR (Homo sapiens) 6480464 Flufenamic Acid inhibits the reaction [Cyclosporine inhibits the reaction [[Cholesterol more ... CTD PMID:10395027 flufenamic acid increases expression ISO LDLR (Homo sapiens) 6480464 Flufenamic Acid results in increased expression of LDLR mRNA and Flufenamic Acid results in increased expression of LDLR protein CTD PMID:10395027 fluoranthene decreases expression ISO Ldlr (Mus musculus) 6480464 fluoranthene results in decreased expression of LDLR mRNA CTD PMID:28329830 fluoranthene multiple interactions ISO Ldlr (Mus musculus) 6480464 [1-methylanthracene co-treated with fluoranthene] results in decreased expression of LDLR mRNA CTD PMID:28329830 flusilazole affects expression ISO Ldlr (Mus musculus) 6480464 flusilazole affects the expression of LDLR mRNA CTD PMID:21195148 and PMID:22634333 flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of LDLR mRNA CTD PMID:15885261 fluvastatin multiple interactions ISO LDLR (Homo sapiens) 6480464 [APOB gene SNP co-treated with APOE gene SNP co-treated with HMGCR gene SNP co-treated with LDLR gene SNP co-treated with PCSK9 gene SNP co-treated with ABCA1 gene SNP co-treated with CETP gene SNP co-treated with LIPC gene SNP co-treated with LPL gene SNP] affects the susceptibility to fluvastatin more ... CTD PMID:10395027 and PMID:19773416 fluvastatin increases activity ISO LDLR (Homo sapiens) 6480464 fluvastatin results in increased activity of LDLR protein CTD PMID:8593127 folic acid multiple interactions ISO Ldlr (Mus musculus) 6480464 [1 more ... CTD PMID:20938992 and PMID:22206623 folic acid decreases expression ISO LDLR (Homo sapiens) 6480464 Folic Acid results in decreased expression of LDLR mRNA CTD PMID:21867686 formaldehyde decreases expression ISO LDLR (Homo sapiens) 6480464 Formaldehyde results in decreased expression of LDLR mRNA CTD PMID:23649840 gallic acid increases expression ISO LDLR (Homo sapiens) 6480464 Gallic Acid results in increased expression of LDLR mRNA CTD PMID:12612140 Ganoderic acid A decreases expression ISO LDLR (Homo sapiens) 6480464 ganoderic acid A results in decreased expression of LDLR mRNA CTD PMID:29852127 Ganoderic acid A multiple interactions ISO Ldlr (Mus musculus) 6480464 [Dietary Fats co-treated with ganoderic acid A] affects the expression of LDLR mRNA CTD PMID:29852127 gedunin increases expression ISO LDLR (Homo sapiens) 6480464 gedunin results in increased expression of LDLR mRNA CTD PMID:17010675 genistein increases expression ISO Ldlr (Mus musculus) 6480464 Genistein results in increased expression of LDLR mRNA CTD PMID:32186404 geraniol increases expression ISO Ldlr (Mus musculus) 6480464 geraniol results in increased expression of LDLR mRNA CTD PMID:26141755 Ginsenoside Rh4 multiple interactions ISO Ldlr (Mus musculus) 6480464 ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of LDLR mRNA] CTD PMID:33359794 glucose multiple interactions ISO Ldlr (Mus musculus) 6480464 [LDLR gene mutant form results in increased susceptibility to Pravastatin] inhibits the reaction [Glucose results in increased secretion of INS1 protein] CTD PMID:26875785 glycochenodeoxycholic acid multiple interactions ISO LDLR (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of LDLR mRNA more ... CTD PMID:33819548 glycocholic acid multiple interactions ISO LDLR (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of LDLR mRNA more ... CTD PMID:33819548 glycodeoxycholic acid multiple interactions ISO LDLR (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of LDLR mRNA more ... CTD PMID:33819548 graphene oxide increases expression ISO Ldlr (Mus musculus) 6480464 graphene oxide results in increased expression of LDLR mRNA CTD PMID:33227293 GW 3965 decreases expression ISO LDLR (Homo sapiens) 6480464 GW 3965 results in decreased expression of LDLR protein CTD PMID:27598782 haloperidol increases expression ISO LDLR (Homo sapiens) 6480464 Haloperidol results in increased expression of LDLR mRNA CTD PMID:17052361 hexaconazole affects expression ISO Ldlr (Mus musculus) 6480464 hexaconazole affects the expression of LDLR mRNA CTD PMID:21195148 hexadecanoic acid multiple interactions ISO LDLR (Homo sapiens) 6480464 [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of LDLR mRNA CTD PMID:30547786 hydrazine increases expression ISO Ldlr (Mus musculus) 6480464 hydrazine results in increased expression of LDLR mRNA CTD PMID:15282401 hydrogen peroxide increases expression ISO LDLR (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of LDLR mRNA CTD PMID:12414654 hydrogen peroxide increases expression ISO Ldlr (Mus musculus) 6480464 Hydrogen Peroxide results in increased expression of LDLR protein CTD PMID:29499335 hydrogen peroxide multiple interactions ISO Ldlr (Mus musculus) 6480464 Metformin inhibits the reaction [Hydrogen Peroxide results in increased expression of LDLR protein] CTD PMID:29499335 hydrogen peroxide multiple interactions ISO LDLR (Homo sapiens) 6480464 [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of LDLR mRNA CTD PMID:18032389 ibuprofen multiple interactions ISO LDLR (Homo sapiens) 6480464 Ibuprofen promotes the reaction [[Cholesterol more ... CTD PMID:10395027 indometacin multiple interactions ISO Ldlr (Mus musculus) 6480464 Indomethacin promotes the reaction [LDLR gene mutant form results in decreased susceptibility to Arachidonic Acid] CTD PMID:20530721 indometacin increases expression ISO LDLR (Homo sapiens) 6480464 Indomethacin results in increased expression of LDLR mRNA and Indomethacin results in increased expression of LDLR protein CTD PMID:10395027 indometacin multiple interactions ISO LDLR (Homo sapiens) 6480464 fluvastatin promotes the reaction [Indomethacin promotes the reaction [Cholesterol more ... CTD PMID:10395027 isobutanol multiple interactions ISO LDLR (Homo sapiens) 6480464 [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of LDLR mRNA CTD PMID:29432896 isoflavones affects expression ISO LDLR (Homo sapiens) 6480464 Isoflavones affects the expression of LDLR mRNA CTD PMID:16365062 isotretinoin decreases expression ISO LDLR (Homo sapiens) 6480464 Isotretinoin results in decreased expression of LDLR mRNA CTD PMID:20436886 L-ascorbic acid increases expression ISO Ldlr (Mus musculus) 6480464 Ascorbic Acid results in increased expression of LDLR mRNA and Ascorbic Acid results in increased expression of LDLR protein CTD PMID:32913121 L-ascorbic acid multiple interactions ISO Ldlr (Mus musculus) 6480464 Ascorbic Acid affects the reaction [GULO protein affects the expression of LDLR protein] CTD PMID:32913121 L-ascorbic acid increases expression ISO LDLR (Homo sapiens) 6480464 Ascorbic Acid results in increased expression of LDLR mRNA and Ascorbic Acid results in increased expression of LDLR protein CTD PMID:32913121 L-ascorbic acid multiple interactions ISO LDLR (Homo sapiens) 6480464 Ascorbic Acid inhibits the reaction [Dactinomycin results in decreased expression of LDLR mRNA] more ... CTD PMID:32913121 L-methionine multiple interactions ISO Ldlr (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of LDLR mRNA CTD PMID:20938992 lead diacetate decreases expression ISO Ldlr (Mus musculus) 6480464 lead acetate results in decreased expression of LDLR mRNA CTD PMID:25270620 lead diacetate decreases expression EXP 6480464 lead acetate results in decreased expression of LDLR mRNA and lead acetate results in decreased expression of LDLR protein CTD PMID:29908845 lead(0) affects expression EXP 6480464 Lead affects the expression of LDLR CTD PMID:22001170 lead(0) increases localization EXP 6480464 Lead results in increased localization of LDLR protein CTD PMID:20488202 lead(0) multiple interactions EXP 6480464 PRKCD protein promotes the reaction [Lead results in increased localization of LDLR protein] more ... CTD PMID:20488202 and PMID:22001170 leflunomide increases expression ISO LDLR (Homo sapiens) 6480464 leflunomide results in increased expression of LDLR mRNA CTD PMID:28988120 leflunomide decreases expression ISO Ldlr (Mus musculus) 6480464 leflunomide results in decreased expression of LDLR mRNA CTD PMID:19751817 levonorgestrel affects expression ISO LDLR (Homo sapiens) 6480464 Levonorgestrel affects the expression of LDLR protein CTD PMID:17900441 levonorgestrel multiple interactions ISO LDLR (Homo sapiens) 6480464 [Levonorgestrel co-treated with Ethinyl Estradiol] results in decreased expression of LDLR protein CTD PMID:17900441 lipopolysaccharide multiple interactions ISO LDLR (Homo sapiens) 6480464 [NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of LDLR mRNA more ... CTD PMID:33677747 and PMID:35877022 lipopolysaccharide increases expression ISO Ldlr (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of LDLR mRNA CTD PMID:12057914 lipopolysaccharide decreases expression ISO Ldlr (Mus musculus) 6480464 Lipopolysaccharides results in decreased expression of LDLR mRNA and Lipopolysaccharides results in decreased expression of LDLR protein CTD PMID:18638454 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of LDLR protein CTD PMID:33677747 lipopolysaccharide multiple interactions EXP 6480464 ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Lipopolysaccharides results in increased expression of LDLR protein] and SREBF2 protein affects the reaction [Lipopolysaccharides results in increased expression of LDLR protein] CTD PMID:33677747 lipopolysaccharide increases expression ISO LDLR (Homo sapiens) 6480464 Lipopolysaccharides results in increased expression of LDLR mRNA and Lipopolysaccharides results in increased expression of LDLR protein CTD PMID:33677747 lithocholic acid decreases expression ISO Ldlr (Mus musculus) 6480464 Lithocholic Acid results in decreased expression of LDLR mRNA CTD PMID:20359477 lovastatin multiple interactions ISO LDLR (Homo sapiens) 6480464 OSM protein promotes the reaction [Lovastatin results in increased expression of LDLR mRNA] CTD PMID:12524230 lovastatin multiple interactions ISO Ldlr (Mus musculus) 6480464 [Dietary Fats co-treated with Lovastatin] affects the expression of LDLR mRNA CTD PMID:29852127 lovastatin multiple interactions EXP 6480464 [Cholesterol deficiency co-treated with Lovastatin] results in increased expression of LDLR mRNA and Cholesterol inhibits the reaction [[Cholesterol deficiency co-treated with Lovastatin] results in increased expression of LDLR mRNA] CTD PMID:20578043 lovastatin increases activity ISO LDLR (Homo sapiens) 6480464 Lovastatin results in increased activity of LDLR protein CTD PMID:11728391 and PMID:8593127 lovastatin increases expression ISO LDLR (Homo sapiens) 6480464 Lovastatin results in increased expression of LDLR mRNA CTD PMID:11728391 and PMID:12524230 lycopene increases expression ISO LDLR (Homo sapiens) 6480464 lycopene results in increased expression of LDLR mRNA CTD PMID:16886892 Maduramicin multiple interactions EXP 6480464 maduramicin affects the reaction [EGF protein affects the expression of LDLR protein] CTD PMID:37394175 menadione increases expression ISO LDLR (Homo sapiens) 6480464 Vitamin K 3 results in increased expression of LDLR mRNA CTD PMID:12414654 metformin multiple interactions ISO Ldlr (Mus musculus) 6480464 Metformin inhibits the reaction [AGT protein results in increased expression of LDLR protein] and Metformin inhibits the reaction [Hydrogen Peroxide results in increased expression of LDLR protein] CTD PMID:29499335 metformin multiple interactions ISO LDLR (Homo sapiens) 6480464 Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of LDLR protein] CTD PMID:29499335 methyl methanesulfonate decreases expression ISO LDLR (Homo sapiens) 6480464 Methyl Methanesulfonate results in decreased expression of LDLR mRNA CTD PMID:23649840 methylarsonic acid multiple interactions ISO Ldlr (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of LDLR mRNA CTD PMID:34876320 methylmercury chloride increases expression ISO LDLR (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of LDLR mRNA CTD PMID:28001369 metronidazole multiple interactions ISO Ldlr (Mus musculus) 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA] and [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA CTD PMID:36464106 microcystin-LR increases expression ISO Ldlr (Mus musculus) 6480464 cyanoginosin LR results in increased expression of LDLR mRNA CTD PMID:25497113 mifepristone multiple interactions ISO LDLR (Homo sapiens) 6480464 Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of LDLR mRNA] more ... CTD PMID:31075344 and PMID:32234517 mitogen increases expression ISO Ldlr (Mus musculus) 6480464 Mitogens results in increased expression of LDLR protein CTD PMID:30664314 monocrotophos increases expression EXP 6480464 Monocrotophos results in increased expression of LDLR mRNA CTD PMID:32267039 monosodium L-glutamate multiple interactions ISO Ldlr (Mus musculus) 6480464 [Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of LDLR mRNA CTD PMID:19001666 N-desethylamiodarone decreases expression ISO LDLR (Homo sapiens) 6480464 desethylamiodarone results in decreased expression of LDLR mRNA CTD PMID:9712728 N-desethylamiodarone multiple interactions ISO LDLR (Homo sapiens) 6480464 desethylamiodarone promotes the reaction [Triiodothyronine results in increased expression of LDLR mRNA] CTD PMID:9712728 nefazodone multiple interactions ISO LDLR (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of LDLR mRNA CTD PMID:33819548 neomycin multiple interactions ISO Ldlr (Mus musculus) 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA] and [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA CTD PMID:36464106 nickel atom increases expression ISO LDLR (Homo sapiens) 6480464 Nickel results in increased expression of LDLR mRNA CTD PMID:23195993 and PMID:24768652 nickel dichloride decreases expression ISO LDLR (Homo sapiens) 6480464 nickel chloride results in decreased expression of LDLR mRNA CTD PMID:17312168 nicotine increases expression ISO LDLR (Homo sapiens) 6480464 Nicotine results in increased expression of LDLR mRNA CTD PMID:23416264 obeticholic acid decreases expression ISO LDLR (Homo sapiens) 6480464 obeticholic acid results in decreased expression of LDLR mRNA CTD PMID:27939613 okadaic acid increases expression ISO LDLR (Homo sapiens) 6480464 Okadaic Acid results in increased expression of LDLR mRNA CTD PMID:28939011 olanzapine increases expression ISO LDLR (Homo sapiens) 6480464 olanzapine results in increased expression of LDLR mRNA CTD PMID:17052361 olanzapine multiple interactions ISO Ldlr (Mus musculus) 6480464 olanzapine promotes the reaction [SREBF1 protein results in increased expression of LDLR mRNA] CTD PMID:17651982 oleic acid multiple interactions ISO LDLR (Homo sapiens) 6480464 [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of LDLR mRNA CTD PMID:30547786 ozone increases expression EXP 6480464 Ozone results in increased expression of LDLR mRNA CTD PMID:16330353 and PMID:29329427 ozone multiple interactions ISO LDLR (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of LDLR mRNA more ... CTD PMID:32699268 ozone multiple interactions EXP 6480464 Fish Oils inhibits the reaction [Ozone results in increased expression of LDLR mRNA] CTD PMID:29329427 paclitaxel affects response to substance ISO LDLR (Homo sapiens) 6480464 LDLR protein affects the susceptibility to Paclitaxel CTD PMID:16217747 paracetamol multiple interactions ISO LDLR (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of LDLR mRNA more ... CTD PMID:10395027 and PMID:33819548 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of LDLR mRNA CTD PMID:32479839 and PMID:33387578 paracetamol increases expression ISO LDLR (Homo sapiens) 6480464 Acetaminophen results in increased expression of LDLR mRNA CTD PMID:21420995 paraquat increases expression EXP 6480464 Paraquat results in increased expression of LDLR mRNA CTD PMID:32680482 paraquat decreases expression ISO LDLR (Homo sapiens) 6480464 Paraquat results in decreased expression of LDLR mRNA CTD PMID:34681664 perfluorononanoic acid decreases expression ISO LDLR (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in decreased expression of LDLR mRNA CTD PMID:32588087 perfluorooctane-1-sulfonic acid decreases expression ISO LDLR (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in decreased expression of LDLR mRNA CTD PMID:32253466 and PMID:32588087 perfluorooctane-1-sulfonic acid multiple interactions ISO Ldlr (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of LDLR mRNA CTD PMID:36331819 perfluorooctanoic acid increases expression ISO Ldlr (Mus musculus) 6480464 perfluorooctanoic acid results in increased expression of LDLR mRNA CTD PMID:17681415 and PMID:25092180 perfluorooctanoic acid decreases expression ISO LDLR (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of LDLR mRNA CTD PMID:32253466 perfluorooctanoic acid increases expression ISO LDLR (Homo sapiens) 6480464 perfluorooctanoic acid results in increased expression of LDLR protein CTD PMID:26879310 perfluorooctanoic acid decreases expression ISO Ldlr (Mus musculus) 6480464 perfluorooctanoic acid results in decreased expression of LDLR mRNA CTD PMID:26942110 and PMID:32822737 permethrin decreases expression EXP 6480464 Permethrin results in decreased expression of LDLR protein CTD PMID:32911180 Phenelzine decreases expression ISO Ldlr (Mus musculus) 6480464 Phenelzine results in decreased expression of LDLR mRNA CTD PMID:31249575 phenobarbital affects expression ISO LDLR (Homo sapiens) 6480464 Phenobarbital affects the expression of LDLR mRNA CTD PMID:19159669 phenobarbital affects expression ISO Ldlr (Mus musculus) 6480464 Phenobarbital affects the expression of LDLR mRNA CTD PMID:23091169 phenylephrine increases expression EXP 6480464 Phenylephrine results in increased expression of LDLR mRNA CTD PMID:18158353 phenylmercury acetate decreases expression ISO LDLR (Homo sapiens) 6480464 Phenylmercuric Acetate results in decreased expression of LDLR mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO LDLR (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LDLR mRNA CTD PMID:27188386 phenylpropanolamine increases expression ISO LDLR (Homo sapiens) 6480464 Phenylpropanolamine results in increased expression of LDLR mRNA CTD PMID:27756839 phorbol 13-acetate 12-myristate increases expression ISO LDLR (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate results in increased expression of LDLR mRNA and Tetradecanoylphorbol Acetate results in increased expression of LDLR protein CTD PMID:29499335 and PMID:31068361 phorbol 13-acetate 12-myristate multiple interactions ISO LDLR (Homo sapiens) 6480464 Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of LDLR protein] CTD PMID:29499335 phosgene affects expression ISO Ldlr (Mus musculus) 6480464 Phosgene affects the expression of LDLR mRNA CTD PMID:16300373 pioglitazone increases expression ISO Ldlr (Mus musculus) 6480464 pioglitazone results in increased expression of LDLR protein CTD PMID:22593575 pioglitazone multiple interactions ISO Ldlr (Mus musculus) 6480464 [pioglitazone co-treated with U 0126] affects the localization of LDLR protein CTD PMID:22593575 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of LDLR mRNA CTD PMID:17126302 pirinixic acid decreases expression ISO Ldlr (Mus musculus) 6480464 pirinixic acid results in decreased expression of LDLR mRNA CTD PMID:23811191 pirinixic acid decreases expression ISO LDLR (Homo sapiens) 6480464 pirinixic acid results in decreased expression of LDLR mRNA CTD PMID:23150725 pirinixic acid increases expression ISO Ldlr (Mus musculus) 6480464 pirinixic acid results in increased expression of LDLR mRNA CTD PMID:25270620 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of LDLR mRNA CTD PMID:19162173 pirinixic acid affects expression ISO Ldlr (Mus musculus) 6480464 pirinixic acid affects the expression of LDLR mRNA CTD PMID:18445702 piroxicam multiple interactions ISO LDLR (Homo sapiens) 6480464 Cisplatin inhibits the reaction [Piroxicam results in decreased expression of LDLR mRNA] CTD PMID:21858171 piroxicam decreases expression ISO LDLR (Homo sapiens) 6480464 Piroxicam results in decreased expression of LDLR mRNA CTD PMID:21858171 potassium chromate multiple interactions ISO LDLR (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of LDLR mRNA CTD PMID:22079256 potassium chromate decreases expression ISO LDLR (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of LDLR mRNA CTD PMID:22079256 and PMID:22714537 potassium dichromate increases expression ISO LDLR (Homo sapiens) 6480464 Potassium Dichromate results in increased expression of LDLR protein CTD PMID:23718831 pravastatin increases activity ISO LDLR (Homo sapiens) 6480464 Pravastatin results in increased activity of LDLR protein CTD PMID:8593127 pravastatin increases response to substance ISO Ldlr (Mus musculus) 6480464 [LDLR gene mutant form results in increased susceptibility to Pravastatin] which results in increased susceptibility to INS1 protein and LDLR gene mutant form results in increased susceptibility to Pravastatin CTD PMID:26875785 pravastatin multiple interactions ISO Ldlr (Mus musculus) 6480464 [LDLR gene mutant form results in increased susceptibility to Pravastatin] inhibits the reaction [Glucose results in increased secretion of INS1 protein] more ... CTD PMID:26875785 proanthocyanidin multiple interactions EXP 6480464 Proanthocyanidins inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in decreased expression of LDLR mRNA] CTD PMID:30273964 progesterone affects expression ISO Ldlr (Mus musculus) 6480464 Progesterone affects the expression of LDLR mRNA CTD PMID:17251523 progesterone increases expression ISO LDLR (Homo sapiens) 6480464 Progesterone results in increased expression of LDLR mRNA CTD PMID:18037150 and PMID:18070364 progesterone increases expression EXP 6480464 Progesterone results in increased expression of LDLR mRNA CTD PMID:17170212 propamocarb multiple interactions ISO Ldlr (Mus musculus) 6480464 propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of LDLR mRNA] CTD PMID:34426332 pterostilbene decreases expression ISO LDLR (Homo sapiens) 6480464 pterostilbene results in decreased expression of LDLR mRNA CTD PMID:22153697 puerarin multiple interactions EXP 6480464 puerarin affects the reaction [Lead affects the expression of LDLR] CTD PMID:22001170 puromycin multiple interactions ISO LDLR (Homo sapiens) 6480464 Puromycin inhibits the reaction [GW 707 results in increased expression of LDLR mRNA] more ... CTD PMID:12524230 and PMID:22388943 puromycin decreases expression ISO LDLR (Homo sapiens) 6480464 Puromycin results in decreased expression of LDLR mRNA and Puromycin results in decreased expression of LDLR protein CTD PMID:22388943 quercetin multiple interactions ISO LDLR (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in increased expression of LDLR mRNA] more ... CTD PMID:22388943 quercetin increases expression ISO LDLR (Homo sapiens) 6480464 Quercetin results in increased expression of LDLR mRNA and Quercetin results in increased expression of LDLR protein CTD PMID:21632981 and PMID:22388943 quercetin 3-O-beta-D-glucofuranoside multiple interactions ISO LDLR (Homo sapiens) 6480464 [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of LDLR mRNA CTD PMID:18032389 quercetin 3-O-beta-D-glucopyranoside multiple interactions ISO LDLR (Homo sapiens) 6480464 [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of LDLR mRNA CTD PMID:18032389 raloxifene increases expression ISO LDLR (Homo sapiens) 6480464 Raloxifene Hydrochloride results in increased expression of LDLR mRNA CTD PMID:16497877 rebaudioside A multiple interactions ISO Ldlr (Mus musculus) 6480464 rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA] more ... CTD PMID:25554529 resveratrol multiple interactions ISO LDLR (Homo sapiens) 6480464 25-hydroxycholesterol inhibits the reaction [[resveratrol results in increased activity of and results in increased cleavage of SREBF2 protein] which results in increased expression of LDLR mRNA] more ... CTD PMID:22153697 resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in decreased expression of LDLR mRNA] and resveratrol inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in decreased expression of LDLR protein] CTD PMID:23127599 resveratrol increases expression ISO LDLR (Homo sapiens) 6480464 resveratrol results in increased expression of LDLR mRNA CTD PMID:22153697 resveratrol decreases N-linked glycosylation ISO LDLR (Homo sapiens) 6480464 resveratrol results in decreased N-linked glycosylation of LDLR protein CTD PMID:22153697 resveratrol increases O-linked glycosylation ISO LDLR (Homo sapiens) 6480464 resveratrol results in increased O-linked glycosylation of LDLR protein CTD PMID:22153697 rifampicin increases expression ISO Ldlr (Mus musculus) 6480464 Rifampin results in increased expression of LDLR mRNA CTD PMID:27806127 risperidone multiple interactions ISO Ldlr (Mus musculus) 6480464 Berberine inhibits the reaction [Risperidone results in increased expression of LDLR mRNA] CTD PMID:20564506 risperidone increases expression ISO Ldlr (Mus musculus) 6480464 Risperidone results in increased expression of LDLR mRNA CTD PMID:20564506 rotenone affects expression EXP 6480464 Rotenone affects the expression of LDLR mRNA CTD PMID:28374803 rottlerin multiple interactions EXP 6480464 rottlerin inhibits the reaction [PRKCD protein promotes the reaction [Lead results in increased localization of LDLR protein]] CTD PMID:20488202 SB 431542 multiple interactions ISO LDLR (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LDLR mRNA CTD PMID:27188386 selenium atom multiple interactions EXP 6480464 Selenium inhibits the reaction [Cholesterol results in decreased activity of LDLR protein] and Selenium inhibits the reaction [Cholesterol results in decreased expression of LDLR mRNA] CTD PMID:16937255 selenium atom multiple interactions ISO Ldlr (Mus musculus) 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA] CTD PMID:36464106 selenium atom increases expression EXP 6480464 Selenium results in increased expression of LDLR mRNA CTD PMID:16271152 selenium atom increases activity EXP 6480464 Selenium results in increased activity of LDLR protein CTD PMID:16271152 selenium atom decreases activity EXP 6480464 Selenium deficiency results in decreased activity of LDLR protein CTD PMID:16317514 selenium atom decreases expression EXP 6480464 Selenium deficiency results in decreased expression of LDLR mRNA CTD PMID:16317514 silicon dioxide affects expression ISO LDLR (Homo sapiens) 6480464 Silicon Dioxide analog affects the expression of LDLR mRNA CTD PMID:23806026 silicon dioxide increases expression ISO LDLR (Homo sapiens) 6480464 Silicon Dioxide results in increased expression of LDLR mRNA CTD PMID:25351596 silver atom increases expression ISO LDLR (Homo sapiens) 6480464 Silver results in increased expression of LDLR mRNA CTD PMID:26014281 silver(0) increases expression ISO LDLR (Homo sapiens) 6480464 Silver results in increased expression of LDLR mRNA CTD PMID:26014281 simvastatin multiple interactions ISO LDLR (Homo sapiens) 6480464 [LDLR 3' UTR polymorphism affects the susceptibility to Simvastatin] which affects the expression of APOB more ... CTD PMID:17980884 and PMID:20413733 simvastatin increases expression ISO LDLR (Homo sapiens) 6480464 Simvastatin results in increased expression of LDLR mRNA and Simvastatin results in increased expression of LDLR protein CTD PMID:10357840 more ... simvastatin increases activity ISO LDLR (Homo sapiens) 6480464 Simvastatin results in increased activity of LDLR protein CTD PMID:11728391 and PMID:8593127 simvastatin increases expression EXP 6480464 Simvastatin results in increased expression of LDLR mRNA CTD PMID:18640378 simvastatin multiple interactions EXP 6480464 Berberine promotes the reaction [Simvastatin results in increased expression of LDLR mRNA] and Simvastatin promotes the reaction [Berberine results in increased expression of LDLR mRNA] CTD PMID:18640378 simvastatin increases expression ISO Ldlr (Mus musculus) 6480464 Simvastatin results in increased expression of LDLR mRNA CTD PMID:22120639 simvastatin affects response to substance ISO LDLR (Homo sapiens) 6480464 LDLR 3' UTR polymorphism affects the susceptibility to Simvastatin and LDLR mutant form affects the susceptibility to Simvastatin CTD PMID:10208479 more ... sodium arsenate multiple interactions ISO Ldlr (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of LDLR mRNA CTD PMID:34876320 sodium arsenite increases expression ISO LDLR (Homo sapiens) 6480464 sodium arsenite results in increased expression of LDLR mRNA CTD PMID:25524072 more ... sodium arsenite multiple interactions ISO Ldlr (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of LDLR mRNA CTD PMID:34876320 sotorasib multiple interactions ISO LDLR (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LDLR mRNA CTD PMID:36139627 steviol multiple interactions ISO Ldlr (Mus musculus) 6480464 steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACACA mRNA] more ... CTD PMID:25554529 stevioside multiple interactions ISO Ldlr (Mus musculus) 6480464 stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA] more ... CTD PMID:25554529 streptozocin decreases expression ISO Ldlr (Mus musculus) 6480464 Streptozocin results in decreased expression of LDLR mRNA CTD PMID:34896238 streptozocin multiple interactions ISO Ldlr (Mus musculus) 6480464 [Dietary Fats co-treated with Streptozocin] results in decreased expression of LDLR mRNA more ... CTD PMID:33359794 and PMID:34896238 sucrose multiple interactions EXP 6480464 [Sucrose co-treated with Dietary Fats] results in decreased expression of LDLR mRNA more ... CTD PMID:23127599 sulindac sulfide decreases expression ISO LDLR (Homo sapiens) 6480464 sulindac sulfide results in decreased expression of LDLR mRNA CTD PMID:16184548 sunitinib increases expression ISO LDLR (Homo sapiens) 6480464 Sunitinib results in increased expression of LDLR mRNA CTD PMID:31533062 tamoxifen increases expression ISO LDLR (Homo sapiens) 6480464 Tamoxifen results in increased expression of LDLR protein CTD PMID:27358406 tamoxifen increases expression ISO Ldlr (Mus musculus) 6480464 Tamoxifen results in increased expression of LDLR mRNA and Tamoxifen results in increased expression of LDLR protein CTD PMID:35944649 tamoxifen multiple interactions ISO Ldlr (Mus musculus) 6480464 SREBF2 protein promotes the reaction [Tamoxifen results in increased expression of LDLR mRNA] and SREBF2 protein promotes the reaction [Tamoxifen results in increased expression of LDLR protein] CTD PMID:35944649 tert-butyl hydroperoxide increases expression ISO LDLR (Homo sapiens) 6480464 tert-Butylhydroperoxide results in increased expression of LDLR mRNA CTD PMID:12414654 tetrachloromethane decreases expression ISO Ldlr (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of LDLR mRNA CTD PMID:31919559 thapsigargin decreases expression ISO LDLR (Homo sapiens) 6480464 Thapsigargin results in decreased expression of LDLR mRNA CTD PMID:22378314 thapsigargin increases expression EXP 6480464 Thapsigargin results in increased expression of LDLR protein CTD PMID:35544339 thapsigargin increases expression ISO LDLR (Homo sapiens) 6480464 Thapsigargin results in increased expression of LDLR mRNA CTD PMID:29453283 thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of LDLR mRNA CTD PMID:34492290 titanium dioxide increases expression ISO Ldlr (Mus musculus) 6480464 titanium dioxide results in increased expression of LDLR mRNA CTD PMID:23557971 more ... trametinib multiple interactions ISO LDLR (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LDLR mRNA CTD PMID:36139627 triadimefon affects expression ISO Ldlr (Mus musculus) 6480464 triadimefon affects the expression of LDLR mRNA CTD PMID:21195148 triadimefon decreases expression EXP 6480464 triadimefon results in decreased expression of LDLR mRNA CTD PMID:36179991 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of LDLR mRNA CTD PMID:33387578 triclosan decreases expression ISO LDLR (Homo sapiens) 6480464 Triclosan results in decreased expression of LDLR mRNA CTD PMID:34681664 triphenyl phosphate increases expression ISO Ldlr (Mus musculus) 6480464 triphenyl phosphate results in increased expression of LDLR mRNA CTD PMID:26049154 triphenyl phosphate decreases expression ISO Ldlr (Mus musculus) 6480464 triphenyl phosphate results in decreased expression of LDLR mRNA CTD PMID:26183808 triphenyl phosphate increases expression ISO LDLR (Homo sapiens) 6480464 triphenyl phosphate results in increased expression of LDLR mRNA CTD PMID:28934090 triphenylstannane decreases expression EXP 6480464 triphenyltin results in decreased expression of LDLR mRNA and triphenyltin results in decreased expression of LDLR protein CTD PMID:32504733 triptonide decreases expression ISO Ldlr (Mus musculus) 6480464 triptonide results in decreased expression of LDLR mRNA CTD PMID:33045310 tris(2-chloroethyl) phosphate increases expression ISO Ldlr (Mus musculus) 6480464 tris(chloroethyl)phosphate results in increased expression of LDLR mRNA CTD PMID:26049154 tris(2-chloroethyl) phosphate decreases expression ISO Ldlr (Mus musculus) 6480464 tris(chloroethyl)phosphate results in decreased expression of LDLR mRNA CTD PMID:26183808 troglitazone multiple interactions ISO LDLR (Homo sapiens) 6480464 [[troglitazone binds to and results in increased activity of PPARG protein] which results in decreased expression of SREBF2 protein] which results in decreased expression of LDLR mRNA CTD PMID:16946405 troglitazone decreases expression ISO LDLR (Homo sapiens) 6480464 troglitazone results in decreased expression of LDLR mRNA CTD PMID:25572481 troglitazone increases activity ISO LDLR (Homo sapiens) 6480464 troglitazone results in increased activity of LDLR protein CTD PMID:9703316 troglitazone increases expression ISO LDLR (Homo sapiens) 6480464 troglitazone results in increased expression of LDLR mRNA CTD PMID:9703316 trovafloxacin multiple interactions ISO Ldlr (Mus musculus) 6480464 [trovafloxacin co-treated with lipopolysaccharide and E coli O55-B5] results in decreased expression of LDLR mRNA CTD PMID:18930950 tunicamycin decreases expression ISO LDLR (Homo sapiens) 6480464 Tunicamycin results in decreased expression of LDLR mRNA CTD PMID:22378314 and PMID:29453283 urethane increases expression ISO LDLR (Homo sapiens) 6480464 Urethane results in increased expression of LDLR mRNA CTD PMID:28818685 valproic acid affects expression ISO Ldlr (Mus musculus) 6480464 Valproic Acid affects the expression of LDLR mRNA CTD PMID:17963808 valproic acid affects methylation ISO LDLR (Homo sapiens) 6480464 Valproic Acid affects the methylation of LDLR gene CTD PMID:29501571 valproic acid decreases expression ISO LDLR (Homo sapiens) 6480464 Valproic Acid results in decreased expression of LDLR mRNA CTD PMID:23179753 more ... valproic acid affects expression ISO LDLR (Homo sapiens) 6480464 Valproic Acid affects the expression of LDLR mRNA CTD PMID:25979313 valproic acid decreases expression ISO Ldlr (Mus musculus) 6480464 Valproic Acid results in decreased expression of LDLR mRNA CTD PMID:19136453 and PMID:22045034 vancomycin multiple interactions ISO Ldlr (Mus musculus) 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA] and [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA CTD PMID:36464106 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of LDLR mRNA CTD PMID:23034163 vorinostat decreases expression ISO LDLR (Homo sapiens) 6480464 vorinostat results in decreased expression of LDLR mRNA CTD PMID:27188386 Yessotoxin increases expression ISO LDLR (Homo sapiens) 6480464 yessotoxin analog results in increased expression of LDLR mRNA CTD PMID:30679557 zearalenone increases expression ISO LDLR (Homo sapiens) 6480464 Zearalenone results in increased expression of LDLR mRNA CTD PMID:32119988 zearalenone decreases expression EXP 6480464 Zearalenone results in decreased expression of LDLR mRNA and Zearalenone results in decreased expression of LDLR protein CTD PMID:32858132 zinc atom multiple interactions ISO LDLR (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of LDLR mRNA CTD PMID:18593933 zinc atom increases response to substance ISO Ldlr (Mus musculus) 6480464 LDLR gene mutant form results in increased susceptibility to Zinc deficiency CTD PMID:16140885 zinc atom multiple interactions ISO Ldlr (Mus musculus) 6480464 [LDLR gene mutant form results in increased susceptibility to Zinc deficiency] which results in increased expression of PPARG mRNA more ... CTD PMID:16140885 zinc(0) multiple interactions ISO LDLR (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of LDLR mRNA CTD PMID:18593933 zinc(0) increases response to substance ISO Ldlr (Mus musculus) 6480464 LDLR gene mutant form results in increased susceptibility to Zinc deficiency CTD PMID:16140885 zinc(0) multiple interactions ISO Ldlr (Mus musculus) 6480464 [LDLR gene mutant form results in increased susceptibility to Zinc deficiency] which results in increased expression of PPARG mRNA more ... CTD PMID:16140885 zoledronic acid increases expression ISO LDLR (Homo sapiens) 6480464 zoledronic acid results in increased expression of LDLR mRNA CTD PMID:20977926
