Gene: Abcc8 (ATP binding cassette subfamily C member 8) Rattus norvegicus
Symbol: Abcc8
Name: ATP binding cassette subfamily C member 8
Description: ENCODES a protein that exhibits ATP binding; potassium channel activity; syntaxin binding; INVOLVED IN cellular response to organic substance; negative regulation of insulin secretion; positive regulation of potassium ion transport; PARTICIPATES IN diabetes pathway; acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; ASSOCIATED WITH Brain Edema; Endotoxemia; Hypoglycemia; FOUND IN sarcolemma; synaptic vesicle membrane; plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ATP-binding cassette sub-family C (CFTR/MRP) member 8; ATP-binding cassette sub-family C member 8; ATP-binding cassette subfamily C (CFTR/MRP) member 8; ATP-binding cassette transporter sub-family C member 8; ATP-binding cassette, sub-family C (CFTR/MRP), member 8; ATP-binding cassette, subfamily C (CFTR/MRP), member 8; sulfonylurea receptor; sulfonylurea receptor 1; sulphonylurea receptor 1; Sur; Sur1
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01102,110,436 - 102,191,359 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01103,194,473 - 103,275,508 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4196,622,574 - 96,703,723 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1196,700,590 - 96,781,880 (-)NCBI
Celera190,849,685 - 90,928,224 (-)NCBI
Cytogenetic Map1q22NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Abcc8
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 3786
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-04-12
Status: ACTIVE