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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cytokine production involved in immune response
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Accession:GO:0002719 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response.
Synonyms:narrow_synonym: negative regulation of cytokine biosynthetic process involved in immune response;   negative regulation of cytokine secretion involved in immune response
 related_synonym: down regulation of cytokine production during immune response;   downregulation of cytokine production during immune response;   inhibition of cytokine production during immune response;   negative regulation of cytokine production during immune response
 alt_id: GO:0002740;   GO:0002743


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negative regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4437182|PMID:20060382)
Ensembl
RGD
PMID:20060382 GO_REF:0000107 MGI:4437182 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
JBrowse link
G Apoa1 apolipoprotein A1 involved_in ISO (PMID:12458630) RGD PMID:12458630 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:12458630) RGD PMID:12458630 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
JBrowse link
G Il10 interleukin 10 involved_in ISS
ISO
GO_REF:0000024
(PMID:10443688)
UniProt
RGD
PMID:10443688 GO_REF:0000024 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:10443688) RGD PMID:10443688 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
negative regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jak3 Janus kinase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:3719947|PMID:16020505)
BHF-UCL
RGD
PMID:16020505 GO_REF:0000024 MGI:3719947 NCBI chr16:20,107,471...20,120,678
Ensembl chr16:20,109,200...20,120,668
JBrowse link
negative regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cuedc2 CUE domain containing 2 acts_upstream_of_or_within ISO MGI:5635142 (MGI:5576401|PMID:24882011)
(PMID:24882011)
RGD PMID:24882011 MGI:5576401 NCBI chr 1:266,078,107...266,087,057
Ensembl chr 1:266,078,108...266,086,299
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in ISO (MGI:2183694|PMID:12150927) RGD PMID:12150927 MGI:2183694 NCBI chr 7:64,922,830...64,982,224
Ensembl chr 7:64,923,615...64,982,281
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS
(PMID:20875417)
GO_REF:0000024
RGD
AgBase
PMID:20875417 GO_REF:0000024 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:20875417)
AgBase
RGD
PMID:20875417 GO_REF:0000024 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISO
ISS
(PMID:20875417)
GO_REF:0000024
RGD
AgBase
PMID:20875417 GO_REF:0000024 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
negative regulation of mast cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:2158436 (MGI:3581006|PMID:15950739) RGD PMID:15950739 MGI:3581006 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:17234154 RGD:1601626 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
negative regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd96 CD96 molecule acts_upstream_of_or_within ISO MGI:5617136 (MGI:5569209|PMID:24658051) RGD PMID:24658051 MGI:5569209 NCBI chr11:57,108,757...57,183,855
Ensembl chr11:57,108,956...57,183,270
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991
JBrowse link
negative regulation of plasmacytoid dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bst2 bone marrow stromal cell antigen 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:19564354)
UniProt
RGD
PMID:19564354 GO_REF:0000024 NCBI chr16:19,938,781...19,942,353
Ensembl chr16:19,938,784...19,942,353
JBrowse link
negative regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 involved_in ISO (PMID:15466453), (PMID:23169781) RGD PMID:15466453 PMID:23169781 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Hfe homeostatic iron regulator involved_in ISO UniProtKB:P04439 (PMID:24643698) RGD PMID:24643698 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:18420485) RGD PMID:18420485 NCBI chr 1:73,393,854...73,399,448
Ensembl chr 1:73,393,850...73,399,579
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991
JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (MGI:5700313|PMID:11477403) RGD PMID:11477403 MGI:5700313 NCBI chr13:90,184,545...90,219,170
Ensembl chr13:90,184,569...90,219,217
JBrowse link
G Smad7 SMAD family member 7 involved_in IEA
ISO
GO_REF:0000107
(MGI:5634593|PMID:25642768)
Ensembl
RGD
PMID:25642768 GO_REF:0000107 MGI:5634593 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157
JBrowse link
G Vsir V-set immunoregulatory receptor acts_upstream_of_or_within ISO (MGI:5292805|PMID:21383057) RGD PMID:21383057 MGI:5292805 NCBI chr20:29,897,543...29,923,381
Ensembl chr20:29,897,594...29,919,998
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:10887101) RGD PMID:10887101 NCBI chr13:83,199,402...83,202,845
Ensembl chr13:83,199,264...83,202,864
JBrowse link
negative regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in ISO (MGI:5908339|PMID:19360123) RGD PMID:19360123 MGI:5908339 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (PMID:20554961) RGD PMID:20554961 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:5543347|PMID:23616576) RGD PMID:23616576 MGI:5543347 NCBI chr10:85,032,799...85,049,331
Ensembl chr10:85,032,799...85,049,331
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    immune system process 2886
      production of molecular mediator of immune response 206
        negative regulation of production of molecular mediator of immune response 39
          negative regulation of cytokine production involved in immune response 26
            negative regulation of B cell cytokine production 0
            negative regulation of T cell cytokine production + 11
            negative regulation of dendritic cell cytokine production + 2
            negative regulation of macrophage cytokine production 5
            negative regulation of mast cell cytokine production 2
            negative regulation of natural killer cell cytokine production 2
Path 2
Term Annotations click to browse term
  biological_process 19612
    metabolic process 11881
      organic substance metabolic process 11416
        macromolecule metabolic process 9872
          gene expression 6287
            cytokine production 771
              regulation of cytokine production 764
                negative regulation of cytokine production 290
                  negative regulation of cytokine production involved in immune response 26
                    negative regulation of B cell cytokine production 0
                    negative regulation of T cell cytokine production + 11
                    negative regulation of dendritic cell cytokine production + 2
                    negative regulation of macrophage cytokine production 5
                    negative regulation of mast cell cytokine production 2
                    negative regulation of natural killer cell cytokine production 2
paths to the root