Gene: Agtr1a (angiotensin II receptor, type 1a) Rattus norvegicus
Symbol: Agtr1a
Name: angiotensin II receptor, type 1a
Description: ENCODES a protein that exhibits angiotensin type I receptor activity; D1 dopamine receptor binding; G-protein alpha-subunit binding; INVOLVED IN activation of Janus kinase activity; aging; angiotensin-activated signaling pathway; PARTICIPATES IN angiotensin II signaling pathway via AT1 receptor; angiotensin III signaling pathway via AT1 receptor; G protein mediated signaling pathway via Galpha12/Galpha13 family; ASSOCIATED WITH Anti-Glomerular Basement Membrane Disease; Asthma; Cardiomegaly; FOUND IN basolateral plasma membrane; cytoplasmic vesicle; dendrite; INTERACTS WITH (R)-lipoic acid; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol
Type: protein-coding
Also known as: Agtr1; Angiotensin II receptor type 1 (AT1A); angiotensin II receptor, type 1; Angiotensin II receptor, type 1 (AT1A); angiotensin II type-1A receptor; angiotensin receptor 1a; AT1; AT1A; AT1R; type-1A angiotensin II receptor; vascular type-1 angiotensin II receptor
Allele / Splice: Agtr1aem5Mcwi   Agtr1aem1Mcwi  
Is Marker For: QTLs:   Bp343  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01735,906,084 - 35,958,132 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01737,217,810 - 37,270,540 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41740,629,318 - 40,684,982 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11740,632,160 - 40,687,823 (-)NCBI
Celera1733,705,975 - 33,757,157 (-)NCBI
Cytogenetic Map17q12NCBImapview

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Protein Structures

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Agtr1a
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 2070
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-05-10
Status: ACTIVE