Gene: Pklr (pyruvate kinase L/R) Rattus norvegicus
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Symbol: Pklr
Name: pyruvate kinase L/R
Description: ENCODES a protein that exhibits pyruvate kinase activity; INVOLVED IN ATP biosynthetic process; carbohydrate metabolic process; cellular response to epinephrine stimulus; PARTICIPATES IN glycolysis pathway; pyruvate metabolic pathway; fanconi syndrome pathway; ASSOCIATED WITH Burns; Diabetes Mellitus, Experimental; Hyperglycemia; FOUND IN cytosol; extracellular exosome (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: L-PK; PK1; PKL; Pklg; pyruvate kinase isozymes L/R; pyruvate kinase isozymes R/L; pyruvate kinase PKLR; pyruvate kinase, liver and RBC; pyruvate kinase, liver and red blood cell
Orthologs:
Homo sapiens (human) : PKLR (pyruvate kinase L/R)  HGNC  AGR
Mus musculus (house mouse) : Pklr (pyruvate kinase liver and red blood cell)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Pklr (pyruvate kinase L/R)
Pan paniscus (bonobo/pygmy chimpanzee) : PKLR (pyruvate kinase L/R)
Canis lupus familiaris (dog) : PKLR (pyruvate kinase L/R)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pklr (pyruvate kinase L/R)
more info ...
Is Marker For: Strains:   WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc   WKY.SHRSP-(Fst-Pklr)/Gcrc  
QTLs:   Niddm8  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02188,449,158 - 188,458,034 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02207,865,529 - 207,874,394 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42181,214,853 - 181,223,505 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12181,164,961 - 181,173,618 (+)NCBI
Celera2168,486,468 - 168,494,841 (+)NCBICelera
Cytogenetic Map2q34NCBI
RH 3.4 Map21154.4RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
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miRNA Target Status

Sequence

Nucleotide Sequences
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Strain Variation

Strain Sequence Variants

Additional Information

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Nomenclature History
RGD Curation Notes
 
More on Pklr
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3336
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-10-24
Status: ACTIVE