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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of production of molecular mediator of immune response
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Accession:GO:0002700 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response.


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negative regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spink5 serine peptidase inhibitor, Kazal type 5 involved_in ISO (MGI:3770082|PMID:17012259) RGD PMID:17012259 MGI:3770082 NCBI chr18:36,264,452...36,333,143
Ensembl chr18:36,264,452...36,332,185 		JBrowse link
negative regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:4437182|PMID:20060382)		 Ensembl
RGD		 PMID:20060382 GO_REF:0000107 MGI:4437182 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Apoa1 apolipoprotein A1 involved_in ISO
IEA		 (PMID:12458630)
GO_REF:0000107		 RGD
Ensembl		 PMID:12458630 GO_REF:0000107 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:12458630) RGD PMID:12458630 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355 		JBrowse link
G Il10 interleukin 10 involved_in ISS
ISO		 GO_REF:0000024
(PMID:10443688)		 UniProt
RGD		 PMID:10443688 GO_REF:0000024 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:10443688) RGD PMID:10443688 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
negative regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jak3 Janus kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3719947|PMID:16020505)		 BHF-UCL
RGD		 PMID:16020505 GO_REF:0000024 MGI:3719947 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
negative regulation of immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd22 CD22 molecule involved_in ISO UniProtKB:Q80ZE3 (MGI:4453395|PMID:20200274) RGD PMID:20200274 MGI:4453395 NCBI chr 1:86,116,376...86,132,782
Ensembl chr 1:86,117,459...86,132,322 		JBrowse link
G Fcgr2b Fc gamma receptor 2B acts_upstream_of_or_within ISO MGI:1857166 (MGI:3608295|PMID:12385742) RGD PMID:12385742 MGI:3608295 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Ifnb1 interferon beta 1 IDA RGD PMID:10494101 RGD:401854240 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2653910 (MGI:3589858|PMID:15944273)		 Ensembl
RGD		 PMID:15944273 GO_REF:0000107 MGI:3589858 NCBI chr  X:111,002,590...111,074,053
Ensembl chr  X:111,002,592...111,072,381 		JBrowse link
G Il33 interleukin 33 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P08226 (MGI:3775141|PMID:18268038)		 Ensembl
RGD		 PMID:18268038 GO_REF:0000107 MGI:3775141 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit IMP RGD PMID:22981234 RGD:8696027 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Siglec10 sialic acid binding Ig-like lectin 10 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 1:93,817,301...93,826,376
Ensembl chr 1:93,817,335...93,825,931 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO (MGI:3840374|PMID:19328063) RGD PMID:19328063 MGI:3840374 NCBI chr 7:130,527,313...130,542,567
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
G Zpbp2 zona pellucida binding protein 2 acts_upstream_of_or_within ISO MGI:3762590 (MGI:6150730|PMID:29536159) RGD PMID:29536159 MGI:6150730 NCBI chr10:83,558,772...83,567,511
Ensembl chr10:83,559,016...83,567,508 		JBrowse link
negative regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp3 poly (ADP-ribose) polymerase family, member 3 involved_in ISO (MGI:6214451|PMID:26000965) RGD PMID:26000965 MGI:6214451 NCBI chr 8:107,111,010...107,117,073
Ensembl chr 8:107,111,012...107,116,782 		JBrowse link
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Da2-19 uncharacterized LOC302729 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:44,820,693...44,837,935
Ensembl chr  X:44,820,820...44,837,934 		JBrowse link
G Thoc1 THO complex subunit 1 involved_in ISO (MGI:5520039|PMID:22144908) RGD PMID:22144908 MGI:5520039 NCBI chr18:983,824...1,019,123
Ensembl chr18:983,824...1,019,114 		JBrowse link
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:103034|MGI:2158438 (MGI:1345885|PMID:10490661) RGD PMID:10490661 MGI:1345885 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO MGI:3696705 (MGI:3695768|PMID:16275384) RGD PMID:16275384 MGI:3695768 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3695433 (MGI:3694584|PMID:17137798)
GO_REF:0000107		 RGD
Ensembl		 PMID:17137798 GO_REF:0000107 MGI:3694584 NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311 		JBrowse link
negative regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2180086 (MGI:1930064|PMID:11168643)
GO_REF:0000107		 RGD
Ensembl		 PMID:11168643 GO_REF:0000107 MGI:1930064 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Atg9a autophagy related 9A acts_upstream_of_or_within ISO (MGI:5569198|PMID:24670807) RGD PMID:24670807 MGI:5569198 NCBI chr 9:76,677,403...76,688,050
Ensembl chr 9:76,677,404...76,687,986 		JBrowse link
G Axl Axl receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:107670 (MGI:3721468|PMID:16831897) RGD PMID:16831897 MGI:3721468 NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265 		JBrowse link
G Cuedc2 CUE domain containing 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:5635142 (MGI:5576401|PMID:24882011)
GO_REF:0000107
(PMID:24882011)		 RGD
Ensembl		 PMID:24882011 GO_REF:0000107 MGI:5576401 NCBI chr 1:245,192,057...245,200,594
Ensembl chr 1:245,192,063...245,200,339 		JBrowse link
G Epx eosinophil peroxidase acts_upstream_of_or_within ISO MGI:2182952 (MGI:3656344|PMID:16926417) RGD PMID:16926417 MGI:3656344 NCBI chr10:72,666,865...72,677,952
Ensembl chr10:72,666,865...72,677,952 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in ISO (MGI:2183694|PMID:12150927) RGD PMID:12150927 MGI:2183694 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Nlrx1 NLR family member X1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:5141085 (MGI:5050761|PMID:21703540)
GO_REF:0000107		 RGD
Ensembl		 PMID:21703540 GO_REF:0000107 MGI:5050761 NCBI chr 8:44,588,476...44,606,678
Ensembl chr 8:44,590,048...44,606,484 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:2680581 (MGI:3050756|PMID:15220916) RGD PMID:15220916 MGI:3050756 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Prg2 proteoglycan 2, pro eosinophil major basic protein acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3027719 (MGI:3656344|PMID:16926417)
GO_REF:0000107		 RGD
Ensembl		 PMID:16926417 GO_REF:0000107 MGI:3656344 NCBI chr 3:70,062,535...70,066,102
Ensembl chr 3:70,062,535...70,066,101 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS		 (PMID:20875417)
GO_REF:0000024		 RGD
AgBase		 PMID:20875417 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20875417)		 UniProt
RGD		 PMID:20875417 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISO
ISS		 (PMID:20875417)
GO_REF:0000024		 RGD
AgBase		 PMID:20875417 GO_REF:0000024 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:104685 (MGI:3721468|PMID:16831897) RGD PMID:16831897 MGI:3721468 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
G Twist2 twist family bHLH transcription factor 2 acts_upstream_of_or_within ISO MGI:3044412|MGI:98872 (MGI:3721468|PMID:16831897) RGD PMID:16831897 MGI:3721468 NCBI chr 9:92,374,740...92,419,222
Ensembl chr 9:92,374,574...92,419,222 		JBrowse link
negative regulation of mast cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:2158436 (MGI:3581006|PMID:15950739) RGD PMID:15950739 MGI:3581006 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:17234154 RGD:1601626 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO MGI:3051384 (MGI:3620385|PMID:16533754) RGD PMID:16533754 MGI:3620385 NCBI chr12:26,459,190...26,503,790
Ensembl chr12:26,460,175...26,503,744 		JBrowse link
negative regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd96 CD96 molecule acts_upstream_of_or_within ISO MGI:5617136 (MGI:5569209|PMID:24658051) RGD PMID:24658051 MGI:5569209 NCBI chr11:54,702,290...54,776,618
Ensembl chr11:54,702,290...54,776,621 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
negative regulation of plasmacytoid dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bst2 bone marrow stromal cell antigen 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19564354)		 UniProt
RGD		 PMID:19564354 GO_REF:0000024 NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979 		JBrowse link
negative regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 involved_in ISO (PMID:15466453), (PMID:23169781) RGD PMID:15466453 PMID:23169781 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Hfe homeostatic iron regulator involved_in ISO UniProtKB:P04439 (PMID:24643698) RGD PMID:24643698 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:18420485) RGD PMID:18420485 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (MGI:5700313|PMID:11477403) RGD PMID:11477403 MGI:5700313 NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497 		JBrowse link
G Smad7 SMAD family member 7 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5634593|PMID:25642768)		 Ensembl
RGD		 PMID:25642768 GO_REF:0000107 MGI:5634593 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Vsir V-set immunoregulatory receptor acts_upstream_of_or_within ISO (MGI:5292805|PMID:21383057) RGD PMID:21383057 MGI:5292805 NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:10887101) RGD PMID:10887101 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
negative regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in ISO
IEA		 (MGI:5908339|PMID:19360123)
GO_REF:0000107		 RGD
Ensembl		 PMID:19360123 GO_REF:0000107 MGI:5908339 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (PMID:20554961) RGD PMID:20554961 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:1354779|PMID:10761931), (MGI:5543347|PMID:23616576) RGD PMID:10761931 PMID:23616576 MGI:1354779 MGI:5543347 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831 		JBrowse link
positive regulation of antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (MGI:3775881|PMID:18167348) RGD PMID:18167348 MGI:3775881 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
positive regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klk1c10 kallikrein 1-related peptidase C10 involved_in ISO (PMID:18714013) RGD PMID:18714013 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052 		JBrowse link
G Klk5 kallikrein related-peptidase 5 involved_in ISO
IBA		 (PMID:17012259)
PMID:21873635		 RGD PMID:17012259 PMID:21873635 RGD:13792537 NCBI chr 1:94,296,574...94,304,768
Ensembl chr 1:94,296,168...94,304,666 		JBrowse link
G Klk7 kallikrein-related peptidase 7 involved_in IEA
ISO		 GO_REF:0000107
(PMID:17012259)		 Ensembl
RGD		 PMID:17012259 GO_REF:0000107 NCBI chr 1:94,267,170...94,271,361
Ensembl chr 1:94,266,605...94,271,332 		JBrowse link
G Pgc progastricsin involved_in ISO (PMID:12759353) RGD PMID:12759353 NCBI chr 9:13,257,462...13,265,682
Ensembl chr 9:13,257,462...13,265,682 		JBrowse link
positive regulation of antimicrobial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il17a interleukin 17A involved_in IEA
ISO		 GO_REF:0000107
(MGI:3828868|PMID:19144317)		 Ensembl
RGD		 PMID:19144317 GO_REF:0000107 MGI:3828868 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il17f interleukin 17F involved_in IEA
ISO		 GO_REF:0000107
(MGI:3828868|PMID:19144317)		 Ensembl
RGD		 PMID:19144317 GO_REF:0000107 MGI:3828868 NCBI chr 9:23,190,094...23,201,482
Ensembl chr 9:23,190,100...23,201,482 		JBrowse link
positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:3529594 (MGI:3528786|PMID:15692051) RGD PMID:15692051 MGI:3528786 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
positive regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec7a C-type lectin domain containing 7A involved_in ISO (MGI:5803730|PMID:27288407) RGD PMID:27288407 MGI:5803730 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Defb43 defensin beta 43 involved_in ISO (PMID:26649771) RGD PMID:26649771 NCBI chr15:37,271,888...37,276,782
Ensembl chr15:37,272,008...37,276,626 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11441110)		 UniProt
RGD		 PMID:11441110 GO_REF:0000024 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Ffar2 free fatty acid receptor 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5575446|PMID:23665276)		 UniProt
RGD		 PMID:23665276 GO_REF:0000024 MGI:5575446 NCBI chr 1:86,071,855...86,075,049
Ensembl chr 1:86,072,184...86,075,033 		JBrowse link
G Ffar3 free fatty acid receptor 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5575446|PMID:23665276)		 UniProt
RGD		 PMID:23665276 GO_REF:0000024 MGI:5575446 NCBI chr 1:86,105,388...86,106,728
Ensembl chr 1:86,104,920...86,106,849 		JBrowse link
G Hk1 hexokinase 1 involved_in ISO
IEA		 (MGI:5790524|PMID:27374331)
GO_REF:0000107		 RGD
Ensembl		 PMID:27374331 GO_REF:0000107 MGI:5790524 NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131 		JBrowse link
G Inava innate immunity activator involved_in ISO (PMID:28436939) RGD PMID:28436939 NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729 		JBrowse link
G Irf5 interferon regulatory factor 5 involved_in ISO (PMID:29046356) RGD PMID:29046356 NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267 		JBrowse link
G Lacc1 laccase domain containing 1 involved_in ISO (PMID:28593945) RGD PMID:28593945 NCBI chr15:52,390,267...52,407,630
Ensembl chr15:52,395,183...52,407,545 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:6391873|PMID:22733818) RGD PMID:22733818 MGI:6391873 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in ISO (MGI:5790524|PMID:27374331) RGD PMID:27374331 MGI:5790524 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO (PMID:16260731) RGD PMID:16260731 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (MGI:5803730|PMID:27288407) RGD PMID:27288407 MGI:5803730 NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (MGI:3703830|PMID:17346996) RGD PMID:17346996 MGI:3703830 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
G Tek TEK receptor tyrosine kinase acts_upstream_of_or_within ISO (MGI:4437182|PMID:20060382) RGD PMID:20060382 MGI:4437182 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:4940320 (MGI:4881849|PMID:21236258)
PMID:21873635		 RGD PMID:21236258 PMID:21873635 MGI:4881849, RGD:13792537 NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703 		JBrowse link
G Trim6 tripartite motif containing 6 involved_in ISO (PMID:24882218) RGD PMID:24882218 NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:18174455) RGD PMID:18174455 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
positive regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec7a C-type lectin domain containing 7A involved_in ISO (MGI:3844414|PMID:19136564), (MGI:5803730|PMID:27288407) RGD PMID:19136564 PMID:27288407 MGI:3844414 MGI:5803730 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO (MGI:3796803|PMID:18454155) RGD PMID:18454155 MGI:3796803 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 IDA RGD PMID:16818757 RGD:1600784 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3844414|PMID:19136564)		 Ensembl
RGD		 PMID:19136564 GO_REF:0000107 MGI:3844414 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (MGI:5803730|PMID:27288407) RGD PMID:27288407 MGI:5803730 NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171 		JBrowse link
positive regulation of granzyme A production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:18832695) RGD PMID:18832695 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
positive regulation of granzyme B production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd244 CD244 molecule involved_in ISO (PMID:11714776) RGD PMID:11714776 NCBI chr13:84,051,339...84,082,864
Ensembl chr13:84,052,493...84,074,492 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in IBA
ISO		 PMID:21873635
(MGI:5562517|PMID:23871208)		 RGD PMID:23871208 PMID:21873635 MGI:5562517, RGD:13792537 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:18832695) RGD PMID:18832695 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
positive regulation of immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase IMP RGD PMID:28352114 RGD:151665126 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Cd37 CD37 molecule acts_upstream_of_or_within ISO MGI:2386160 (MGI:1860745|PMID:10891477) RGD PMID:10891477 MGI:1860745 NCBI chr 1:95,719,171...95,724,662
Ensembl chr 1:95,719,190...95,724,648 		JBrowse link
G Cd86 CD86 molecule involved_in ISO (MGI:5461234|PMID:23241883) RGD PMID:23241883 MGI:5461234 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO MGI:3053071|MGI:5609428 (MGI:5451119|PMID:23123061) RGD PMID:23123061 MGI:5451119 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 involved_in ISO (MGI:3777853|PMID:12023368) RGD PMID:12023368 MGI:3777853 NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5644772|PMID:25222125)		 UniProt
RGD		 PMID:25222125 GO_REF:0000024 MGI:5644772 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063 		JBrowse link
G Ephb2 Eph receptor B2 involved_in ISO (PMID:24803541) RGD PMID:24803541 NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059 		JBrowse link
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO MGI:3711150 (MGI:3662963|PMID:16819554) RGD PMID:16819554 MGI:3662963 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Gpi glucose-6-phosphate isomerase involved_in ISO (PMID:3020690) RGD PMID:3020690 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086 		JBrowse link
G Hpx hemopexin acts_upstream_of_or_within ISO MGI:2447193 (MGI:3807609|PMID:18641331) RGD PMID:18641331 MGI:3807609 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328 		JBrowse link
G Il10 interleukin 10 acts_upstream_of ISO UniProtKB:P60568 (PMID:22962438) RGD PMID:22962438 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il13 interleukin 13 acts_upstream_of_or_within IDA
ISO		 IgE production after infection
MGI:1931804|MGI:96556 (MGI:3589858|PMID:15944273)		 RGD PMID:15944273 PMID:11573960 MGI:3589858, RGD:633067 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 IDA IgE production after infection RGD PMID:11573960 RGD:633067 NCBI chr  X:115,348,822...115,408,682
Ensembl chr  X:115,348,860...115,408,681
Ensembl chr11:115,348,860...115,408,681 		JBrowse link
G Il2 interleukin 2 acts_upstream_of
acts_upstream_of_or_within		 ISO UniProtKB:P22301 (PMID:22962438)
MGI:1857191 (MGI:87443|PMID:1830926)		 RGD PMID:1830926 PMID:22962438 MGI:87443 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il21 interleukin 21 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5450752|PMID:23045607)		 UniProt
RGD		 PMID:23045607 GO_REF:0000024 MGI:5450752 NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996 		JBrowse link
G Il33 interleukin 33 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P08226 (MGI:3775141|PMID:18268038)		 Ensembl
RGD		 PMID:18268038 GO_REF:0000107 MGI:3775141 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO MGI:1857195|MGI:96541 (MGI:3589858|PMID:15944273) RGD PMID:15944273 MGI:3589858 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO MGI:1861951 (MGI:3589858|PMID:15944273) RGD PMID:15944273 MGI:3589858 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980 		JBrowse link
G Il5 interleukin 5 involved_in ISO UniProtKB:Q8BVZ5 (MGI:3775141|PMID:18268038) RGD PMID:18268038 MGI:3775141 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Il6 interleukin 6 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5450752|PMID:23045607)
(PMID:3491322)		 UniProt
RGD		 PMID:3491322 PMID:23045607 GO_REF:0000024 MGI:5450752 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mzb1 marginal zone B and B1 cell-specific protein involved_in ISS
ISO		 GO_REF:0000024
(MGI:4366098|PMID:19805154), (MGI:4421284|PMID:19805157)		 UniProt
RGD		 PMID:19805154 PMID:19805157 GO_REF:0000024 MGI:4366098 MGI:4421284 NCBI chr18:27,238,999...27,241,060
Ensembl chr18:27,239,001...27,241,094 		JBrowse link
G Phb1 prohibitin 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5461234|PMID:23241883)		 UniProt
RGD		 PMID:23241883 GO_REF:0000024 MGI:5461234 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Phb2 prohibitin 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5461234|PMID:23241883)		 UniProt
Ensembl
RGD		 PMID:23241883 GO_REF:0000024 GO_REF:0000107 MGI:5461234 NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISO (PMID:1793833) RGD PMID:1793833 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Rbp4 retinol binding protein 4 involved_in ISO (MGI:3796317|PMID:10944490) RGD PMID:10944490 MGI:3796317 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:25631937) RGD PMID:25631937 NCBI chr20:4,870,939...4,910,183 JBrowse link
G Sash3 SAM and SH3 domain containing 3 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:3716944 (MGI:3607020|PMID:16227612)
PMID:21873635		 RGD PMID:16227612 PMID:21873635 MGI:3607020, RGD:13792537 NCBI chr  X:127,326,815...127,341,521
Ensembl chr  X:127,326,859...127,341,519 		JBrowse link
G Stx4 syntaxin 4 involved_in ISO (PMID:24055037) RGD PMID:24055037 NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO (PMID:23857366) RGD PMID:23857366 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 involved_in ISO (MGI:74350|PMID:7749983) RGD PMID:7749983 MGI:74350 NCBI chr 5:166,606,909...166,609,599
Ensembl chr 5:166,606,909...166,609,599 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:74350|PMID:7749983) RGD PMID:7749983 MGI:74350 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
G Vamp3 vesicle-associated membrane protein 3 NOT|involved_in ISO (PMID:24055037) RGD PMID:24055037 NCBI chr 5:161,498,109...161,508,704
Ensembl chr 5:161,498,109...161,508,751 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5605956|PMID:12612580)
(PMID:11460154)		 UniProt
Ensembl
RGD		 PMID:11460154 PMID:12612580 GO_REF:0000024 GO_REF:0000107 MGI:5605956 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
positive regulation of immunoglobulin production in mucosal tissue term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C10h17orf99 smilar to human chromosome 17 open reading frame 99 involved_in ISO (MGI:6103709|PMID:28978694) RGD PMID:28978694 MGI:6103709 NCBI chr10:103,015,371...103,027,407
Ensembl chr10:103,016,505...103,027,407 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5009207|PMID:9973465)		 Ensembl
RGD		 PMID:9973465 GO_REF:0000107 MGI:5009207 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3763508|PMID:12496423) RGD PMID:12496423 MGI:3763508 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exosc3 exosome component 3 acts_upstream_of_or_within ISO (MGI:5009766|PMID:21255825) RGD PMID:21255825 MGI:5009766 NCBI chr 5:59,573,849...59,579,065
Ensembl chr 5:59,573,886...59,579,060 		JBrowse link
G Exosc6 exosome component 6 acts_upstream_of_or_within ISO (MGI:5009766|PMID:21255825) RGD PMID:21255825 MGI:5009766 NCBI chr19:39,022,171...39,023,585
Ensembl chr19:39,022,183...39,023,515 		JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in ISS
ISO		 GO_REF:0000024
(MGI:6393148|PMID:31806351)		 UniProt
RGD		 PMID:31806351 GO_REF:0000024 MGI:6393148 NCBI chr 4:120,392,812...120,415,616
Ensembl chr 4:120,366,542...120,415,616 		JBrowse link
G Kmt5b lysine methyltransferase 5B involved_in ISS
ISO		 GO_REF:0000024
(MGI:6370097|PMID:28114273)		 UniProt
RGD		 PMID:28114273 GO_REF:0000024 MGI:6370097 NCBI chr 1:201,000,444...201,049,819
Ensembl chr 1:201,000,444...201,049,819 		JBrowse link
G Kmt5c lysine methyltransferase 5C involved_in ISO
ISS		 (MGI:6370097|PMID:28114273)
GO_REF:0000024		 RGD
UniProt		 PMID:28114273 GO_REF:0000024 MGI:6370097 NCBI chr 1:69,099,531...69,107,145
Ensembl chr 1:69,099,539...69,107,145 		JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 5:158,563,545...158,576,698
Ensembl chr 5:158,563,567...158,576,693 		JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (MGI:4821506|PMID:20671152) RGD PMID:20671152 MGI:4821506 NCBI chr 4:7,525,132...7,576,659
Ensembl chr 4:7,525,004...7,576,548 		JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (MGI:5468036|PMID:23306439), (MGI:5476381|PMID:23333305), (MGI:5490831|PMID:23333306) RGD PMID:23306439 PMID:23333305 PMID:23333306 MGI:5468036 MGI:5476381 MGI:5490831 NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617 		JBrowse link
G Shld1 shieldin complex subunit 1 involved_in ISO
IBA		 (PMID:29656893)
PMID:21873635		 RGD PMID:29656893 PMID:21873635 RGD:13792537 NCBI chr 3:119,938,695...120,011,068
Ensembl chr 3:119,938,833...120,009,550 		JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr16:9,544,940...9,640,323
Ensembl chr16:9,548,660...9,639,965 		JBrowse link
G Shld3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 2:35,297,255...35,302,071
Ensembl chr 2:35,295,859...35,302,346 		JBrowse link
G Tfrc transferrin receptor involved_in ISS
ISO		 GO_REF:0000024
(PMID:26642240)		 UniProt
RGD		 PMID:26642240 GO_REF:0000024 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in ISO (PMID:23345425), (PMID:23760478)
(MGI:3041657|PMID:15077110), (MGI:3046005|PMID:15159415)		 RGD PMID:15077110 PMID:15159415 PMID:23345425 PMID:23760478 MGI:3041657 MGI:3046005 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822 		JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:1342394|PMID:10430621)		 Ensembl
RGD		 PMID:10430621 GO_REF:0000107 MGI:1342394 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Msh2 mutS homolog 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:1342394|PMID:10430621)		 Ensembl
RGD		 PMID:10430621 GO_REF:0000107 MGI:1342394 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within ISO (MGI:5462481|PMID:23241889) RGD PMID:23241889 MGI:5462481 NCBI chr14:76,833,179...76,911,304
Ensembl chr14:76,835,637...76,913,641 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO UniProtKB:Q9JK91 (MGI:1342394|PMID:10430621) RGD PMID:10430621 MGI:1342394 NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:14988498)		 AgBase
RGD		 PMID:14988498 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnfsf13 TNF superfamily member 13 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:14988498)
MGI:3038886 (MGI:3037416|PMID:14988498)		 RGD PMID:14988498 PMID:21873635 MGI:3037416, RGD:13792537 NCBI chr10:54,400,054...54,403,723
Ensembl chr10:54,400,065...54,403,042 		JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcf1 cardiotrophin-like cytokine factor 1 involved_in ISO (MGI:3777853|PMID:12023368) RGD PMID:12023368 MGI:3777853 NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605 		JBrowse link
G Il4 interleukin 4 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:3037416|PMID:14988498)		 RGD PMID:14988498 PMID:21873635 MGI:3037416, RGD:13792537 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within ISO MGI:107187 (MGI:1345885|PMID:10490661) RGD PMID:10490661 MGI:1345885 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495 		JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within ISO MGI:4127920 (MGI:5763555|PMID:25404367) RGD PMID:25404367 MGI:5763555 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845 		JBrowse link
G Cd28 Cd28 molecule acts_upstream_of_or_within ISO MGI:1857150 (MGI:62368|PMID:7688139) RGD PMID:7688139 MGI:62368 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685 		JBrowse link
G Cd40 CD40 molecule involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:2670820|PMID:12882831)		 RGD PMID:12882831 PMID:21873635 MGI:2670820, RGD:13792537 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (MGI:2670820|PMID:12882831) RGD PMID:12882831 MGI:2670820 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO MGI:1857191 (MGI:87443|PMID:1830926) RGD PMID:1830926 MGI:87443 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il4 interleukin 4 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:2670820|PMID:12882831), (MGI:3037416|PMID:14988498)		 RGD PMID:12882831 PMID:14988498 PMID:21873635 MGI:2670820 MGI:3037416, RGD:13792537 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Mlh1 mutL homolog 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:1342394|PMID:10430621)		 Ensembl
RGD		 PMID:10430621 GO_REF:0000107 MGI:1342394 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Msh2 mutS homolog 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:1342394|PMID:10430621)		 Ensembl
RGD		 PMID:10430621 GO_REF:0000107 MGI:1342394 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Pagr1 Paxip1-associated glutamate-rich protein 1 involved_in ISO (MGI:5752090|PMID:26744420) RGD PMID:26744420 MGI:5752090 NCBI chr 1:181,622,698...181,625,024 JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (MGI:5752090|PMID:26744420) RGD PMID:26744420 MGI:5752090 NCBI chr 4:7,525,132...7,576,659
Ensembl chr 4:7,525,004...7,576,548 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO UniProtKB:Q9JK91 (MGI:1342394|PMID:10430621) RGD PMID:10430621 MGI:1342394 NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:2181288 (MGI:85031|PMID:9015183) RGD PMID:9015183 MGI:85031 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Tbx21 T-box transcription factor 21 acts_upstream_of_or_within ISO MGI:2180194 (MGI:2670820|PMID:12882831) RGD PMID:12882831 MGI:2670820 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831 		JBrowse link
positive regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card9 caspase recruitment domain family, member 9 acts_upstream_of_or_within ISO MGI:3698412 (MGI:3697751|PMID:17187069) RGD PMID:17187069 MGI:3697751 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Casp1 caspase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3796019|PMID:18490713)
GO_REF:0000107		 RGD
Ensembl		 PMID:18490713 GO_REF:0000107 MGI:3796019 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp4 caspase 4 acts_upstream_of_or_within ISO MGI:1931465|MGI:2653833 (MGI:5468674|PMID:22002608) RGD PMID:22002608 MGI:5468674 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Cd36 CD36 molecule acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2447190|MGI:3573941 (MGI:3528769|PMID:15690042), (MGI:3587138|PMID:16061696)
GO_REF:0000107		 RGD
Ensembl		 PMID:15690042 PMID:16061696 GO_REF:0000107 MGI:3528769 MGI:3587138 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd74 CD74 molecule involved_in IBA
ISO
ISS		 PMID:21873635
(MGI:4943655|PMID:19413900)
GO_REF:0000024		 RGD
BHF-UCL		 PMID:19413900 PMID:21873635 GO_REF:0000024 MGI:4943655, RGD:13792537 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Gprc5b G protein-coupled receptor, class C, group 5, member B involved_in ISO (MGI:5545939|PMID:23169819) RGD PMID:23169819 MGI:5545939 NCBI chr 1:173,316,904...173,340,933
Ensembl chr 1:173,316,907...173,340,932 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (MGI:3653161|PMID:9348310) RGD PMID:9348310 MGI:3653161 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:6391873|PMID:22733818) RGD PMID:22733818 MGI:6391873 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 acts_upstream_of_or_within ISO (MGI:5532755|PMID:24020373) RGD PMID:24020373 MGI:5532755 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457 		JBrowse link
G Mir324 microRNA 324 acts_upstream_of_or_within ISO (MGI:5576401|PMID:24882011) RGD PMID:24882011 MGI:5576401 NCBI chr10:54,734,680...54,734,762
Ensembl chr10:54,734,678...54,734,766 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of_or_within ISO MGI:2147032|MGI:2385681 (MGI:2670551|PMID:12872135), (MGI:3619313|PMID:11067888), (MGI:3640248|PMID:10607756) RGD PMID:10607756 PMID:11067888 PMID:12872135 MGI:2670551 MGI:3619313 MGI:3640248 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of_or_within ISO MGI:2429397|MGI:2674231 (MGI:3775161|PMID:18261938) RGD PMID:18261938 MGI:3775161 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:1341839|MGI:2680581|MGI:3529594 (MGI:2679172|PMID:14560001), (MGI:3050756|PMID:15220916), (MGI:3528786|PMID:15692051), (MGI:3775161|PMID:18261938) RGD PMID:14560001 PMID:15220916 PMID:15692051 PMID:18261938 MGI:2679172 MGI:3050756 MGI:3528786 MGI:3775161 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:2386080|MGI:3606250 (MGI:1929334|PMID:11016935), (MGI:3796019|PMID:18490713) RGD PMID:11016935 PMID:18490713 MGI:1929334 MGI:3796019 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Panx1 Pannexin 1 acts_upstream_of_or_within ISO (MGI:3796019|PMID:18490713) RGD PMID:18490713 MGI:3796019 NCBI chr 8:11,851,176...11,889,774
Ensembl chr 8:11,850,730...11,889,774 		JBrowse link
G Plcg2 phospholipase C, gamma 2 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:5300086|PMID:22041900)
GO_REF:0000107		 RGD
Ensembl		 PMID:22041900 GO_REF:0000107 MGI:5300086 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Pycard PYD and CARD domain containing acts_upstream_of_or_within ISO MGI:107700|MGI:2653833 (MGI:5468674|PMID:22002608) RGD PMID:22002608 MGI:5468674 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO MGI:2660793 (MGI:2176422|PMID:11894098), (MGI:3775161|PMID:18261938) RGD PMID:11894098 PMID:18261938 MGI:2176422 MGI:3775161 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:19304799) RGD PMID:19304799 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
G Rtn4 reticulon 4 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4366092|PMID:19805174)		 UniProt
RGD		 PMID:19805174 GO_REF:0000024 MGI:4366092 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686 		JBrowse link
G Sema7a semaphorin 7A (John Milton Hagen blood group) involved_in IBA
ISO		 PMID:21873635
(MGI:3710037|PMID:17377534)		 RGD PMID:17377534 PMID:21873635 MGI:3710037, RGD:13792537 NCBI chr 8:58,348,448...58,370,536
Ensembl chr 8:58,348,448...58,370,536 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA		 (MGI:5319292|PMID:22315447)
GO_REF:0000107		 RGD
Ensembl		 PMID:22315447 GO_REF:0000107 MGI:5319292 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Spon2 spondin 2 acts_upstream_of_or_within ISO MGI:3026870 (MGI:2686801|PMID:14691481) RGD PMID:14691481 MGI:2686801 NCBI chr14:77,505,695...77,518,001
Ensembl chr14:77,511,901...77,517,996 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO MGI:108005|MGI:2679794|MGI:3029019 (MGI:2669022|PMID:12855817), (MGI:2670551|PMID:12872135) RGD PMID:12855817 PMID:12872135 MGI:2669022 MGI:2670551 NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Tirap TIR domain containing adaptor protein acts_upstream_of_or_within ISO MGI:3573942 (MGI:3528769|PMID:15690042) RGD PMID:15690042 MGI:3528769 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO MGI:2178675|MGI:2674036 (MGI:2178646|PMID:10549626), (MGI:3528769|PMID:15690042), (MGI:3619313|PMID:11067888), (MGI:3775161|PMID:18261938) RGD PMID:10549626 PMID:11067888 PMID:15690042 PMID:18261938 MGI:2178646 MGI:3528769 MGI:3619313 MGI:3775161 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr3 toll-like receptor 3 acts_upstream_of_or_within ISO MGI:3690535 (MGI:2669022|PMID:12855817), (MGI:3775161|PMID:18261938) RGD PMID:12855817 PMID:18261938 MGI:2669022 MGI:3775161 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857718|MGI:1860755|MGI:1860885 (MGI:1351361|PMID:10623794), (MGI:2178646|PMID:10549626), (MGI:2686801|PMID:14691481), (MGI:3530402|PMID:15661922), (MGI:3640248|PMID:10607756), (MGI:3775161|PMID:18261938), (MGI:5013871|PMID:21609717)		 Ensembl
RGD		 PMID:10549626 PMID:10607756 PMID:10623794 PMID:14691481 PMID:15661922 More... GO_REF:0000107 MGI:1351361 MGI:2178646 MGI:2686801 MGI:3530402 MGI:3640248 MGI:3775161 MGI:5013871 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr7 toll-like receptor 7 acts_upstream_of_or_within ISO (MGI:3775161|PMID:18261938) RGD PMID:18261938 MGI:3775161 NCBI chr  X:27,027,380...27,054,309
Ensembl chr  X:27,027,425...27,054,754 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO
IEA		 (PMID:18174455)
GO_REF:0000107		 RGD
Ensembl		 PMID:18174455 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
positive regulation of mast cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1a Fc epsilon receptor Ia acts_upstream_of_or_within ISO (MGI:85068|PMID:9000133) RGD PMID:9000133 MGI:85068 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351 		JBrowse link
G Fcer1g Fc epsilon receptor Ig acts_upstream_of_or_within ISO MGI:2384004 (MGI:3029067|PMID:14764707) RGD PMID:14764707 MGI:3029067 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO (PMID:20100931) RGD PMID:20100931 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5586645|PMID:24586680)		 UniProt
RGD		 PMID:24586680 GO_REF:0000024 MGI:5586645 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2384078 (MGI:85068|PMID:9000133)
GO_REF:0000107		 RGD
Ensembl		 PMID:9000133 GO_REF:0000107 MGI:85068 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
positive regulation of myeloid dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk4 calcium/calmodulin-dependent protein kinase IV NOT|involved_in ISO (PMID:17909078) RGD PMID:17909078 NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487 		JBrowse link
G Ddx1 DEAD-box helicase 1 involved_in ISO (MGI:5050760|PMID:21703541) RGD PMID:21703541 MGI:5050760 NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365 		JBrowse link
G Ddx21 DExD-box helicase 21 involved_in ISO (MGI:5050760|PMID:21703541) RGD PMID:21703541 MGI:5050760 NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543 		JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO (MGI:5050760|PMID:21703541) RGD PMID:21703541 MGI:5050760 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISS
ISO		 GO_REF:0000024
(MGI:5050760|PMID:21703541)		 UniProt
RGD		 PMID:21703541 GO_REF:0000024 MGI:5050760 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Rig1 RNA sensor RIG-1 involved_in ISO (MGI:5050760|PMID:21703541) RGD PMID:21703541 MGI:5050760 NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 involved_in ISO (MGI:5050760|PMID:21703541) RGD PMID:21703541 MGI:5050760 NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462 		JBrowse link
positive regulation of myeloid leukocyte cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mif macrophage migration inhibitory factor involved_in ISO (MGI:2156302|PMID:11756671) RGD PMID:11756671 MGI:2156302 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
positive regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd160 CD160 molecule involved_in ISO (PMID:17307798) RGD PMID:17307798 NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834 		JBrowse link
G Cd226 CD226 molecule involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:4454325 (MGI:5569209|PMID:24658051)		 RGD PMID:24658051 PMID:21873635 MGI:5569209, RGD:13792537 NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051 		JBrowse link
G Clnk cytokine-dependent hematopoietic cell linker involved_in ISO (MGI:3774350|PMID:16439675) RGD PMID:16439675 MGI:3774350 NCBI chr14:71,923,894...72,101,180
Ensembl chr14:71,873,105...72,101,208 		JBrowse link
G Gimap5 GTPase, IMAP family member 5 IMP RGD PMID:15100275 RGD:2303778 NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086 		JBrowse link
G Il21 interleukin 21 acts_upstream_of_or_within ISO (MGI:3028812|PMID:14764669) RGD PMID:14764669 MGI:3028812 NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:30134159) RGD PMID:30134159 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:27455421) RGD PMID:27455421 NCBI chr20:3,403,418...3,479,476 JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:16366734), (PMID:19304799), (PMID:23184984) RGD PMID:16366734 PMID:19304799 PMID:23184984 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
positive regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2 microglobulin involved_in ISO
IEA		 (PMID:24643698)
GO_REF:0000107		 RGD
Ensembl		 PMID:24643698 GO_REF:0000107 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:16818763) RGD PMID:16818763 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831 		JBrowse link
G Fzd5 frizzled class receptor 5 involved_in ISO
IEA		 (PMID:16601243)
GO_REF:0000107		 RGD
Ensembl		 PMID:16601243 GO_REF:0000107 NCBI chr 9:66,113,096...66,120,276
Ensembl chr 9:66,113,112...66,121,457 		JBrowse link
G Malt1 MALT1 paracaspase involved_in ISO (PMID:15125833) RGD PMID:15125833 NCBI chr18:58,942,282...58,996,318
Ensembl chr18:58,942,299...58,994,260 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in ISO (PMID:15125833) RGD PMID:15125833 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G RT1-CE16 RT1 class I, locus CE16 involved_in ISO (PMID:24643698) RGD PMID:24643698 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
G Sash3 SAM and SH3 domain containing 3 acts_upstream_of_or_within ISO MGI:3716944 (MGI:3607020|PMID:16227612) RGD PMID:16227612 MGI:3607020 NCBI chr  X:127,326,815...127,341,521
Ensembl chr  X:127,326,859...127,341,519 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4942267|PMID:9670042), (MGI:4943387|PMID:18354165) RGD PMID:9670042 PMID:18354165 MGI:4942267 MGI:4943387 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in ISO (PMID:15125833) RGD PMID:15125833 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO
IEA		 (PMID:15125833)
GO_REF:0000107		 RGD
Ensembl		 PMID:15125833 GO_REF:0000107 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (MGI:85636|PMID:9029087) RGD PMID:9029087 MGI:85636 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
positive regulation of T-helper 1 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid5a AT-rich interaction domain 5A involved_in ISO (MGI:5887181|PMID:27671645) RGD PMID:27671645 MGI:5887181 NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597 		JBrowse link
G Il18 interleukin 18 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:10653850)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:10653850 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il18r1 interleukin 18 receptor 1 involved_in ISO (PMID:10653850) RGD PMID:10653850 NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO
ISS		 (PMID:10653850)
GO_REF:0000024		 RGD
UniProt		 PMID:10653850 GO_REF:0000024 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 involved_in ISO
ISS		 (PMID:10653850)
GO_REF:0000024		 RGD
UniProt		 PMID:10653850 GO_REF:0000024 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937 		JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (MGI:5700493|PMID:9126961) RGD PMID:9126961 MGI:5700493 NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:1354779|PMID:10761931) RGD PMID:10761931 MGI:1354779 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5009207|PMID:9973465)		 Ensembl
RGD		 PMID:9973465 GO_REF:0000107 MGI:5009207 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
positive regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 Cd81 molecule involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:8766544)
(MGI:1926561|PMID:11046035)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:8766544 PMID:11046035 GO_REF:0000024 GO_REF:0000107 MGI:1926561 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660 		JBrowse link
G Dennd1b DENN domain containing 1B involved_in ISO (PMID:26774822)
(MGI:5751612|PMID:26774822)		 RGD PMID:26774822 MGI:5751612 NCBI chr13:50,545,324...50,772,922
Ensembl chr13:50,545,836...50,770,601 		JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO (MGI:3046385|PMID:15087456) RGD PMID:15087456 MGI:3046385 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Il4 interleukin 4 involved_in ISO (PMID:20554961) RGD PMID:20554961 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 involved_in ISO (MGI:5795829|PMID:11159963) RGD PMID:11159963 MGI:5795829 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in ISO (MGI:5689221|PMID:26098997) RGD PMID:26098997 MGI:5689221 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Prkcz protein kinase C, zeta involved_in ISS
ISO		 GO_REF:0000024
(MGI:3584076|PMID:15987782)		 UniProt
RGD		 PMID:15987782 GO_REF:0000024 MGI:3584076 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:3844206|PMID:19047684)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19047684 GO_REF:0000024 GO_REF:0000107 MGI:3844206 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5009207|PMID:9973465)		 Ensembl
RGD		 PMID:9973465 GO_REF:0000107 MGI:5009207 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Evpl envoplakin acts_upstream_of_or_within ISO MGI:1194898|MGI:96626 (MGI:6507238|PMID:27427436) RGD PMID:27427436 MGI:6507238 NCBI chr10:101,458,227...101,474,778
Ensembl chr10:101,458,216...101,474,763 		JBrowse link
G Ivl involucrin acts_upstream_of_or_within ISO MGI:107507|MGI:1194898 (MGI:6507238|PMID:27427436) RGD PMID:27427436 MGI:6507238 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100 		JBrowse link
G Ppl periplakin acts_upstream_of_or_within ISO MGI:107507|MGI:96626 (MGI:6507238|PMID:27427436) RGD PMID:27427436 MGI:6507238 NCBI chr10:10,450,919...10,496,575
Ensembl chr10:10,450,919...10,496,575 		JBrowse link
regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg5 autophagy related 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:5435097|PMID:22710871)		 Ensembl
RGD		 PMID:22710871 GO_REF:0000107 MGI:5435097 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO UniProtKB:Q9Z0D9 (MGI:5888814|PMID:28052249) RGD PMID:28052249 MGI:5888814 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Tril TLR4 interactor with leucine-rich repeats involved_in ISO
IBA		 (PMID:19710467)
PMID:21873635		 RGD PMID:19710467 PMID:21873635 RGD:13792537 NCBI chr 4:82,922,327...82,927,172
Ensembl chr 4:82,922,328...82,927,172 		JBrowse link
regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO (MGI:3828894|PMID:19047410) RGD PMID:19047410 MGI:3828894 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr3 toll-like receptor 3 acts_upstream_of_or_within ISO (MGI:3828894|PMID:19047410) RGD PMID:19047410 MGI:3828894 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3828894|PMID:19047410)		 Ensembl
RGD		 PMID:19047410 GO_REF:0000107 MGI:3828894 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr9 toll-like receptor 9 acts_upstream_of_or_within ISO (MGI:3828894|PMID:19047410) RGD PMID:19047410 MGI:3828894 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
regulation of immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40 CD40 molecule acts_upstream_of_or_within ISO (MGI:2680840|PMID:12958312) RGD PMID:12958312 MGI:2680840 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cd40lg CD40 ligand involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:2680840|PMID:12958312)		 Ensembl
RGD		 PMID:12958312 GO_REF:0000107 MGI:2680840 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Cgas cyclic GMP-AMP synthase acts_upstream_of_or_within ISO MGI:1328317 (MGI:5699498|PMID:26371324) RGD PMID:26371324 MGI:5699498 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO MGI:3696705 (MGI:3695768|PMID:16275384) RGD PMID:16275384 MGI:3695768 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Pkn1 protein kinase N1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:5475202 (MGI:5467878|PMID:23223530)
GO_REF:0000107		 RGD
Ensembl		 PMID:23223530 GO_REF:0000107 MGI:5467878 NCBI chr19:24,442,130...24,470,107
Ensembl chr19:24,442,122...24,470,107 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (MGI:2680840|PMID:12958312) RGD PMID:12958312 MGI:2680840 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 acts_upstream_of_or_within ISO (MGI:2680840|PMID:12958312) RGD PMID:12958312 MGI:2680840 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Traf6 TNF receptor associated factor 6 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2680840|PMID:12958312)
GO_REF:0000107		 RGD
Ensembl		 PMID:12958312 GO_REF:0000107 MGI:2680840 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:2442261 (MGI:5699498|PMID:26371324), (MGI:5787754|PMID:26320659) RGD PMID:26320659 PMID:26371324 MGI:5699498 MGI:5787754 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplf aprataxin and PNKP like factor acts_upstream_of_or_within ISO MGI:4128102 (MGI:4887518|PMID:21211721) RGD PMID:21211721 MGI:4887518 NCBI chr 4:120,070,471...120,122,656
Ensembl chr 4:120,070,471...120,122,633 		JBrowse link
G Mir181b1 microRNA 181b-1 acts_upstream_of_or_within ISO (MGI:3817382|PMID:18762567) RGD PMID:18762567 MGI:3817382 NCBI chr13:49,485,688...49,485,797
Ensembl chr13:49,485,688...49,485,797 		JBrowse link
G Mir181b2 microRNA 181b-2 acts_upstream_of_or_within ISO (MGI:3817382|PMID:18762567) RGD PMID:18762567 MGI:3817382 NCBI chr 3:22,616,948...22,617,035
Ensembl chr 3:22,616,948...22,617,035 		JBrowse link
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor involved_in ISO (MGI:5004983|PMID:21518874) RGD PMID:21518874 MGI:5004983 NCBI chr10:63,103,920...63,140,780
Ensembl chr10:63,103,921...63,140,780 		JBrowse link
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO MGI:3696705 (MGI:3695768|PMID:16275384) RGD PMID:16275384 MGI:3695768 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Il27ra interleukin 27 receptor subunit alpha acts_upstream_of_or_within ISO MGI:3525439 (MGI:1926579|PMID:11057672) RGD PMID:11057672 MGI:1926579 NCBI chr19:24,109,963...24,121,977
Ensembl chr19:24,109,972...24,121,938 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3695433 (MGI:3694584|PMID:17137798)
GO_REF:0000107		 RGD
Ensembl		 PMID:17137798 GO_REF:0000107 MGI:3694584 NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5649169|PMID:25310967)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:25310967 GO_REF:0000024 GO_REF:0000107 MGI:5649169 NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Litaf lipopolysaccharide-induced TNF factor acts_upstream_of_or_within ISO MGI:3687962 (MGI:3687609|PMID:16954198) RGD PMID:16954198 MGI:3687609 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763 		JBrowse link
G Ube2j1 ubiquitin-conjugating enzyme E2, J1 acts_upstream_of_or_within ISO MGI:109298 (MGI:5532755|PMID:24020373) RGD PMID:24020373 MGI:5532755 NCBI chr 5:47,422,476...47,441,476
Ensembl chr 5:47,422,587...47,441,461 		JBrowse link
regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl20 C-C motif chemokine ligand 20 NOT|involved_in ISO (MGI:3820359|PMID:19050256) RGD PMID:19050256 MGI:3820359 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5926947|PMID:28507030)		 UniProt
RGD		 PMID:28507030 GO_REF:0000024 MGI:5926947 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in IBA
ISO		 PMID:21873635
(MGI:5888814|PMID:28052249)		 RGD PMID:28052249 PMID:21873635 MGI:5888814, RGD:13792537 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 involved_in ISO
IEA
ISS		 (PMID:20656926)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20656926 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    immune system process 2664
      production of molecular mediator of immune response 245
        regulation of production of molecular mediator of immune response 212
          negative regulation of production of molecular mediator of immune response + 49
          positive regulation of production of molecular mediator of immune response + 150
          regulation of antimicrobial peptide production + 11
          regulation of cytokine production involved in immune response + 130
          regulation of granzyme A production + 1
          regulation of granzyme B production + 3
          regulation of immunoglobulin production + 88
Path 2
Term Annotations click to browse term
  biological_process 19553
    biological regulation 13187
      regulation of biological process 12813
        regulation of metabolic process 6364
          regulation of biosynthetic process 5241
            regulation of cellular biosynthetic process 5196
              regulation of macromolecule biosynthetic process 5050
                regulation of gene expression 4936
                  regulation of production of molecular mediator of immune response 212
                    negative regulation of production of molecular mediator of immune response + 49
                    positive regulation of production of molecular mediator of immune response + 150
                    regulation of antimicrobial peptide production + 11
                    regulation of cytokine production involved in immune response + 130
                    regulation of granzyme A production + 1
                    regulation of granzyme B production + 3
                    regulation of immunoglobulin production + 88
paths to the root