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Gene: Gimap5 (GTPase, IMAP family member 5) Rattus norvegicus
Symbol: Gimap5
Name: GTPase, IMAP family member 5
Description: Predicted to have GTP binding activity. Involved in several processes, including leukocyte differentiation; positive regulation of lymphocyte mediated immunity; and regulation of T cell activation. Localizes to the mitochondrion. Used to study lymphopenia and type 1 diabetes mellitus. Orthologous to several human genes including GIMAP5 (GTPase, IMAP family member 5); INTERACTS WITH (S)-amphetamine; 2,6-dinitrotoluene; 7,12-dimethyltetraphene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GTPase IMAP family member 5; IAN-4; IAN4; Ian4l1; IAN5; immune associated nucleotide 4 like 1; immune associated nucleotide 4 like 1 (mouse); immunity-associated nucleotide 4 protein; immunity-associated nucleotide 4-like 1 protein; lymphopenia; lymphopenia gene; lyp
Homo sapiens (human) : GIMAP5 (GTPase, IMAP family member 5)  HGNC  Alliance
Mus musculus (house mouse) : Gimap5 (GTPase, IMAP family member 5)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : GIMAP5 (GTPase, IMAP family member 5)
Canis lupus familiaris (dog) : LOC100687459 (GTPase IMAP family member 5)
Sus scrofa (pig) : GIMAP5 (GTPase, IMAP family member 5)
more info ...
Is Marker For: Strains:   BB.SHR-(D4Got41-Gimap5)/K   BBDP.BBDR-Gimap5/Sunn   BBDP.BBDR-Gimap5, WF-(D13Rat124-D13Mgh5)/Sunn  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0478,377,228 - 78,386,683 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl478,378,144 - 78,385,577 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04143,066,311 - 143,073,003 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4476,836,521 - 76,843,214 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1477,112,650 - 77,119,327 (+)NCBI
Celera472,631,351 - 72,638,043 (+)NCBICelera
Cytogenetic Map4q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gimap5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 628871
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.