Gene: Pcsk1 (proprotein convertase subtilisin/kexin type 1) Rattus norvegicus
Symbol: Pcsk1
Name: proprotein convertase subtilisin/kexin type 1
Description: ENCODES a protein that exhibits chaperone binding; endopeptidase activity; insulin binding; INVOLVED IN neurogenesis; pancreas development; peptide hormone processing; PARTICIPATES IN altered energy homeostasis pathway; altered melanocortin system pathway; melanocortin system pathway; ASSOCIATED WITH Adenoma, Islet Cell; Dehydration; Diabetes Mellitus, Experimental; FOUND IN axon terminus; dendrite; extracellular space; INTERACTS WITH (+)-pilocarpine; 1,3-dinitrobenzene; 17alpha-ethynylestradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BDP; NEC 1; neuroendocrine convertase 1; PC1; PC3; prohormone convertase 1; prohormone convertase 3; proprotein convertase 1; Protein convertase subtilisin / kexin type I; Protein convertase subtilisin / kexin, type I
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0291,450,162 - 91,497,091 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.022,274,882 - 2,309,886 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.421,923,309 - 1,970,238 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.121,937,434 - 1,981,975 (+)NCBI
Celera2885,989 - 932,918 (+)NCBI
Cytogenetic Map2q11-q12NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pcsk1
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 3272
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-08-02
Status: ACTIVE