Fgr (FGR proto-oncogene, Src family tyrosine kinase)

Gene: Fgr (FGR proto-oncogene, Src family tyrosine kinase) Rattus norvegicus

Analyze

Symbol:

Fgr

Name:

FGR proto-oncogene, Src family tyrosine kinase

RGD ID:

621319

Description:

Enables protein tyrosine kinase activity. Involved in myoblast proliferation. Predicted to be located in aggresome and plasma membrane. Predicted to colocalize with actin cytoskeleton and ruffle membrane. Orthologous to human FGR (FGR proto-oncogene, Src family tyrosine kinase); PARTICIPATES IN eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; glypican signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

feline Gardner-Rasheed sarcoma viral oncogene; Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog; p55-Fgr; proto-oncogene c-Fgr; proto-oncogene tyrosine-protein kinase Fgr; tyrosine-protein kinase Fgr

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	150,473,767 - 150,503,524 (+)	NCBI		GRCr8
mRatBN7.2	5	145,189,814 - 145,219,571 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	145,189,841 - 145,217,326 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	147,889,803 - 147,917,343 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	149,659,399 - 149,686,941 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	149,647,808 - 149,675,309 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	151,172,189 - 151,199,746 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	151,172,206 - 151,199,745 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	154,839,086 - 154,866,424 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	152,119,455 - 152,147,057 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	152,129,494 - 152,157,096 (-)	NCBI
Celera	5	143,612,003 - 143,639,441 (+)	NCBI		Celera
RH 3.4 Map	5	977.8	RGD
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (ISO)

1-naphthyl isothiocyanate (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (EXP)

4-hydroxynon-2-enal (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acetylsalicylic acid (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

antirheumatic drug (ISO)

arsenous acid (ISO)

benzalkonium chloride (ISO)

benzo[a]pyrene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP,ISO)

bosutinib (EXP)

bromobenzene (EXP)

buta-1,3-diene (ISO)

butan-1-ol (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

chloroprene (EXP,ISO)

chlorpromazine (EXP)

cisplatin (ISO)

Cuprizon (EXP)

cyclosporin A (EXP)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dichlorine (EXP)

diethyl maleate (EXP)

diethylstilbestrol (ISO)

Dihydrocytochalasin B (ISO)

dimethylarsinic acid (ISO)

dioxygen (EXP)

endosulfan (EXP)

fenofibrate (EXP)

genistein (ISO)

hypochlorous acid (ISO)

indometacin (ISO)

leflunomide (EXP)

lipopolysaccharide (ISO)

metformin (EXP)

methylarsonic acid (ISO)

Muraglitazar (EXP)

N-formyl-L-methionyl-L-leucyl-L-phenylalanine (ISO)

N-nitrosodimethylamine (EXP)

nickel atom (ISO)

nickel dichloride (EXP)

ozone (EXP)

paracetamol (EXP,ISO)

perfluorooctanoic acid (EXP)

phosphatidic acid (ISO)

ponatinib (ISO)

resveratrol (EXP)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

tamibarotene (ISO)

Tesaglitazar (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

triptonide (ISO)

troglitazone (ISO)

tungsten (ISO)

valproic acid (ISO)

vincristine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

bone mineralization (ISO)

cell differentiation (IBA)

cell surface receptor protein tyrosine kinase signaling pathway (IBA)

defense response to Gram-positive bacterium (ISO,ISS)

innate immune response (IBA)

integrin-mediated signaling pathway (IBA,ISO,ISS)

myoblast proliferation (IEP)

negative regulation of natural killer cell activation (ISO)

positive regulation of cell migration (ISO,ISS)

positive regulation of cytokine production (ISO,ISS)

positive regulation of mast cell degranulation (ISO,ISS)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ISO)

regulation of cell shape (ISO,ISS)

regulation of innate immune response (ISO,ISS)

regulation of phagocytosis (ISO,ISS)

skeletal system morphogenesis (ISO)

Cellular Component

actin cytoskeleton (ISO,ISS)

aggresome (IEA,ISO)

cytoskeleton (ISO)

cytosol (IEA)

extrinsic component of cytoplasmic side of plasma membrane (IEA)

mitochondrial inner membrane (IEA)

mitochondrial intermembrane space (IEA)

plasma membrane (IBA,ISO)

ruffle membrane (ISO,ISS)

Molecular Function

ATP binding (IEA)

Fc-gamma receptor I complex binding (ISO)

immunoglobulin receptor binding (ISO,ISS)

non-membrane spanning protein tyrosine kinase activity (IBA,ISO)

phosphotyrosine residue binding (ISO,ISS)

protein binding (IPI,ISO)

protein kinase binding (ISO,ISS)

protein tyrosine kinase activity (IDA,ISO)

signaling receptor binding (IBA)

Molecular Pathway Annotations Click to see Annotation Detail View

chemokine mediated signaling pathway (IEA)

eicosanoid signaling pathway (ISO)

ephrin - ephrin receptor bidirectional signaling axis (ISO)

glypican signaling pathway (ISO)

phosphatidylinositol 3-kinase class I signaling pathway (ISO)

platelet-derived growth factor signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Hierarchical phosphorylation of a 50-kDa protein by protein tyrosine kinases TPK-IIB and C-Fgr, and its identification as HS1 hematopoietic-lineage cell-specific protein.	Brunati AM, etal., Eur J Biochem. 1995 Apr 1;229(1):164-70.
2.	Activation of RBL-2H3 mast cells is dependent on tyrosine phosphorylation of phospholipase D2 by Fyn and Fgr.	Choi WS, etal., Mol Cell Biol 2004 Aug;24(16):6980-92.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
5.	High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.	Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
6.	Differential expression of protooncogenes related to transformation and cancer progression in rat myoblasts.	Leibovitch SA, etal., Cancer Res. 1986 Aug;46(8):4097-103.
7.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
8.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
9.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
10.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
11.	GOA pipeline	RGD automated data pipeline
12.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
14.	Comprehensive gene review and curation	RGD comprehensive gene curation
15.	The Src family kinases, Fgr, Fyn, Lck, and Lyn, colocalize with coated membranes in platelets.	Stenberg PE, etal., Blood. 1997 Apr 1;89(7):2384-93.
16.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:2181286	PMID:7519620	PMID:8125254	PMID:8327512	PMID:8402898	PMID:8603737	PMID:10739672	PMID:10861086	PMID:11672534	PMID:11744621	PMID:15561106	PMID:16439675
PMID:16921024	PMID:16964445	PMID:20458337	PMID:20624904	PMID:21746961	PMID:22871113	PMID:30352950

Genomics

Comparative Map Data

Fgr
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	150,473,767 - 150,503,524 (+)	NCBI		GRCr8
mRatBN7.2	5	145,189,814 - 145,219,571 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	145,189,841 - 145,217,326 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	147,889,803 - 147,917,343 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	149,659,399 - 149,686,941 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	149,647,808 - 149,675,309 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	151,172,189 - 151,199,746 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	151,172,206 - 151,199,745 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	154,839,086 - 154,866,424 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	152,119,455 - 152,147,057 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	152,129,494 - 152,157,096 (-)	NCBI
Celera	5	143,612,003 - 143,639,441 (+)	NCBI		Celera
RH 3.4 Map	5	977.8	RGD
Cytogenetic Map	5	q36	NCBI

FGR
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	27,612,064 - 27,635,185 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	27,612,064 - 27,635,185 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	27,938,575 - 27,961,696 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	27,811,387 - 27,834,314 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	27,622,952 - 27,634,715	NCBI
Celera	1	26,334,465 - 26,357,390 (-)	NCBI		Celera
Cytogenetic Map	1	p35.3	NCBI
HuRef	1	26,195,016 - 26,217,930 (-)	NCBI		HuRef
CHM1_1	1	28,054,060 - 28,076,993 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	27,453,366 - 27,476,486 (-)	NCBI		T2T-CHM13v2.0

Fgr
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	132,701,406 - 132,729,204 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	132,701,406 - 132,729,221 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	132,974,095 - 133,001,893 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	132,974,095 - 133,001,910 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	132,530,010 - 132,557,808 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	132,246,204 - 132,273,882 (+)	NCBI		MGSCv36	mm8
Celera	4	131,136,566 - 131,164,622 (+)	NCBI		Celera
Cytogenetic Map	4	D2.3	NCBI
cM Map	4	66.11	NCBI

Fgr
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	6,841,802 - 6,863,542 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	6,840,274 - 6,863,460 (-)	NCBI	ChiLan1.0	ChiLan1.0

FGR
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	199,218,002 - 199,240,963 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	198,334,434 - 198,358,178 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	26,872,781 - 26,895,751 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	27,918,758 - 27,941,678 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	27,918,758 - 27,941,678 (-)	Ensembl	panpan1.1		panPan2

FGR
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	72,678,858 - 72,692,417 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	72,680,675 - 72,690,251 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	69,248,647 - 69,270,097 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	73,232,619 - 73,254,079 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	73,240,640 - 73,251,913 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	70,059,023 - 70,080,473 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	71,070,351 - 71,091,778 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	72,066,735 - 72,088,165 (+)	NCBI		UU_Cfam_GSD_1.0

Fgr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	46,072,309 - 46,094,439 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	11,896,914 - 11,919,190 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	11,897,998 - 11,919,153 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FGR
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	84,809,542 - 84,830,361 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	84,809,534 - 84,830,401 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	78,326,176 - 78,358,345 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FGR
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	105,155,223 - 105,178,813 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	105,165,043 - 105,179,067 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	11,285,735 - 11,309,416 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fgr
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	11,489,685 - 11,513,270 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	11,482,719 - 11,513,215 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Fgr
191 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	331
Count of miRNA genes:	195
Interacting mature miRNAs:	225
Transcripts:	ENSRNOT00000013778
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40128307	148607290	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	46711509	161317411	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	60293434	161481680	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	69540295	151018848	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	82394392	166664054	Rat
1331796	Thshl2	Thyroid stimulating hormone level QTL 2	2.3		blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	5	97059760	147465714	Rat
1358187	Emca1	Estrogen-induced mammary cancer QTL 1	4.4		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	5	99216724	148607142	Rat
1578673	Bmd13	Bone mineral density QTL 13	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	5	103689353	148689353	Rat
2317056	Wbc3	White blood cell count QTL 3	2.51	0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	5	105999803	150999803	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	106906205	151906205	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	106906205	151906205	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	106906205	151906205	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	106906205	151906205	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	106906205	151906205	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	108845856	153845856	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	108845856	153845856	Rat
8657050	Bw146	Body weight QTL 146	19.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	108938288	153938288	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	111416838	156416838	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	111416838	156416838	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	111416838	156416838	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	111416838	156416838	Rat
2293642	Bss37	Bone structure and strength QTL 37	4.64	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	120740824	151018848	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	121846814	166846814	Rat
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	124965598	166875058	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	126424772	166875058	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	127798274	166875058	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	127798274	166875058	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	128506074	166875058	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	128506074	166875058	Rat
634349	Bp139	Blood pressure QTL 139		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	128924607	166875058	Rat
70156	Niddm30	Non-insulin dependent diabetes mellitus QTL 30	3.98		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	5	129132447	151006154	Rat
738018	Anxrr4	Anxiety related response QTL 4	5.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	5	130130159	166875058	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	131345754	166875058	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	132717196	165560427	Rat
631562	Apr2	Acute phase response QTL 2	3.7		blood murinoglobulin 1 amount (VT:0010597)	plasma murinoglobulin 1 level (CMO:0001931)	5	135927956	166875058	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	135929696	166875058	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	143069996	166846814	Rat
2302369	Scl60	Serum cholesterol level QTL 60	3.13		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	143608201	161165651	Rat
631263	Cm24	Cardiac mass QTL 24	3.5		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	143799107	158428037	Rat
1300119	Bp180	Blood pressure QTL 180	3.82		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	144358090	157869054	Rat
2313096	Bmd78	Bone mineral density QTL 78	3.1	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	5	144377876	161317411	Rat

Markers in Region

D5Got83

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	145,205,556 - 145,205,750 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	151,187,978 - 151,188,171	NCBI	Rnor6.0
Rnor_5.0	5	154,854,649 - 154,854,842	UniSTS	Rnor5.0
RGSC_v3.4	5	152,131,030 - 152,131,224	RGD	RGSC3.4
RGSC_v3.4	5	152,131,031 - 152,131,224	UniSTS	RGSC3.4
RGSC_v3.1	5	152,141,070 - 152,141,263	RGD
Celera	5	143,627,672 - 143,627,865	UniSTS
RH 3.4 Map	5	989.2	RGD
RH 3.4 Map	5	989.2	UniSTS
Cytogenetic Map	5	q36	UniSTS

RH142441

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	145,216,800 - 145,216,950 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	151,199,220 - 151,199,369	NCBI	Rnor6.0
Rnor_5.0	5	154,865,891 - 154,866,040	UniSTS	Rnor5.0
RGSC_v3.4	5	152,119,832 - 152,119,981	UniSTS	RGSC3.4
Celera	5	143,638,915 - 143,639,064	UniSTS
RH 3.4 Map	5	977.8	UniSTS
Cytogenetic Map	5	q36	UniSTS

RH141155

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	145,216,742 - 145,216,933 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	151,199,162 - 151,199,352	NCBI	Rnor6.0
Rnor_5.0	5	154,865,833 - 154,866,023	UniSTS	Rnor5.0
RGSC_v3.4	5	152,119,849 - 152,120,039	UniSTS	RGSC3.4
Celera	5	143,638,857 - 143,639,047	UniSTS
RH 3.4 Map	5	977.8	UniSTS
Cytogenetic Map	5	q36	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2				11						1	11
Low	1	27	57	41	8	41	6	9	31	33	39		6
Below cutoff		16					2	2	43	2	1		2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_024145	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239079	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239081	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239082	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110824	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110825	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110826	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110827	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110829	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063288461	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC062025	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ234703	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X57018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000013778 ⟹ ENSRNOP00000013779

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	145,189,841 - 145,217,326 (+)	Ensembl
Rnor_6.0 Ensembl	5	151,172,206 - 151,199,745 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000085674 ⟹ ENSRNOP00000075272

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	5	151,181,559 - 151,199,500 (+)	Ensembl

RefSeq Acc Id:

NM_024145 ⟹ NP_077059

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	150,473,797 - 150,501,280 (+)	NCBI
mRatBN7.2	5	145,189,841 - 145,217,327 (+)	NCBI
Rnor_6.0	5	151,172,206 - 151,199,746 (+)	NCBI
Rnor_5.0	5	154,839,086 - 154,866,424 (+)	NCBI
RGSC_v3.4	5	152,119,455 - 152,147,057 (-)	RGD
Celera	5	143,612,003 - 143,639,441 (+)	RGD

Sequence:

show sequence

GGACAGGGGCGGGTAGCACTTCACTTTCCCCTCACATCGTTCCTGAAAATTAGGGTTGGCTCGC
CCCAGATCGGGTCACCAGCAGCTGGCTCCCTTGAGACCAGGTAGGCGGCCAAACCAGGAGGAGG
CTGACCCGGCAGGTGTCGCCCCGCCCCTGTCCGTCCTCGCCCTGGAAGGAAGATTTAGAGGTTT
CCGGCACCCCCCCCCCGCCCCCAGGGACCATGCATCAGTCCTACTGACCCAGGAGTAGGGGCCT
GTGGGCAGGACACCTGGAATGGGCTGTGTGTTCTGCAAGAAGTTAGAGCCTGCACCCAAGGAGG
ATGTTGGCCTGGAAGGGGACTTCCGGAGCCAAGGCGCTGAAGAACGCTATTACCCTGACCCTAC
TCAAGGCCGGTCTTCGTCCATCTCGCCTCAGCCCATCAGCCCTGCTTTCCTTAATGTTGGCAAC
ATAAGAAGCGTCTCTGGGACGGGAGTGACCATATTCGTCGCCCTGTATGACTATGAGGCCAGGA
CAGGGGATGACCTCACCTTCACCAAAGGCGAGAAGTTCCACATCCTGAACAATACGGAGTATGA
CTGGTGGGAGGCTAGGTCCCTGAGCTCCGGACGCACGGGCTATGTTCCCAGCAACTATGTGGCT
CCCGTGGATTCCATCCAGGCTGAAGAGTGGTACTTCGGAAAGATCAGCAGAAAGGATGCAGAGA
GGCAGCTTCTCTCCGATGGCAACCCTCAAGGGGCCTTTCTCATTCGGGAAAGCGAGACCACCAA
AGGTGCCTACTCCCTGTCCATCCGTGACTGGGACCAGAACAGAGGCGACCACATAAAGCATTAC
AAGATCCGAAAGCTGGACATGGGTGGCTACTACATCACCACGCGGGCCCAGTTCGAATCCGTGC
AGGACCTGGTGCGGCACTACATGGAAGTGAATGACGGTCTATGCTACTTGCTCACCGCACCCTG
TATGGTCATGAAGCCCCAGACTCTAGGCCTGGCTAAGGATGCCTGGGAGATCGACCGTAACTCC
ATAGCACTTGACCGCAGGCTGGGCACCGGCTGCTTTGGAGACGTGTGGCTGGGCACGTGGAACT
GTAGCACAAAGGTGGCAGTGAAAACGCTGAAGCCAGGCACCATGTCGCCGAAGGCCTTCCTGGA
GGAGGCACAGATCATGAAACTGCTGAGGCACGACAAGCTGGTGCAGCTGTACGCGGTGGTGTCA
GAGGAACCCATTTATATTGTGACAGAGTTCATGTGCTATGGTAGCTTGCTGGATTTCCTAAAGG
ATCGAAAGGGTCACAACTTGATGCTGCCCAATCTAGTGGACATGGCTGCCCAGGTAGCAGAGGG
CATGGCCTACATGGAGCGCATGAACTATATCCACCGAGACCTGAGAGCAGCCAACATCCTGGTG
GGGGAACATCTAATATGCAAGATCGCTGACTTTGGGTTGGCACGCCTCATAGTGGACGATGAGT
ACAACCCCCAACAAGGAACCAAGTTTCCCATCAAGTGGACAGCCCCAGAGGCTGCTCTCTTTGG
CAGATTCACTGTCAAATCAGACGTGTGGTCCTTTGGGATTCTGCTCACTGAACTGATCACCAAG
GGCAGAGTTCCATACCCAGGTATGAACAACCGGGAAGTGTTGGAACAGGTAGAGCACGGCTACC
ACATGCCATGCCCTCCGGGATGCCCAGTATCCCTGTATGAGGTCATGGAGCAGACCTGGCGTCT
GGATCCAGAGGAGAGGCCCACCTTTGAGTACCTGCAGTCTTTCCTGGAAGACTATTTCACCTCC
ACAGAACCACAGTATCAGCCCGGAGACCAGACATAGCCTGACTGGGTATCAGTGACCCTCTGAG
ACTATGTACTAACCCTTGCCAATCCCCAGGGCACTCTGGTCCCAGTGCCCCGAGACTTGGAACC
CTGTGGAATCCTAGCACGTCAGAAAAAGTCCGAAGCTCTGAAGCCATTTTATAGAGGGTGCAAA
TGGAGACTAGAAATTCATCTCTTACCTTCGCTGGCCCCAAGCACTCTTTCTTCCCTTCCCACCC
ATGCCCCATGCAAAAATCTAGGGCACCCAGTCATTTCACAGACGGAGTAAATGGATGCTCAGAG
TTCATCTCTCGTACACTCTGACCCCAGTACCATTTTTCCTGTCCCATTAGGCTCCTACGTACCG
TTAGTCCCCCCCCCATCTCCTAAAAATACTCATACATTGTGTAGTTATTTATAAAATTGTATTT
CTCTTCTTCCACTTACCTCTTATCCCTGCTTTCTAACCTCCTGTCAGCCCACTCCAGCCCAGAC
CCTAAGAGTTTAATTCTGAGGTTCTCTTGGGTTTCTCTACGTTACAAAGGCAGGGGACGTCTCT
GCTTGATTCCCCGTCTTCAGACTGGATGCTGTGGTCCAGGCCCAGGTCTGAAGGAGAGAGCCAT
TGAAGGCTCACCATCTCTCTGAGTGGTCTGAATGTGTTTATTCGTTATAAACGAACAGTGATGA
TCGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006239079 ⟹ XP_006239141

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	150,483,526 - 150,503,524 (+)	NCBI
mRatBN7.2	5	145,199,571 - 145,216,655 (+)	NCBI
Rnor_6.0	5	151,181,962 - 151,199,746 (+)	NCBI
Rnor_5.0	5	154,839,086 - 154,866,424 (+)	NCBI

Sequence:

show sequence

AGAACAGAGCTGCTGGGGAAAGTTTGGCTACTTCCCAGATCTCTTCAAGAGACTATAGTGGCCC
CAGCTTCTCCCTAACCCTGGTCTGTAGGAGACTGTCACTTTCATCCTGGCACAAGAGGTTTCCG
GCACCCCCCCCCGCCCCCAGGGACCATGCATCAGTCCTACTGACCCAGGAGTAGGGGCCTGTGG
GCAGGACACCTGGAATGGGCTGTGTGTTCTGCAAGAAGTTAGAGCCTGCACCCAAGGAGGATGT
TGGCCTGGAAGGGGACTTCCGGAGCCAAGGCGCTGAAGAACGCTATTACCCTGACCCTACTCAA
GGCCGGTCTTCGTCCATCTCGCCTCAGCCCATCAGCCCTGCTTTCCTTAATGTTGGCAACATAA
GAAGCGTCTCTGGGACGGGAGTGACCATATTCGTCGCCCTGTATGACTATGAGGCCAGGACAGG
GGATGACCTCACCTTCACCAAAGGCGAGAAGTTCCACATCCTGAACAATACGGAGTATGACTGG
TGGGAGGCTAGGTCCCTGAGCTCCGGACGCACGGGCTATGTTCCCAGCAACTATGTGGCTCCCG
TGGATTCCATCCAGGCTGAAGAGTGGTACTTCGGAAAGATCAGCAGAAAGGATGCAGAGAGGCA
GCTTCTCTCCGATGGCAACCCTCAAGGGGCCTTTCTCATTCGGGAAAGCGAGACCACCAAAGGT
GCCTACTCCCTGTCCATCCGTGACTGGGACCAGAACAGAGGCGACCACATAAAGCATTACAAGA
TCCGAAAGCTGGACATGGGTGGCTACTACATCACCACGCGGGCCCAGTTCGAATCCGTGCAGGA
CCTGGTGCGGCACTACATGGAAGTGAATGACGGTCTATGCTACTTGCTCACGGCACCCTGTATG
GTCATGAAGCCCCAGACTCTAGGCCTGGCTAAGGATGCCTGGGAGATCGACCGTAACTCCATAG
CACTTGACCGCAGGCTGGGCACCGGCTGCTTTGGAGACGTGTGGCTGGGCACGTGGAACTGTAG
CACAAAGGTGGCAGTGAAAACGCTGAAGCCAGGCACCATGTCGCCGAAGGCCTTCCTGGAGGAG
GCACAGATCATGAAACTGCTGAGGCACGACAAGCTGGTGCAGCTGTACGCGGTGGTGTCAGAGG
AACCCATTTATATTGTGACAGAGTTCATGTGCTATGGTAGCTTGCTGGATTTCCTAAAGGATCG
AAAGGGTCACAACTTGATGCTGCCCAATCTAGTGGACATGGCTGCCCAGGTAGCAGAGGGCATG
GCCTACATGGAGCGCATGAACTATATCCACCGAGACCTGAGAGCAGCCAACATCCTGGTGGGGG
AACATCTAATATGCAAGATCGCTGACTTTGGGTTGGCACGCCTCATAGTGGATGATGAGTACAA
CCCCCAACAAGGAACCAAGTTTCCCATCAAGTGGACAGCCCCAGAGGCTGCTCTCTTTGGCAGA
TTCACTGTCAAATCAGACGTGTGGTCCTTTGGGATTCTGCTCACTGAACTGATCACCAAGGGCA
GAGTTCCATACCCAGGTATGAACAACCGGGAAGTGTTGGAACAGGTAGAGCACGGCTACCACAT
GCCATGCCCTCCGGGATGCCCAGTATCCCTGTATGAGGTCATGGAGCAGACCTGGCGTCTGGAT
CCAGAGGAGAGGCCCACCTTTGAGTACCTGCAGTCTTTCCTGGAAGACTATTTCACCTCCACAG
AACCACAGTATCAGCCCGGAGACCAGACATAGCCTGACTGGGTATCAGTGACCCTCTGAGACTA
TGTACTAACCCTTGCCAATCCCCAGGGCACTCTGGTCCCAGTGCCCCGAGACTTGGAACCCTGT
GGAATCCTAGCACGTCGGAAAAAGTCCGAAGCTCTGAAGCCATTTTATAGAGGGTGCAAATGGA
GACTAGAAATTCATCTCTTACCTTCGCTGGCCCCAAGCACTCTTTCTTCCCTTCCCACCCATGC
CCCATGCAAAAATCTAGGGCACCCAGTCATTTCACAGACGGAGTAAATGGATGCTCAGAGTTCA
TCTCTCGTACACTCTGACCCCAGTACCATTTTTCCTGTCCCATTAGGCTCCTACGTACCGTTAG
TCCCCCCCCCATCTCCTAAAAATACTCATACATTGTGTAGTTATTTATAAAATTGTATTTCTCT
TCTTCCACTTACCTCTTATCCCTGCTTTCTAACCTCCTGTCAGCCCGCTCCAGCCCAGACCTTA
AGAGTTTAATTCTGAGGTTCTCTTGGGTTTCTCTACGTTACAAAGGCAGGGGACGTCTCTGCTT
GATTCCCCGTCTTCAGACTGGATGCTGTGGTCCAGGCCCAGGTCTGAAGGAGAGAGCCATTGAA
GGCTCACCATCTCTCTGAGTGGTCTGAATGTGTTTATTCGTTATAAACGAACAGTGATGATCGA

hide sequence

RefSeq Acc Id:

XM_006239080 ⟹ XP_006239142

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	150,473,767 - 150,503,524 (+)	NCBI
mRatBN7.2	5	145,189,815 - 145,216,655 (+)	NCBI
Rnor_6.0	5	151,172,189 - 151,199,746 (+)	NCBI
Rnor_5.0	5	154,839,086 - 154,866,424 (+)	NCBI

Sequence:

show sequence

CCCAGAGTAGGTAGTAGGGACAGGGGCGGGTAGCACTTCACTTTCCCCTCACATCGTTCCTGAA
AATTAGGGTTGGCTCGCCCCAGATCGGGTCACCAGCAGCTGGCTCCCTTGAGACCAGGTTTCCG
GCACCCCCCCCCGCCCCCAGGGACCATGCATCAGTCCTACTGACCCAGGAGTAGGGGCCTGTGG
GCAGGACACCTGGAATGGGCTGTGTGTTCTGCAAGAAGTTAGAGCCTGCACCCAAGGAGGATGT
TGGCCTGGAAGGGGACTTCCGGAGCCAAGGCGCTGAAGAACGCTATTACCCTGACCCTACTCAA
GGCCGGTCTTCGTCCATCTCGCCTCAGCCCATCAGCCCTGCTTTCCTTAATGTTGGCAACATAA
GAAGCGTCTCTGGGACGGGAGTGACCATATTCGTCGCCCTGTATGACTATGAGGCCAGGACAGG
GGATGACCTCACCTTCACCAAAGGCGAGAAGTTCCACATCCTGAACAATACGGAGTATGACTGG
TGGGAGGCTAGGTCCCTGAGCTCCGGACGCACGGGCTATGTTCCCAGCAACTATGTGGCTCCCG
TGGATTCCATCCAGGCTGAAGAGTGGTACTTCGGAAAGATCAGCAGAAAGGATGCAGAGAGGCA
GCTTCTCTCCGATGGCAACCCTCAAGGGGCCTTTCTCATTCGGGAAAGCGAGACCACCAAAGGT
GCCTACTCCCTGTCCATCCGTGACTGGGACCAGAACAGAGGCGACCACATAAAGCATTACAAGA
TCCGAAAGCTGGACATGGGTGGCTACTACATCACCACGCGGGCCCAGTTCGAATCCGTGCAGGA
CCTGGTGCGGCACTACATGGAAGTGAATGACGGTCTATGCTACTTGCTCACGGCACCCTGTATG
GTCATGAAGCCCCAGACTCTAGGCCTGGCTAAGGATGCCTGGGAGATCGACCGTAACTCCATAG
CACTTGACCGCAGGCTGGGCACCGGCTGCTTTGGAGACGTGTGGCTGGGCACGTGGAACTGTAG
CACAAAGGTGGCAGTGAAAACGCTGAAGCCAGGCACCATGTCGCCGAAGGCCTTCCTGGAGGAG
GCACAGATCATGAAACTGCTGAGGCACGACAAGCTGGTGCAGCTGTACGCGGTGGTGTCAGAGG
AACCCATTTATATTGTGACAGAGTTCATGTGCTATGGTAGCTTGCTGGATTTCCTAAAGGATCG
AAAGGGTCACAACTTGATGCTGCCCAATCTAGTGGACATGGCTGCCCAGGTAGCAGAGGGCATG
GCCTACATGGAGCGCATGAACTATATCCACCGAGACCTGAGAGCAGCCAACATCCTGGTGGGGG
AACATCTAATATGCAAGATCGCTGACTTTGGGTTGGCACGCCTCATAGTGGATGATGAGTACAA
CCCCCAACAAGGAACCAAGTTTCCCATCAAGTGGACAGCCCCAGAGGCTGCTCTCTTTGGCAGA
TTCACTGTCAAATCAGACGTGTGGTCCTTTGGGATTCTGCTCACTGAACTGATCACCAAGGGCA
GAGTTCCATACCCAGGTATGAACAACCGGGAAGTGTTGGAACAGGTAGAGCACGGCTACCACAT
GCCATGCCCTCCGGGATGCCCAGTATCCCTGTATGAGGTCATGGAGCAGACCTGGCGTCTGGAT
CCAGAGGAGAGGCCCACCTTTGAGTACCTGCAGTCTTTCCTGGAAGACTATTTCACCTCCACAG
AACCACAGTATCAGCCCGGAGACCAGACATAGCCTGACTGGGTATCAGTGACCCTCTGAGACTA
TGTACTAACCCTTGCCAATCCCCAGGGCACTCTGGTCCCAGTGCCCCGAGACTTGGAACCCTGT
GGAATCCTAGCACGTCGGAAAAAGTCCGAAGCTCTGAAGCCATTTTATAGAGGGTGCAAATGGA
GACTAGAAATTCATCTCTTACCTTCGCTGGCCCCAAGCACTCTTTCTTCCCTTCCCACCCATGC
CCCATGCAAAAATCTAGGGCACCCAGTCATTTCACAGACGGAGTAAATGGATGCTCAGAGTTCA
TCTCTCGTACACTCTGACCCCAGTACCATTTTTCCTGTCCCATTAGGCTCCTACGTACCGTTAG
TCCCCCCCCCATCTCCTAAAAATACTCATACATTGTGTAGTTATTTATAAAATTGTATTTCTCT
TCTTCCACTTACCTCTTATCCCTGCTTTCTAACCTCCTGTCAGCCCGCTCCAGCCCAGACCTTA
AGAGTTTAATTCTGAGGTTCTCTTGGGTTTCTCTACGTTACAAAGGCAGGGGACGTCTCTGCTT
GATTCCCCGTCTTCAGACTGGATGCTGTGGTCCAGGCCCAGGTCTGAAGGAGAGAGCCATTGAA
GGCTCACCATCTCTCTGAGTGGTCTGAATGTGTTTATTCGTTATAAACGAACAGTGATGATCGA

hide sequence

RefSeq Acc Id:

XM_006239081 ⟹ XP_006239143

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	150,473,773 - 150,503,524 (+)	NCBI
mRatBN7.2	5	145,189,819 - 145,216,655 (+)	NCBI
Rnor_6.0	5	151,172,189 - 151,199,746 (+)	NCBI
Rnor_5.0	5	154,839,086 - 154,866,424 (+)	NCBI

Sequence:

show sequence

CCCAGAGTAGGTAGTAGGGACAGGGGCGGGTAGCACTTCACTTTCCCCTCACATCGTTCCTGAA
AATTAGGGTTGGCTCGCCCCAGATCGGGTCACCAGCAGCTGGCTCCCTTGAGACCAGGTAGGCG
GCCAAACCAGGAGGAGGCTGACCCGGCAGGTGTCGCCCCGCCCCTGTCCGTCCTCGCCCTGGAA
GGAAGATTTAGAGGTTTCCGGCACCCCCCCCCGCCCCCAGGGACCATGCATCAGTCCTACTGAC
CCAGGAGTAGGGGCCTGTGGGGACACCTGGAATGGGCTGTGTGTTCTGCAAGAAGTTAGAGCCT
GCACCCAAGGAGGATGTTGGCCTGGAAGGGGACTTCCGGAGCCAAGGCGCTGAAGAACGCTATT
ACCCTGACCCTACTCAAGGCCGGTCTTCGTCCATCTCGCCTCAGCCCATCAGCCCTGCTTTCCT
TAATGTTGGCAACATAAGAAGCGTCTCTGGGACGGGAGTGACCATATTCGTCGCCCTGTATGAC
TATGAGGCCAGGACAGGGGATGACCTCACCTTCACCAAAGGCGAGAAGTTCCACATCCTGAACA
ATACGGAGTATGACTGGTGGGAGGCTAGGTCCCTGAGCTCCGGACGCACGGGCTATGTTCCCAG
CAACTATGTGGCTCCCGTGGATTCCATCCAGGCTGAAGAGTGGTACTTCGGAAAGATCAGCAGA
AAGGATGCAGAGAGGCAGCTTCTCTCCGATGGCAACCCTCAAGGGGCCTTTCTCATTCGGGAAA
GCGAGACCACCAAAGGTGCCTACTCCCTGTCCATCCGTGACTGGGACCAGAACAGAGGCGACCA
CATAAAGCATTACAAGATCCGAAAGCTGGACATGGGTGGCTACTACATCACCACGCGGGCCCAG
TTCGAATCCGTGCAGGACCTGGTGCGGCACTACATGGAAGTGAATGACGGTCTATGCTACTTGC
TCACGGCACCCTGTATGGTCATGAAGCCCCAGACTCTAGGCCTGGCTAAGGATGCCTGGGAGAT
CGACCGTAACTCCATAGCACTTGACCGCAGGCTGGGCACCGGCTGCTTTGGAGACGTGTGGCTG
GGCACGTGGAACTGTAGCACAAAGGTGGCAGTGAAAACGCTGAAGCCAGGCACCATGTCGCCGA
AGGCCTTCCTGGAGGAGGCACAGATCATGAAACTGCTGAGGCACGACAAGCTGGTGCAGCTGTA
CGCGGTGGTGTCAGAGGAACCCATTTATATTGTGACAGAGTTCATGTGCTATGGTAGCTTGCTG
GATTTCCTAAAGGATCGAAAGGGTCACAACTTGATGCTGCCCAATCTAGTGGACATGGCTGCCC
AGGTAGCAGAGGGCATGGCCTACATGGAGCGCATGAACTATATCCACCGAGACCTGAGAGCAGC
CAACATCCTGGTGGGGGAACATCTAATATGCAAGATCGCTGACTTTGGGTTGGCACGCCTCATA
GTGGATGATGAGTACAACCCCCAACAAGGAACCAAGTTTCCCATCAAGTGGACAGCCCCAGAGG
CTGCTCTCTTTGGCAGATTCACTGTCAAATCAGACGTGTGGTCCTTTGGGATTCTGCTCACTGA
ACTGATCACCAAGGGCAGAGTTCCATACCCAGGTATGAACAACCGGGAAGTGTTGGAACAGGTA
GAGCACGGCTACCACATGCCATGCCCTCCGGGATGCCCAGTATCCCTGTATGAGGTCATGGAGC
AGACCTGGCGTCTGGATCCAGAGGAGAGGCCCACCTTTGAGTACCTGCAGTCTTTCCTGGAAGA
CTATTTCACCTCCACAGAACCACAGTATCAGCCCGGAGACCAGACATAGCCTGACTGGGTATCA
GTGACCCTCTGAGACTATGTACTAACCCTTGCCAATCCCCAGGGCACTCTGGTCCCAGTGCCCC
GAGACTTGGAACCCTGTGGAATCCTAGCACGTCGGAAAAAGTCCGAAGCTCTGAAGCCATTTTA
TAGAGGGTGCAAATGGAGACTAGAAATTCATCTCTTACCTTCGCTGGCCCCAAGCACTCTTTCT
TCCCTTCCCACCCATGCCCCATGCAAAAATCTAGGGCACCCAGTCATTTCACAGACGGAGTAAA
TGGATGCTCAGAGTTCATCTCTCGTACACTCTGACCCCAGTACCATTTTTCCTGTCCCATTAGG
CTCCTACGTACCGTTAGTCCCCCCCCCATCTCCTAAAAATACTCATACATTGTGTAGTTATTTA
TAAAATTGTATTTCTCTTCTTCCACTTACCTCTTATCCCTGCTTTCTAACCTCCTGTCAGCCCG
CTCCAGCCCAGACCTTAAGAGTTTAATTCTGAGGTTCTCTTGGGTTTCTCTACGTTACAAAGGC
AGGGGACGTCTCTGCTTGATTCCCCGTCTTCAGACTGGATGCTGTGGTCCAGGCCCAGGTCTGA
AGGAGAGAGCCATTGAAGGCTCACCATCTCTCTGAGTGGTCTGAATGTGTTTATTCGTTATAAA
CGAACAGTGATGATCGA

hide sequence

RefSeq Acc Id:

XM_006239082 ⟹ XP_006239144

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	150,473,773 - 150,503,524 (+)	NCBI
mRatBN7.2	5	145,189,819 - 145,216,655 (+)	NCBI
Rnor_6.0	5	151,172,189 - 151,199,746 (+)	NCBI
Rnor_5.0	5	154,839,086 - 154,866,424 (+)	NCBI

Sequence:

show sequence

CCCAGAGTAGGTAGTAGGGACAGGGGCGGGTAGCACTTCACTTTCCCCTCACATCGTTCCTGAA
AATTAGGGTTGGCTCGCCCCAGATCGGGTCACCAGCAGCTGGCTCCCTTGAGACCAGGTAGGCG
GCCAAACCAGGAGGAGGCTGACCCGGCAGGTGTCGCCCCGCCCCTGTCCGTCCTCGCCCTGGAA
GGAAGATTTAGAGCAGGACACCTGGAATGGGCTGTGTGTTCTGCAAGAAGTTAGAGCCTGCACC
CAAGGAGGATGTTGGCCTGGAAGGGGACTTCCGGAGCCAAGGCGCTGAAGAACGCTATTACCCT
GACCCTACTCAAGGCCGGTCTTCGTCCATCTCGCCTCAGCCCATCAGCCCTGCTTTCCTTAATG
TTGGCAACATAAGAAGCGTCTCTGGGACGGGAGTGACCATATTCGTCGCCCTGTATGACTATGA
GGCCAGGACAGGGGATGACCTCACCTTCACCAAAGGCGAGAAGTTCCACATCCTGAACAATACG
GAGTATGACTGGTGGGAGGCTAGGTCCCTGAGCTCCGGACGCACGGGCTATGTTCCCAGCAACT
ATGTGGCTCCCGTGGATTCCATCCAGGCTGAAGAGTGGTACTTCGGAAAGATCAGCAGAAAGGA
TGCAGAGAGGCAGCTTCTCTCCGATGGCAACCCTCAAGGGGCCTTTCTCATTCGGGAAAGCGAG
ACCACCAAAGGTGCCTACTCCCTGTCCATCCGTGACTGGGACCAGAACAGAGGCGACCACATAA
AGCATTACAAGATCCGAAAGCTGGACATGGGTGGCTACTACATCACCACGCGGGCCCAGTTCGA
ATCCGTGCAGGACCTGGTGCGGCACTACATGGAAGTGAATGACGGTCTATGCTACTTGCTCACG
GCACCCTGTATGGTCATGAAGCCCCAGACTCTAGGCCTGGCTAAGGATGCCTGGGAGATCGACC
GTAACTCCATAGCACTTGACCGCAGGCTGGGCACCGGCTGCTTTGGAGACGTGTGGCTGGGCAC
GTGGAACTGTAGCACAAAGGTGGCAGTGAAAACGCTGAAGCCAGGCACCATGTCGCCGAAGGCC
TTCCTGGAGGAGGCACAGATCATGAAACTGCTGAGGCACGACAAGCTGGTGCAGCTGTACGCGG
TGGTGTCAGAGGAACCCATTTATATTGTGACAGAGTTCATGTGCTATGGTAGCTTGCTGGATTT
CCTAAAGGATCGAAAGGGTCACAACTTGATGCTGCCCAATCTAGTGGACATGGCTGCCCAGGTA
GCAGAGGGCATGGCCTACATGGAGCGCATGAACTATATCCACCGAGACCTGAGAGCAGCCAACA
TCCTGGTGGGGGAACATCTAATATGCAAGATCGCTGACTTTGGGTTGGCACGCCTCATAGTGGA
TGATGAGTACAACCCCCAACAAGGAACCAAGTTTCCCATCAAGTGGACAGCCCCAGAGGCTGCT
CTCTTTGGCAGATTCACTGTCAAATCAGACGTGTGGTCCTTTGGGATTCTGCTCACTGAACTGA
TCACCAAGGGCAGAGTTCCATACCCAGGTATGAACAACCGGGAAGTGTTGGAACAGGTAGAGCA
CGGCTACCACATGCCATGCCCTCCGGGATGCCCAGTATCCCTGTATGAGGTCATGGAGCAGACC
TGGCGTCTGGATCCAGAGGAGAGGCCCACCTTTGAGTACCTGCAGTCTTTCCTGGAAGACTATT
TCACCTCCACAGAACCACAGTATCAGCCCGGAGACCAGACATAGCCTGACTGGGTATCAGTGAC
CCTCTGAGACTATGTACTAACCCTTGCCAATCCCCAGGGCACTCTGGTCCCAGTGCCCCGAGAC
TTGGAACCCTGTGGAATCCTAGCACGTCGGAAAAAGTCCGAAGCTCTGAAGCCATTTTATAGAG
GGTGCAAATGGAGACTAGAAATTCATCTCTTACCTTCGCTGGCCCCAAGCACTCTTTCTTCCCT
TCCCACCCATGCCCCATGCAAAAATCTAGGGCACCCAGTCATTTCACAGACGGAGTAAATGGAT
GCTCAGAGTTCATCTCTCGTACACTCTGACCCCAGTACCATTTTTCCTGTCCCATTAGGCTCCT
ACGTACCGTTAGTCCCCCCCCCATCTCCTAAAAATACTCATACATTGTGTAGTTATTTATAAAA
TTGTATTTCTCTTCTTCCACTTACCTCTTATCCCTGCTTTCTAACCTCCTGTCAGCCCGCTCCA
GCCCAGACCTTAAGAGTTTAATTCTGAGGTTCTCTTGGGTTTCTCTACGTTACAAAGGCAGGGG
ACGTCTCTGCTTGATTCCCCGTCTTCAGACTGGATGCTGTGGTCCAGGCCCAGGTCTGAAGGAG
AGAGCCATTGAAGGCTCACCATCTCTCTGAGTGGTCTGAATGTGTTTATTCGTTATAAACGAAC
AGTGATGATCGA

hide sequence

RefSeq Acc Id:

XM_039110824 ⟹ XP_038966752

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	150,483,521 - 150,503,524 (+)	NCBI
mRatBN7.2	5	145,199,567 - 145,219,571 (+)	NCBI

RefSeq Acc Id:

XM_039110825 ⟹ XP_038966753

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	150,481,353 - 150,503,524 (+)	NCBI
mRatBN7.2	5	145,197,402 - 145,217,076 (+)	NCBI

RefSeq Acc Id:

XM_039110826 ⟹ XP_038966754

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	150,473,767 - 150,503,524 (+)	NCBI
mRatBN7.2	5	145,189,814 - 145,216,655 (+)	NCBI

RefSeq Acc Id:

XM_039110827 ⟹ XP_038966755

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	150,483,526 - 150,503,524 (+)	NCBI
mRatBN7.2	5	145,199,571 - 145,216,655 (+)	NCBI

RefSeq Acc Id:

XM_039110829 ⟹ XP_038966757

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	150,473,797 - 150,503,524 (+)	NCBI
mRatBN7.2	5	145,189,848 - 145,216,655 (+)	NCBI

RefSeq Acc Id:

XM_063288461 ⟹ XP_063144531

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	150,483,705 - 150,503,524 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_077059	(Get FASTA)	NCBI Sequence Viewer
	XP_006239141	(Get FASTA)	NCBI Sequence Viewer
	XP_006239142	(Get FASTA)	NCBI Sequence Viewer
	XP_006239143	(Get FASTA)	NCBI Sequence Viewer
	XP_006239144	(Get FASTA)	NCBI Sequence Viewer
	XP_038966752	(Get FASTA)	NCBI Sequence Viewer
	XP_038966753	(Get FASTA)	NCBI Sequence Viewer
	XP_038966754	(Get FASTA)	NCBI Sequence Viewer
	XP_038966755	(Get FASTA)	NCBI Sequence Viewer
	XP_038966757	(Get FASTA)	NCBI Sequence Viewer
	XP_063144531	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH62025	(Get FASTA)	NCBI Sequence Viewer
	CAA40337	(Get FASTA)	NCBI Sequence Viewer
	EDL80655	(Get FASTA)	NCBI Sequence Viewer
	EDL80656	(Get FASTA)	NCBI Sequence Viewer
	EDL80657	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000013779
	ENSRNOP00000013779.3
	ENSRNOP00055033841
	ENSRNOP00060039519
	ENSRNOP00065040893
GenBank Protein	Q6P6U0	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_077059 ⟸ NM_024145

- UniProtKB:

Q63206 (UniProtKB/Swiss-Prot), Q6P6U0 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MGCVFCKKLEPAPKEDVGLEGDFRSQGAEERYYPDPTQGRSSSISPQPISPAFLNVGNIRSVSG
TGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDWWEARSLSSGRTGYVPSNYVAPVDSIQ
AEEWYFGKISRKDAERQLLSDGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHYKIRKLD
MGGYYITTRAQFESVQDLVRHYMEVNDGLCYLLTAPCMVMKPQTLGLAKDAWEIDRNSIALDRR
LGTGCFGDVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYI
VTEFMCYGSLLDFLKDRKGHNLMLPNLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEHLIC
KIADFGLARLIVDDEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYP
GMNNREVLEQVEHGYHMPCPPGCPVSLYEVMEQTWRLDPEERPTFEYLQSFLEDYFTSTEPQYQ
PGDQT

hide sequence

RefSeq Acc Id:	XP_006239143 ⟸ XM_006239081
- Peptide Label:	isoform X1
- UniProtKB:	Q63206 (UniProtKB/Swiss-Prot), Q6P6U0 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MGCVFCKKLEPAPKEDVGLEGDFRSQGAEERYYPDPTQGRSSSISPQPISPAFLNVGNIRSVSG TGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDWWEARSLSSGRTGYVPSNYVAPVDSIQ AEEWYFGKISRKDAERQLLSDGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHYKIRKLD MGGYYITTRAQFESVQDLVRHYMEVNDGLCYLLTAPCMVMKPQTLGLAKDAWEIDRNSIALDRR LGTGCFGDVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYI VTEFMCYGSLLDFLKDRKGHNLMLPNLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEHLIC KIADFGLARLIVDDEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYP GMNNREVLEQVEHGYHMPCPPGCPVSLYEVMEQTWRLDPEERPTFEYLQSFLEDYFTSTEPQYQ PGDQT hide sequence

RefSeq Acc Id:	XP_006239144 ⟸ XM_006239082
- Peptide Label:	isoform X1
- UniProtKB:	Q63206 (UniProtKB/Swiss-Prot), Q6P6U0 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MGCVFCKKLEPAPKEDVGLEGDFRSQGAEERYYPDPTQGRSSSISPQPISPAFLNVGNIRSVSG TGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDWWEARSLSSGRTGYVPSNYVAPVDSIQ AEEWYFGKISRKDAERQLLSDGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHYKIRKLD MGGYYITTRAQFESVQDLVRHYMEVNDGLCYLLTAPCMVMKPQTLGLAKDAWEIDRNSIALDRR LGTGCFGDVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYI VTEFMCYGSLLDFLKDRKGHNLMLPNLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEHLIC KIADFGLARLIVDDEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYP GMNNREVLEQVEHGYHMPCPPGCPVSLYEVMEQTWRLDPEERPTFEYLQSFLEDYFTSTEPQYQ PGDQT hide sequence

RefSeq Acc Id:	XP_006239142 ⟸ XM_006239080
- Peptide Label:	isoform X1
- UniProtKB:	Q63206 (UniProtKB/Swiss-Prot), Q6P6U0 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MGCVFCKKLEPAPKEDVGLEGDFRSQGAEERYYPDPTQGRSSSISPQPISPAFLNVGNIRSVSG TGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDWWEARSLSSGRTGYVPSNYVAPVDSIQ AEEWYFGKISRKDAERQLLSDGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHYKIRKLD MGGYYITTRAQFESVQDLVRHYMEVNDGLCYLLTAPCMVMKPQTLGLAKDAWEIDRNSIALDRR LGTGCFGDVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYI VTEFMCYGSLLDFLKDRKGHNLMLPNLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEHLIC KIADFGLARLIVDDEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYP GMNNREVLEQVEHGYHMPCPPGCPVSLYEVMEQTWRLDPEERPTFEYLQSFLEDYFTSTEPQYQ PGDQT hide sequence

RefSeq Acc Id:	XP_006239141 ⟸ XM_006239079
- Peptide Label:	isoform X1
- UniProtKB:	Q63206 (UniProtKB/Swiss-Prot), Q6P6U0 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MGCVFCKKLEPAPKEDVGLEGDFRSQGAEERYYPDPTQGRSSSISPQPISPAFLNVGNIRSVSG TGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDWWEARSLSSGRTGYVPSNYVAPVDSIQ AEEWYFGKISRKDAERQLLSDGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHYKIRKLD MGGYYITTRAQFESVQDLVRHYMEVNDGLCYLLTAPCMVMKPQTLGLAKDAWEIDRNSIALDRR LGTGCFGDVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYI VTEFMCYGSLLDFLKDRKGHNLMLPNLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEHLIC KIADFGLARLIVDDEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYP GMNNREVLEQVEHGYHMPCPPGCPVSLYEVMEQTWRLDPEERPTFEYLQSFLEDYFTSTEPQYQ PGDQT hide sequence

RefSeq Acc Id:

ENSRNOP00000075272 ⟸ ENSRNOT00000085674

RefSeq Acc Id:

ENSRNOP00000013779 ⟸ ENSRNOT00000013778

RefSeq Acc Id:	XP_038966754 ⟸ XM_039110826
- Peptide Label:	isoform X1
- UniProtKB:	Q6P6U0 (UniProtKB/Swiss-Prot), Q63206 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038966757 ⟸ XM_039110829
- Peptide Label:	isoform X1
- UniProtKB:	Q6P6U0 (UniProtKB/Swiss-Prot), Q63206 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038966753 ⟸ XM_039110825
- Peptide Label:	isoform X1
- UniProtKB:	Q6P6U0 (UniProtKB/Swiss-Prot), Q63206 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038966752 ⟸ XM_039110824
- Peptide Label:	isoform X1
- UniProtKB:	Q6P6U0 (UniProtKB/Swiss-Prot), Q63206 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038966755 ⟸ XM_039110827
- Peptide Label:	isoform X1
- UniProtKB:	Q6P6U0 (UniProtKB/Swiss-Prot), Q63206 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_063144531 ⟸ XM_063288461
- Peptide Label:	isoform X1
- UniProtKB:	Q6P6U0 (UniProtKB/Swiss-Prot), Q63206 (UniProtKB/Swiss-Prot)

Protein Domains

Protein kinase SH2 SH3

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6P6U0-F1-model_v2	AlphaFold	Q6P6U0	1-517	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694108

Promoter ID:

EPDNEW_R4631

Type:

single initiation site

Name:

Fgr_1

Description:

FGR proto-oncogene, Src family tyrosine kinase

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	151,172,228 - 151,172,288	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621319	AgrOrtholog
BioCyc Gene	G2FUF-39648	BioCyc
Ensembl Genes	ENSRNOG00000009912	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOG00055024231	UniProtKB/Swiss-Prot
	ENSRNOG00060027348	UniProtKB/Swiss-Prot
	ENSRNOG00065028857	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000013778	ENTREZGENE
	ENSRNOT00000013778.6	UniProtKB/Swiss-Prot
	ENSRNOT00055041597	UniProtKB/Swiss-Prot
	ENSRNOT00060047477	UniProtKB/Swiss-Prot
	ENSRNOT00065049807	UniProtKB/Swiss-Prot
Gene3D-CATH	3.30.505.10	UniProtKB/Swiss-Prot
	SH3 Domains	UniProtKB/Swiss-Prot
	Transferase(Phosphotransferase) domain 1	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:5623501	IMAGE-MGC_LOAD
InterPro	Fgr_SH2	UniProtKB/Swiss-Prot
	Kinase-like_dom_sf	UniProtKB/Swiss-Prot
	Prot_kinase_dom	UniProtKB/Swiss-Prot
	Protein_kinase_ATP_BS	UniProtKB/Swiss-Prot
	Ser-Thr/Tyr_kinase_cat_dom	UniProtKB/Swiss-Prot
	SH2	UniProtKB/Swiss-Prot
	SH2_dom_sf	UniProtKB/Swiss-Prot
	SH3-like_dom_sf	UniProtKB/Swiss-Prot
	SH3_domain	UniProtKB/Swiss-Prot
	Tyr_kinase_AS	UniProtKB/Swiss-Prot
	Tyr_kinase_cat_dom	UniProtKB/Swiss-Prot
KEGG Report	rno:79113	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:72428	IMAGE-MGC_LOAD
NCBI Gene	79113	ENTREZGENE
PANTHER	TYROSINE-PROTEIN KINASE	UniProtKB/Swiss-Prot
	TYROSINE-PROTEIN KINASE FGR	UniProtKB/Swiss-Prot
Pfam	Pkinase_Tyr	UniProtKB/Swiss-Prot
	SH2	UniProtKB/Swiss-Prot
	SH3_1	UniProtKB/Swiss-Prot
PhenoGen	Fgr	PhenoGen
PRINTS	SH2DOMAIN	UniProtKB/Swiss-Prot
	SH3DOMAIN	UniProtKB/Swiss-Prot
	TYRKINASE	UniProtKB/Swiss-Prot
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/Swiss-Prot
	PROTEIN_KINASE_DOM	UniProtKB/Swiss-Prot
	PROTEIN_KINASE_TYR	UniProtKB/Swiss-Prot
	SH2	UniProtKB/Swiss-Prot
	SH3	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000009912	RatGTEx
	ENSRNOG00055024231	RatGTEx
	ENSRNOG00060027348	RatGTEx
	ENSRNOG00065028857	RatGTEx
SMART	SH2	UniProtKB/Swiss-Prot
	SH3	UniProtKB/Swiss-Prot
	TyrKc	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF50044	UniProtKB/Swiss-Prot
	SSF55550	UniProtKB/Swiss-Prot
	SSF56112	UniProtKB/Swiss-Prot
UniProt	FGR_RAT	UniProtKB/Swiss-Prot
	Q63206	ENTREZGENE
	Q6P6U0	ENTREZGENE
UniProt Secondary	Q63206	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2014-07-23	Fgr	FGR proto-oncogene, Src family tyrosine kinase	Fgr	feline Gardner-Rasheed sarcoma viral oncogene	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-07-18	Fgr	feline Gardner-Rasheed sarcoma viral oncogene	Fgr	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-10-29	Fgr	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog		FGR	Name updated	1299863	APPROVED
2002-08-07	Fgr	FGR			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)