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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of macrophage cytokine production
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Accession:GO:0060907 term browser browse the term
Definition:Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.



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positive regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card9 caspase recruitment domain family, member 9 acts_upstream_of_or_within ISO MGI:3698412 (PMID:17187069) RGD PMID:17187069 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
JBrowse link
G Casp1 caspase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:18490713)
Ensembl
RGD
PMID:18490713 GO_REF:0000107 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp4 caspase 4 acts_upstream_of_or_within ISO MGI:1931465|MGI:2653833 (PMID:22002608) RGD PMID:22002608 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Cd36 CD36 molecule involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2447190|MGI:3573941 (PMID:15690042), (PMID:16061696)
Ensembl
RGD
PMID:15690042 PMID:16061696 GO_REF:0000107 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cd74 CD74 molecule involved_in ISS
ISO
IBA
IEA
GO_REF:0000024
(MGI:4943655|PMID:19413900)
GO_REF:0000033
GO_REF:0000118
BHF-UCL
RGD
GO_Central
TreeGrafter
PMID:19413900 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 MGI:4943655 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Gprc5b G protein-coupled receptor, class C, group 5, member B involved_in ISO (MGI:5545939|PMID:23169819) RGD PMID:23169819 MGI:5545939 NCBI chr 1:173,316,904...173,340,933
Ensembl chr 1:173,316,907...173,340,932
JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:9348310) RGD PMID:9348310 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:6391873|PMID:22733818) RGD PMID:22733818 MGI:6391873 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 acts_upstream_of_or_within ISO (PMID:24020373) RGD PMID:24020373 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457
JBrowse link
G Mir324 microRNA 324 acts_upstream_of_or_within ISO (PMID:24882011) RGD PMID:24882011 NCBI chr10:54,734,680...54,734,762
Ensembl chr10:54,734,678...54,734,766
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of_or_within ISO MGI:2147032|MGI:2385681 (PMID:10607756), (PMID:11067888), (PMID:12872135) RGD PMID:10607756 PMID:11067888 PMID:12872135 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of_or_within ISO MGI:2429397|MGI:2674231 (PMID:18261938) RGD PMID:18261938 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:1341839|MGI:2680581|MGI:3529594 (PMID:14560001), (PMID:15220916), (PMID:15692051), (PMID:18261938) RGD PMID:14560001 PMID:15220916 PMID:15692051 PMID:18261938 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:2386080|MGI:3606250 (PMID:11016935), (PMID:18490713) RGD PMID:11016935 PMID:18490713 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Panx1 Pannexin 1 acts_upstream_of_or_within ISO (PMID:18490713) RGD PMID:18490713 NCBI chr 8:11,851,176...11,889,774
Ensembl chr 8:11,850,730...11,889,774
JBrowse link
G Plcg2 phospholipase C, gamma 2 acts_upstream_of
involved_in
ISO
IEA
(MGI:5300086|PMID:22041900)
GO_REF:0000107
RGD
Ensembl
PMID:22041900 GO_REF:0000107 MGI:5300086 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
JBrowse link
G Pycard PYD and CARD domain containing acts_upstream_of_or_within ISO MGI:107700|MGI:2653833 (PMID:22002608) RGD PMID:22002608 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO MGI:2660793 (PMID:11894098), (PMID:18261938) RGD PMID:11894098 PMID:18261938 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:19304799) RGD PMID:19304799 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
G Rtn4 reticulon 4 involved_in ISS
ISO
GO_REF:0000024
(MGI:4366092|PMID:19805174)
UniProt
RGD
PMID:19805174 GO_REF:0000024 MGI:4366092 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686
JBrowse link
G Sema7a semaphorin 7A (John Milton Hagen blood group) involved_in ISO
IBA
(MGI:3710037|PMID:17377534)
GO_REF:0000033
RGD
GO_Central
PMID:17377534 GO_REF:0000033 MGI:3710037 NCBI chr 8:58,348,448...58,370,536
Ensembl chr 8:58,348,448...58,370,536
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA
(MGI:5319292|PMID:22315447)
GO_REF:0000107
RGD
Ensembl
PMID:22315447 GO_REF:0000107 MGI:5319292 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Spon2 spondin 2 acts_upstream_of_or_within ISO MGI:3026870 (PMID:14691481) RGD PMID:14691481 NCBI chr14:77,505,695...77,518,001
Ensembl chr14:77,511,901...77,517,996
JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO MGI:108005|MGI:2679794|MGI:3029019 (PMID:12855817), (PMID:12872135) RGD PMID:12855817 PMID:12872135 NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147
JBrowse link
G Tirap TIR domain containing adaptor protein acts_upstream_of_or_within ISO MGI:3573942 (PMID:15690042) RGD PMID:15690042 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432
JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO MGI:2178675|MGI:2674036 (PMID:10549626), (PMID:11067888), (PMID:15690042), (PMID:18261938) RGD PMID:10549626 PMID:11067888 PMID:15690042 PMID:18261938 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tlr3 toll-like receptor 3 acts_upstream_of_or_within ISO MGI:3690535 (PMID:12855817), (PMID:18261938) RGD PMID:12855817 PMID:18261938 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857718|MGI:1860755|MGI:1860885 (PMID:10549626), (PMID:10607756), (PMID:10623794), (PMID:14691481), (PMID:15661922), (PMID:18261938), (PMID:21609717)
Ensembl
RGD
PMID:10549626 PMID:10607756 PMID:10623794 PMID:14691481 PMID:15661922 More... GO_REF:0000107 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr7 toll-like receptor 7 acts_upstream_of_or_within ISO (PMID:18261938) RGD PMID:18261938 NCBI chr  X:27,027,380...27,054,309
Ensembl chr  X:27,027,425...27,054,754
JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO
IEA
(PMID:18174455)
GO_REF:0000107
RGD
Ensembl
PMID:18174455 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    multicellular organismal process 8921
      cytokine production 918
        cytokine production involved in immune response 131
          myeloid leukocyte cytokine production 61
            macrophage cytokine production 45
              positive regulation of macrophage cytokine production 30
Path 2
Term Annotations click to browse term
  biological_process 20413
    biological regulation 13755
      regulation of biological process 13322
        regulation of metabolic process 6641
          regulation of biosynthetic process 5478
            regulation of cellular biosynthetic process 5386
              regulation of macromolecule biosynthetic process 5286
                regulation of gene expression 5170
                  regulation of cytokine production 910
                    positive regulation of cytokine production 537
                      positive regulation of cytokine production involved in immune response 91
                        positive regulation of myeloid leukocyte cytokine production involved in immune response 43
                          positive regulation of macrophage cytokine production 30
paths to the root