Egln1 (EGL nine homolog 1 (C. elegans))

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Keyword

Gene: Egln1 (EGL nine homolog 1 (C. elegans)) Rattus norvegicus

Symbol:

Egln1

Name:

EGL nine homolog 1 (C. elegans)

Description:

ENCODES a protein that exhibits peptidyl-proline dioxygenase activity; peptidyl-proline 4-dioxygenase activity (ortholog); INVOLVED IN negative regulation of sequence-specific DNA binding transcription factor activity; response to hypoxia; cardiac muscle tissue morphogenesis (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; vascular endothelial growth factor signaling pathway; renal cell cancer pathway; ASSOCIATED WITH Erythrocytosis, Familial, 3 (ortholog); FOUND IN cytosol; cytoplasm (ortholog); INTERACTS WITH 2,6-dinitrotoluene; ammonium chloride; astemizole

Type:

protein-coding

RefSeq Status:

MODEL

Also known as:

egl nine homolog 1; HIF-PH2; HIF-prolyl hydroxylase 2; HPH-2; hypoxia-inducible factor prolyl hydroxylase 2; PHD-2; PHD2; prolyl hydroxylase domain-containing protein 2

Orthologs:

Homo sapiens : EGLN1 (egl nine homolog 1 (C. elegans)) HGNC
Mus musculus : Egln1 (EGL nine homolog 1 (C. elegans)) MGI

Latest Assembly:

RGSC Genome Assembly v3.4

NCBI Annotation Information:

Annotation category: suggests misassembly; Annotation category: partial on reference assembly

Position:

Map	Chr	Position	Strand	Source
Rat Cytogenetic Map	19	q12		NCBI
RGSC Genome Assembly v5.0	19	68,373,433 - 68,413,328	-	NCBI
RGSC Genome Assembly v3.4	19	55,080,670 - 55,118,226	-	NCBI
Rat Celera Assembly	19	52,235,066 - 52,273,833	-	NCBI
Genome Assembly 3.1	19	55,086,125 - 55,122,813	-	NCBI