Gene: Pklr (pyruvate kinase, liver and RBC) Rattus norvegicus
Symbol: Pklr
Name: pyruvate kinase, liver and RBC
Description: ENCODES a protein that exhibits pyruvate kinase activity; INVOLVED IN ATP biosynthetic process; carbohydrate metabolic process; cellular response to insulin stimulus; PARTICIPATES IN glycolysis pathway; pyruvate metabolic pathway; forkhead class A signaling pathway; ASSOCIATED WITH Burns; Diabetes Mellitus, Experimental; Hyperglycemia; FOUND IN cytosol; extracellular vesicular exosome (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,2',5,5'-tetrachlorobiphenyl
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: L-PK; PK1; PKL; Pklg; pyruvate kinase isozymes L/R; pyruvate kinase isozymes R/L; pyruvate kinase PKLR; pyruvate kinase, liver and red blood cell
Orthologs:
Is Marker For: Strains:   WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc   WKY.SHRSP-(Fst-Pklr)/Gcrc  
QTLs:   Niddm8  
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map2q34 NCBI
RGSC Genome Assembly v5.02207,865,529 - 207,874,394+NCBI
RGSC Genome Assembly v3.42181,214,853 - 181,223,505+NCBI
Rat Celera Assembly2168,486,468 - 168,494,841+NCBI
Genome Assembly 3.12181,164,961 - 181,173,618+NCBI
RH 3.421154.4 RGD
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pklr
Entrez Gene
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RGD Object Information
RGD ID: 3336
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2014-08-12
Status: ACTIVE