Gene: Abcc8 (ATP binding cassette subfamily C member 8) Rattus norvegicus
Symbol: Abcc8
Name: ATP binding cassette subfamily C member 8
Description: ENCODES a protein that exhibits ATP binding; potassium channel activity; syntaxin binding; INVOLVED IN cellular response to organic substance; negative regulation of insulin secretion; positive regulation of potassium ion transport; PARTICIPATES IN diabetes pathway; acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; ASSOCIATED WITH Brain Edema; Endotoxemia; Hypoglycemia; FOUND IN sarcolemma; synaptic vesicle membrane; plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
Also known as: ATP-binding cassette sub-family C (CFTR/MRP) member 8; ATP-binding cassette sub-family C member 8; ATP-binding cassette subfamily C (CFTR/MRP) member 8; ATP-binding cassette transporter sub-family C member 8; ATP-binding cassette, sub-family C (CFTR/MRP), member 8; ATP-binding cassette, subfamily C (CFTR/MRP), member 8; sulfonylurea receptor; sulfonylurea receptor 1; sulphonylurea receptor 1; Sur; Sur1
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01102,110,708 - 102,191,287 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01103,194,473 - 103,275,508 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4196,622,574 - 96,703,723 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1196,700,590 - 96,781,880 (-)NCBI
Celera190,849,685 - 90,928,224 (-)NCBI
Cytogenetic Map1q22NCBImapview

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Abcc8
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 3786
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-10-04
Status: ACTIVE