Gene: Scnn1a (sodium channel epithelial 1 alpha subunit) Rattus norvegicus
Symbol: Scnn1a
Name: sodium channel epithelial 1 alpha subunit
Description: ENCODES a protein that exhibits actin binding; ligand-gated sodium channel activity; WW domain binding; INVOLVED IN regulation of body fluid levels; sodium ion transport; multicellular organismal water homeostasis (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH Nephrotic Syndrome; Bronchiectasis with or without Elevated Sweat Chloride 2 (ortholog); Neuroblastoma (ortholog); FOUND IN apical plasma membrane; cortical actin cytoskeleton; ciliary membrane (ortholog); INTERACTS WITH 2,4,6-trinitrotoluene; 2,4-dinitrotoluene; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: alpha-ENaC; alpha-NaCH; amiloride-sensitive sodium channel subunit alpha; epithelial Na(+) channel subunit alpha; epithelial sodium channel alpha subunit; nonvoltage-gated sodium channel 1 subunit alpha; SCNEA; Sodium channel nonvoltage-gated 1 alpha (epithelial); sodium channel, non-voltage-gated 1 alpha subunit; sodium channel, nonvoltage-gated 1 alpha; sodium channel, nonvoltage-gated, type 1, alpha subunit; sodium channel, nonvoltage-gated, type I, alpha; sodium channel, nonvoltage-gated, type I, alpha polypeptide
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04157,835,474 - 157,860,513 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.04224,853,710 - 224,877,459 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.44161,445,936 - 161,469,267 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14161,690,871 - 161,714,200 (+)NCBI
Celera4146,859,208 - 146,882,414 (+)NCBI
Cytogenetic Map4q42NCBImapview
RH 3.4 Map41000.7RGD
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Scnn1a
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 3639
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-05-10
Status: ACTIVE