Gene: Pklr (pyruvate kinase, liver and RBC) Rattus norvegicus
Symbol: Pklr
Name: pyruvate kinase, liver and RBC
Description: ENCODES a protein that exhibits pyruvate kinase activity; INVOLVED IN ATP biosynthetic process; carbohydrate metabolic process; cellular response to insulin stimulus; PARTICIPATES IN glycolysis pathway; pyruvate metabolic pathway; forkhead class A signaling pathway; ASSOCIATED WITH Burns; Diabetes Mellitus, Experimental; Hyperglycemia; FOUND IN cytosol; extracellular exosome (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,2',5,5'-tetrachlorobiphenyl
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: L-PK; PK1; PKL; Pklg; pyruvate kinase isozymes L/R; pyruvate kinase isozymes R/L; pyruvate kinase PKLR; pyruvate kinase, liver and red blood cell
Is Marker For: Strains:   WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc   WKY.SHRSP-(Fst-Pklr)/Gcrc  
QTLs:   Niddm8  
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.02188,449,157 - 188,458,034+NCBI
Rat Cytogenetic Map2q34 NCBI
RGSC Genome Assembly v5.02207,865,529 - 207,874,394+NCBI
RGSC Genome Assembly v3.42181,214,853 - 181,223,505+NCBI
Rat Celera Assembly2168,486,468 - 168,494,841+NCBI
Genome Assembly 3.12181,164,961 - 181,173,618+NCBI
RH 3.421154.4 RGD

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Nucleotide Sequences
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Strain Sequence Variants

Additional Information

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Nomenclature History
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RGD Object Information
RGD ID: 3336
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2015-08-11
Status: ACTIVE