Gene: Abcc1 (ATP binding cassette subfamily C member 1) Rattus norvegicus
Symbol: Abcc1
Name: ATP binding cassette subfamily C member 1
Description: ENCODES a protein that exhibits drug transmembrane transporter activity; efflux transmembrane transporter activity; glutathione S-conjugate-exporting ATPase activity; INVOLVED IN cell chemotaxis; daunorubicin transport; drug export; PARTICIPATES IN docetaxel pharmacodynamics pathway; doxorubicin pharmacokinetics pathway; irinotecan pharmacodynamics pathway; ASSOCIATED WITH Asthma (ortholog); Breast Cancer, Familial (ortholog); Breast Neoplasms (ortholog); FOUND IN basolateral plasma membrane; cytoplasm; integral component of plasma membrane; INTERACTS WITH (+)-pilocarpine; (R)-adrenaline; 17beta-estradiol 3-benzoate
Type: protein-coding
Also known as: Abcc1a; ATP-binding cassette sub-family C ( CFTR/MRP) member 1a; ATP-binding cassette sub-family C (CFTR/MRP) member 1 (multiple drug resistance-associated protein); ATP-binding cassette sub-family C member 1; ATP-binding cassette, sub-family C ( CFTR/MRP), member 1a; ATP-binding cassette, sub-family C (CFTR/MRP), member 1; ATP-binding cassette, sub-family C, member 1-like; ATP-binding cassette, subfamily C (CFTR/MRP), member 1; Avcc1a; leukotriene C(4) transporter; LOC100362747; LOC100365034; LTC4 transporter; Mrp; Mrp1; multidrug resistance protein; Multidrug resistance protein 1; multidrug resistance-associated protein 1; multidrug resistance-associated protein 1-like; multiple drug resistance-associated protein
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.010549,537 - 672,235 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01011,232,233 - 11,354,931 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.410452,239 - 575,705 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110452,238 - 575,705 (-)NCBI
Celera1011,130,945 - 11,246,232 (-)NCBI
Cytogenetic Map10q11NCBImapview

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Abcc1
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 3112
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-08-09
Status: ACTIVE