Gene: Scnn1a (sodium channel, non-voltage-gated 1 alpha subunit) Rattus norvegicus
Symbol: Scnn1a
Name: sodium channel, non-voltage-gated 1 alpha subunit
Description: ENCODES a protein that exhibits actin binding; ligand-gated sodium channel activity; WW domain binding; INVOLVED IN regulation of body fluid levels; sodium ion transport; multicellular organismal water homeostasis (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH Nephrotic Syndrome; Bronchiectasis with or without Elevated Sweat Chloride 2 (ortholog); Neuroblastoma (ortholog); FOUND IN apical plasma membrane; cortical actin cytoskeleton; ciliary membrane (ortholog); INTERACTS WITH 2,4,6-trinitrotoluene; 2,4-dinitrotoluene; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine
Type: protein-coding
Also known as: alpha-ENaC; alpha-NaCH; amiloride-sensitive sodium channel subunit alpha; epithelial Na(+) channel subunit alpha; epithelial sodium channel alpha subunit; nonvoltage-gated sodium channel 1 subunit alpha; SCNEA; Sodium channel nonvoltage-gated 1 alpha (epithelial); sodium channel, nonvoltage-gated 1 alpha; sodium channel, nonvoltage-gated, type 1, alpha subunit; sodium channel, nonvoltage-gated, type I, alpha; sodium channel, nonvoltage-gated, type I, alpha polypeptide
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.04157,835,474 - 157,860,513+NCBI
Rat Cytogenetic Map4q42 NCBI
RGSC Genome Assembly v5.04224,853,710 - 224,877,459+NCBI
RGSC Genome Assembly v3.44161,445,936 - 161,469,267+NCBI
Rat Celera Assembly4146,859,208 - 146,882,414+NCBI
Genome Assembly 3.14161,690,871 - 161,714,200+NCBI
RH 3.441000.7 RGD

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Nucleotide Sequences
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Nomenclature History
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RGD Object Information
RGD ID: 3639
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-02-02
Status: ACTIVE