Rpl11 (ribosomal protein L11) - Rat Genome Database

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Gene: Rpl11 (ribosomal protein L11) Rattus norvegicus
Analyze
Symbol: Rpl11
Name: ribosomal protein L11
RGD ID: 1308681
Description: Enables peroxisome proliferator activated receptor binding activity. Predicted to be involved in several processes, including negative regulation of protein metabolic process; protein stabilization; and ribosome biogenesis. Located in cytosolic ribosome. Part of cytosolic large ribosomal subunit. Is active in synapse. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 7 and T-cell acute lymphoblastic leukemia. Orthologous to human RPL11 (ribosomal protein L11); PARTICIPATES IN p53 signaling pathway; ribosome biogenesis pathway; translation pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 60S ribosomal protein L11; large ribosomal subunit protein uL5; LOC362631; MGC114407
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85153,557,592 - 153,561,230 (-)NCBIGRCr8
mRatBN7.25148,274,060 - 148,277,708 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5148,274,069 - 148,277,599 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5150,973,410 - 150,976,617 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05152,747,677 - 152,750,884 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05152,729,697 - 152,732,904 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05154,390,809 - 154,394,412 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5154,388,140 - 154,394,328 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05158,155,377 - 158,158,967 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45154,826,973 - 154,830,183 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15154,837,011 - 154,840,222 (-)NCBI
Celera5146,679,072 - 146,682,282 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Structures of the human and Drosophila 80S ribosome. Anger AM, etal., Nature. 2013 May 2;497(7447):80-5. doi: 10.1038/nature12104.
2. Identification of mutations in the ribosomal protein L5 (RPL5) and ribosomal protein L11 (RPL11) genes in Czech patients with Diamond-Blackfan anemia. Cmejla R, etal., Hum Mutat. 2009 Mar;30(3):321-7. doi: 10.1002/humu.20874.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Ribosomal protein L5 and L11 mutations are associated with cleft palate and abnormal thumbs in Diamond-Blackfan anemia patients. Gazda HT, etal., Am J Hum Genet. 2008 Dec;83(6):769-80. doi: 10.1016/j.ajhg.2008.11.004.
5. The ribosomal protein rpL11 associates with and inhibits the transcriptional activity of peroxisome proliferator-activated receptor-alpha. Gray JP, etal., Toxicol Sci. 2006 Feb;89(2):535-46. Epub 2005 Nov 9.
6. Mutations in the ribosomal protein genes in Japanese patients with Diamond-Blackfan anemia. Konno Y, etal., Haematologica. 2010 Aug;95(8):1293-9. doi: 10.3324/haematol.2009.020826. Epub 2010 Apr 7.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Partial Loss of Rpl11 in Adult Mice Recapitulates Diamond-Blackfan Anemia and Promotes Lymphomagenesis. Morgado-Palacin L, etal., Cell Rep. 2015 Oct 27;13(4):712-22. doi: 10.1016/j.celrep.2015.09.038. Epub 2015 Oct 17.
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. Semiquantitative proteomic analysis of rat forebrain postsynaptic density fractions by mass spectrometry. Peng J, etal., J Biol Chem. 2004 May 14;279(20):21003-11. doi: 10.1074/jbc.M400103200. Epub 2004 Mar 12.
11. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
12. Diamond-Blackfan anemia: genotype-phenotype correlations in Italian patients with RPL5 and RPL11 mutations. Quarello P, etal., Haematologica. 2010 Feb;95(2):206-13. doi: 10.3324/haematol.2009.011783. Epub 2009 Sep 22.
13. GOA pipeline RGD automated data pipeline
14. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. Clinical and genomic heterogeneity of Diamond Blackfan anemia in the Russian Federation. Smetanina NS, etal., Pediatr Blood Cancer. 2015 Sep;62(9):1597-600. doi: 10.1002/pbc.25534. Epub 2015 May 6.
17. Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL. Tzoneva G, etal., Nat Med. 2013 Mar;19(3):368-71. doi: 10.1038/nm.3078. Epub 2013 Feb 3.
18. Neighboring proteins in rat liver 60 S ribosomal subunits disulfide-linked by hydrogen peroxide oxidation or cross-linked with dithiobis(succinimidyl propionate). Uchiumi T, etal., J Biol Chem. 1985 May 10;260(9):5669-74.
19. Cross-linking study on protein neighborhoods at the subunit interface of rat liver ribosomes with 2-iminothiolane. Uchiumi T, etal., J Biol Chem. 1986 Jul 25;261(21):9663-7.
Additional References at PubMed
PMID:1599472   PMID:12477932   PMID:12962325   PMID:15195100   PMID:15314173   PMID:16791210   PMID:16854843   PMID:18560357   PMID:18697920   PMID:19946888   PMID:20458337   PMID:21804542  
PMID:22082260   PMID:22262176   PMID:22681889   PMID:23376485   PMID:23776465   PMID:23979707   PMID:24120868   PMID:24625528   PMID:24930395   PMID:25957688   PMID:27975169   PMID:29476059  
PMID:31904090   PMID:35352799  


Genomics

Comparative Map Data
Rpl11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85153,557,592 - 153,561,230 (-)NCBIGRCr8
mRatBN7.25148,274,060 - 148,277,708 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5148,274,069 - 148,277,599 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5150,973,410 - 150,976,617 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05152,747,677 - 152,750,884 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05152,729,697 - 152,732,904 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05154,390,809 - 154,394,412 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5154,388,140 - 154,394,328 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05158,155,377 - 158,158,967 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45154,826,973 - 154,830,183 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15154,837,011 - 154,840,222 (-)NCBI
Celera5146,679,072 - 146,682,282 (-)NCBICelera
Cytogenetic Map5q36NCBI
RPL11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38123,691,779 - 23,696,835 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl123,691,742 - 23,696,835 (+)EnsemblGRCh38hg38GRCh38
GRCh37124,018,269 - 24,023,325 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36123,890,881 - 23,895,502 (+)NCBINCBI36Build 36hg18NCBI36
Build 34123,763,599 - 23,768,221NCBI
Celera122,348,001 - 22,352,622 (+)NCBICelera
Cytogenetic Map1p36.11NCBI
HuRef122,268,974 - 22,273,620 (+)NCBIHuRef
CHM1_1124,130,853 - 24,135,499 (+)NCBICHM1_1
T2T-CHM13v2.0123,526,679 - 23,531,735 (+)NCBIT2T-CHM13v2.0
Rpl11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394135,776,665 - 135,780,704 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4135,755,576 - 135,780,739 (-)EnsemblGRCm39 Ensembl
GRCm384136,049,354 - 136,053,393 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4136,028,265 - 136,053,428 (-)EnsemblGRCm38mm10GRCm38
MGSCv374135,605,863 - 135,609,286 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364135,322,024 - 135,325,447 (-)NCBIMGSCv36mm8
Celera4134,251,682 - 134,255,104 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map468.34NCBI
Rpl11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554523,626,609 - 3,633,209 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554523,626,609 - 3,630,911 (+)NCBIChiLan1.0ChiLan1.0
RPL11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21203,244,964 - 203,249,854 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11202,347,916 - 202,359,894 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0122,883,157 - 22,887,806 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1123,868,700 - 23,873,313 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl123,868,688 - 23,873,313 (+)Ensemblpanpan1.1panPan2
RPL11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1275,781,210 - 75,785,614 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl275,781,091 - 75,785,605 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha272,351,349 - 72,355,753 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0276,340,583 - 76,344,987 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl276,289,729 - 76,344,987 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1273,162,911 - 73,167,314 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0274,169,764 - 74,174,173 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0275,175,305 - 75,179,710 (-)NCBIUU_Cfam_GSD_1.0
Rpl11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505843,031,000 - 43,033,505 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364748,855,782 - 8,858,287 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPL11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl681,522,742 - 81,530,436 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1681,523,510 - 81,526,925 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2675,499,944 - 75,503,353 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RPL11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120108,982,781 - 108,987,667 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20108,981,723 - 108,987,734 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660337,345,061 - 7,349,949 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rpl11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247648,258,709 - 8,266,016 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247648,258,656 - 8,262,842 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rpl11
37 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:99
Count of miRNA genes:84
Interacting mature miRNAs:93
Transcripts:ENSRNOT00000030043
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)5103689353148689353Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5105999803150999803Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5120740824151018848Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5143799107158428037Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5144377876161317411Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000030043   ⟹   ENSRNOP00000037110
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5148,274,294 - 148,277,599 (-)Ensembl
Rnor_6.0 Ensembl5154,390,848 - 154,394,328 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000079823   ⟹   ENSRNOP00000069811
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5148,274,069 - 148,277,274 (-)Ensembl
Rnor_6.0 Ensembl5154,390,816 - 154,394,023 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000090019   ⟹   ENSRNOP00000072829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5154,388,140 - 154,393,697 (-)Ensembl
RefSeq Acc Id: NM_001025739   ⟹   NP_001020910
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85153,557,592 - 153,560,802 (-)NCBI
mRatBN7.25148,274,064 - 148,277,274 (-)NCBI
Rnor_6.05154,390,813 - 154,394,023 (-)NCBI
Rnor_5.05158,155,377 - 158,158,967 (-)NCBI
RGSC_v3.45154,826,973 - 154,830,183 (-)RGD
Celera5146,679,072 - 146,682,282 (-)RGD
Sequence:
RefSeq Acc Id: XM_006239224   ⟹   XP_006239286
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85153,557,592 - 153,561,230 (-)NCBI
mRatBN7.25148,274,060 - 148,277,708 (-)NCBI
Rnor_6.05154,390,809 - 154,394,412 (-)NCBI
Rnor_5.05158,155,377 - 158,158,967 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039110410   ⟹   XP_038966338
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85153,557,592 - 153,560,940 (-)NCBI
mRatBN7.25148,274,060 - 148,277,399 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001020910   ⟸   NM_001025739
- UniProtKB: Q4V8I6 (UniProtKB/TrEMBL),   A0A0G2JWB2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239286   ⟸   XM_006239224
- Peptide Label: isoform X1
- UniProtKB: P62914 (UniProtKB/Swiss-Prot),   A6IT94 (UniProtKB/TrEMBL),   A0A0G2JWB2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000072829   ⟸   ENSRNOT00000090019
RefSeq Acc Id: ENSRNOP00000069811   ⟸   ENSRNOT00000079823
RefSeq Acc Id: ENSRNOP00000037110   ⟸   ENSRNOT00000030043
RefSeq Acc Id: XP_038966338   ⟸   XM_039110410
- Peptide Label: isoform X2
- UniProtKB: Q4V8I6 (UniProtKB/TrEMBL),   A0A0G2JWB2 (UniProtKB/TrEMBL)
Protein Domains
Large ribosomal subunit protein uL5 C-terminal   Large ribosomal subunit protein uL5 N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P62914-F1-model_v2 AlphaFold P62914 1-178 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694169
Promoter ID:EPDNEW_R4690
Type:multiple initiation site
Name:Rpl11_1
Description:ribosomal protein L11
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05154,394,348 - 154,394,408EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308681 AgrOrtholog
BioCyc Gene G2FUF-39518 BioCyc
Ensembl Genes ENSRNOG00000026260 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000030043.6 UniProtKB/TrEMBL
  ENSRNOT00000079823 ENTREZGENE
  ENSRNOT00000079823.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1440.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7444187 IMAGE-MGC_LOAD
InterPro Ribosomal_L5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_L5_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_L5_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_L5_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_L5_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:362631 UniProtKB/TrEMBL
MGC_CLONE MGC:114407 IMAGE-MGC_LOAD
NCBI Gene 362631 ENTREZGENE
PANTHER 60S RIBOSOMAL PROTEIN L11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11994 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ribosomal_L5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_L5_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rpl11 PhenoGen
PIRSF Ribosomal_L5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE RIBOSOMAL_L5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000026260 RatGTEx
Superfamily-SCOP SSF55282 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JWB2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QJB2_RAT UniProtKB/TrEMBL
  A6IT94 ENTREZGENE, UniProtKB/TrEMBL
  A6IT95_RAT UniProtKB/TrEMBL
  P62914 ENTREZGENE
  Q4V8I6 ENTREZGENE, UniProtKB/TrEMBL
  RL11_RAT UniProtKB/Swiss-Prot
UniProt Secondary P25121 UniProtKB/Swiss-Prot
  P39026 UniProtKB/Swiss-Prot
  Q9Y674 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Rpl11  ribosomal protein L11  Rpl11_predicted  ribosomal protein L11 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Rpl11_predicted  ribosomal protein L11 (predicted)      Symbol and Name status set to approved 70820 APPROVED