Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-alpha-phellandrene | increases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | alpha phellandrene results in increased expression of SLC44A3 mRNA | CTD | PMID:25075043 | (1->4)-beta-D-glucan | multiple interactions | ISO | Slc44a3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SLC44A3 mRNA | CTD | PMID:36331819 | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of SLC44A3 mRNA | CTD | PMID:30723492 | 17beta-estradiol | multiple interactions | ISO | SLC44A3 (Homo sapiens) | 6480464 | [Estradiol co-treated with Progesterone] results in increased expression of SLC44A3 mRNA and [Estradiol co-treated with TGFB1 protein] results in decreased expression of SLC44A3 mRNA | CTD | PMID:20660070 and PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SLC44A3 mRNA | CTD | PMID:20106945 and PMID:21632981 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SLC44A3 mRNA | CTD | PMID:33387578 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of SLC44A3 mRNA | CTD | PMID:24780913 and PMID:30047161 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of SLC44A3 mRNA | CTD | PMID:31881176 | aflatoxin B1 | decreases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of SLC44A3 mRNA | CTD | PMID:27153756 | all-trans-retinoic acid | increases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of SLC44A3 mRNA | CTD | PMID:21934132 | all-trans-retinoic acid | increases expression | ISO | Slc44a3 (Mus musculus) | 6480464 | Tretinoin results in increased expression of SLC44A3 mRNA | CTD | PMID:36189433 | all-trans-retinoic acid | multiple interactions | ISO | Slc44a3 (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLC44A3 mRNA | CTD | PMID:36189433 | all-trans-retinoic acid | decreases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of SLC44A3 mRNA | CTD | PMID:23724009 | alpha-phellandrene | increases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | alpha phellandrene results in increased expression of SLC44A3 mRNA | CTD | PMID:25075043 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of SLC44A3 mRNA | CTD | PMID:30047161 | azathioprine | decreases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | Azathioprine results in decreased expression of SLC44A3 mRNA | CTD | PMID:22623647 | belinostat | decreases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | belinostat results in decreased expression of SLC44A3 mRNA | CTD | PMID:27188386 | benzo[a]pyrene | decreases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of SLC44A3 mRNA | CTD | PMID:21632981 | benzo[a]pyrene | affects methylation | ISO | SLC44A3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of SLC44A3 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | SLC44A3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of SLC44A3 5' UTR | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | increases expression | ISO | Slc44a3 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of SLC44A3 mRNA | CTD | PMID:19850644 | bis(2-ethylhexyl) phthalate | increases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of SLC44A3 mRNA | CTD | PMID:31163220 | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | Slc44a3 (Mus musculus) | 6480464 | PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of SLC44A3 mRNA] | CTD | PMID:19850644 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SLC44A3 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | Slc44a3 (Mus musculus) | 6480464 | bisphenol A results in increased expression of SLC44A3 mRNA | CTD | PMID:34585602 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SLC44A3 mRNA | CTD | PMID:32145629 | bisphenol A | increases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of SLC44A3 mRNA | CTD | PMID:31715268 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of SLC44A3 gene | CTD | PMID:28505145 | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of SLC44A3 mRNA | CTD | PMID:32479839 | carbon nanotube | decreases expression | ISO | Slc44a3 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25620056 | choline | multiple interactions | ISO | Slc44a3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of SLC44A3 gene | CTD | PMID:20938992 | copper(II) sulfate | decreases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of SLC44A3 mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of SLC44A3 mRNA | CTD | PMID:20106945 more ... | dextran sulfate | multiple interactions | ISO | Slc44a3 (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC44A3 mRNA | CTD | PMID:29950665 | dicrotophos | decreases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of SLC44A3 mRNA | CTD | PMID:28302478 | dioxygen | multiple interactions | ISO | Slc44a3 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of SLC44A3 mRNA | CTD | PMID:30529165 | dorsomorphin | multiple interactions | ISO | SLC44A3 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of SLC44A3 mRNA | CTD | PMID:29391264 | entinostat | increases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | entinostat results in increased expression of SLC44A3 mRNA | CTD | PMID:26272509 and PMID:27188386 | entinostat | multiple interactions | ISO | SLC44A3 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC44A3 mRNA | CTD | PMID:27188386 | epoxiconazole | decreases expression | ISO | Slc44a3 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of SLC44A3 mRNA | CTD | PMID:35436446 | fenthion | increases expression | ISO | Slc44a3 (Mus musculus) | 6480464 | Fenthion results in increased expression of SLC44A3 mRNA | CTD | PMID:34813904 | folic acid | multiple interactions | ISO | Slc44a3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of SLC44A3 gene | CTD | PMID:20938992 | FR900359 | increases phosphorylation | ISO | SLC44A3 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of SLC44A3 protein | CTD | PMID:37730182 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of SLC44A3 mRNA | CTD | PMID:25539665 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of SLC44A3 mRNA | CTD | PMID:33387578 | glyphosate | decreases methylation | EXP | | 6480464 | Glyphosate results in decreased methylation of SLC44A3 gene | CTD | PMID:31011160 | glyphosate | affects methylation | EXP | | 6480464 | Glyphosate affects the methylation of SLC44A3 gene | CTD | PMID:35440735 | L-methionine | multiple interactions | ISO | Slc44a3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of SLC44A3 gene | CTD | PMID:20938992 | lipopolysaccharide | multiple interactions | ISO | SLC44A3 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of SLC44A3 mRNA | CTD | PMID:35811015 | mercury dibromide | increases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | mercuric bromide results in increased expression of SLC44A3 mRNA | CTD | PMID:26272509 | mercury dibromide | multiple interactions | ISO | SLC44A3 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC44A3 mRNA | CTD | PMID:27188386 | methidathion | increases expression | ISO | Slc44a3 (Mus musculus) | 6480464 | methidathion results in increased expression of SLC44A3 mRNA | CTD | PMID:34813904 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of SLC44A3 mRNA | CTD | PMID:30047161 | mono(2-ethylhexyl) phthalate | multiple interactions | ISO | Slc44a3 (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLC44A3 mRNA | CTD | PMID:36189433 | Monobutylphthalate | increases expression | EXP | | 6480464 | monobutyl phthalate results in increased expression of SLC44A3 mRNA | CTD | PMID:29162477 | paracetamol | decreases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of SLC44A3 mRNA | CTD | PMID:29067470 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of SLC44A3 mRNA | CTD | PMID:33387578 | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of SLC44A3 mRNA | CTD | PMID:32680482 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Slc44a3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SLC44A3 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of SLC44A3 mRNA | CTD | PMID:36331819 | phenylmercury acetate | increases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of SLC44A3 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | SLC44A3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC44A3 mRNA | CTD | PMID:27188386 | pirinixic acid | increases expression | ISO | Slc44a3 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of SLC44A3 mRNA | CTD | PMID:18301758 and PMID:23811191 | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Slc44a3 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of SLC44A3 mRNA | CTD | PMID:27413110 and PMID:28903501 | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of SLC44A3 mRNA | CTD | PMID:30047161 | progesterone | decreases expression | ISO | Slc44a3 (Mus musculus) | 6480464 | Progesterone results in decreased expression of SLC44A3 mRNA | CTD | PMID:17556502 | progesterone | multiple interactions | ISO | SLC44A3 (Homo sapiens) | 6480464 | [Estradiol co-treated with Progesterone] results in increased expression of SLC44A3 mRNA | CTD | PMID:20660070 | progesterone | multiple interactions | ISO | Slc44a3 (Mus musculus) | 6480464 | NCOA2 protein affects the reaction [Progesterone results in decreased expression of SLC44A3 mRNA] | CTD | PMID:17556502 | quercetin | decreases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of SLC44A3 mRNA | CTD | PMID:21632981 | S-(1,2-dichlorovinyl)-L-cysteine | increases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | S-(1 and 2-dichlorovinyl)cysteine results in increased expression of SLC44A3 mRNA | CTD | PMID:35811015 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | SLC44A3 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of SLC44A3 mRNA | CTD | PMID:35811015 | SB 431542 | multiple interactions | ISO | SLC44A3 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of SLC44A3 mRNA | CTD | PMID:25895662 | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of SLC44A3 mRNA | CTD | PMID:30047161 | tetrachloromethane | increases expression | ISO | Slc44a3 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of SLC44A3 mRNA | CTD | PMID:31919559 | thalidomide | decreases expression | ISO | Slc44a3 (Mus musculus) | 6480464 | Thalidomide results in decreased expression of SLC44A3 mRNA | CTD | PMID:26217789 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of SLC44A3 mRNA | CTD | PMID:34492290 | titanium dioxide | multiple interactions | ISO | Slc44a3 (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC44A3 mRNA | CTD | PMID:29950665 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of SLC44A3 mRNA | CTD | PMID:33387578 | triclosan | increases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | Triclosan results in increased expression of SLC44A3 mRNA | CTD | PMID:30510588 | valproic acid | affects expression | ISO | Slc44a3 (Mus musculus) | 6480464 | Valproic Acid affects the expression of SLC44A3 mRNA | CTD | PMID:17292431 | valproic acid | multiple interactions | ISO | SLC44A3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC44A3 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SLC44A3 mRNA | CTD | PMID:23179753 more ... | valproic acid | decreases expression | ISO | SLC44A3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of SLC44A3 mRNA | CTD | PMID:29154799 | vancomycin | decreases expression | ISO | Slc44a3 (Mus musculus) | 6480464 | Vancomycin results in decreased expression of SLC44A3 mRNA | CTD | PMID:18930951 | |