Gene: Pcsk1 (proprotein convertase subtilisin/kexin type 1) Rattus norvegicus
Symbol: Pcsk1
Name: proprotein convertase subtilisin/kexin type 1
Description: ENCODES a protein that exhibits chaperone binding; endopeptidase activity; insulin binding; INVOLVED IN neurogenesis; pancreas development; peptide hormone processing; PARTICIPATES IN altered energy homeostasis pathway; altered melanocortin system pathway; melanocortin system pathway; ASSOCIATED WITH Adenoma, Islet Cell; Dehydration; Diabetes Mellitus, Experimental; FOUND IN axon terminus; dendrite; extracellular space; INTERACTS WITH (+)-pilocarpine; 1,3-dinitrobenzene; 17alpha-ethynylestradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BDP; NEC 1; neuroendocrine convertase 1; PC1; PC3; prohormone convertase 1; prohormone convertase 3; proprotein convertase 1; Protein convertase subtilisin / kexin type I; Protein convertase subtilisin / kexin, type I
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.0291,450,162 - 91,497,091-NCBI
Rat Cytogenetic Map2q11-q12 NCBI
RGSC Genome Assembly v5.022,274,882 - 2,309,886+NCBI
RGSC Genome Assembly v3.421,923,309 - 1,970,238+NCBI
Rat Celera Assembly2885,989 - 932,918+NCBI
Genome Assembly 3.121,937,434 - 1,981,975+NCBI

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Disease Annotations
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Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Pcsk1
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RGD Object Information
RGD ID: 3272
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-02-02
Status: ACTIVE