Gene: Actn4 (actinin alpha 4) Rattus norvegicus
Symbol: Actn4
Name: actinin alpha 4
Description: ENCODES a protein that exhibits protein complex binding; protein N-terminus binding; actin filament binding (ortholog); INVOLVED IN regulation of apoptotic process; response to hypoxia; actin filament bundle assembly (ortholog); PARTICIPATES IN platelet-derived growth factor signaling pathway; arrhythmogenic right ventricular cardiomyopathy pathway; Entamoeba histolyca infection pathway; ASSOCIATED WITH Carcinoma (ortholog); Glomerulosclerosis, Focal Segmental (ortholog); Mammary Neoplasms, Animal (ortholog); FOUND IN cytoplasm; neuron projection; nucleus; INTERACTS WITH 2,2,2-tetramine; 2,6-dinitrotoluene; 2-nitrotoluene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha actinin 4; alpha actinin 4 between D1Rat178 and D1Rat97; alpha-actinin-4; F-actin cross-linking protein; non-muscle alpha-actinin 4
Homo sapiens (human) : ACTN4 (actinin alpha 4)  HGNC  AGR
Mus musculus (house mouse) : Actn4 (actinin alpha 4)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Actn4 (actinin alpha 4)
Pan paniscus (bonobo/pygmy chimpanzee) : ACTN4 (actinin alpha 4)
Canis lupus familiaris (dog) : ACTN4 (actinin alpha 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Actn4 (actinin alpha 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0187,078,012 - 87,147,347 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0188,258,630 - 88,327,965 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4184,000,723 - 84,073,767 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1184,079,711 - 84,151,876 (-)NCBI
Celera178,572,890 - 78,641,919 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Actn4
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61816
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE