Gene: Scnn1a (sodium channel, non-voltage-gated 1 alpha subunit) Rattus norvegicus
Symbol: Scnn1a
Name: sodium channel, non-voltage-gated 1 alpha subunit
Description: ENCODES a protein that exhibits actin binding; ligand-gated sodium channel activity; WW domain binding; INVOLVED IN regulation of body fluid levels; sodium ion transport; multicellular organismal water homeostasis (ortholog); PARTICIPATES IN aldosterone signaling pathway; ASSOCIATED WITH Nephrotic Syndrome; Bronchiectasis With Or Without Elevated Sweat Chloride 2 (ortholog); Neuroblastoma (ortholog); FOUND IN apical plasma membrane; cortical actin cytoskeleton; ciliary membrane (ortholog); INTERACTS WITH 2,4,6-trinitrotoluene; 2,4-dinitrotoluene; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: alpha-ENaC; alpha-NaCH; amiloride-sensitive sodium channel subunit alpha; epithelial Na(+) channel subunit alpha; epithelial sodium channel alpha subunit; nonvoltage-gated sodium channel 1 subunit alpha; SCNEA; Sodium channel nonvoltage-gated 1 alpha (epithelial); sodium channel, nonvoltage-gated 1 alpha; sodium channel, nonvoltage-gated, type 1, alpha subunit; sodium channel, nonvoltage-gated, type I, alpha; sodium channel, nonvoltage-gated, type I, alpha polypeptide
Orthologs:
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
RGSC Genome Assembly v6.04157,835,474 - 157,860,513+NCBI
Rat Cytogenetic Map4q42 NCBI
RGSC Genome Assembly v5.04224,853,710 - 224,877,459+NCBI
RGSC Genome Assembly v3.44161,445,936 - 161,469,267+NCBI
Rat Celera Assembly4146,859,208 - 146,882,414+NCBI
Genome Assembly 3.14161,690,871 - 161,714,200+NCBI
RH 3.441000.7 RGD
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Scnn1a
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RGD Object Information
RGD ID: 3639
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2014-09-10
Status: ACTIVE