Gene: Twist2 (twist family bHLH transcription factor 2) Rattus norvegicus
Symbol: Twist2
Name: twist family bHLH transcription factor 2
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor activity (ortholog); protein domain specific binding (ortholog); INVOLVED IN negative regulation of apoptotic process; cornea development in camera-type eye (ortholog); embryonic cranial skeleton morphogenesis (ortholog); ASSOCIATED WITH ablepharon macrostomia syndrome (ortholog); Barber-Say syndrome (ortholog); Facial Ectodermal Dysplasia (ortholog); FOUND IN cytoplasm (ortholog); nucleolus (ortholog); nucleus (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; ammonium chloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: dermo-1 protein; Dermo1; twist basic helix-loop-helix transcription factor 2; twist homolog 2; twist homolog 2 (Drosophila); twist-related protein 2
Homo sapiens (human) : TWIST2 (twist family bHLH transcription factor 2)  HGNC  Alliance
Mus musculus (house mouse) : Twist2 (twist basic helix-loop-helix transcription factor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Twist2 (twist family bHLH transcription factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TWIST2 (twist family bHLH transcription factor 2)
Canis lupus familiaris (dog) : TWIST2 (twist family bHLH transcription factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Twist2 (twist family bHLH transcription factor 2)
Sus scrofa (pig) : TWIST2 (twist family bHLH transcription factor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0998,924,134 - 98,968,510 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0998,599,201 - 98,642,827 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4991,016,450 - 91,058,863 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1991,221,218 - 91,263,067 (+)NCBI
Celera989,915,377 - 89,958,630 (+)NCBICelera
Cytogenetic Map9q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Twist2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621286
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE