Gene: Thra (thyroid hormone receptor alpha) Rattus norvegicus
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Symbol: Thra
Name: thyroid hormone receptor alpha
Description: ENCODES a protein that exhibits intronic transcription regulatory region DNA binding; protein dimerization activity; protein heterodimerization activity; INVOLVED IN adrenal gland development; brain development; digestive tract development; ASSOCIATED WITH Hypertrophy, Left Ventricular; Breast Neoplasms (ortholog); Carcinoma, Renal Cell (ortholog); FOUND IN cytoplasm; cytosol; mitochondrion; INTERACTS WITH 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,4-dibromophenyl 2,4,5-tribromophenyl ether
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 1; c-erb-A thyroid hormone receptor; c-erbA-1; C-erbA-alpha; c-erbA-alpha2; c-erbAalpha2; ERBA1; nuclear receptor subfamily 1 group A member 1; Thra1; thyroid hormone receptor; Thyroid hormone receptor alpha 1 (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 1 formerly ERBA1); Thyroid hormone receptor, alpha 1 (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 1, formerly ERBA1)
Orthologs:
Homo sapiens (human) : THRA (thyroid hormone receptor, alpha)  HGNC  AGR
Mus musculus (house mouse) : Thra (thyroid hormone receptor alpha)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Thra (thyroid hormone receptor, alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : THRA (thyroid hormone receptor, alpha)
Canis lupus familiaris (dog) : THRA (thyroid hormone receptor, alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Thra (thyroid hormone receptor, alpha)
more info ...
Allele / Splice: Thra_v2   Thra_v1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01086,657,285 - 86,684,935 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01086,453,436 - 86,480,928 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41087,514,443 - 87,542,306 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11087,540,629 - 87,556,674 (+)NCBI
Celera1082,449,971 - 82,477,615 (+)NCBICelera
Cytogenetic Map10q31NCBI
RH 3.4 Map10839.79RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Thra
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3857
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE