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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cytokine production involved in immune response
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Accession:GO:0002718 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response.
Synonyms:narrow_synonym: regulation of cytokine biosynthetic process involved in immune response;   regulation of cytokine secretion involved in immune response
 related_synonym: regulation of cytokine production during immune response
 alt_id: GO:0002739;   GO:0002742



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regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg5 autophagy related 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:22710871)
Ensembl
RGD
PMID:22710871 GO_REF:0000107 NCBI chr20:49,380,835...49,471,826
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Pkp3 plakophilin 3 involved_in ISO (PMID:26173741) RGD PMID:26173741 NCBI chr 1:196,187,914...196,198,843
Ensembl chr 1:196,187,835...196,198,844
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO UniProtKB:Q9Z0D9 (PMID:28052249) RGD PMID:28052249 NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:157,070,642...157,104,206
JBrowse link
G Tril TLR4 interactor with leucine-rich repeats involved_in ISO
IBA
(PMID:19710467)
GO_REF:0000033
RGD
GO_Central
PMID:19710467 GO_REF:0000033 NCBI chr 4:84,252,781...84,257,626
Ensembl chr 4:82,922,328...82,927,172
JBrowse link
negative regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:20060382)
Ensembl
RGD
PMID:20060382 GO_REF:0000107 NCBI chr 7:75,415,959...75,668,696
Ensembl chr 7:73,531,486...73,784,067
JBrowse link
G Apoa1 apolipoprotein A1 involved_in ISO
IEA
(PMID:12458630)
GO_REF:0000107
RGD
Ensembl
PMID:12458630 GO_REF:0000107 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:12458630) RGD PMID:12458630 NCBI chr13:86,176,767...86,178,819
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Il10 interleukin 10 involved_in ISS
ISO
GO_REF:0000024
(PMID:10443688)
UniProt
RGD
PMID:10443688 GO_REF:0000024 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:10443688) RGD PMID:10443688 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
JBrowse link
negative regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jak3 Janus kinase 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:16020505)
BHF-UCL
RGD
PMID:16020505 GO_REF:0000024 NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,386,405...18,398,536
JBrowse link
negative regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2180086 (PMID:11168643)
Ensembl
RGD
PMID:11168643 GO_REF:0000107 NCBI chr 8:28,939,984...28,946,639
Ensembl chr 8:20,663,985...20,667,929
JBrowse link
G Atg9a autophagy related 9A acts_upstream_of_or_within ISO (PMID:24670807) RGD PMID:24670807 NCBI chr 9:84,126,071...84,136,723
Ensembl chr 9:76,677,404...76,687,986
JBrowse link
G Axl Axl receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:107670 (PMID:16831897) RGD PMID:16831897 NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G Cuedc2 CUE domain containing 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:24882011)
MGI:5635142 (PMID:24882011)
GO_REF:0000107
RGD
Ensembl
PMID:24882011 GO_REF:0000107 NCBI chr 1:245,192,057...245,200,594
Ensembl chr 1:245,192,063...245,200,339
JBrowse link
G Epx eosinophil peroxidase acts_upstream_of_or_within ISO MGI:2182952 (PMID:16926417) RGD PMID:16926417 NCBI chr10:73,164,096...73,175,180
Ensembl chr10:72,666,865...72,677,952
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in ISO (PMID:12150927) RGD PMID:12150927 NCBI chr 7:57,538,522...57,600,166
Ensembl chr 7:55,653,962...55,713,121
JBrowse link
G Nlrx1 NLR family member X1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:5141085 (PMID:21703540)
Ensembl
RGD
PMID:21703540 GO_REF:0000107 NCBI chr 8:53,486,866...53,503,498
Ensembl chr 8:44,590,048...44,606,484
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:2680581 (PMID:15220916) RGD PMID:15220916 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G Prg2 proteoglycan 2, pro eosinophil major basic protein involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3027719 (PMID:16926417)
Ensembl
RGD
PMID:16926417 GO_REF:0000107 NCBI chr 3:90,469,192...90,472,759
Ensembl chr 3:70,062,535...70,066,101
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS
(PMID:20875417)
GO_REF:0000024
RGD
AgBase
PMID:20875417 GO_REF:0000024 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:20875417)
AgBase
RGD
PMID:20875417 GO_REF:0000024 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISO
ISS
(PMID:20875417)
GO_REF:0000024
RGD
AgBase
PMID:20875417 GO_REF:0000024 NCBI chr 6:111,435,170...111,457,646
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Twist1 twist family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:104685 (PMID:16831897) RGD PMID:16831897 NCBI chr 6:56,402,309...56,404,303
Ensembl chr 6:50,674,678...50,677,653
JBrowse link
G Twist2 twist family bHLH transcription factor 2 acts_upstream_of_or_within ISO MGI:3044412|MGI:98872 (PMID:16831897) RGD PMID:16831897 NCBI chr 9:92,374,740...92,419,222
Ensembl chr 9:92,374,574...92,419,222
JBrowse link
negative regulation of mast cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:2158436 (PMID:15950739) RGD PMID:15950739 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:17234154 RGD:1601626 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO MGI:3051384 (PMID:16533754) RGD PMID:16533754 NCBI chr12:26,459,190...26,503,790
Ensembl chr12:26,460,175...26,503,744
JBrowse link
negative regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd96 CD96 molecule acts_upstream_of_or_within ISO MGI:5617136 (PMID:24658051) RGD PMID:24658051 NCBI chr11:68,164,926...68,239,266
Ensembl chr11:54,702,290...54,776,621
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,407,880...3,484,130 JBrowse link
negative regulation of plasmacytoid dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bst2 bone marrow stromal cell antigen 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:19564354)
UniProt
RGD
PMID:19564354 GO_REF:0000024 NCBI chr16:18,250,593...18,254,967
Ensembl chr16:18,217,407...18,220,979
JBrowse link
negative regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 involved_in ISO (PMID:15466453), (PMID:23169781) RGD PMID:15466453 PMID:23169781 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Hfe homeostatic iron regulator involved_in ISO UniProtKB:P04439 (PMID:24643698) RGD PMID:24643698 NCBI chr17:41,841,302...41,849,359
Ensembl chr17:41,413,451...41,421,502
JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:18420485) RGD PMID:18420485 NCBI chr 1:78,847,685...78,853,294
Ensembl chr 1:69,805,250...69,810,660
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,407,880...3,484,130 JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (PMID:11477403) RGD PMID:11477403 NCBI chr13:86,802,708...86,837,890
Ensembl chr13:84,270,316...84,305,497
JBrowse link
G Smad7 SMAD family member 7 involved_in IEA
ISO
GO_REF:0000107
(PMID:25642768)
Ensembl
RGD
PMID:25642768 GO_REF:0000107 NCBI chr18:71,263,508...71,291,849
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Vsir V-set immunoregulatory receptor acts_upstream_of_or_within ISO (PMID:21383057) RGD PMID:21383057 NCBI chr20:28,824,493...28,850,175
Ensembl chr20:28,281,596...28,303,878
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:10887101) RGD PMID:10887101 NCBI chr13:79,781,784...79,785,440
Ensembl chr13:77,248,717...77,252,329
JBrowse link
negative regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:19360123)
Ensembl
RGD
PMID:19360123 GO_REF:0000107 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (PMID:20554961) RGD PMID:20554961 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (PMID:10761931), (PMID:23616576) RGD PMID:10761931 PMID:23616576 NCBI chr10:82,578,751...82,595,253
Ensembl chr10:82,082,322...82,098,831
JBrowse link
positive regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec7a C-type lectin domain containing 7A involved_in IBA
ISO
GO_REF:0000033
(PMID:27288407)
GO_Central
RGD
PMID:27288407 GO_REF:0000033 NCBI chr 4:164,588,737...164,599,953
Ensembl chr 4:162,902,732...162,913,897
JBrowse link
G Defb43 defensin beta 43 involved_in ISO (PMID:26649771) RGD PMID:26649771 NCBI chr15:41,447,875...41,452,769
Ensembl chr15:37,272,008...37,276,626
JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:11441110)
UniProt
RGD
PMID:11441110 GO_REF:0000024 NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G Ffar2 free fatty acid receptor 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:23665276)
UniProt
RGD
PMID:23665276 GO_REF:0000024 NCBI chr 1:95,199,277...95,202,599
Ensembl chr 1:86,072,184...86,075,033
JBrowse link
G Ffar3 free fatty acid receptor 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:23665276)
UniProt
RGD
PMID:23665276 GO_REF:0000024 NCBI chr 1:95,232,804...95,234,144
Ensembl chr 1:86,104,920...86,106,849
JBrowse link
G Hk1 hexokinase 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:27374331)
Ensembl
RGD
PMID:27374331 GO_REF:0000107 NCBI chr20:30,773,222...30,874,814
Ensembl chr20:30,230,486...30,332,131
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IMP RGD PMID:19318092 RGD:401901206 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Inava innate immunity activator involved_in ISO (PMID:28436939) RGD PMID:28436939 NCBI chr13:50,218,149...50,238,430
Ensembl chr13:47,666,447...47,686,729
JBrowse link
G Irf5 interferon regulatory factor 5 involved_in ISO (PMID:29046356) RGD PMID:29046356 NCBI chr 4:59,092,914...59,104,596
Ensembl chr 4:58,127,640...58,139,267
JBrowse link
G Lacc1 laccase domain containing 1 involved_in ISO (PMID:28593945) RGD PMID:28593945 NCBI chr15:58,799,477...58,816,840
Ensembl chr15:52,395,183...52,407,545
JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:22733818) RGD PMID:22733818 NCBI chr 5:148,371,880...148,393,927
Ensembl chr 5:143,087,759...143,109,807
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in ISO (PMID:27374331) RGD PMID:27374331 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO (PMID:16260731) RGD PMID:16260731 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:27288407) RGD PMID:27288407 NCBI chr10:56,006,243...56,026,357
Ensembl chr10:55,507,519...55,528,171
JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (PMID:17346996) RGD PMID:17346996 NCBI chr 1:105,317,332...105,324,985
Ensembl chr 1:96,180,887...96,188,391
JBrowse link
G Tek TEK receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:20060382) RGD PMID:20060382 NCBI chr 5:114,722,815...114,849,535
Ensembl chr 5:109,607,077...109,733,804
JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:4940320 (PMID:21236258)
GO_Central
RGD
PMID:21236258 GO_REF:0000033 NCBI chr 5:170,768,413...170,776,749
Ensembl chr 5:165,484,262...165,493,703
JBrowse link
G Trim6 tripartite motif containing 6 involved_in ISO (PMID:24882218) RGD PMID:24882218 NCBI chr 1:168,095,619...168,108,809
Ensembl chr 1:158,683,746...158,696,914
JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:18174455) RGD PMID:18174455 NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,697,032...3,718,234
JBrowse link
positive regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec7a C-type lectin domain containing 7A involved_in ISO (PMID:19136564), (PMID:27288407) RGD PMID:19136564 PMID:27288407 NCBI chr 4:164,588,737...164,599,953
Ensembl chr 4:162,902,732...162,913,897
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO (PMID:18454155) RGD PMID:18454155 NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 IDA RGD PMID:16818757 RGD:1600784 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:19136564)
Ensembl
RGD
PMID:19136564 GO_REF:0000107 NCBI chr19:62,456,196...62,592,684
Ensembl chr19:45,547,416...45,683,930
JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:27288407) RGD PMID:27288407 NCBI chr10:56,006,243...56,026,357
Ensembl chr10:55,507,519...55,528,171
JBrowse link
positive regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card9 caspase recruitment domain family, member 9 acts_upstream_of_or_within ISO MGI:3698412 (PMID:17187069) RGD PMID:17187069 NCBI chr 3:29,569,907...29,578,402
Ensembl chr 3:9,171,815...9,180,237
JBrowse link
G Casp1 caspase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:18490713)
Ensembl
RGD
PMID:18490713 GO_REF:0000107 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp4 caspase 4 acts_upstream_of_or_within ISO MGI:1931465|MGI:2653833 (PMID:22002608) RGD PMID:22002608 NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Cd36 CD36 molecule involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2447190|MGI:3573941 (PMID:15690042), (PMID:16061696)
Ensembl
RGD
PMID:15690042 PMID:16061696 GO_REF:0000107 NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cd74 CD74 molecule involved_in ISS
ISO
IBA
GO_REF:0000024
(PMID:19413900)
GO_REF:0000033
BHF-UCL
RGD
GO_Central
PMID:19413900 GO_REF:0000024 GO_REF:0000033 NCBI chr18:56,527,071...56,536,406
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Gprc5b G protein-coupled receptor, class C, group 5, member B involved_in ISO (PMID:23169819) RGD PMID:23169819 NCBI chr 1:182,748,247...182,772,711
Ensembl chr 1:173,316,907...173,340,932
JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:9348310) RGD PMID:9348310 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:22733818) RGD PMID:22733818 NCBI chr 5:148,371,880...148,393,927
Ensembl chr 5:143,087,759...143,109,807
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 acts_upstream_of_or_within ISO (PMID:24020373) RGD PMID:24020373 NCBI chr13:45,066,027...45,112,326
Ensembl chr13:42,513,762...42,560,457
JBrowse link
G Mir324 microRNA 324 acts_upstream_of_or_within ISO (PMID:24882011) RGD PMID:24882011 NCBI chr10:54,734,680...54,734,762
Ensembl chr10:54,734,678...54,734,766
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of_or_within ISO MGI:2147032|MGI:2385681 (PMID:10607756), (PMID:11067888), (PMID:12872135) RGD PMID:10607756 PMID:11067888 PMID:12872135 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of_or_within ISO MGI:2429397|MGI:2674231 (PMID:18261938) RGD PMID:18261938 NCBI chr 4:85,391,142...85,442,281
Ensembl chr 4:84,060,880...84,111,404
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:1341839|MGI:2680581|MGI:3529594 (PMID:14560001), (PMID:15220916), (PMID:15692051), (PMID:18261938) RGD PMID:14560001 PMID:15220916 PMID:15692051 PMID:18261938 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:2386080|MGI:3606250 (PMID:11016935), (PMID:18490713) RGD PMID:11016935 PMID:18490713 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Panx1 Pannexin 1 acts_upstream_of_or_within ISO (PMID:18490713) RGD PMID:18490713 NCBI chr 8:20,128,783...20,171,200
Ensembl chr 8:11,850,730...11,889,774
JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
(PMID:22041900)
Ensembl
RGD
PMID:22041900 GO_REF:0000107 NCBI chr19:62,456,196...62,592,684
Ensembl chr19:45,547,416...45,683,930
JBrowse link
G Pycard PYD and CARD domain containing acts_upstream_of_or_within ISO MGI:107700|MGI:2653833 (PMID:22002608) RGD PMID:22002608 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO MGI:2660793 (PMID:11894098), (PMID:18261938) RGD PMID:11894098 PMID:18261938 NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:29,631,570...29,662,657
JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:19304799) RGD PMID:19304799 NCBI chr20:1,329,227...1,333,394
Ensembl chr20:1,287,521...1,328,117
JBrowse link
G Rtn4 reticulon 4 involved_in ISS
ISO
GO_REF:0000024
(PMID:19805174)
UniProt
RGD
PMID:19805174 GO_REF:0000024 NCBI chr14:107,651,001...107,698,610
Ensembl chr14:103,449,930...103,497,686
JBrowse link
G Sema7a semaphorin 7A (John Milton Hagen blood group) involved_in ISO (PMID:17377534) RGD PMID:17377534 NCBI chr 8:67,244,318...67,267,060
Ensembl chr 8:58,348,448...58,370,536
JBrowse link
G Sirt1 sirtuin 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:22315447)
Ensembl
RGD
PMID:22315447 GO_REF:0000107 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Spon2 spondin 2 acts_upstream_of_or_within ISO MGI:3026870 (PMID:14691481) RGD PMID:14691481 NCBI chr14:81,713,070...81,742,510
Ensembl chr14:77,511,901...77,517,996
JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO MGI:108005|MGI:2679794|MGI:3029019 (PMID:12855817), (PMID:12872135) RGD PMID:12855817 PMID:12872135 NCBI chr 9:1,189,717...1,197,730
Ensembl chr 9:1,102,366...1,123,147
JBrowse link
G Tirap TIR domain containing adaptor protein acts_upstream_of_or_within ISO MGI:3573942 (PMID:15690042) RGD PMID:15690042 NCBI chr 8:41,789,557...41,805,903
Ensembl chr 8:33,531,725...33,547,432
JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO MGI:2178675|MGI:2674036 (PMID:10549626), (PMID:11067888), (PMID:15690042), (PMID:18261938) RGD PMID:10549626 PMID:11067888 PMID:15690042 PMID:18261938 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tlr3 toll-like receptor 3 acts_upstream_of_or_within ISO MGI:3690535 (PMID:12855817), (PMID:18261938) RGD PMID:12855817 PMID:18261938 NCBI chr16:53,554,916...53,572,321
Ensembl chr16:46,822,039...46,836,545
JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857718|MGI:1860755|MGI:1860885 (PMID:10549626), (PMID:10607756), (PMID:10623794), (PMID:14691481), (PMID:15661922), (PMID:18261938), (PMID:21609717)
Ensembl
RGD
PMID:10549626 PMID:10607756 PMID:10623794 PMID:14691481 PMID:15661922 More... GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr7 toll-like receptor 7 acts_upstream_of_or_within ISO (PMID:18261938) RGD PMID:18261938 NCBI chr  X:30,644,324...30,670,796
Ensembl chr  X:27,027,425...27,054,754
JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO
IEA
(PMID:18174455)
GO_REF:0000107
RGD
Ensembl
PMID:18174455 GO_REF:0000107 NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,697,032...3,718,234
JBrowse link
positive regulation of mast cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1a Fc epsilon receptor Ia acts_upstream_of_or_within ISO (PMID:9000133) RGD PMID:9000133 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351
JBrowse link
G Fcer1g Fc epsilon receptor Ig acts_upstream_of_or_within ISO MGI:2384004 (PMID:14764707) RGD PMID:14764707 NCBI chr13:86,181,908...86,186,766
Ensembl chr13:83,649,449...83,671,443
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO (PMID:20100931) RGD PMID:20100931 NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:24586680)
UniProt
RGD
PMID:24586680 GO_REF:0000024 NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:62,361,822...62,402,733
JBrowse link
G Syk spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2384078 (PMID:9000133)
Ensembl
RGD
PMID:9000133 GO_REF:0000107 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410
JBrowse link
positive regulation of myeloid dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk4 calcium/calmodulin-dependent protein kinase IV NOT|involved_in ISO (PMID:17909078) RGD PMID:17909078 NCBI chr18:24,857,152...25,076,054
Ensembl chr18:24,585,269...24,802,487
JBrowse link
G Ddx1 DEAD-box helicase 1 involved_in ISO (PMID:21703541) RGD PMID:21703541 NCBI chr 6:41,725,365...41,756,236
Ensembl chr 6:35,996,469...36,027,365
JBrowse link
G Ddx21 DExD-box helicase 21 involved_in ISO (PMID:21703541) RGD PMID:21703541 NCBI chr20:31,077,044...31,097,238
Ensembl chr20:30,534,319...30,554,543
JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO (PMID:21703541) RGD PMID:21703541 NCBI chr 2:149,006,089...149,044,192
Ensembl chr 2:146,856,469...146,894,572
JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISS
ISO
GO_REF:0000024
(PMID:21703541)
UniProt
RGD
PMID:21703541 GO_REF:0000024 NCBI chr 3:138,904,673...138,919,129
Ensembl chr 3:118,451,743...118,466,094
JBrowse link
G Rig1 RNA sensor RIG-1 involved_in ISO (PMID:21703541) RGD PMID:21703541 NCBI chr 5:60,117,398...60,165,995
Ensembl chr 5:55,321,235...55,370,819
JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 involved_in ISO (PMID:21703541) RGD PMID:21703541 NCBI chr 9:1,189,717...1,197,730
Ensembl chr 9:1,102,366...1,123,147
JBrowse link
positive regulation of myeloid leukocyte cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:11756671) RGD PMID:11756671 NCBI chr20:12,767,138...12,791,222
Ensembl chr20:12,790,902...12,799,504
Ensembl chr 4:12,790,902...12,799,504
JBrowse link
positive regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd160 CD160 molecule involved_in ISO (PMID:17307798) RGD PMID:17307798 NCBI chr 2:187,029,654...187,042,447
Ensembl chr 2:184,340,599...184,375,834
JBrowse link
G Cd226 CD226 molecule acts_upstream_of_or_within ISO MGI:4454325 (PMID:24658051) RGD PMID:24658051 NCBI chr18:84,723,330...84,819,836
Ensembl chr18:82,450,568...82,543,051
JBrowse link
G Clnk cytokine-dependent hematopoietic cell linker involved_in ISO (PMID:16439675) RGD PMID:16439675 NCBI chr14:76,136,446...76,315,364
Ensembl chr14:71,873,105...72,101,208
JBrowse link
G Gimap5 GTPase, IMAP family member 5 IMP RGD PMID:15100275 RGD:2303778 NCBI chr 4:79,025,151...79,031,917
Ensembl chr 4:77,687,564...77,703,086
JBrowse link
G Il21 interleukin 21 acts_upstream_of_or_within ISO (PMID:14764669) RGD PMID:14764669 NCBI chr 2:122,045,240...122,055,142
Ensembl chr 2:120,119,444...120,126,996
JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:30134159) RGD PMID:30134159 NCBI chr20:4,872,720...4,876,425 JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:27455421) RGD PMID:27455421 NCBI chr20:3,407,880...3,484,130 JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:16366734), (PMID:19304799), (PMID:23184984) RGD PMID:16366734 PMID:19304799 PMID:23184984 NCBI chr20:1,329,227...1,333,394
Ensembl chr20:1,287,521...1,328,117
JBrowse link
positive regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2 microglobulin involved_in ISO
IEA
(PMID:24643698)
GO_REF:0000107
RGD
Ensembl
PMID:24643698 GO_REF:0000107 NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Cd55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:16818763) RGD PMID:16818763 NCBI chr13:44,409,574...44,438,913
Ensembl chr13:41,857,395...41,885,831
JBrowse link
G Cd7 Cd7 molecule involved_in ISO (PMID:10652336) RGD PMID:10652336 NCBI chr10:106,304,046...106,306,963
Ensembl chr10:106,304,056...106,306,967
JBrowse link
G Fzd5 frizzled class receptor 5 involved_in ISO
IEA
(PMID:16601243)
GO_REF:0000107
RGD
Ensembl
PMID:16601243 GO_REF:0000107 NCBI chr 9:73,606,860...73,614,039
Ensembl chr 9:66,113,112...66,121,457
JBrowse link
G Malt1 MALT1 paracaspase involved_in ISO (PMID:15125833) RGD PMID:15125833 NCBI chr18:61,212,290...61,266,272
Ensembl chr18:58,942,299...58,994,260
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in ISO (PMID:15125833) RGD PMID:15125833 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G RT1-CE16 RT1 class I, locus CE16 involved_in ISO (PMID:24643698) RGD PMID:24643698 NCBI chr20:3,261,656...3,265,548
Ensembl chr20:3,257,123...3,279,563
JBrowse link
G Sash3 SAM and SH3 domain containing 3 acts_upstream_of_or_within ISO MGI:3716944 (PMID:16227612) RGD PMID:16227612 NCBI chr  X:132,204,717...132,219,421
Ensembl chr  X:127,326,859...127,341,519
JBrowse link
G Sectm1b secreted and transmembrane 1B involved_in ISO (PMID:22184754) RGD PMID:22184754 NCBI chr10:106,324,070...106,333,779
Ensembl chr10:106,325,203...106,333,769
JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:18354165), (PMID:9670042) RGD PMID:9670042 PMID:18354165 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:73,723,329...73,746,788
JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in ISO (PMID:15125833) RGD PMID:15125833 NCBI chr 3:28,740,098...28,764,752
Ensembl chr 3:8,341,951...8,366,538
JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO
IEA
(PMID:15125833)
GO_REF:0000107
RGD
Ensembl
PMID:15125833 GO_REF:0000107 NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:87,963,514...87,983,507
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:9029087) RGD PMID:9029087 NCBI chr13:79,781,784...79,785,440
Ensembl chr13:77,248,717...77,252,329
JBrowse link
positive regulation of T-helper 1 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid5a AT-rich interaction domain 5A involved_in ISO (PMID:27671645) RGD PMID:27671645 NCBI chr 9:46,030,513...46,058,729
Ensembl chr 9:38,534,590...38,547,597
JBrowse link
G Il18 interleukin 18 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:10653850)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:10653850 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il18r1 interleukin 18 receptor 1 involved_in ISO (PMID:10653850) RGD PMID:10653850 NCBI chr 9:50,223,274...50,257,370
Ensembl chr 9:42,727,869...42,760,715
JBrowse link
G Il1b interleukin 1 beta involved_in ISO
ISS
(PMID:10653850)
GO_REF:0000024
RGD
UniProt
PMID:10653850 GO_REF:0000024 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1r1 interleukin 1 receptor type 1 involved_in ISO
ISS
IEA
(PMID:10653850)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:10653850 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:42,504,735...42,579,937
JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (PMID:9126961) RGD PMID:9126961 NCBI chr13:86,802,708...86,837,890
Ensembl chr13:84,270,316...84,305,497
JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (PMID:10761931) RGD PMID:10761931 NCBI chr10:82,578,751...82,595,253
Ensembl chr10:82,082,322...82,098,831
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:9973465)
Ensembl
RGD
PMID:9973465 GO_REF:0000107 NCBI chr13:79,781,784...79,785,440
Ensembl chr13:77,248,717...77,252,329
JBrowse link
positive regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 Cd81 molecule involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:8766544)
GO_REF:0000107
(PMID:11046035)
UniProt
RGD
Ensembl
PMID:8766544 PMID:11046035 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:207,665,274...207,681,094
Ensembl chr 1:198,241,484...198,251,660
JBrowse link
G Dennd1b DENN domain containing 1B involved_in ISO (PMID:26774822) RGD PMID:26774822 NCBI chr13:53,096,717...53,324,372
Ensembl chr13:50,545,836...50,770,601
JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO (PMID:15087456) RGD PMID:15087456 NCBI chr17:73,544,234...73,575,670
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Il4 interleukin 4 involved_in ISO (PMID:20554961) RGD PMID:20554961 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:11159963) RGD PMID:11159963 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in ISO (PMID:26098997) RGD PMID:26098997 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Prkcz protein kinase C, zeta involved_in ISS
ISO
GO_REF:0000024
(PMID:15987782)
UniProt
RGD
PMID:15987782 GO_REF:0000024 NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:165,819,466...165,930,367
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:19047684)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:19047684 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:48,774,985...48,788,245
Ensembl chr 6:43,047,658...43,059,699
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:9973465)
Ensembl
RGD
PMID:9973465 GO_REF:0000107 NCBI chr13:79,781,784...79,785,440
Ensembl chr13:77,248,717...77,252,329
JBrowse link
regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO (PMID:19047410) RGD PMID:19047410 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tlr3 toll-like receptor 3 acts_upstream_of_or_within ISO (PMID:19047410) RGD PMID:19047410 NCBI chr16:53,554,916...53,572,321
Ensembl chr16:46,822,039...46,836,545
JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:19047410)
Ensembl
RGD
PMID:19047410 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr9 toll-like receptor 9 acts_upstream_of_or_within ISO (PMID:19047410) RGD PMID:19047410 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Litaf lipopolysaccharide-induced TNF factor acts_upstream_of_or_within ISO MGI:3687962 (PMID:16954198) RGD PMID:16954198 NCBI chr10:5,163,258...5,199,930
Ensembl chr10:4,625,552...4,692,763
JBrowse link
G Ube2j1 ubiquitin-conjugating enzyme E2, J1 acts_upstream_of_or_within ISO MGI:109298 (PMID:24020373) RGD PMID:24020373 NCBI chr 5:47,422,476...47,441,476
Ensembl chr 5:47,422,587...47,441,461
JBrowse link
regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calhm6 calcium homeostasis modulator family member 6 involved_in ISO (PMID:36861806) RGD PMID:36861806 NCBI chr20:26,638,721...26,640,466
Ensembl chr20:26,095,592...26,097,278
JBrowse link
regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl20 C-C motif chemokine ligand 20 NOT|involved_in ISO (PMID:19050256) RGD PMID:19050256 NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:28507030)
UniProt
RGD
PMID:28507030 GO_REF:0000024 NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in IBA
ISO
GO_REF:0000033
(PMID:28052249)
GO_Central
RGD
PMID:28052249 GO_REF:0000033 NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:157,070,642...157,104,206
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 involved_in ISO
IEA
ISS
(PMID:20656926)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:20656926 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:104,918,462...104,949,453
Ensembl chr 1:95,782,000...95,812,532
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20553
    immune system process 3120
      immune response 2219
        cytokine production involved in immune response 134
          regulation of cytokine production involved in immune response 134
            negative regulation of cytokine production involved in immune response + 36
            positive regulation of cytokine production involved in immune response + 92
            regulation of B cell cytokine production + 0
            regulation of T cell cytokine production + 40
            regulation of dendritic cell cytokine production + 18
            regulation of macrophage cytokine production + 45
            regulation of mast cell cytokine production + 8
            regulation of natural killer cell cytokine production + 10
Path 2
Term Annotations click to browse term
  biological_process 20553
    biological regulation 13833
      regulation of biological process 13387
        regulation of cellular process 13023
          regulation of metabolic process 6832
            regulation of biosynthetic process 5630
              regulation of macromolecule biosynthetic process 5425
                regulation of gene expression 5311
                  regulation of production of molecular mediator of immune response 216
                    regulation of cytokine production involved in immune response 134
                      negative regulation of cytokine production involved in immune response + 36
                      positive regulation of cytokine production involved in immune response + 92
                      regulation of B cell cytokine production + 0
                      regulation of T cell cytokine production + 40
                      regulation of dendritic cell cytokine production + 18
                      regulation of macrophage cytokine production + 45
                      regulation of mast cell cytokine production + 8
                      regulation of natural killer cell cytokine production + 10
paths to the root