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Gene-Chemical Interaction AnnotationsGene-Chemical Interaction Annotations
Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-catechin | decreases expression | ISO | RGD:732668 | 6480464 | Catechin results in decreased expression of LYN mRNA | CTD | PMID:15465739 | 17alpha-ethynylestradiol | increases expression | ISO | RGD:732669 | 6480464 | Ethinyl Estradiol results in increased expression of LYN mRNA | CTD | PMID:17555576 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of LYN mRNA | CTD | PMID:15834898 PMID:17557909 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of LYN mRNA | CTD | PMID:17557909 PMID:15834898 | 17beta-estradiol | multiple interactions | ISO | RGD:732668 | 6480464 | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of LYN mRNA | CTD | PMID:19619570 | 17beta-estradiol | multiple interactions | ISO | RGD:732668 | 6480464 | [Raloxifene co-treated with Estradiol] results in increased expression of LYN mRNA | CTD | PMID:21185374 | 17beta-estradiol | decreases expression | ISO | RGD:732668 | 6480464 | Estradiol results in decreased expression of LYN mRNA | CTD | PMID:19619570 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:732668 | 6480464 | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of LYN mRNA | CTD | PMID:19619570 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:732668 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LYN mRNA | CTD | PMID:20106945 PMID:21632981 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LYN mRNA | CTD | PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of LYN mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:732669 | 6480464 | Tetrachlorodibenzodioxin affects the expression of LYN mRNA | CTD | PMID:20702594 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:732668 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LYN mRNA | CTD | PMID:20106945 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:732668 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of LYN mRNA | CTD | PMID:19619570 | 2-ethoxyethanol | increases expression | EXP | | 6480464 | 2-ethoxyethanol results in increased expression of LYN mRNA | CTD | PMID:19643169 | 2-methoxyethanol | increases expression | EXP | | 6480464 | methyl cellosolve results in increased expression of LYN mRNA | CTD | PMID:19643169 | 3,3',4,4',5-pentachlorobiphenyl | affects expression | ISO | RGD:732669 | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl affects the expression of LYN mRNA | CTD | PMID:20702594 | 4-hydroxynon-2-enal | decreases expression | ISO | RGD:732669 | 6480464 | 4-hydroxy-2-nonenal results in decreased expression of LYN mRNA | CTD | PMID:19191707 | 4-hydroxynon-2-enal | decreases expression | ISO | RGD:732668 | 6480464 | 4-hydroxy-2-nonenal results in decreased expression of LYN mRNA | CTD | PMID:12419474 | acetylsalicylic acid | increases expression | ISO | RGD:732668 | 6480464 | Aspirin results in increased expression of LYN mRNA | CTD | PMID:15928584 | afimoxifene | decreases response to substance | ISO | RGD:732668 | 6480464 | LYN results in decreased susceptibility to 4-hydroxytamoxifen | CTD | PMID:21233418 | all-trans-retinoic acid | increases expression | ISO | RGD:732668 | 6480464 | Tretinoin results in increased expression of LYN mRNA | CTD | PMID:12875902 | all-trans-retinoic acid | increases expression | ISO | RGD:732668 | 6480464 | Tretinoin results in increased expression of LYN mRNA | CTD | PMID:15498508 PMID:12875902 | all-trans-retinoic acid | increases expression | ISO | RGD:732668 | 6480464 | Tretinoin results in increased expression of LYN mRNA | CTD | PMID:12875902 PMID:15498508 | all-trans-retinoic acid | decreases expression | ISO | RGD:732668 | 6480464 | Tretinoin results in decreased expression of LYN mRNA | CTD | PMID:21934132 | aluminium trifluoride | increases phosphorylation | ISO | RGD:732669 | 6480464 | aluminum fluoride results in increased phosphorylation of LYN protein | CTD | PMID:8559152 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of LYN mRNA | CTD | PMID:16483693 | benzo[a]pyrene | multiple interactions | ISO | RGD:732669 | 6480464 | [Benzo(a)pyrene co-treated with XPA gene mutant form co-treated with TRP53 gene mutant form] results in decreased expression of LYN mRNA | CTD | PMID:21715664 | benzo[a]pyrene | decreases expression | ISO | RGD:732669 | 6480464 | Benzo(a)pyrene results in decreased expression of LYN mRNA | CTD | PMID:21569818 | calcitriol | increases expression | ISO | RGD:732668 | 6480464 | Calcitriol results in increased expression of LYN mRNA | CTD | PMID:12875902 | cisplatin | decreases expression | ISO | RGD:732668 | 6480464 | Cisplatin results in decreased expression of LYN mRNA | CTD | PMID:21603599 | copper(2+) sulfate | increases expression | ISO | RGD:732668 | 6480464 | Copper Sulfate results in increased expression of LYN mRNA | CTD | PMID:19549813 | coumestrol | decreases expression | ISO | RGD:732668 | 6480464 | Coumestrol results in decreased expression of LYN mRNA | CTD | PMID:19167446 | cytarabine | decreases expression | ISO | RGD:732668 | 6480464 | Cytarabine results in decreased expression of LYN mRNA | CTD | PMID:21198554 | dasatinib (anhydrous) | decreases activity | ISO | RGD:732668 | 6480464 | dasatinib results in decreased activity of LYN protein | CTD | PMID:18550857 | dasatinib (anhydrous) | multiple interactions | ISO | RGD:732668 | 6480464 | dasatinib results in decreased phosphorylation of and results in decreased activity of LYN protein | CTD | PMID:17020995 | dasatinib (anhydrous) | multiple interactions | ISO | RGD:732668 | 6480464 | dasatinib binds to and results in decreased phosphorylation of LYN protein | CTD | PMID:18180381 | dexamethasone | affects expression | ISO | RGD:732668 | 6480464 | Dexamethasone affects the expression of LYN mRNA | CTD | PMID:12732289 | dichlorine | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in increased expression of LYN mRNA | CTD | PMID:18636392 | dichlorine | increases expression | EXP | | 6480464 | Chlorine results in increased expression of LYN mRNA | CTD | PMID:18636392 | diethylstilbestrol | increases expression | ISO | RGD:732668 | 6480464 | Diethylstilbestrol results in increased expression of LYN mRNA | CTD | PMID:15766595 | ethanol | decreases expression | EXP | | 6480464 | Ethanol results in decreased expression of LYN mRNA | CTD | PMID:15353170 | ethanol | multiple interactions | EXP | | 6480464 | Ethanol results in increased expression of [ITGA2 protein binds to LYN protein binds to TRPV4 protein] | CTD | PMID:18234883 | imatinib | decreases response to substance | ISO | RGD:732668 | 6480464 | LYN results in decreased susceptibility to imatinib | CTD | PMID:17595328 | imatinib | decreases response to substance | ISO | RGD:732668 | 6480464 | LYN protein results in decreased susceptibility to imatinib | CTD | PMID:17432977 | imatinib | multiple interactions | ISO | RGD:732668 | 6480464 | [Mycophenolic Acid co-treated with imatinib] results in decreased phosphorylation of LYN protein | CTD | PMID:15604220 | indomethacin | decreases expression | ISO | RGD:732668 | 6480464 | Indomethacin results in decreased expression of LYN mRNA | CTD | PMID:16984733 | isotretinoin | increases expression | ISO | RGD:732668 | 6480464 | Isotretinoin results in increased expression of LYN mRNA | CTD | PMID:20436886 | mycophenolic acid | multiple interactions | ISO | RGD:732668 | 6480464 | [Mycophenolic Acid co-treated with imatinib] results in decreased phosphorylation of LYN protein | CTD | PMID:15604220 | ozone | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in increased expression of LYN mRNA | CTD | PMID:18636392 | ozone | decreases expression | EXP | | 6480464 | Ozone results in decreased expression of LYN mRNA | CTD | PMID:16330353 | phenobarbital | decreases expression | EXP | | 6480464 | Phenobarbital results in decreased expression of LYN mRNA | CTD | PMID:12807726 | phosgene | affects expression | ISO | RGD:732669 | 6480464 | Phosgene affects the expression of LYN mRNA | CTD | PMID:16300373 | pirinixic acid | decreases expression | ISO | RGD:732669 | 6480464 | pirinixic acid results in decreased expression of LYN mRNA | CTD | PMID:18445702 | quercetin | increases expression | ISO | RGD:732668 | 6480464 | Quercetin results in increased expression of LYN mRNA | CTD | PMID:21632981 | raloxifene | multiple interactions | ISO | RGD:732668 | 6480464 | [Raloxifene co-treated with Estradiol] results in increased expression of LYN mRNA | CTD | PMID:21185374 | tamibarotene | increases expression | ISO | RGD:732668 | 6480464 | Am 80 results in increased expression of LYN mRNA; more ... | CTD | PMID:15498508 | tamoxifen | affects expression | ISO | RGD:732669 | 6480464 | Tamoxifen affects the expression of LYN mRNA | CTD | PMID:17555576 | taurine | decreases expression | ISO | RGD:732668 | 6480464 | Taurine results in decreased expression of LYN mRNA | CTD | PMID:16579726 | tert-butyl hydroperoxide | decreases expression | ISO | RGD:732668 | 6480464 | tert-Butylhydroperoxide results in decreased expression of LYN mRNA | CTD | PMID:12419474 | vancomycin | decreases expression | ISO | RGD:732669 | 6480464 | Vancomycin results in decreased expression of LYN mRNA | CTD | PMID:18930951 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology AnnotationsMolecular Pathway AnnotationsDisease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Molecular Pathway Annotations
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| External Database Links | |
| KEGG Pathway | B cell receptor signaling pathway |
| Chemokine signaling pathway | |
| Epstein-Barr virus infection | |
| Fc epsilon RI signaling pathway | |
| Fc gamma R-mediated phagocytosis | |
| Long-term depression | |
| NF-kappa B signaling pathway | |
| Viral carcinogenesis | |
| Pathway Interaction Database | Alpha-synuclein signaling (PID:200219) |
| amb2 Integrin signaling (PID:200127) | |
| BCR signaling pathway (PID:200006) | |
| Class I PI3K signaling events (PID:200116) | |
| CXCR4-mediated signaling events (PID:200099) | |
| EPHA forward signaling (PID:200142) | |
| Ephrin B reverse signaling (PID:200204) | |
| EPO signaling pathway (PID:200183) | |
| Fc-epsilon receptor I signaling in mast cells (PID:200004) | |
| Glypican 1 network (PID:200026) | |
| GMCSF-mediated signaling events (PID:200019) | |
| IL5-mediated signaling events (PID:200107) | |
| IL8- and CXCR1-mediated signaling events (PID:200199) | |
| IL8- and CXCR2-mediated signaling events (PID:200167) | |
| LPA receptor mediated events (PID:200013) | |
| PDGFR-beta signaling pathway (PID:200149) | |
| Regulation of p38-alpha and p38-beta (PID:200066) | |
| Signaling events mediated by PTP1B (PID:200042) | |
| Signaling events mediated by Stem cell factor receptor (c-Kit) (PID:200181) | |
| Thromboxane A2 receptor signaling (PID:200082) | |
References - curated| 1. |
Alessandri-Haber N, etal., J Neurosci. 2008 Jan 30;28(5):1046-57. |
| 2. |
Amir-Moazami O, etal., J Biol Chem. 2008 Sep 12;283(37):25514-23. Epub 2008 Jun 25. |
| 3. |
Anderwald C, etal., Mol Endocrinol 2002 Jul;16(7):1612-28. |
| 4. |
Colognato H, etal., J Cell Biol. 2004 Oct 25;167(2):365-75. |
| 5. |
Das R, etal., Biophys J. 2008 Jun;94(12):4996-5008. Epub 2008 Mar 7. |
| 6. |
Draberova L, etal., Int Immunol. 1999 Nov;11(11):1829-39. |
| 7. |
Fazal N, etal., Am J Physiol Cell Physiol. 2002 Nov;283(5):C1469-79. |
| 8. |
Fujii Y, etal., FEBS Lett 2003 Apr 10;540(1-3):111-6. |
| 9. |
GOA data from the GO Consortium |
| 10. |
He H, etal., Cardiovasc Drugs Ther. 2006 Aug;20(4):259-71. |
| 11. |
Honda Z, etal., J Biol Chem. 1997 Oct 10;272(41):25753-60. |
| 12. |
Kalia LV and Salter MW, Neuropharmacology. 2003 Nov;45(6):720-8. |
| 13. |
Kamei T, etal., Mol Endocrinol 2002 Jul;16(7):1469-81. |
| 14. |
Kasahara K, etal., J Biol Chem. 2000 Nov 3;275(44):34701-9. |
| 15. |
Kato N, etal., J Immunol. 2006 Jul 1;177(1):147-54. |
| 16. |
Kimura T, etal., J Biol Chem. 1996 Nov 1;271(44):27962-8. |
| 17. |
Konno R, etal., Am J Reprod Immunol. 2007 Oct;58(4):330-43. |
| 18. |
Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7 |
| 19. |
Kyo S, etal., Genes Cells. 2003 Oct;8(10):825-36. |
| 20. |
Lara M, etal., J Immunol. 2001 Oct 15;167(8):4329-37. |
| 21. |
Leung WH and Bolland S, J Immunol. 2007 Jul 1;179(1):95-102. |
| 22. |
Maeno K, etal., J Biol Chem. 2003 Jul 4;278(27):24912-20. Epub 2003 Apr 22. |
| 23. |
Mallozzi C, etal., J Neurosci Res. 2007 Sep;85(12):2770-7. |
| 24. |
MGD data from the GO Consortium |
| 25. |
Minoguchi K, etal., J Biol Chem. 1994 Feb 18;269(7):5249-54. |
| 26. |
Minoguchi K, etal., Mol Immunol. 1994 May;31(7):519-29. |
| 27. |
Muller G, etal., Biochem Pharmacol. 2005 Mar 1;69(5):761-80. Epub 2005 Jan 25. |
| 28. |
Napolitano M, etal., Neurosci Lett. 2006 May 8;398(3):211-4. Epub 2006 Mar 9. |
| 29. |
Narisawa-Saito M, etal., Clin Exp Immunol. 1996 Oct;106(1):86-90. |
| 30. |
NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 31. |
Pace A, etal., Biochim Biophys Acta. 2006 Apr;1763(4):356-65. Epub 2006 Apr 7. |
| 32. |
Pipeline to import KEGG annotations from KEGG into RGD Pathway Ontology |
| 33. |
Pipeline to import Pathway Interaction Database annotations from NCI into RGD |
| 34. |
Pullar CE, etal., J Immunol. 1996 Aug 1;157(3):1226-32. |
| 35. |
RGD automated import pipeline for gene-chemical interactions |
| 36. |
Rider LG, etal., Gene 1994 Jan 28;138(1-2):219-22. |
| 37. |
Salvi M, etal., Biochim Biophys Acta 2002 Apr 3;1589(2):181-95. |
| 38. |
Sheets ED, etal., J Cell Biol. 1999 May 17;145(4):877-87. |
| 39. |
Song JS, etal., Oncogene. 1998 Jul 2;16(26):3357-68. |
| 40. |
Stenberg PE, etal., Blood. 1997 Apr 1;89(7):2384-93. |
| 41. |
Tsuda M, etal., Glia. 2008 Jan 1;56(1):50-8. |
| 42. |
Tsukita S, etal., J Cell Biol. 1991 May;113(4):867-79. |
| 43. |
Vonakis BM, etal., J Biol Chem 1997 Sep 19;272(38):24072-80. |
| 44. |
Vonakis BM, etal., J Immunol. 2005 Oct 1;175(7):4543-54. |
| 45. |
Wu X, etal., J Neurochem. 2004 Aug;90(4):807-18. |
| 46. |
Xie ZH, etal., J Immunol. 2002 May 1;168(9):4682-91. |
| 47. |
Xu R, etal., J Immunol 2001 Dec 1;167(11):6394-402. |
References - uncurated| PubMed | 11137137 |
| 11744621 | |
| 12670955 | |
| 14604964 | |
| 14769131 | |
| 16791881 | |
| 17977829 | |
| 18250449 | |
| 18682390 | |
| 19832701 | |
| 8627181 | |
| 8761480 |
RGD Disease Portals| Lyn has been annotated in the following RGD Disease Portals. |
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Candidate Gene StatusComparative Map Data| Lyn (Rattus norvegicus) |
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| LYN (Homo sapiens) |
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| Lyn (Mus musculus) |
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Position Markers| D5Rat206 |
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| D0Got982 |
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| RH140554 |
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| RH94837 |
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| RH94838 |
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QTLs in Region (RGSC Genome Assembly v3.4)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
Nucleotide Sequences| Nucleotide RefSeqs | NM_001111098 | (Get FASTA) | Search GEO for Microarray Profiles |
| NM_030857 | (Get FASTA) | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR06035154 | (Get FASTA) | Search GEO for Microarray Profiles |
| AABR06035155 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06035156 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06035157 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06035158 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06035159 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06035160 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06035161 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01034587 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01034588 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01034589 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01034590 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AF000300 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AF000301 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AF000302 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CH473984 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L14782 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L14823 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L14951 | (Get FASTA) | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | NM_030857 | ||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Protein Acc Id: | NP_110484 | ||||||||||||||||||||
| Peptide Label: | isoform A | ||||||||||||||||||||
| Position: |
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| RefSeq Acc Id: | NM_001111098 | ||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Protein Acc Id: | NP_001104568 | ||||||||||||||||||||
| Peptide Label: | isoform B | ||||||||||||||||||||
| Position: |
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Protein Sequences| Protein RefSeqs | NP_001104568 | (Get FASTA) |
| NP_110484 | (Get FASTA) | |
| GenBank Protein | AAA20944 | (Get FASTA) |
| AAA20945 | (Get FASTA) | |
| AAA41549 | (Get FASTA) | |
| AAB71344 | (Get FASTA) | |
| AAB71345 | (Get FASTA) | |
| AAB71346 | (Get FASTA) | |
| EDM11604 | (Get FASTA) | |
| EDM11605 | (Get FASTA) | |
| EDM11606 | (Get FASTA) | |
| EDM11607 | (Get FASTA) | |
| Q07014 | (Get FASTA) |
Strain Sequence Variants
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External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSRNOG00000008180 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Protein | ENSRNOP00000011130 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Transcript | ENSRNOT00000011130 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Entrez Gene | 81515 | ENTREZGENE |
| Gene3D-CATH | SH2 | UniProtKB/Swiss-Prot |
| Germonline | ENSRNOG00000008180 | UniProtKB/Swiss-Prot |
| HomoloGene Group ID | 55649 | ENTREZGENE |
| InterPro | Kinase-like_dom | UniProtKB/Swiss-Prot |
| Prot_kinase_cat_dom | UniProtKB/Swiss-Prot | |
| Protein_kinase_ATP_BS | UniProtKB/Swiss-Prot | |
| Ser-Thr/Tyr-Pkinase | UniProtKB/Swiss-Prot | |
| SH2 | UniProtKB/Swiss-Prot | |
| SH3_domain | UniProtKB/Swiss-Prot | |
| Tyr_Pkinase_cat_dom | UniProtKB/Swiss-Prot | |
| Tyr_prot_kinase_AS | UniProtKB/Swiss-Prot | |
| IPI | IPI00195871 | UniProtKB/Swiss-Prot |
| IPI00327644 | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:81515 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Pfam | Pkinase_Tyr | UniProtKB/Swiss-Prot |
| SH2 | UniProtKB/Swiss-Prot | |
| SH3_1 | UniProtKB/Swiss-Prot | |
| PRINTS | SH2DOMAIN | UniProtKB/Swiss-Prot |
| SH3DOMAIN | UniProtKB/Swiss-Prot | |
| TYRKINASE | UniProtKB/Swiss-Prot | |
| PROSITE | PROTEIN_KINASE_ATP | UniProtKB/Swiss-Prot |
| PROTEIN_KINASE_DOM | UniProtKB/Swiss-Prot | |
| PROTEIN_KINASE_TYR | UniProtKB/Swiss-Prot | |
| SH2 | UniProtKB/Swiss-Prot | |
| SH3 | UniProtKB/Swiss-Prot | |
| SMART | SH2 | UniProtKB/Swiss-Prot |
| SH3 | UniProtKB/Swiss-Prot | |
| TyrKc | UniProtKB/Swiss-Prot | |
| Superfamily-SCOP | Kinase_like | UniProtKB/Swiss-Prot |
| SH3 | UniProtKB/Swiss-Prot | |
| UniGene | Rn.4338 | ENTREZGENE |
| UniProt | LYN_RAT | UniProtKB/Swiss-Prot |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2008-09-18 | Lyn | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | Lyn | Yamaguchi sarcoma viral (v-yes-1) oncogene homolog | Nomenclature updated to reflect human and mouse nomenclature | 10779 | APPROVED |
| 2005-01-20 | Lyn | Yamaguchi sarcoma viral (v-yes-1) oncogene homolog | lyn protein non-receptor kinase | Name updated | 10779 | APPROVED | |
| 2002-08-07 | Lyn | lyn protein non-receptor kinase | Symbol and Name status set to provisional | 1724 | PROVISIONAL |
RGD Curation Notes| Note Type | Note | Reference |
|---|---|---|
| gene_physical_interaction | interacts with PI3-K | 632179 |
| gene_process | mediates PI3-K/Akt signaling pathway | 632179 |
| gene_process | mediates PI3-K/Akt signaling pathway | 632179 |
| More on Lyn | |
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Entrez Gene |
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Ensembl Gene |
| Genome Browser |
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NCBI Map Viewer |
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Vista |
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Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 621017 |
| Created: | 2002-08-06 |
| Species: | Rattus norvegicus |
| Last Modified: | 2013-04-16 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.