Gene: Agtr1a (angiotensin II receptor, type 1a)  Rattus norvegicus

Symbol: Agtr1a
Name: angiotensin II receptor, type 1a
Description: ENCODES a protein that exhibits angiotensin type I receptor activity; G-protein alpha-subunit binding; peptide hormone binding; INVOLVED IN activation of Janus kinase activity; aging; cellular response to dexamethasone stimulus; PARTICIPATES IN angiotensin II signaling pathway via AT1 receptor; angiotensin III signaling pathway via AT1 receptor; G protein mediated signaling pathway via Galpha12/Galpha13 family; ASSOCIATED WITH increased left ventricle diastolic pressure; ASSOCIATED WITH Anti-Glomerular Basement Membrane Disease; Asthma; Cardiomegaly; FOUND IN basolateral plasma membrane; cytoplasmic vesicle; dendrite; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Agtr1; Angiotensin II receptor type 1 (AT1A); angiotensin II receptor, type 1; Angiotensin II receptor, type 1 (AT1A); angiotensin ii receptor, type 1 (at1a); angiotensin II receptor, type 1a; angiotensin II type-1A receptor; angiotensin receptor 1a; AT1; AT1A; AT1R; type-1A angiotensin II receptor; vascular type-1 angiotensin II receptor
Orthologs: Homo sapiens : AGTR1 (angiotensin II receptor, type 1)  HGNC
Allele / Splice: Agtr1aem5Mcwi   Agtr1aem1Mcwi  
Is Marker For: QTLs:   Bp343  
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map17q12 NCBI
RGSC Genome Assembly v5.01737,218,832 - 37,270,540-NCBI
RGSC Genome Assembly v3.41740,629,318 - 40,684,982-NCBI
Rat Celera Assembly1733,705,975 - 33,757,157-NCBI
Genome Assembly 3.11740,632,160 - 40,687,823-NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Agtr1a
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RGD Object Information
RGD ID: 2070
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE