(S)-nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of HSD11B2 mRNA and Nicotine results in decreased expression of HSD11B2 protein CTD PMID:22265867 (S)-nicotine affects expression EXP 6480464 Nicotine affects the expression of HSD11B2 mRNA CTD PMID:31972234 (S)-nicotine increases expression ISO HSD11B2 (Homo sapiens) 6480464 Nicotine results in increased expression of HSD11B2 mRNA and Nicotine results in increased expression of HSD11B2 protein CTD PMID:29486207 (S)-nicotine increases expression EXP 6480464 Nicotine results in increased expression of HSD11B2 mRNA and Nicotine results in increased expression of HSD11B2 protein CTD PMID:29486207 (S)-nicotine multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3 more ... CTD PMID:29486207 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane decreases activity ISO HSD11B2 (Homo sapiens) 6480464 2 more ... CTD PMID:23333641 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane decreases activity EXP 6480464 2 more ... CTD PMID:23333641 1,1-dichloroethene decreases expression ISO Hsd11b2 (Mus musculus) 6480464 vinylidene chloride results in decreased expression of HSD11B2 mRNA CTD PMID:26682919 1,4-dithiothreitol multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Dithiothreitol inhibits the reaction [perfluorodecanoic acid results in decreased activity of HSD11B2 protein] more ... CTD PMID:12901862 more ... 1,4-dithiothreitol increases activity ISO HSD11B2 (Homo sapiens) 6480464 Dithiothreitol results in increased activity of HSD11B2 protein CTD PMID:36878351 1,4-dithiothreitol multiple interactions EXP 6480464 Dithiothreitol inhibits the reaction [Ziram results in decreased activity of HSD11B2 protein] CTD PMID:26859423 1,7-dimethylxanthine multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 1 more ... CTD PMID:22701600 1,7-dimethylxanthine decreases expression ISO HSD11B2 (Homo sapiens) 6480464 1 and 7-dimethylxanthine results in decreased expression of HSD11B2 mRNA CTD PMID:22701600 11-dehydrocorticosterone multiple interactions EXP 6480464 [HSD11B2 protein results in increased metabolism of Corticosterone] which results in increased chemical synthesis of 11-dehydrocorticosterone more ... CTD PMID:26859423 and PMID:32243540 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of HSD11B2 mRNA CTD PMID:12075121 more ... 17beta-estradiol decreases expression ISO HSD11B2 (Homo sapiens) 6480464 Estradiol results in decreased expression of HSD11B2 protein CTD PMID:17515840 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of HSD11B2 mRNA CTD PMID:32145629 17beta-estradiol multiple interactions ISO Hsd11b2 (Mus musculus) 6480464 [bisphenol A results in increased susceptibility to Estradiol] which results in decreased expression of HSD11B2 mRNA CTD PMID:27312807 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of HSD11B2 mRNA and [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of HSD11B2 mRNA CTD PMID:26496021 and PMID:32741896 17beta-estradiol increases expression ISO HSD11B2 (Homo sapiens) 6480464 Estradiol results in increased expression of HSD11B2 mRNA CTD PMID:23019147 17beta-estradiol multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [Estradiol binds to ESR2 protein] which results in increased expression of HSD11B2 mRNA more ... CTD PMID:20404318 more ... 17beta-estradiol 3-benzoate multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of HSD11B2 mRNA CTD PMID:32741896 2,2',4,4',5,5'-hexachlorobiphenyl decreases expression ISO HSD11B2 (Homo sapiens) 6480464 2 more ... CTD PMID:23146750 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Hsd11b2 (Mus musculus) 6480464 [2 more ... CTD PMID:25510870 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO HSD11B2 (Homo sapiens) 6480464 2 more ... CTD PMID:23146750 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Hsd11b2 (Mus musculus) 6480464 [2 more ... CTD PMID:25510870 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of HSD11B2 mRNA CTD PMID:22298810 2,4,6-trinitrotoluene affects expression EXP 6480464 Trinitrotoluene affects the expression of HSD11B2 mRNA CTD PMID:21346803 2,4-dinitrotoluene affects expression EXP 6480464 2 and 4-dinitrotoluene affects the expression of HSD11B2 mRNA CTD PMID:21346803 2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Itraconazole results in decreased activity of HSD11B2 protein CTD PMID:28131847 more ... 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine decreases activity EXP 6480464 Puromycin Aminonucleoside results in decreased activity of HSD11B2 protein CTD PMID:11981059 3,3',4,4',5-pentachlorobiphenyl decreases expression ISO HSD11B2 (Homo sapiens) 6480464 3 more ... CTD PMID:23146750 4,4'-sulfonyldiphenol increases expression ISO Hsd11b2 (Mus musculus) 6480464 bisphenol S results in increased expression of HSD11B2 mRNA CTD PMID:30951980 4,4'-sulfonyldiphenol decreases activity EXP 6480464 bisphenol S results in decreased activity of HSD11B2 protein CTD PMID:36871355 4,4'-sulfonyldiphenol increases expression ISO HSD11B2 (Homo sapiens) 6480464 bisphenol S results in increased expression of HSD11B2 mRNA and bisphenol S results in increased expression of HSD11B2 protein CTD PMID:30352284 4,4'-thiodiphenol decreases activity ISO HSD11B2 (Homo sapiens) 6480464 bis(4-oxyphenyl)sulfide results in decreased activity of HSD11B2 protein CTD PMID:36871355 4,4'-thiodiphenol decreases activity EXP 6480464 bis(4-oxyphenyl)sulfide results in decreased activity of HSD11B2 protein CTD PMID:36871355 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of HSD11B2 mRNA and Grape Seed Proanthocyanidins inhibits the reaction [[Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of HSD11B2 mRNA] CTD PMID:20146248 4-nonylphenol decreases activity ISO HSD11B2 (Homo sapiens) 6480464 4-nonylphenol results in decreased activity of HSD11B2 protein CTD PMID:16184081 4-octylphenol decreases activity ISO HSD11B2 (Homo sapiens) 6480464 4-octylphenol results in decreased activity of HSD11B2 protein CTD PMID:16184081 5-aza-2'-deoxycytidine increases expression ISO HSD11B2 (Homo sapiens) 6480464 Decitabine results in increased expression of HSD11B2 mRNA CTD PMID:15489962 5-aza-2'-deoxycytidine increases expression EXP 6480464 Decitabine results in increased expression of HSD11B2 mRNA CTD PMID:15489962 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of HSD11B2 mRNA CTD PMID:24780913 and PMID:30047161 8-Br-cAMP decreases expression ISO HSD11B2 (Homo sapiens) 6480464 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of HSD11B2 mRNA CTD PMID:22079614 8-Br-cAMP multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of HSD11B2 protein CTD PMID:23275455 actinomycin D multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Dactinomycin inhibits the reaction [Bexarotene results in increased expression of HSD11B2 mRNA] more ... CTD PMID:31927052 aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of HSD11B2 mRNA CTD PMID:23630614 aldehydo-D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of HSD11B2 mRNA CTD PMID:15017115 amitrole increases expression EXP 6480464 Amitrole results in increased expression of HSD11B2 mRNA CTD PMID:30047161 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of HSD11B2 mRNA CTD PMID:16483693 aristolochic acid A decreases expression ISO HSD11B2 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of HSD11B2 mRNA CTD PMID:33212167 arsenic acid increases expression ISO Hsd11b2 (Mus musculus) 6480464 arsenic acid results in increased expression of HSD11B2 mRNA CTD PMID:26855884 atrazine increases expression ISO HSD11B2 (Homo sapiens) 6480464 Atrazine results in increased expression of HSD11B2 mRNA CTD PMID:18461179 atrazine multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 NR5A1 protein promotes the reaction [Atrazine results in increased expression of HSD11B2 mRNA] and SGK1 protein affects the reaction [Atrazine results in increased expression of HSD11B2 mRNA] CTD PMID:18461179 azathioprine decreases expression ISO HSD11B2 (Homo sapiens) 6480464 Azathioprine results in decreased expression of HSD11B2 mRNA CTD PMID:22623647 azoxystrobin multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HSD11B2 mRNA CTD PMID:33854195 baicalein multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 12-Hydroxy-5 more ... CTD PMID:18032417 baicalein increases activity ISO HSD11B2 (Homo sapiens) 6480464 baicalein results in increased activity of HSD11B2 protein CTD PMID:18032417 beclomethasone increases metabolic processing ISO HSD11B2 (Homo sapiens) 6480464 HSD11B2 protein results in increased metabolism of Beclomethasone CTD PMID:16549198 benzo[a]pyrene increases expression ISO HSD11B2 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of HSD11B2 mRNA CTD PMID:24361490 benzo[a]pyrene decreases expression ISO HSD11B2 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of HSD11B2 mRNA CTD PMID:26238291 benzo[a]pyrene multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of HSD11B2 mRNA and Grape Seed Proanthocyanidins inhibits the reaction [[Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of HSD11B2 mRNA] CTD PMID:20146248 beta-naphthoflavone decreases expression ISO HSD11B2 (Homo sapiens) 6480464 beta-Naphthoflavone results in decreased expression of HSD11B2 mRNA CTD PMID:32858204 betamethasone multiple interactions EXP 6480464 Betamethasone inhibits the reaction [HSD11B2 protein affects the metabolism of Corticosterone] CTD PMID:19490994 betamethasone increases metabolic processing ISO HSD11B2 (Homo sapiens) 6480464 HSD11B2 protein results in increased metabolism of Betamethasone CTD PMID:16549198 bexarotene multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Bexarotene results in increased expression of and results in increased activity of HSD11B2 protein more ... CTD PMID:31927052 bexarotene increases expression ISO HSD11B2 (Homo sapiens) 6480464 Bexarotene results in increased expression of HSD11B2 mRNA CTD PMID:31927052 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of HSD11B2 mRNA CTD PMID:19560483 bisphenol A decreases activity EXP 6480464 bisphenol A results in decreased activity of HSD11B2 protein CTD PMID:23069880 and PMID:36871355 bisphenol A affects expression ISO HSD11B2 (Homo sapiens) 6480464 bisphenol A affects the expression of HSD11B2 mRNA CTD PMID:35220427 bisphenol A affects methylation ISO HSD11B2 (Homo sapiens) 6480464 bisphenol A affects the methylation of HSD11B2 gene CTD PMID:31601247 bisphenol A increases expression ISO Hsd11b2 (Mus musculus) 6480464 bisphenol A results in increased expression of HSD11B2 mRNA CTD PMID:30951980 bisphenol A multiple interactions ISO Hsd11b2 (Mus musculus) 6480464 [bisphenol A results in increased susceptibility to Estradiol] which results in decreased expression of HSD11B2 mRNA CTD PMID:27312807 bisphenol A increases methylation ISO Hsd11b2 (Mus musculus) 6480464 bisphenol A results in increased methylation of HSD11B2 promoter CTD PMID:27312807 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of HSD11B2 mRNA CTD PMID:12075121 more ... bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of HSD11B2 mRNA CTD PMID:26496021 bisphenol A decreases expression ISO Hsd11b2 (Mus musculus) 6480464 bisphenol A results in decreased expression of HSD11B2 mRNA CTD PMID:26063408 bisphenol A increases expression ISO HSD11B2 (Homo sapiens) 6480464 bisphenol A results in increased expression of HSD11B2 mRNA and bisphenol A results in increased expression of HSD11B2 protein CTD PMID:25784278 and PMID:30352284 bisphenol A multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 bisphenol A results in increased expression of and results in increased activity of HSD11B2 protein CTD PMID:25784278 bisphenol A decreases expression ISO HSD11B2 (Homo sapiens) 6480464 bisphenol A results in decreased expression of HSD11B2 mRNA CTD PMID:23146750 bisphenol A decreases activity ISO HSD11B2 (Homo sapiens) 6480464 bisphenol A results in decreased activity of HSD11B2 protein CTD PMID:23069880 and PMID:36871355 Bisphenol B decreases activity ISO HSD11B2 (Homo sapiens) 6480464 bisphenol B results in decreased activity of HSD11B2 protein CTD PMID:36871355 Bisphenol B decreases activity EXP 6480464 bisphenol B results in decreased activity of HSD11B2 protein CTD PMID:36871355 bisphenol F increases expression ISO Hsd11b2 (Mus musculus) 6480464 bisphenol F results in increased expression of HSD11B2 mRNA CTD PMID:30951980 bisphenol F decreases activity EXP 6480464 bisphenol F results in decreased activity of HSD11B2 protein CTD PMID:36871355 bromobenzene decreases expression EXP 6480464 bromobenzene results in decreased expression of HSD11B2 mRNA CTD PMID:32479839 C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of HSD11B2 mRNA CTD PMID:19167457 cadmium atom increases activity ISO HSD11B2 (Homo sapiens) 6480464 Cadmium results in increased activity of HSD11B2 protein CTD PMID:20624455 cadmium atom multiple interactions ISO Hsd11b2 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HSD11B2 mRNA CTD PMID:37325564 cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSD11B2 mRNA more ... CTD PMID:35384129 cadmium atom decreases expression ISO HSD11B2 (Homo sapiens) 6480464 Cadmium results in decreased expression of HSD11B2 mRNA CTD PMID:16144812 and PMID:23966319 cadmium atom multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSD11B2 mRNA more ... CTD PMID:16144812 more ... cadmium atom decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Cadmium results in decreased activity of HSD11B2 protein CTD PMID:22796344 and PMID:23880315 cadmium atom increases expression ISO HSD11B2 (Homo sapiens) 6480464 Cadmium results in increased expression of HSD11B2 mRNA CTD PMID:20624455 cadmium atom decreases methylation ISO HSD11B2 (Homo sapiens) 6480464 Cadmium results in decreased methylation of HSD11B2 promoter CTD PMID:20624455 cadmium dichloride multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSD11B2 mRNA more ... CTD PMID:35384129 cadmium dichloride multiple interactions ISO Hsd11b2 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HSD11B2 mRNA CTD PMID:37325564 cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSD11B2 mRNA more ... CTD PMID:35384129 caffeine decreases expression EXP 6480464 Caffeine results in decreased expression of HSD11B2 mRNA CTD PMID:22583948 more ... caffeine multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 ADORA2B mutant form inhibits the reaction [Caffeine results in decreased expression of and results in decreased activity of HSD11B2 protein] more ... CTD PMID:22701600 caffeine decreases expression ISO HSD11B2 (Homo sapiens) 6480464 Caffeine results in decreased expression of HSD11B2 mRNA CTD PMID:22701600 calcitriol increases expression ISO HSD11B2 (Homo sapiens) 6480464 Calcitriol results in increased expression of HSD11B2 mRNA CTD PMID:21592394 calcitriol multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of HSD11B2 mRNA CTD PMID:21592394 CARBENOXOLONE decreases activity ISO Hsd11b2 (Mus musculus) 6480464 Carbenoxolone results in decreased activity of HSD11B2 protein CTD PMID:24135201 CARBENOXOLONE decreases activity EXP 6480464 Carbenoxolone results in decreased activity of HSD11B2 protein CTD PMID:23814014 CARBENOXOLONE decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Carbenoxolone results in decreased activity of HSD11B2 protein CTD PMID:16857225 and PMID:24135201 CGP 52608 multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to HSD11B2 gene] CTD PMID:28238834 chloroprene decreases expression EXP 6480464 Chloroprene results in decreased expression of HSD11B2 mRNA CTD PMID:23125180 chlorpyrifos multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HSD11B2 mRNA CTD PMID:33854195 colforsin daropate hydrochloride multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Colforsin inhibits the reaction [1 more ... CTD PMID:22701600 and PMID:29802914 colforsin daropate hydrochloride increases expression ISO HSD11B2 (Homo sapiens) 6480464 Colforsin results in increased expression of HSD11B2 mRNA and Colforsin results in increased expression of HSD11B2 protein CTD PMID:24361490 more ... copper atom decreases expression EXP 6480464 Copper results in decreased expression of HSD11B2 mRNA CTD PMID:30556269 copper(0) decreases expression EXP 6480464 Copper results in decreased expression of HSD11B2 mRNA CTD PMID:30556269 copper(II) sulfate decreases expression ISO HSD11B2 (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of HSD11B2 mRNA CTD PMID:19549813 corticosterone multiple interactions EXP 6480464 [HSD11B2 protein results in increased metabolism of Corticosterone] which results in increased chemical synthesis of 11-dehydrocorticosterone more ... CTD PMID:19490994 more ... corticosterone increases oxidation EXP 6480464 HSD11B2 protein results in increased oxidation of Corticosterone CTD PMID:26859423 corticosterone increases metabolic processing ISO Hsd11b2 (Mus musculus) 6480464 HSD11B2 protein results in increased metabolism of Corticosterone CTD PMID:22796344 corticosterone affects metabolic processing EXP 6480464 HSD11B2 protein affects the metabolism of Corticosterone CTD PMID:19490994 cortisol affects binding ISO HSD11B2 (Homo sapiens) 6480464 HSD11B2 protein binds to Hydrocortisone CTD PMID:22273746 cortisol increases oxidation ISO HSD11B2 (Homo sapiens) 6480464 HSD11B2 protein results in increased oxidation of Hydrocortisone CTD PMID:26859423 cortisol multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [HSD11B2 protein results in increased oxidation of Hydrocortisone] which results in increased chemical synthesis of Cortisone more ... CTD PMID:26859423 and PMID:30528684 cortisol increases metabolic processing ISO HSD11B2 (Homo sapiens) 6480464 HSD11B2 protein results in increased metabolism of Hydrocortisone CTD PMID:22796344 cortisol decreases expression ISO HSD11B2 (Homo sapiens) 6480464 Hydrocortisone results in decreased expression of HSD11B2 mRNA and Hydrocortisone results in decreased expression of HSD11B2 protein CTD PMID:30528684 cortisone increases chemical synthesis ISO HSD11B2 (Homo sapiens) 6480464 HSD11B2 protein results in increased chemical synthesis of Cortisone CTD PMID:22796344 cortisone multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [HSD11B2 protein results in increased oxidation of Hydrocortisone] which results in increased chemical synthesis of Cortisone and Ziram inhibits the reaction [[HSD11B2 protein results in increased oxidation of Hydrocortisone] which results in increased chemical synthesis of Cortisone] CTD PMID:26859423 cosyntropin decreases expression ISO HSD11B2 (Homo sapiens) 6480464 Cosyntropin results in decreased expression of HSD11B2 protein CTD PMID:11082157 cycloheximide multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Cycloheximide promotes the reaction [Bexarotene results in increased expression of HSD11B2 mRNA] more ... CTD PMID:31927052 cyclosporin A decreases expression ISO HSD11B2 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of HSD11B2 mRNA CTD PMID:25562108 cypermethrin increases expression ISO Hsd11b2 (Mus musculus) 6480464 cypermethrin results in increased expression of HSD11B2 mRNA CTD PMID:35031408 D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of HSD11B2 mRNA CTD PMID:15017115 danazol decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Danazol results in decreased activity of HSD11B2 protein CTD PMID:22273746 danazol multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Danazol inhibits the reaction [HSD11B2 protein results in decreased activity of Glucocorticoids] CTD PMID:22273746 dexamethasone increases expression ISO HSD11B2 (Homo sapiens) 6480464 Dexamethasone results in increased expression of HSD11B2 mRNA and Dexamethasone results in increased expression of HSD11B2 protein CTD PMID:15679045 dexamethasone increases expression ISO Hsd11b2 (Mus musculus) 6480464 Dexamethasone results in increased expression of HSD11B2 mRNA CTD PMID:29624291 dexamethasone increases metabolic processing ISO HSD11B2 (Homo sapiens) 6480464 HSD11B2 protein results in increased metabolism of Dexamethasone CTD PMID:16549198 dexamethasone multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [HSD11B2 protein affects the metabolism of Corticosterone] CTD PMID:19490994 dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of HSD11B2 mRNA CTD PMID:19490994 dexamethasone multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Thiram inhibits the reaction [HSD11B2 protein results in increased oxidation of Dexamethasone] CTD PMID:16857225 dexamethasone increases oxidation ISO HSD11B2 (Homo sapiens) 6480464 HSD11B2 protein results in increased oxidation of Dexamethasone CTD PMID:16857225 dextran sulfate multiple interactions ISO Hsd11b2 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of HSD11B2 mRNA CTD PMID:29950665 dibutyl phthalate decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Dibutyl Phthalate results in decreased activity of HSD11B2 protein CTD PMID:19786001 dibutyl phthalate decreases expression ISO Hsd11b2 (Mus musculus) 6480464 Dibutyl Phthalate results in decreased expression of HSD11B2 mRNA CTD PMID:17361019 and PMID:21266533 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of HSD11B2 mRNA CTD PMID:19560483 and PMID:21266533 dibutyl phthalate decreases activity EXP 6480464 Dibutyl Phthalate results in decreased activity of HSD11B2 protein CTD PMID:19786001 dibutylstannane decreases activity ISO HSD11B2 (Homo sapiens) 6480464 di-n-butyltin results in decreased activity of HSD11B2 protein CTD PMID:22796344 dicrotophos increases expression ISO HSD11B2 (Homo sapiens) 6480464 dicrotophos results in increased expression of HSD11B2 mRNA CTD PMID:28302478 Dicyclohexyl phthalate decreases activity EXP 6480464 dicyclohexyl phthalate results in decreased activity of HSD11B2 protein CTD PMID:19786001 Dicyclohexyl phthalate decreases activity ISO HSD11B2 (Homo sapiens) 6480464 dicyclohexyl phthalate results in decreased activity of HSD11B2 protein CTD PMID:16184081 diethyldithiocarbamic acid decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Ditiocarb results in decreased activity of HSD11B2 protein CTD PMID:22796344 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of HSD11B2 mRNA CTD PMID:21658437 dioxygen decreases expression EXP 6480464 Oxygen deficiency results in decreased expression of HSD11B2 mRNA and Oxygen deficiency results in decreased expression of HSD11B2 protein CTD PMID:35378222 dioxygen increases methylation EXP 6480464 Oxygen deficiency results in increased methylation of HSD11B2 promoter CTD PMID:35378222 dipentyl phthalate decreases expression EXP 6480464 di-n-pentyl phthalate results in decreased expression of HSD11B2 mRNA CTD PMID:19560483 diphenylstannane decreases activity ISO HSD11B2 (Homo sapiens) 6480464 diphenyltin results in decreased activity of HSD11B2 protein CTD PMID:22796344 dipropyl phthalate decreases activity ISO HSD11B2 (Homo sapiens) 6480464 di-n-propylphthalate results in decreased activity of HSD11B2 protein CTD PMID:19786001 dipropyl phthalate decreases activity EXP 6480464 di-n-propylphthalate results in decreased activity of HSD11B2 protein CTD PMID:19786001 disodium selenite multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSD11B2 mRNA] and [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSD11B2 protein] CTD PMID:35384129 disodium selenite multiple interactions EXP 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSD11B2 mRNA] more ... CTD PMID:35384129 disulfiram decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Disulfiram results in decreased activity of HSD11B2 protein CTD PMID:22796344 docebenone increases activity ISO HSD11B2 (Homo sapiens) 6480464 2 more ... CTD PMID:18032417 docebenone multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [2 more ... CTD PMID:18032417 dorsomorphin multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin decreases activity EXP 6480464 Doxorubicin results in decreased activity of HSD11B2 protein CTD PMID:11981059 elemental selenium multiple interactions EXP 6480464 [Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of HSD11B2 mRNA more ... CTD PMID:11444866 and PMID:35384129 elemental selenium multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSD11B2 mRNA] and [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSD11B2 protein] CTD PMID:35384129 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of HSD11B2 mRNA CTD PMID:29391264 entinostat multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HSD11B2 mRNA CTD PMID:27188386 entinostat increases expression ISO HSD11B2 (Homo sapiens) 6480464 entinostat results in increased expression of HSD11B2 mRNA CTD PMID:26272509 and PMID:27188386 ethanol increases expression EXP 6480464 Ethanol results in increased expression of HSD11B2 mRNA CTD PMID:32437893 ethanol multiple interactions EXP 6480464 Ethanol affects the reaction [Dietary Fats affects the expression of HSD11B2 mRNA] CTD PMID:31811911 ethanol decreases expression ISO HSD11B2 (Homo sapiens) 6480464 Ethanol results in decreased expression of HSD11B2 mRNA and Ethanol results in decreased expression of HSD11B2 protein CTD PMID:29802914 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of HSD11B2 mRNA and Ethanol results in decreased expression of HSD11B2 protein CTD PMID:29802914 ethanol multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Colforsin inhibits the reaction [Ethanol results in decreased expression of HSD11B2 mRNA] more ... CTD PMID:29802914 ethanol affects expression EXP 6480464 Ethanol affects the expression of HSD11B2 mRNA CTD PMID:31039417 and PMID:32535229 ethylparaben decreases expression ISO HSD11B2 (Homo sapiens) 6480464 ethyl-p-hydroxybenzoate results in decreased expression of HSD11B2 mRNA CTD PMID:37690743 fentin chloride multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [triphenyltin chloride results in increased activity of HSD11B2 protein] more ... CTD PMID:31927052 fentin chloride increases expression ISO HSD11B2 (Homo sapiens) 6480464 triphenyltin chloride results in increased expression of HSD11B2 mRNA CTD PMID:31927052 fludioxonil increases activity ISO HSD11B2 (Homo sapiens) 6480464 fludioxonil results in increased activity of HSD11B2 protein CTD PMID:31927052 fluoxymesterone multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Fluoxymesterone inhibits the reaction [HSD11B2 protein results in decreased activity of Glucocorticoids] and HSD11B2 protein binds to and results in increased metabolism of Fluoxymesterone CTD PMID:22273746 fluoxymesterone decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Fluoxymesterone results in decreased activity of HSD11B2 protein CTD PMID:22273746 flurbiprofen increases expression ISO Hsd11b2 (Mus musculus) 6480464 Flurbiprofen results in increased expression of HSD11B2 mRNA CTD PMID:16949054 genistein increases expression EXP 6480464 Genistein results in increased expression of HSD11B2 mRNA CTD PMID:12075121 genistein increases expression ISO HSD11B2 (Homo sapiens) 6480464 Genistein results in increased expression of HSD11B2 mRNA CTD PMID:23019147 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of HSD11B2 mRNA CTD PMID:22061828 glucose decreases expression EXP 6480464 Glucose results in decreased expression of HSD11B2 mRNA CTD PMID:15017115 glycyrrhetinate decreases activity ISO HSD11B2 (Homo sapiens) 6480464 18alpha-glycyrrhetinic acid results in decreased activity of HSD11B2 protein CTD PMID:24135201 glycyrrhetinate multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Glycyrrhetinic Acid inhibits the reaction [tributyltin results in increased activity of HSD11B2 protein] and Glycyrrhetinic Acid inhibits the reaction [triphenyltin chloride results in increased activity of HSD11B2 protein] CTD PMID:31927052 glycyrrhetinate decreases activity ISO Hsd11b2 (Mus musculus) 6480464 18alpha-glycyrrhetinic acid results in decreased activity of HSD11B2 protein CTD PMID:24135201 glycyrrhetinic acid decreases activity ISO HSD11B2 (Homo sapiens) 6480464 18alpha-glycyrrhetinic acid results in decreased activity of HSD11B2 protein CTD PMID:24135201 glycyrrhetinic acid multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Glycyrrhetinic Acid inhibits the reaction [tributyltin results in increased activity of HSD11B2 protein] and Glycyrrhetinic Acid inhibits the reaction [triphenyltin chloride results in increased activity of HSD11B2 protein] CTD PMID:31927052 glycyrrhetinic acid decreases activity ISO Hsd11b2 (Mus musculus) 6480464 18alpha-glycyrrhetinic acid results in decreased activity of HSD11B2 protein CTD PMID:24135201 glycyrrhizinic acid decreases expression EXP 6480464 Glycyrrhizic Acid results in decreased expression of HSD11B2 mRNA CTD PMID:10474021 and PMID:11798659 glyphosate multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HSD11B2 mRNA CTD PMID:33854195 hydrogen peroxide affects expression ISO HSD11B2 (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of HSD11B2 mRNA CTD PMID:23410634 hydroxyitraconazole decreases activity ISO HSD11B2 (Homo sapiens) 6480464 hydroxyitraconazole results in decreased activity of HSD11B2 protein CTD PMID:28131847 and PMID:33387577 imidacloprid multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HSD11B2 mRNA CTD PMID:33854195 indometacin decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Indomethacin results in decreased activity of HSD11B2 protein CTD PMID:10377029 itraconazole decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Itraconazole results in decreased activity of HSD11B2 protein CTD PMID:28131847 more ... ketoconazole decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Ketoconazole results in decreased activity of HSD11B2 protein CTD PMID:10664531 L-1,4-dithiothreitol multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Dithiothreitol inhibits the reaction [perfluorodecanoic acid results in decreased activity of HSD11B2 protein] more ... CTD PMID:12901862 more ... L-1,4-dithiothreitol increases activity ISO HSD11B2 (Homo sapiens) 6480464 Dithiothreitol results in increased activity of HSD11B2 protein CTD PMID:36878351 L-1,4-dithiothreitol multiple interactions EXP 6480464 Dithiothreitol inhibits the reaction [Ziram results in decreased activity of HSD11B2 protein] CTD PMID:26859423 leflunomide decreases expression EXP 6480464 leflunomide results in decreased expression of HSD11B2 mRNA CTD PMID:24136188 leukotriene B4 multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [2 more ... CTD PMID:18032417 leukotriene B4 decreases expression ISO HSD11B2 (Homo sapiens) 6480464 Leukotriene B4 results in decreased expression of HSD11B2 mRNA CTD PMID:18032417 leukotriene B4 decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Leukotriene B4 results in decreased activity of HSD11B2 protein CTD PMID:10377029 and PMID:18032417 lithium atom increases expression EXP 6480464 Lithium results in increased expression of HSD11B2 mRNA and Lithium results in increased expression of HSD11B2 protein CTD PMID:15687245 lithium hydride increases expression EXP 6480464 Lithium results in increased expression of HSD11B2 mRNA and Lithium results in increased expression of HSD11B2 protein CTD PMID:15687245 maneb decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Maneb results in decreased activity of HSD11B2 protein CTD PMID:22796344 masoprocol multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 12-Hydroxy-5 more ... CTD PMID:18032417 masoprocol increases expression ISO HSD11B2 (Homo sapiens) 6480464 Masoprocol results in increased expression of HSD11B2 mRNA CTD PMID:18032417 masoprocol increases activity ISO HSD11B2 (Homo sapiens) 6480464 Masoprocol results in increased activity of HSD11B2 protein CTD PMID:10377029 and PMID:18032417 medroxyprogesterone acetate multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of HSD11B2 protein CTD PMID:23275455 menadione affects expression ISO HSD11B2 (Homo sapiens) 6480464 Vitamin K 3 affects the expression of HSD11B2 mRNA CTD PMID:23410634 mercury dichloride decreases expression EXP 6480464 Mercuric Chloride results in decreased expression of HSD11B2 protein CTD PMID:16189294 methimazole increases expression EXP 6480464 Methimazole results in increased expression of HSD11B2 mRNA CTD PMID:30047161 metyrapone decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Metyrapone results in decreased activity of HSD11B2 protein CTD PMID:10664531 mifepristone multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Masoprocol promotes the reaction [Mifepristone results in increased activity of HSD11B2 protein] more ... CTD PMID:18032417 and PMID:30528684 mifepristone increases expression ISO HSD11B2 (Homo sapiens) 6480464 Mifepristone results in increased expression of HSD11B2 mRNA and Mifepristone results in increased expression of HSD11B2 protein CTD PMID:18032417 mono(2-ethylhexyl) phthalate decreases activity ISO HSD11B2 (Homo sapiens) 6480464 mono-(2-ethylhexyl)phthalate results in decreased activity of HSD11B2 protein CTD PMID:19786001 mono(2-ethylhexyl) phthalate decreases expression ISO Hsd11b2 (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of HSD11B2 mRNA CTD PMID:37886449 mono(2-ethylhexyl) phthalate affects expression ISO Hsd11b2 (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate affects the expression of HSD11B2 mRNA CTD PMID:21195148 mono(2-ethylhexyl) phthalate decreases activity EXP 6480464 mono-(2-ethylhexyl)phthalate results in decreased activity of HSD11B2 protein CTD PMID:19786001 Monobutylphthalate affects expression ISO Hsd11b2 (Mus musculus) 6480464 monobutyl phthalate affects the expression of HSD11B2 mRNA CTD PMID:21195148 N-acetyl-L-cysteine multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of HSD11B2 mRNA] CTD PMID:18829485 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Progesterone results in increased expression of HSD11B2 mRNA] CTD PMID:15857753 N-ethylmaleimide multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Ethylmaleimide promotes the reaction [Thiram results in decreased activity of HSD11B2 protein] CTD PMID:22796344 N-Nitrosopyrrolidine increases expression ISO HSD11B2 (Homo sapiens) 6480464 N-Nitrosopyrrolidine results in increased expression of HSD11B2 mRNA CTD PMID:32234424 NAD zwitterion multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Ziram inhibits the reaction [HSD11B2 protein results in increased reduction of NAD] CTD PMID:26859423 NAD zwitterion increases reduction ISO HSD11B2 (Homo sapiens) 6480464 HSD11B2 protein results in increased reduction of NAD CTD PMID:26859423 NAD zwitterion increases reduction EXP 6480464 HSD11B2 protein results in increased reduction of NAD CTD PMID:26859423 NAD zwitterion multiple interactions EXP 6480464 Ziram inhibits the reaction [HSD11B2 protein results in increased reduction of NAD] CTD PMID:26859423 NAD(+) increases reduction ISO HSD11B2 (Homo sapiens) 6480464 HSD11B2 protein results in increased reduction of NAD CTD PMID:26859423 NAD(+) increases reduction EXP 6480464 HSD11B2 protein results in increased reduction of NAD CTD PMID:26859423 NAD(+) multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Ziram inhibits the reaction [HSD11B2 protein results in increased reduction of NAD] CTD PMID:26859423 NAD(+) multiple interactions EXP 6480464 Ziram inhibits the reaction [HSD11B2 protein results in increased reduction of NAD] CTD PMID:26859423 NADP zwitterion multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 NADP binds to and results in increased activity of HSD11B2 protein CTD PMID:25526675 NADP(+) multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 NADP binds to and results in increased activity of HSD11B2 protein CTD PMID:25526675 nickel atom decreases expression ISO HSD11B2 (Homo sapiens) 6480464 Nickel results in decreased expression of HSD11B2 mRNA CTD PMID:24768652 and PMID:25583101 nicotine multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3 more ... CTD PMID:29486207 nicotine affects expression EXP 6480464 Nicotine affects the expression of HSD11B2 mRNA CTD PMID:31972234 nicotine increases expression EXP 6480464 Nicotine results in increased expression of HSD11B2 mRNA and Nicotine results in increased expression of HSD11B2 protein CTD PMID:29486207 nicotine increases expression ISO HSD11B2 (Homo sapiens) 6480464 Nicotine results in increased expression of HSD11B2 mRNA and Nicotine results in increased expression of HSD11B2 protein CTD PMID:29486207 nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of HSD11B2 mRNA and Nicotine results in decreased expression of HSD11B2 protein CTD PMID:22265867 oxymetholone multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Oxymetholone inhibits the reaction [HSD11B2 protein results in decreased activity of Glucocorticoids] CTD PMID:22273746 oxymetholone decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Oxymetholone results in decreased activity of HSD11B2 protein CTD PMID:22273746 ozone multiple interactions ISO Hsd11b2 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of HSD11B2 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of HSD11B2 mRNA CTD PMID:34911549 paracetamol decreases expression ISO Hsd11b2 (Mus musculus) 6480464 Acetaminophen results in decreased expression of HSD11B2 mRNA CTD PMID:17585979 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of HSD11B2 mRNA CTD PMID:33387578 paracetamol increases expression ISO HSD11B2 (Homo sapiens) 6480464 Acetaminophen results in increased expression of HSD11B2 mRNA CTD PMID:26690555 paracetamol decreases expression ISO HSD11B2 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of HSD11B2 mRNA CTD PMID:29067470 paracetamol affects expression ISO Hsd11b2 (Mus musculus) 6480464 Acetaminophen affects the expression of HSD11B2 mRNA CTD PMID:17562736 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of HSD11B2 mRNA CTD PMID:32680482 PCB138 multiple interactions ISO Hsd11b2 (Mus musculus) 6480464 [2 more ... CTD PMID:25510870 perfluorodecanoic acid multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Dithiothreitol inhibits the reaction [perfluorodecanoic acid results in decreased activity of HSD11B2 protein] and perfluorodecanoic acid inhibits the reaction [Dithiothreitol results in increased activity of HSD11B2 protein] CTD PMID:36878351 perfluorodecanoic acid decreases activity ISO HSD11B2 (Homo sapiens) 6480464 perfluorodecanoic acid results in decreased activity of HSD11B2 protein CTD PMID:36878351 perfluorododecanoic acid decreases activity ISO HSD11B2 (Homo sapiens) 6480464 perfluorododecanoic acid results in decreased activity of HSD11B2 protein CTD PMID:36878351 perfluorononanoic acid decreases activity ISO HSD11B2 (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in decreased activity of HSD11B2 protein CTD PMID:36878351 perfluorooctane-1-sulfonic acid decreases activity ISO HSD11B2 (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in decreased activity of HSD11B2 protein CTD PMID:36878351 perfluorooctanoic acid decreases expression ISO HSD11B2 (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of HSD11B2 mRNA CTD PMID:23146750 perfluorooctanoic acid decreases activity ISO HSD11B2 (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased activity of HSD11B2 protein CTD PMID:36878351 perfluoroundecanoic acid decreases activity ISO HSD11B2 (Homo sapiens) 6480464 perfluoroundecanoic acid results in decreased activity of HSD11B2 protein CTD PMID:36878351 posaconazole decreases activity ISO HSD11B2 (Homo sapiens) 6480464 posaconazole results in decreased activity of HSD11B2 protein CTD PMID:28131847 and PMID:33387577 prednisolone increases metabolic processing ISO HSD11B2 (Homo sapiens) 6480464 HSD11B2 protein results in increased metabolism of Prednisolone CTD PMID:16549198 procainamide increases expression ISO HSD11B2 (Homo sapiens) 6480464 Procainamide results in increased expression of HSD11B2 mRNA CTD PMID:15489962 procainamide increases expression EXP 6480464 Procainamide results in increased expression of HSD11B2 mRNA CTD PMID:15489962 progesterone multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [Estradiol co-treated with Progesterone] results in increased expression of HSD11B2 mRNA more ... CTD PMID:15857753 more ... progesterone decreases expression ISO HSD11B2 (Homo sapiens) 6480464 Progesterone results in decreased expression of HSD11B2 mRNA and Progesterone results in decreased expression of HSD11B2 protein CTD PMID:18032417 more ... progesterone increases expression ISO HSD11B2 (Homo sapiens) 6480464 Progesterone results in increased expression of HSD11B2 mRNA CTD PMID:15857753 progesterone decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Progesterone results in decreased activity of HSD11B2 protein CTD PMID:18032417 prostaglandin E2 decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Dinoprostone results in decreased activity of HSD11B2 protein CTD PMID:10377029 prostaglandin F2alpha decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Dinoprost results in decreased activity of HSD11B2 protein CTD PMID:10377029 prostaglandin F2alpha decreases expression EXP 6480464 Dinoprost results in decreased expression of HSD11B2 mRNA CTD PMID:11517196 pyrrolidine dithiocarbamate decreases activity ISO HSD11B2 (Homo sapiens) 6480464 pyrrolidine dithiocarbamic acid results in decreased activity of HSD11B2 protein CTD PMID:22796344 quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of HSD11B2 protein CTD PMID:18095365 resveratrol multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of HSD11B2 mRNA CTD PMID:23557933 SB 431542 multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 selenium atom multiple interactions EXP 6480464 [Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of HSD11B2 mRNA more ... CTD PMID:11444866 and PMID:35384129 selenium atom multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSD11B2 mRNA] and [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSD11B2 protein] CTD PMID:35384129 silicon dioxide decreases expression ISO HSD11B2 (Homo sapiens) 6480464 Silicon Dioxide results in decreased expression of HSD11B2 mRNA CTD PMID:25351596 silicon dioxide increases expression ISO Hsd11b2 (Mus musculus) 6480464 Silicon Dioxide results in increased expression of HSD11B2 mRNA CTD PMID:29341224 sodium arsenate decreases expression ISO HSD11B2 (Homo sapiens) 6480464 sodium arsenate results in decreased expression of HSD11B2 mRNA CTD PMID:12727804 sodium arsenite decreases expression ISO HSD11B2 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of HSD11B2 mRNA CTD PMID:12727804 sodium arsenite increases expression ISO HSD11B2 (Homo sapiens) 6480464 sodium arsenite results in increased expression of HSD11B2 mRNA CTD PMID:34032870 sodium chloride decreases activity EXP 6480464 Sodium Chloride results in decreased activity of HSD11B2 protein CTD PMID:12943734 sodium chloride decreases expression EXP 6480464 Sodium Chloride results in decreased expression of HSD11B2 mRNA CTD PMID:12943734 spironolactone decreases expression EXP 6480464 Spironolactone results in decreased expression of HSD11B2 mRNA CTD PMID:17587755 sulfadimethoxine increases expression EXP 6480464 Sulfadimethoxine results in increased expression of HSD11B2 mRNA CTD PMID:30047161 tert-butyl hydroperoxide affects expression ISO HSD11B2 (Homo sapiens) 6480464 tert-Butylhydroperoxide affects the expression of HSD11B2 mRNA CTD PMID:23410634 testosterone multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of HSD11B2 mRNA and Testosterone inhibits the reaction [HSD11B2 protein results in decreased activity of Glucocorticoids] CTD PMID:21592394 and PMID:22273746 testosterone multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of HSD11B2 mRNA CTD PMID:32741896 testosterone decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Testosterone results in decreased activity of HSD11B2 protein CTD PMID:22273746 testosterone increases expression ISO HSD11B2 (Homo sapiens) 6480464 Testosterone results in increased expression of HSD11B2 mRNA CTD PMID:21592394 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of HSD11B2 mRNA and Carbon Tetrachloride results in decreased expression of HSD11B2 protein CTD PMID:16192424 and PMID:31150632 thalidomide decreases expression ISO Hsd11b2 (Mus musculus) 6480464 Thalidomide results in decreased expression of HSD11B2 mRNA CTD PMID:26217789 thiabendazole multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HSD11B2 mRNA CTD PMID:33854195 thiram multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Dithiothreitol inhibits the reaction [Thiram results in decreased activity of HSD11B2 protein] more ... CTD PMID:12901862 more ... thiram decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Thiram results in decreased activity of HSD11B2 protein CTD PMID:12901862 more ... titanium dioxide multiple interactions ISO Hsd11b2 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of HSD11B2 mRNA CTD PMID:29950665 tributylstannane decreases activity ISO HSD11B2 (Homo sapiens) 6480464 tributyltin results in decreased activity of HSD11B2 protein CTD PMID:16184081 and PMID:22796344 tributylstannane increases expression ISO HSD11B2 (Homo sapiens) 6480464 tributyltin results in increased expression of HSD11B2 mRNA CTD PMID:31927052 tributylstannane multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Cycloheximide promotes the reaction [tributyltin results in increased expression of HSD11B2 mRNA] more ... CTD PMID:31927052 trichloroethene increases methylation EXP 6480464 Trichloroethylene results in increased methylation of HSD11B2 gene CTD PMID:27618143 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of HSD11B2 mRNA CTD PMID:33387578 trichostatin A increases expression ISO HSD11B2 (Homo sapiens) 6480464 trichostatin A results in increased expression of HSD11B2 mRNA CTD PMID:24935251 triphenyl phosphate multiple interactions EXP 6480464 [triphenyl phosphate co-treated with Flame Retardants] results in decreased expression of HSD11B2 mRNA CTD PMID:32243540 triphenylstannane decreases activity ISO HSD11B2 (Homo sapiens) 6480464 triphenyltin results in decreased activity of HSD11B2 protein CTD PMID:16184081 and PMID:22796344 triphenylstannane increases expression EXP 6480464 triphenyltin results in increased expression of HSD11B2 mRNA and triphenyltin results in increased expression of HSD11B2 protein CTD PMID:31765896 triptonide increases expression ISO Hsd11b2 (Mus musculus) 6480464 triptonide results in increased expression of HSD11B2 mRNA CTD PMID:33045310 urethane decreases expression ISO HSD11B2 (Homo sapiens) 6480464 Urethane results in decreased expression of HSD11B2 mRNA CTD PMID:28818685 valproic acid increases expression ISO HSD11B2 (Homo sapiens) 6480464 Valproic Acid results in increased expression of HSD11B2 mRNA CTD PMID:23179753 and PMID:26272509 valproic acid decreases expression ISO HSD11B2 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of HSD11B2 mRNA CTD PMID:37505509 valproic acid multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HSD11B2 mRNA CTD PMID:27188386 vecuronium bromide increases expression ISO HSD11B2 (Homo sapiens) 6480464 Vecuronium Bromide results in increased expression of HSD11B2 mRNA and Vecuronium Bromide results in increased expression of HSD11B2 protein CTD PMID:29486207 vecuronium bromide multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of HSD11B2 mRNA] and Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of HSD11B2 protein] CTD PMID:29486207 vitamin E multiple interactions EXP 6480464 [Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of HSD11B2 mRNA CTD PMID:11444866 zileuton increases activity ISO HSD11B2 (Homo sapiens) 6480464 zileuton results in increased activity of HSD11B2 protein CTD PMID:10377029 zinc atom decreases expression EXP 6480464 Zinc deficiency results in decreased expression of HSD11B2 mRNA CTD PMID:15671213 zinc(0) decreases expression EXP 6480464 Zinc deficiency results in decreased expression of HSD11B2 mRNA CTD PMID:15671213 zineb decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Zineb results in decreased activity of HSD11B2 protein CTD PMID:22796344 ziram multiple interactions ISO HSD11B2 (Homo sapiens) 6480464 Dithiothreitol inhibits the reaction [Ziram results in decreased activity of HSD11B2 protein] more ... CTD PMID:26859423 ziram multiple interactions EXP 6480464 Dithiothreitol inhibits the reaction [Ziram results in decreased activity of HSD11B2 protein] more ... CTD PMID:26859423 ziram decreases activity ISO HSD11B2 (Homo sapiens) 6480464 Ziram results in decreased activity of HSD11B2 protein CTD PMID:26859423 ziram decreases activity EXP 6480464 Ziram results in decreased activity of HSD11B2 protein CTD PMID:26859423 zoledronic acid decreases expression ISO HSD11B2 (Homo sapiens) 6480464 zoledronic acid results in decreased expression of HSD11B2 mRNA CTD PMID:24714768