|
G |
AARS2 |
alanyl-tRNA synthetase 2, mitochondrial |
increases expression |
EXP |
butylparaben results in increased expression of AARS2 mRNA |
CTD |
PMID:17121429 |
|
NCBI chr 6:44,298,731...44,313,347
Ensembl chr 6:44,298,731...44,313,347
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|
G |
ABAT |
4-aminobutyrate aminotransferase |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of ABAT mRNA |
CTD |
PMID:25607892 |
|
NCBI chr16:8,674,617...8,784,570
Ensembl chr16:8,674,596...8,784,575
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|
G |
ACAN |
aggrecan |
decreases expression |
ISO |
butylparaben results in decreased expression of ACAN mRNA |
CTD |
PMID:28527915 |
|
NCBI chr15:88,803,436...88,875,353
Ensembl chr15:88,803,436...88,875,353
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|
G |
ACSL6 |
acyl-CoA synthetase long chain family member 6 |
increases expression |
EXP |
butylparaben results in increased expression of ACSL6 mRNA |
CTD |
PMID:17121429 |
|
NCBI chr 5:131,949,973...132,012,213
Ensembl chr 5:131,949,973...132,012,243
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|
G |
ACTN1 |
actinin alpha 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of ACTN1 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr14:68,874,128...68,979,302
Ensembl chr14:68,874,128...68,979,440
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|
G |
ADAM17 |
ADAM metallopeptidase domain 17 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of ADAM17 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of ADAM17 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732
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|
G |
ADIPOQ |
adiponectin, C1Q and collagen domain containing |
multiple interactions increases expression |
EXP ISO |
butylparaben promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein] butylparaben results in increased expression of ADIPOQ mRNA 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [butylparaben results in increased expression of ADIPOQ mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [butylparaben results in increased expression of ADIPOQ mRNA]; butylparaben promotes the reaction [Dexamethasone results in increased expression of ADIPOQ mRNA]; Mifepristone inhibits the reaction [butylparaben results in increased expression of ADIPOQ mRNA] |
CTD |
PMID:22956630 PMID:31016361 |
|
NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
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|
G |
ADM |
adrenomedullin |
decreases expression |
EXP |
butylparaben results in decreased expression of ADM mRNA |
CTD |
PMID:17121429 |
|
NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397
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|
G |
ALPL |
alkaline phosphatase, biomineralization associated |
decreases expression multiple interactions |
ISO |
butylparaben results in decreased expression of ALPL mRNA NR3C1 protein promotes the reaction [butylparaben results in decreased expression of ALPL mRNA]; PPARG protein promotes the reaction [butylparaben results in decreased expression of ALPL mRNA] |
CTD |
PMID:28527915 |
|
NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410
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|
G |
AR |
androgen receptor |
affects binding affects expression decreases expression |
ISO |
butylparaben binds to AR protein butylparaben affects the expression of AR protein butylparaben results in decreased expression of AR mRNA; butylparaben results in decreased expression of AR protein |
CTD |
PMID:20371976 PMID:26888303 PMID:27444704 |
|
NCBI chr X:67,544,021...67,730,619
Ensembl chr X:67,544,021...67,730,619
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|
G |
ARHGAP9 |
Rho GTPase activating protein 9 |
increases expression |
EXP |
butylparaben results in increased expression of ARHGAP9 mRNA |
CTD |
PMID:17121429 |
|
NCBI chr12:57,472,269...57,488,824
Ensembl chr12:57,472,264...57,488,814
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G |
ATF4 |
activating transcription factor 4 |
increases expression |
ISO |
butylparaben results in increased expression of ATF4 mRNA |
CTD |
PMID:36277366 |
|
NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683
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G |
ATF6 |
activating transcription factor 6 |
increases expression |
EXP |
butylparaben results in increased expression of ATF6 protein |
CTD |
PMID:29319206 |
|
NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574
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G |
ATM |
ATM serine/threonine kinase |
affects expression |
EXP |
butylparaben affects the expression of ATM mRNA |
CTD |
PMID:24481588 |
|
NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,823...108,369,102
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|
G |
ATP5MG |
ATP synthase membrane subunit g |
increases expression |
EXP |
butylparaben results in increased expression of ATP5MG mRNA |
CTD |
PMID:17121429 |
|
NCBI chr11:118,401,606...118,409,847
Ensembl chr11:118,401,346...118,433,278
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G |
ATR |
ATR serine/threonine kinase |
increases expression |
EXP |
butylparaben results in increased expression of ATR mRNA |
CTD |
PMID:24481588 |
|
NCBI chr 3:142,449,235...142,578,733
Ensembl chr 3:142,449,007...142,578,733
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G |
AVP |
arginine vasopressin |
multiple interactions |
ISO |
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of AVP mRNA |
CTD |
PMID:34383603 |
|
NCBI chr20:3,082,556...3,084,724
Ensembl chr20:3,082,556...3,084,724
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G |
BCL2L1 |
BCL2 like 1 |
increases expression |
EXP |
butylparaben results in increased expression of BCL2L1 mRNA; butylparaben results in increased expression of BCL2L1 protein |
CTD |
PMID:24481588 |
|
NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
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G |
BDNF |
brain derived neurotrophic factor |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of BDNF mRNA |
CTD |
PMID:25607892 |
|
NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
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G |
BGLAP |
bone gamma-carboxyglutamate protein |
decreases expression |
ISO |
butylparaben results in decreased expression of BGLAP mRNA |
CTD |
PMID:28527915 |
|
NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
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G |
BSN |
bassoon presynaptic cytomatrix protein |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of BSN mRNA |
CTD |
PMID:25607892 |
|
NCBI chr 3:49,554,477...49,673,130
Ensembl chr 3:49,554,477...49,671,549
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G |
CACNA1A |
calcium voltage-gated channel subunit alpha1 A |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNA1A mRNA |
CTD |
PMID:25607892 |
|
NCBI chr19:13,206,442...13,506,479
Ensembl chr19:13,206,442...13,633,025
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G |
CACNA1C |
calcium voltage-gated channel subunit alpha1 C |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] affects the expression of CACNA1C mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNA1C mRNA |
CTD |
PMID:25607892 |
|
NCBI chr12:1,970,780...2,697,950
Ensembl chr12:1,970,772...2,697,950
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G |
CACNA1D |
calcium voltage-gated channel subunit alpha1 D |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CACNA1D mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNA1D mRNA |
CTD |
PMID:25607892 |
|
NCBI chr 3:53,494,611...53,813,733
Ensembl chr 3:53,328,963...53,813,733
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G |
CACNA1E |
calcium voltage-gated channel subunit alpha1 E |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNA1E mRNA |
CTD |
PMID:25607892 |
|
NCBI chr 1:181,317,699...181,808,084
Ensembl chr 1:181,317,690...181,813,262
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G |
CACNA1F |
calcium voltage-gated channel subunit alpha1 F |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNA1F mRNA |
CTD |
PMID:25607892 |
|
NCBI chr X:49,205,063...49,233,340
Ensembl chr X:49,205,063...49,233,371
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G |
CACNA1G |
calcium voltage-gated channel subunit alpha1 G |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CACNA1G mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNA1G mRNA |
CTD |
PMID:25607892 |
|
NCBI chr17:50,560,715...50,627,474
Ensembl chr17:50,560,715...50,627,474
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G |
CACNA1H |
calcium voltage-gated channel subunit alpha1 H |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNA1H mRNA |
CTD |
PMID:25607892 |
|
NCBI chr16:1,153,106...1,221,768
Ensembl chr16:1,153,103...1,224,169
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G |
CACNA1I |
calcium voltage-gated channel subunit alpha1 I |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CACNA1I mRNA |
CTD |
PMID:25607892 |
|
NCBI chr22:39,570,753...39,689,735
Ensembl chr22:39,570,753...39,689,735
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G |
CACNA2D1 |
calcium voltage-gated channel auxiliary subunit alpha2delta 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CACNA2D1 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNA2D1 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr 7:81,946,444...82,443,956
Ensembl chr 7:81,946,444...82,443,956
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G |
CACNA2D2 |
calcium voltage-gated channel auxiliary subunit alpha2delta 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CACNA2D2 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNA2D2 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr 3:50,362,613...50,504,244
Ensembl chr 3:50,362,613...50,504,244
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G |
CACNA2D3 |
calcium voltage-gated channel auxiliary subunit alpha2delta 3 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] affects the expression of CACNA2D3 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNA2D3 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr 3:54,122,552...55,074,557
Ensembl chr 3:54,122,552...55,074,557
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G |
CACNB1 |
calcium voltage-gated channel auxiliary subunit beta 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNB1 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr17:39,173,453...39,197,669
Ensembl chr17:39,173,453...39,197,702
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G |
CACNB2 |
calcium voltage-gated channel auxiliary subunit beta 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CACNB2 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNB2 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr10:18,140,424...18,543,557
Ensembl chr10:18,140,424...18,543,557
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G |
CACNB3 |
calcium voltage-gated channel auxiliary subunit beta 3 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CACNB3 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNB3 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr12:48,814,480...48,828,941
Ensembl chr12:48,813,794...48,828,941
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G |
CACNG2 |
calcium voltage-gated channel auxiliary subunit gamma 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNG2 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr22:36,560,857...36,703,752
Ensembl chr22:36,560,857...36,703,752
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G |
CACNG5 |
calcium voltage-gated channel auxiliary subunit gamma 5 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNG5 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr17:66,835,117...66,894,751
Ensembl chr17:66,835,117...66,894,751
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G |
CACNG6 |
calcium voltage-gated channel auxiliary subunit gamma 6 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CACNG6 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNG6 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr19:53,991,149...54,012,666
Ensembl chr19:53,991,637...54,012,666
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G |
CACNG8 |
calcium voltage-gated channel auxiliary subunit gamma 8 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNG8 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr19:53,962,937...53,990,215
Ensembl chr19:53,962,937...53,990,215
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G |
CALB2 |
calbindin 2 |
increases expression |
EXP |
butylparaben results in increased expression of CALB2 mRNA |
CTD |
PMID:17121429 |
|
NCBI chr16:71,358,723...71,390,433
Ensembl chr16:71,358,713...71,390,436
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G |
CAMK2B |
calcium/calmodulin dependent protein kinase II beta |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CAMK2B mRNA |
CTD |
PMID:25607892 |
|
NCBI chr 7:44,217,154...44,326,013
Ensembl chr 7:44,210,019...44,334,577
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G |
CARTPT |
CART prepropeptide |
multiple interactions |
ISO |
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in increased expression of CARTPT mRNA |
CTD |
PMID:34383603 |
|
NCBI chr 5:71,719,275...71,721,045
Ensembl chr 5:71,719,275...71,721,048
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G |
CASK |
calcium/calmodulin dependent serine protein kinase |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CASK mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] affects the expression of CASK mRNA |
CTD |
PMID:25607892 |
|
NCBI chr X:41,514,934...41,923,554
Ensembl chr X:41,514,934...41,923,554
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G |
CASP8 |
caspase 8 |
increases expression |
EXP |
butylparaben results in increased expression of CASP8 protein |
CTD |
PMID:24481588 |
|
NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
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G |
CAT |
catalase |
decreases activity multiple interactions |
ISO |
butylparaben results in decreased activity of CAT protein butylparaben inhibits the reaction [Triclosan results in increased activity of CAT protein] |
CTD |
PMID:29350491 |
|
NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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G |
CCNA1 |
cyclin A1 |
increases expression |
EXP |
butylparaben results in increased expression of CCNA1 mRNA |
CTD |
PMID:24481588 |
|
NCBI chr13:36,431,517...36,442,870
Ensembl chr13:36,431,520...36,442,870
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G |
CCNA2 |
cyclin A2 |
increases expression |
EXP |
butylparaben results in increased expression of CCNA2 mRNA |
CTD |
PMID:24481588 |
|
NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883
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G |
CCNB2 |
cyclin B2 |
increases expression |
EXP |
butylparaben results in increased expression of CCNB2 mRNA |
CTD |
PMID:24481588 |
|
NCBI chr15:59,105,146...59,125,045
Ensembl chr15:59,105,126...59,125,045
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G |
CCND1 |
cyclin D1 |
increases expression |
EXP |
butylparaben results in increased expression of CCND1 mRNA |
CTD |
PMID:23524099 PMID:24481588 |
|
NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
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G |
CCND3 |
cyclin D3 |
decreases expression affects expression |
EXP |
butylparaben results in decreased expression of CCND3 mRNA butylparaben affects the expression of CCND3 mRNA |
CTD |
PMID:24481588 |
|
NCBI chr 6:41,934,933...42,050,035
Ensembl chr 6:41,934,934...42,050,357
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G |
CCNE1 |
cyclin E1 |
affects expression |
EXP |
butylparaben affects the expression of CCNE1 mRNA |
CTD |
PMID:24481588 |
|
NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312
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G |
CCNE2 |
cyclin E2 |
increases expression |
EXP |
butylparaben results in increased expression of CCNE2 mRNA |
CTD |
PMID:24481588 |
|
NCBI chr 8:94,880,224...94,896,693
Ensembl chr 8:94,879,770...94,896,678
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G |
CD44 |
CD44 molecule (IN blood group) |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CD44 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CD44 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402
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G |
CDC25A |
cell division cycle 25A |
increases expression |
EXP |
butylparaben results in increased expression of CDC25A mRNA |
CTD |
PMID:24481588 |
|
NCBI chr 3:48,157,146...48,188,417
Ensembl chr 3:48,157,146...48,188,417
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G |
CDK2 |
cyclin dependent kinase 2 |
increases expression |
EXP |
butylparaben results in increased expression of CDK2 mRNA |
CTD |
PMID:24481588 |
|
NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789
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G |
CDK4 |
cyclin dependent kinase 4 |
increases expression |
EXP |
butylparaben results in increased expression of CDK4 mRNA |
CTD |
PMID:24481588 |
|
NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013
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G |
CDK6 |
cyclin dependent kinase 6 |
affects expression |
EXP |
butylparaben affects the expression of CDK6 mRNA |
CTD |
PMID:24481588 |
|
NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,573
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G |
CDKN1A |
cyclin dependent kinase inhibitor 1A |
decreases expression |
EXP |
butylparaben results in decreased expression of CDKN1A mRNA; butylparaben results in decreased expression of CDKN1A protein |
CTD |
PMID:24481588 |
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NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
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G |
CEBPA |
CCAAT enhancer binding protein alpha |
multiple interactions increases expression |
ISO EXP |
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [butylparaben results in increased expression of CEBPA mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [butylparaben results in increased expression of CEBPA mRNA]; butylparaben promotes the reaction [Dexamethasone results in increased expression of CEBPA mRNA]; Mifepristone inhibits the reaction [butylparaben results in increased expression of CEBPA mRNA]; PPARG protein promotes the reaction [butylparaben results in increased expression of CEBPA mRNA]; Rimonabant inhibits the reaction [butylparaben results in increased expression of CEBPA mRNA] |
CTD |
PMID:22956630 PMID:27659731 PMID:28527915 |
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NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534
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G |
CELF5 |
CUGBP Elav-like family member 5 |
increases expression |
EXP |
butylparaben results in increased expression of CELF5 mRNA |
CTD |
PMID:17121429 |
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NCBI chr19:3,224,661...3,297,076
Ensembl chr19:3,224,661...3,297,076
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G |
CHRDL1 |
chordin like 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] affects the expression of CHRDL1 mRNA |
CTD |
PMID:25607892 |
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NCBI chr X:110,673,856...110,795,817
Ensembl chr X:110,673,856...110,795,819
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G |
CHST1 |
carbohydrate sulfotransferase 1 |
increases expression |
EXP |
butylparaben results in increased expression of CHST1 mRNA |
CTD |
PMID:17121429 |
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NCBI chr11:45,647,689...45,665,622
Ensembl chr11:45,647,689...45,665,622
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G |
CNTN3 |
contactin 3 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CNTN3 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 3:74,262,568...74,614,659
Ensembl chr 3:74,262,568...74,614,659
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G |
CNTN4 |
contactin 4 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CNTN4 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 3:2,098,866...3,057,959
Ensembl chr 3:2,098,813...3,057,959
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G |
COL10A1 |
collagen type X alpha 1 chain |
decreases expression |
ISO |
butylparaben results in decreased expression of COL10A1 mRNA |
CTD |
PMID:28527915 |
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NCBI chr 6:116,118,909...116,217,144
Ensembl chr 6:116,118,909...116,158,747
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G |
COL2A1 |
collagen type II alpha 1 chain |
decreases expression |
ISO |
butylparaben results in decreased expression of COL2A1 mRNA |
CTD |
PMID:28527915 |
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NCBI chr12:47,972,967...48,006,212
Ensembl chr12:47,972,967...48,004,554
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G |
COL8A1 |
collagen type VIII alpha 1 chain |
increases expression |
EXP |
butylparaben results in increased expression of COL8A1 mRNA |
CTD |
PMID:17121429 |
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NCBI chr 3:99,638,594...99,799,217
Ensembl chr 3:99,638,475...99,799,226
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G |
COPS2 |
COP9 signalosome subunit 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of COPS2 mRNA |
CTD |
PMID:25607892 |
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NCBI chr15:49,122,727...49,155,599
Ensembl chr15:49,106,068...49,155,661
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G |
CRH |
corticotropin releasing hormone |
multiple interactions |
ISO |
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] affects the expression of CRH mRNA |
CTD |
PMID:34383603 |
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NCBI chr 8:66,176,376...66,178,464
Ensembl chr 8:66,176,376...66,178,464
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G |
CXCL3 |
C-X-C motif chemokine ligand 3 |
increases expression |
EXP |
butylparaben results in increased expression of CXCL3 mRNA |
CTD |
PMID:17121429 |
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NCBI chr 4:74,036,589...74,038,689
Ensembl chr 4:74,036,589...74,038,807
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G |
CYBA |
cytochrome b-245 alpha chain |
increases expression |
EXP |
butylparaben results in increased expression of CYBA mRNA |
CTD |
PMID:17121429 |
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NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083
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G |
CYCS |
cytochrome c, somatic |
increases expression |
EXP |
butylparaben results in increased expression of CYCS protein |
CTD |
PMID:29319206 |
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NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
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G |
CYP11A1 |
cytochrome P450 family 11 subfamily A member 1 |
decreases expression |
ISO |
butylparaben results in decreased expression of CYP11A1 mRNA; butylparaben results in decreased expression of CYP11A1 protein |
CTD |
PMID:26888303 |
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NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646
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G |
CYP11B1 |
cytochrome P450 family 11 subfamily B member 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CYP11B1 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 8:142,872,357...142,879,825
Ensembl chr 8:142,872,356...142,879,846
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G |
CYP17A1 |
cytochrome P450 family 17 subfamily A member 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CYP17A1 mRNA |
CTD |
PMID:25607892 |
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NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472
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G |
CYP19A1 |
cytochrome P450 family 19 subfamily A member 1 |
decreases expression multiple interactions increases expression affects expression increases activity |
ISO EXP |
butylparaben results in decreased expression of CYP19A1 mRNA [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CYP19A1 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] affects the expression of CYP19A1 mRNA butylparaben results in decreased expression of CYP19A1 mRNA; butylparaben results in decreased expression of CYP19A1 protein butylparaben results in increased expression of CYP19A1 mRNA butylparaben affects the expression of CYP19A1 protein butylparaben results in increased activity of CYP19A1 protein |
CTD |
PMID:23744433 PMID:25607892 PMID:26888303 PMID:27122241 PMID:30817981 |
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NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601
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G |
CYP1A1 |
cytochrome P450 family 1 subfamily A member 1 |
decreases activity multiple interactions |
ISO EXP |
butylparaben results in decreased activity of CYP1A1 protein [butylparaben co-treated with triclocarban] results in increased expression of CYP1A1 mRNA |
CTD |
PMID:23524099 PMID:27432241 |
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NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
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G |
CYP1A2 |
cytochrome P450 family 1 subfamily A member 2 |
decreases activity |
ISO |
butylparaben results in decreased activity of CYP1A2 protein |
CTD |
PMID:27432241 |
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NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
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G |
CYP1B1 |
cytochrome P450 family 1 subfamily B member 1 |
multiple interactions increases expression |
EXP |
butylparaben promotes the reaction [bisphenol A results in increased expression of CYP1B1 mRNA] butylparaben results in increased expression of CYP1B1 mRNA |
CTD |
PMID:23524099 |
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NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
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G |
CYP2C18 |
cytochrome P450 family 2 subfamily C member 18 |
decreases activity |
ISO |
butylparaben results in decreased activity of CYP2C11 protein |
CTD |
PMID:27432241 |
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NCBI chr10:94,683,729...94,736,190
Ensembl chr10:94,683,729...94,736,190
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G |
CYP2E1 |
cytochrome P450 family 2 subfamily E member 1 |
decreases activity |
ISO |
butylparaben results in decreased activity of CYP2E1 protein |
CTD |
PMID:27432241 |
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NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
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G |
DCC |
DCC netrin 1 receptor |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of DCC mRNA |
CTD |
PMID:25607892 |
|
NCBI chr18:52,340,197...53,535,899
Ensembl chr18:52,340,197...53,535,899
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G |
DDIT3 |
DNA damage inducible transcript 3 |
increases expression |
EXP ISO |
butylparaben results in increased expression of DDIT3 protein butylparaben results in increased expression of DDIT3 mRNA |
CTD |
PMID:29319206 PMID:36277366 |
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NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
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G |
DIABLO |
diablo IAP-binding mitochondrial protein |
increases expression |
EXP |
butylparaben results in increased expression of DIABLO mRNA |
CTD |
PMID:24481588 |
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NCBI chr12:122,207,662...122,227,456
Ensembl chr12:122,207,668...122,226,062
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G |
DIO1 |
iodothyronine deiodinase 1 |
affects expression decreases activity |
ISO |
butylparaben affects the expression of DIO1 mRNA butylparaben results in decreased activity of DIO1 protein |
CTD |
PMID:32798586 |
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NCBI chr 1:53,894,187...53,911,086
Ensembl chr 1:53,891,239...53,911,086
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G |
DLG1 |
discs large MAGUK scaffold protein 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of DLG1 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 3:197,042,560...197,299,321
Ensembl chr 3:197,042,560...197,299,330
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G |
DLG4 |
discs large MAGUK scaffold protein 4 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of DLG4 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of DLG4 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of DLG4 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr17:7,187,187...7,220,050
Ensembl chr17:7,187,187...7,219,841
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G |
DLGAP3 |
DLG associated protein 3 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of DLGAP3 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of DLGAP3 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr 1:34,865,436...34,929,650
Ensembl chr 1:34,865,436...34,929,650
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G |
DNM1 |
dynamin 1 |
multiple interactions |
ISO |
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of DNM1 mRNA |
CTD |
PMID:34383603 |
|
NCBI chr 9:128,203,379...128,255,244
Ensembl chr 9:128,191,655...128,255,248
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G |
DNMT3A |
DNA methyltransferase 3 alpha |
increases expression multiple interactions |
ISO |
butylparaben results in increased expression of DNMT3A mRNA [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of DNMT3A mRNA |
CTD |
PMID:25607892 PMID:26888303 |
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NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590
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G |
DNMT3B |
DNA methyltransferase 3 beta |
increases expression |
ISO |
butylparaben results in increased expression of DNMT3B mRNA |
CTD |
PMID:26888303 |
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NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359
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G |
DPP6 |
dipeptidyl peptidase like 6 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of DPP6 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr 7:153,748,133...154,894,285
Ensembl chr 7:153,748,133...154,894,285
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G |
E2F1 |
E2F transcription factor 1 |
affects expression |
EXP |
butylparaben affects the expression of E2F1 mRNA |
CTD |
PMID:24481588 |
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NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385
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G |
E2F3 |
E2F transcription factor 3 |
affects expression |
EXP |
butylparaben affects the expression of E2F3 mRNA |
CTD |
PMID:24481588 |
|
NCBI chr 6:20,401,879...20,493,714
Ensembl chr 6:20,401,879...20,493,714
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G |
EFNA4 |
ephrin A4 |
increases expression |
EXP |
butylparaben results in increased expression of EFNA4 mRNA |
CTD |
PMID:17121429 |
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NCBI chr 1:155,063,740...155,069,553
Ensembl chr 1:155,063,737...155,069,553
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G |
EGF |
epidermal growth factor |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of EGF mRNA |
CTD |
PMID:25607892 |
|
NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
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G |
ELP6 |
elongator acetyltransferase complex subunit 6 |
increases expression |
EXP |
butylparaben results in increased expression of ELP6 mRNA |
CTD |
PMID:17121429 |
|
NCBI chr 3:47,495,640...47,513,712
Ensembl chr 3:47,495,640...47,513,712
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G |
ERBB2 |
erb-b2 receptor tyrosine kinase 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of ERBB2 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426
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G |
ERBB3 |
erb-b2 receptor tyrosine kinase 3 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of ERBB3 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of ERBB3 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr12:56,080,108...56,103,505
Ensembl chr12:56,076,799...56,103,505
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G |
ERBB4 |
erb-b2 receptor tyrosine kinase 4 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of ERBB4 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of ERBB4 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] affects the expression of ERBB4 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of ERBB4 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr 2:211,375,717...212,538,802
Ensembl chr 2:211,375,717...212,538,841
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G |
ERCC2 |
ERCC excision repair 2, TFIIH core complex helicase subunit |
increases expression |
EXP |
butylparaben results in increased expression of ERCC2 mRNA |
CTD |
PMID:17121429 |
|
NCBI chr19:45,349,837...45,370,573
Ensembl chr19:45,349,837...45,370,918
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G |
ERN1 |
endoplasmic reticulum to nucleus signaling 1 |
increases expression |
EXP |
butylparaben results in increased expression of ERN1 protein |
CTD |
PMID:29319206 |
|
NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819
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G |
ESR1 |
estrogen receptor 1 |
affects binding multiple interactions increases expression decreases activity decreases expression decreases methylation increases activity |
EXP ISO |
butylparaben binds to ESR1 protein; butylparaben metabolite binds to ESR1 protein [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of ESR1 mRNA; butylparaben inhibits the reaction [Estradiol binds to ESR1 protein]; Fulvestrant inhibits the reaction [butylparaben results in decreased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [butylparaben results in decreased expression of ESR1 protein] butylparaben results in increased expression of ESR1 mRNA; butylparaben results in increased expression of ESR1 protein butylparaben results in decreased activity of ESR1 protein butylparaben results in decreased expression of ESR1 mRNA; butylparaben results in decreased expression of ESR1 protein [butylparaben co-treated with NRG1 protein] promotes the reaction [ESR1 protein binds to MYC enhancer]; butylparaben binds to and results in increased activity of ESR1 protein; Fulvestrant inhibits the reaction [butylparaben results in increased activity of ESR1 protein] butylparaben results in decreased methylation of ESR1 promoter |
CTD |
PMID:11193391 PMID:15204698 PMID:19063592 PMID:19654335 PMID:20074635 PMID:20132880 PMID:20362049 PMID:20435135 PMID:22562034 PMID:23524099 PMID:23567241 PMID:25012808 PMID:25128701 PMID:26502914 PMID:26888303 PMID:27444704 PMID:29945225 PMID:34383603 More...
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NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
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G |
ESR2 |
estrogen receptor 2 |
affects binding decreases expression increases expression multiple interactions |
EXP ISO |
butylparaben binds to ESR2 protein butylparaben results in decreased expression of ESR2 mRNA butylparaben results in increased expression of ESR2 mRNA butylparaben binds to and results in increased activity of ESR2 protein butylparaben results in increased expression of ESR2 mRNA; butylparaben results in increased expression of ESR2 protein |
CTD |
PMID:11193391 PMID:18648085 PMID:20132880 PMID:23567241 PMID:25128701 PMID:26888303 More...
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NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112
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G |
ESRRG |
estrogen related receptor gamma |
multiple interactions |
EXP |
butylparaben inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]] |
CTD |
PMID:23583298 |
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NCBI chr 1:216,503,246...217,137,702
Ensembl chr 1:216,503,246...217,137,755
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G |
FAAH |
fatty acid amide hydrolase |
decreases activity |
ISO EXP |
butylparaben results in decreased activity of FAAH protein |
CTD |
PMID:27659731 |
|
NCBI chr 1:46,394,317...46,413,845
Ensembl chr 1:46,394,317...46,413,848
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G |
FABP4 |
fatty acid binding protein 4 |
increases expression multiple interactions |
EXP ISO |
butylparaben results in increased expression of FABP4 mRNA butylparaben promotes the reaction [Dexamethasone results in increased expression of FABP4 mRNA]; NR3C1 protein promotes the reaction [butylparaben results in increased expression of FABP4 mRNA]; PPARG mutant form inhibits the reaction [butylparaben results in increased expression of FABP4 mRNA]; PPARG protein promotes the reaction [butylparaben results in increased expression of FABP4 mRNA] |
CTD |
PMID:22956630 PMID:24155963 PMID:27659731 PMID:28527915 |
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NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236
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G |
FASN |
fatty acid synthase |
increases expression multiple interactions |
ISO EXP |
butylparaben results in increased expression of FASN mRNA butylparaben promotes the reaction [Dexamethasone results in increased expression of FASN mRNA] |
CTD |
PMID:22956630 |
|
NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
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G |
FBXL9P |
F-box and leucine rich repeat protein, pseudogene |
increases expression |
EXP |
butylparaben results in increased expression of FBXL9P mRNA |
CTD |
PMID:17121429 |
|
NCBI chr16:67,207,139...67,227,025
Ensembl chr16:67,207,139...67,227,048 Ensembl chr16:67,207,139...67,227,048
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G |
FGFR1 |
fibroblast growth factor receptor 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of FGFR1 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
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G |
FGFR2 |
fibroblast growth factor receptor 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of FGFR2 mRNA |
CTD |
PMID:25607892 |
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NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,332...121,598,458
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G |
FSHB |
follicle stimulating hormone subunit beta |
decreases expression decreases secretion |
ISO |
butylparaben results in decreased expression of FSHB protein butylparaben results in decreased secretion of FSHB protein |
CTD |
PMID:27444704 PMID:29350491 |
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NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261
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G |
FUS |
FUS RNA binding protein |
increases expression |
EXP |
butylparaben results in increased expression of FUS mRNA |
CTD |
PMID:17121429 |
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NCBI chr16:31,180,110...31,194,871
Ensembl chr16:31,180,138...31,191,605
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G |
FYN |
FYN proto-oncogene, Src family tyrosine kinase |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] affects the expression of FYN mRNA |
CTD |
PMID:25607892 |
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NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452
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G |
GABRA4 |
gamma-aminobutyric acid type A receptor subunit alpha4 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GABRA4 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 4:46,918,900...46,993,581
Ensembl chr 4:46,918,900...46,993,581
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G |
GABRB1 |
gamma-aminobutyric acid type A receptor subunit beta1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GABRB1 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 4:46,993,647...47,426,447
Ensembl chr 4:46,993,723...47,426,447
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G |
GLS |
glutaminase |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GLS mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of GLS mRNA |
CTD |
PMID:25607892 |
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NCBI chr 2:190,880,821...190,965,552
Ensembl chr 2:190,880,821...190,965,552
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G |
GPER1 |
G protein-coupled estrogen receptor 1 |
increases expression |
EXP |
butylparaben results in increased expression of GPER1 mRNA; butylparaben results in increased expression of GPER1 protein |
CTD |
PMID:17121429 PMID:26253279 |
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NCBI chr 7:1,087,118...1,093,810
Ensembl chr 7:1,082,208...1,093,815
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G |
GREB1 |
growth regulating estrogen receptor binding 1 |
increases expression multiple interactions |
EXP |
butylparaben metabolite results in increased expression of GREB1 mRNA; butylparaben results in increased expression of GREB1 mRNA Fulvestrant inhibits the reaction [butylparaben metabolite results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [butylparaben results in increased expression of GREB1 mRNA] |
CTD |
PMID:17121429 PMID:29945225 |
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NCBI chr 2:11,482,888...11,642,788
Ensembl chr 2:11,482,341...11,642,788
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G |
GRIA2 |
glutamate ionotropic receptor AMPA type subunit 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GRIA2 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 4:157,220,120...157,366,075
Ensembl chr 4:157,204,182...157,387,146
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G |
GRIA4 |
glutamate ionotropic receptor AMPA type subunit 4 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GRIA4 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of GRIA4 mRNA |
CTD |
PMID:25607892 |
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NCBI chr11:105,609,616...105,982,090
Ensembl chr11:105,609,535...105,982,090
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G |
GRID2 |
glutamate ionotropic receptor delta type subunit 2 |
multiple interactions |
ISO |
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of GRID2 mRNA |
CTD |
PMID:34383603 |
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NCBI chr 4:92,303,966...93,810,456
Ensembl chr 4:92,303,966...93,810,157
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G |
GRIK2 |
glutamate ionotropic receptor kainate type subunit 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GRIK2 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of GRIK2 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr 6:101,393,708...102,070,083
Ensembl chr 6:100,962,701...102,081,622
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G |
GRIK4 |
glutamate ionotropic receptor kainate type subunit 4 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of GRIK4 mRNA |
CTD |
PMID:25607892 |
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NCBI chr11:120,511,748...120,988,906
Ensembl chr11:120,511,746...120,988,906
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G |
GRIK5 |
glutamate ionotropic receptor kainate type subunit 5 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of GRIK5 mRNA |
CTD |
PMID:25607892 |
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NCBI chr19:41,998,324...42,070,206
Ensembl chr19:41,998,321...42,070,206
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G |
GRIN1 |
glutamate ionotropic receptor NMDA type subunit 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of GRIN1 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of GRIN1 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 9:137,139,154...137,168,756
Ensembl chr 9:137,138,346...137,168,756
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G |
GRIN2B |
glutamate ionotropic receptor NMDA type subunit 2B |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of GRIN2B mRNA |
CTD |
PMID:25607892 |
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NCBI chr12:13,537,337...13,982,134
Ensembl chr12:13,437,942...13,982,002
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G |
GRIN2C |
glutamate ionotropic receptor NMDA type subunit 2C |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of GRIN2C mRNA |
CTD |
PMID:25607892 |
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NCBI chr17:74,842,023...74,861,532
Ensembl chr17:74,842,023...74,861,504
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G |
GRIN2D |
glutamate ionotropic receptor NMDA type subunit 2D |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GRIN2D mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of GRIN2D mRNA; [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of GRIN2D mRNA |
CTD |
PMID:25607892 PMID:34383603 |
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NCBI chr19:48,393,668...48,444,931
Ensembl chr19:48,393,668...48,444,931
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G |
GRIN3A |
glutamate ionotropic receptor NMDA type subunit 3A |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of GRIN3A mRNA |
CTD |
PMID:25607892 |
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NCBI chr 9:101,569,352...101,738,647
Ensembl chr 9:101,569,352...101,738,647
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G |
GRIP1 |
glutamate receptor interacting protein 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GRIP1 mRNA |
CTD |
PMID:25607892 |
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NCBI chr12:66,347,431...67,069,338
Ensembl chr12:66,347,431...67,069,162
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G |
GSK3B |
glycogen synthase kinase 3 beta |
decreases phosphorylation |
EXP |
butylparaben results in decreased phosphorylation of GSK3B protein |
CTD |
PMID:29319206 |
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NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
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G |
HES6 |
hes family bHLH transcription factor 6 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of HES6 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 2:238,238,267...238,240,038
Ensembl chr 2:238,238,267...238,240,662
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G |
HEXB |
hexosaminidase subunit beta |
multiple interactions |
ISO |
zinc chloride inhibits the reaction [butylparaben results in increased secretion of HEXB protein] |
CTD |
PMID:15272608 |
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NCBI chr 5:74,640,023...74,721,288
Ensembl chr 5:74,640,023...74,722,647
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G |
HPS6 |
HPS6 biogenesis of lysosomal organelles complex 2 subunit 3 |
increases expression |
EXP |
butylparaben results in increased expression of HPS6 mRNA |
CTD |
PMID:17121429 |
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NCBI chr10:102,065,349...102,068,036
Ensembl chr10:102,065,349...102,068,036
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G |
HR |
HR lysine demethylase and nuclear receptor corepressor |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of HR mRNA |
CTD |
PMID:25607892 |
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NCBI chr 8:22,114,419...22,131,052
Ensembl chr 8:22,114,419...22,133,384
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G |
HSD17B10 |
hydroxysteroid 17-beta dehydrogenase 10 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of HSD17B10 mRNA |
CTD |
PMID:25607892 |
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NCBI chr X:53,431,258...53,434,376
Ensembl chr X:53,431,258...53,434,370
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G |
HSD17B8 |
hydroxysteroid 17-beta dehydrogenase 8 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of HSD17B8 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 6:33,204,655...33,206,831
Ensembl chr 6:33,204,655...33,206,831
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
EXP ISO |
butylparaben results in increased expression of HSPA5 protein butylparaben results in increased expression of HSPA5 mRNA |
CTD |
PMID:29319206 PMID:36277366 |
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NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
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G |
HSPB8 |
heat shock protein family B (small) member 8 |
increases expression |
EXP |
butylparaben results in increased expression of HSPB8 mRNA |
CTD |
PMID:23524099 |
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NCBI chr12:119,178,931...119,194,746
Ensembl chr12:119,171,555...119,224,855
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G |
IGDCC3 |
immunoglobulin superfamily DCC subclass member 3 |
increases expression |
EXP |
butylparaben results in increased expression of IGDCC3 mRNA |
CTD |
PMID:17121429 |
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NCBI chr15:65,327,127...65,378,002
Ensembl chr15:65,327,127...65,378,002
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G |
IGF1R |
insulin like growth factor 1 receptor |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of IGF1R mRNA |
CTD |
PMID:25607892 |
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NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530
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G |
IGF2R |
insulin like growth factor 2 receptor |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of IGF2R mRNA |
CTD |
PMID:25607892 |
|
NCBI chr 6:159,969,082...160,111,504
Ensembl chr 6:159,969,082...160,113,507
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G |
IL17RB |
interleukin 17 receptor B |
increases expression |
EXP |
butylparaben results in increased expression of IL17RB mRNA |
CTD |
PMID:17121429 |
|
NCBI chr 3:53,846,568...53,865,794
Ensembl chr 3:53,846,568...53,865,794
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G |
IL1RAPL1 |
interleukin 1 receptor accessory protein like 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of IL1RAPL1 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr X:28,587,446...29,956,718
Ensembl chr X:28,587,446...29,956,718
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G |
INCENP |
inner centromere protein |
increases expression |
EXP |
butylparaben results in increased expression of INCENP mRNA |
CTD |
PMID:17121429 |
|
NCBI chr11:62,124,011...62,153,169
Ensembl chr11:62,123,998...62,153,169
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G |
INS |
insulin |
multiple interactions |
EXP |
butylparaben promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein]; butylparaben promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein] |
CTD |
PMID:31016361 |
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NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
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G |
JAG1 |
jagged canonical Notch ligand 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of JAG1 mRNA |
CTD |
PMID:25607892 |
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NCBI chr20:10,637,684...10,673,999
Ensembl chr20:10,637,684...10,673,999
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G |
KCNC1 |
potassium voltage-gated channel subfamily C member 1 |
increases expression |
EXP |
butylparaben results in increased expression of KCNC1 mRNA |
CTD |
PMID:17121429 |
|
NCBI chr11:17,734,781...17,783,057
Ensembl chr11:17,734,774...17,856,804
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G |
KCNF1 |
potassium voltage-gated channel modifier subfamily F member 1 |
increases expression |
EXP |
butylparaben results in increased expression of KCNF1 mRNA |
CTD |
PMID:17121429 |
|
NCBI chr 2:10,911,934...10,914,225
Ensembl chr 2:10,911,934...10,914,225
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G |
KISS1 |
KiSS-1 metastasis suppressor |
multiple interactions |
ISO |
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of KISS1 mRNA |
CTD |
PMID:34383603 |
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NCBI chr 1:204,190,341...204,196,491
Ensembl chr 1:204,190,341...204,196,491
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G |
KMT2D |
lysine methyltransferase 2D |
increases expression |
EXP |
butylparaben results in increased expression of KMT2D mRNA |
CTD |
PMID:17121429 |
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NCBI chr12:49,018,978...49,060,794
Ensembl chr12:49,018,975...49,060,794
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G |
KRT8 |
keratin 8 |
increases expression |
EXP |
butylparaben results in increased expression of KRT8 mRNA |
CTD |
PMID:17121429 |
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NCBI chr12:52,897,191...52,949,860
Ensembl chr12:52,897,187...52,949,954
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G |
KRT82 |
keratin 82 |
increases expression |
EXP |
butylparaben results in increased expression of KRT82 mRNA |
CTD |
PMID:17121429 |
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NCBI chr12:52,393,931...52,406,335
Ensembl chr12:52,393,931...52,406,335
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G |
LEF1 |
lymphoid enhancer binding factor 1 |
increases expression |
EXP |
butylparaben results in increased expression of LEF1 mRNA |
CTD |
PMID:17121429 |
|
NCBI chr 4:108,047,548...108,168,932
Ensembl chr 4:108,047,545...108,168,956
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G |
LEP |
leptin |
decreases expression increases expression |
EXP ISO |
butylparaben results in decreased expression of LEP mRNA butylparaben results in increased expression of LEP mRNA |
CTD |
PMID:22956630 |
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NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629
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G |
LHB |
luteinizing hormone subunit beta |
multiple interactions decreases expression decreases secretion |
ISO |
butylparaben promotes the reaction [Triclosan results in decreased secretion of LHB protein]; Triclosan promotes the reaction [butylparaben results in decreased secretion of LHB protein] butylparaben results in decreased expression of LHB protein |
CTD |
PMID:27444704 PMID:29350491 |
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NCBI chr19:49,015,980...49,019,498
Ensembl chr19:49,015,980...49,017,091
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G |
LIN7A |
lin-7 homolog A, crumbs cell polarity complex component |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of LIN7A mRNA |
CTD |
PMID:25607892 |
|
NCBI chr12:80,792,520...80,937,934
Ensembl chr12:80,792,520...80,937,934
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G |
LMOD1 |
leiomodin 1 |
increases expression |
EXP |
butylparaben results in increased expression of LMOD1 mRNA |
CTD |
PMID:17121429 |
|
NCBI chr 1:201,896,456...201,946,548
Ensembl chr 1:201,896,456...201,946,548
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G |
LPIN1 |
lipin 1 |
increases expression multiple interactions |
ISO |
butylparaben results in increased expression of LPIN1 mRNA [Dexamethasone co-treated with butylparaben] results in increased expression of LPIN1 mRNA; NR3C1 mutant form inhibits the reaction [butylparaben results in increased expression of LPIN1 mRNA] |
CTD |
PMID:22956630 |
|
NCBI chr 2:11,677,544...11,827,409
Ensembl chr 2:11,677,595...11,827,409
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G |
MAGI2 |
membrane associated guanylate kinase, WW and PDZ domain containing 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of MAGI2 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of MAGI2 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr 7:78,017,055...79,453,667
Ensembl chr 7:78,017,055...79,453,667
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G |
MAPK1 |
mitogen-activated protein kinase 1 |
increases phosphorylation |
EXP |
butylparaben results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:26253279 PMID:29319206 |
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NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
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G |
MAPK3 |
mitogen-activated protein kinase 3 |
increases phosphorylation |
EXP |
butylparaben results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:26253279 PMID:29319206 |
|
NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
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G |
MASP1 |
MBL associated serine protease 1 |
increases expression |
EXP |
butylparaben results in increased expression of MASP1 mRNA |
CTD |
PMID:17121429 |
|
NCBI chr 3:187,217,282...187,291,737
Ensembl chr 3:187,217,282...187,291,980
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G |
MDGA2 |
MAM domain containing glycosylphosphatidylinositol anchor 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of MDGA2 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of MDGA2 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr14:46,839,623...47,675,605
Ensembl chr14:46,840,092...47,675,605
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G |
MET |
MET proto-oncogene, receptor tyrosine kinase |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of MET mRNA |
CTD |
PMID:25607892 |
|
NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377
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G |
MMP3 |
matrix metallopeptidase 3 |
multiple interactions |
ISO |
[enzacamene co-treated with octylmethoxycinnamate co-treated with bisphenol A co-treated with butylparaben] results in increased expression of MMP3 mRNA |
CTD |
PMID:25305543 |
|
NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609
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G |
MYC |
MYC proto-oncogene, bHLH transcription factor |
increases expression multiple interactions |
EXP |
butylparaben results in increased expression of MYC mRNA [butylparaben co-treated with NRG1 protein] promotes the reaction [ESR1 protein binds to MYC enhancer]; [NRG1 protein co-treated with butylparaben] results in increased expression of MYC protein; butylparaben promotes the reaction [NRG1 protein results in increased expression of MYC mRNA]; NRG1 protein promotes the reaction [butylparaben results in increased expression of MYC mRNA] |
CTD |
PMID:26502914 |
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NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
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G |
NCOA2 |
nuclear receptor coactivator 2 |
multiple interactions |
EXP |
butylparaben inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]] |
CTD |
PMID:23583298 |
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NCBI chr 8:70,109,782...70,456,446
Ensembl chr 8:70,109,782...70,403,808
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G |
NF1 |
neurofibromin 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of NF1 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of NF1 mRNA |
CTD |
PMID:25607892 |
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NCBI chr17:31,094,927...31,377,677
Ensembl chr17:31,094,927...31,382,116
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G |
NLGN1 |
neuroligin 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NLGN1 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of NLGN1 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of NLGN1 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 3:173,395,952...174,294,372
Ensembl chr 3:173,396,284...174,294,372
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G |
NOTCH2 |
notch receptor 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NOTCH2 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of NOTCH2 mRNA |
CTD |
PMID:25607892 |
|
NCBI chr 1:119,911,553...120,069,662
Ensembl chr 1:119,911,553...120,100,779
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G |
NOTCH4 |
notch receptor 4 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NOTCH4 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of NOTCH4 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 6:32,194,843...32,224,067
Ensembl chr 6:32,194,843...32,224,067
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G |
NR1I2 |
nuclear receptor subfamily 1 group I member 2 |
increases expression |
ISO EXP |
butylparaben results in increased expression of NR1I2 mRNA |
CTD |
PMID:31472229 |
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NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487
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G |
NR1I3 |
nuclear receptor subfamily 1 group I member 3 |
increases expression |
ISO |
butylparaben results in increased expression of NR1I3 mRNA |
CTD |
PMID:31472229 |
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NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244
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G |
NR3C1 |
nuclear receptor subfamily 3 group C member 1 |
multiple interactions increases response to substance increases activity |
ISO EXP |
NR3C1 mutant form inhibits the reaction [butylparaben results in increased expression of LPIN1 mRNA]; NR3C1 protein promotes the reaction [butylparaben results in decreased expression of ALPL mRNA]; NR3C1 protein promotes the reaction [butylparaben results in decreased expression of SPP1 mRNA]; NR3C1 protein promotes the reaction [butylparaben results in increased expression of FABP4 mRNA]; NR3C1 protein promotes the reaction [butylparaben results in increased expression of PLIN1 mRNA] [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of NR3C1 mRNA [butylparaben co-treated with propylparaben] results in increased activity of NR3C1 protein; [Diethylhexyl Phthalate co-treated with butylparaben co-treated with propylparaben] results in increased activity of NR3C1 protein; [Diethylhexyl Phthalate co-treated with butylparaben co-treated with tetramethrin co-treated with propylparaben] results in increased activity of NR3C1 protein; [Diethylhexyl Phthalate co-treated with butylparaben co-treated with tetramethrin] results in increased activity of NR3C1 protein; [Diethylhexyl Phthalate co-treated with butylparaben] results in increased activity of NR3C1 protein NR3C1 protein results in increased susceptibility to butylparaben butylparaben results in increased activity of NR3C1 protein |
CTD |
PMID:22956630 PMID:25448277 PMID:28527915 PMID:34383603 |
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NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512
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G |
NR3C2 |
nuclear receptor subfamily 3 group C member 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NR3C2 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 4:148,078,764...148,445,508
Ensembl chr 4:148,078,762...148,444,698
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G |
NR5A1 |
nuclear receptor subfamily 5 group A member 1 |
decreases expression |
ISO |
butylparaben results in decreased expression of NR5A1 mRNA |
CTD |
PMID:27122241 |
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NCBI chr 9:124,481,236...124,507,399
Ensembl chr 9:124,481,236...124,507,420
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G |
NRCAM |
neuronal cell adhesion molecule |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NRCAM mRNA |
CTD |
PMID:25607892 |
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NCBI chr 7:108,147,649...108,456,720
Ensembl chr 7:108,147,623...108,456,717
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G |
NRG1 |
neuregulin 1 |
multiple interactions |
EXP ISO |
[butylparaben co-treated with NRG1 protein] promotes the reaction [ESR1 protein binds to MYC enhancer]; [NRG1 protein co-treated with butylparaben] results in increased expression of MYC protein; butylparaben promotes the reaction [NRG1 protein results in increased expression of MYC mRNA]; NRG1 protein promotes the reaction [butylparaben results in increased expression of MYC mRNA] [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of NRG1 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of NRG1 mRNA |
CTD |
PMID:25607892 PMID:26502914 |
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NCBI chr 8:31,639,245...32,774,046
Ensembl chr 8:31,639,222...32,855,666
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G |
NRXN1 |
neurexin 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NRXN1 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 2:49,918,503...51,032,132
Ensembl chr 2:49,918,503...51,225,575
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G |
NRXN2 |
neurexin 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NRXN2 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of NRXN2 mRNA |
CTD |
PMID:25607892 |
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NCBI chr11:64,606,174...64,723,197
Ensembl chr11:64,606,174...64,723,197
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G |
NTRK1 |
neurotrophic receptor tyrosine kinase 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NTRK1 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 1:156,815,750...156,881,850
Ensembl chr 1:156,815,636...156,881,850
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G |
NTRK2 |
neurotrophic receptor tyrosine kinase 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of NTRK2 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of NTRK2 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 9:84,668,522...85,027,054
Ensembl chr 9:84,668,375...85,095,751
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G |
NTRK3 |
neurotrophic receptor tyrosine kinase 3 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NTRK3 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of NTRK3 mRNA |
CTD |
PMID:25607892 |
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NCBI chr15:87,859,751...88,256,739
Ensembl chr15:87,859,751...88,256,791
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G |
NXPH3 |
neurexophilin 3 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of NXPH3 mRNA |
CTD |
PMID:25607892 |
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NCBI chr17:49,575,871...49,583,827
Ensembl chr17:49,575,871...49,583,827
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G |
OTOF |
otoferlin |
increases expression |
EXP |
butylparaben results in increased expression of OTOF mRNA |
CTD |
PMID:17121429 |
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NCBI chr 2:26,457,203...26,558,756
Ensembl chr 2:26,457,203...26,558,756
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G |
OXT |
oxytocin/neurophysin I prepropeptide |
multiple interactions |
ISO |
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of OXT mRNA |
CTD |
PMID:34383603 |
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NCBI chr20:3,071,620...3,072,517
Ensembl chr20:3,071,620...3,072,517
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G |
PCDHA3 |
protocadherin alpha 3 |
increases expression |
EXP |
butylparaben results in increased expression of PCDHA3 mRNA |
CTD |
PMID:17121429 |
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NCBI chr 5:140,801,057...141,012,347
Ensembl chr 5:140,801,028...141,012,347
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G |
PCDHGC3 |
protocadherin gamma subfamily C, 3 |
increases expression |
EXP |
butylparaben results in increased expression of PCDHGC3 mRNA |
CTD |
PMID:17121429 |
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NCBI chr 5:141,475,966...141,512,975
Ensembl chr 5:141,475,947...141,512,977
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G |
PEX14 |
peroxisomal biogenesis factor 14 |
increases expression |
EXP |
butylparaben results in increased expression of PEX14 mRNA |
CTD |
PMID:17121429 |
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NCBI chr 1:10,474,950...10,630,758
Ensembl chr 1:10,472,288...10,630,758
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G |
PGR |
progesterone receptor |
increases expression multiple interactions |
ISO EXP |
butylparaben results in increased expression of PGR mRNA; butylparaben results in increased expression of PGR protein [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of PGR mRNA; Fulvestrant inhibits the reaction [butylparaben results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [butylparaben results in increased expression of PGR protein] Silver inhibits the reaction [butylparaben results in increased expression of PGR mRNA] |
CTD |
PMID:17121429 PMID:19654335 PMID:23524099 PMID:25128701 PMID:25607892 PMID:29074358 More...
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NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813
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G |
PI4KA |
phosphatidylinositol 4-kinase alpha |
increases expression |
EXP |
butylparaben results in increased expression of PI4KA mRNA |
CTD |
PMID:17121429 |
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NCBI chr22:20,707,691...20,858,811
Ensembl chr22:20,707,691...20,859,417
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G |
PLIN1 |
perilipin 1 |
increases expression multiple interactions |
ISO |
butylparaben results in increased expression of PLIN1 mRNA NR3C1 protein promotes the reaction [butylparaben results in increased expression of PLIN1 mRNA]; PPARG mutant form inhibits the reaction [butylparaben results in increased expression of PLIN1 mRNA]; PPARG protein promotes the reaction [butylparaben results in increased expression of PLIN1 mRNA] |
CTD |
PMID:22956630 PMID:28527915 |
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NCBI chr15:89,664,367...89,679,367
Ensembl chr15:89,664,367...89,679,427
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G |
POMC |
proopiomelanocortin |
multiple interactions |
ISO |
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] affects the expression of POMC mRNA |
CTD |
PMID:34383603 |
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NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903
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G |
PPARA |
peroxisome proliferator activated receptor alpha |
increases expression |
ISO |
butylparaben results in increased expression of PPARA mRNA |
CTD |
PMID:31472229 |
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NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
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G |
PPARG |
peroxisome proliferator activated receptor gamma |
multiple interactions increases activity increases expression increases response to substance |
ISO EXP |
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [butylparaben results in increased expression of PPARG mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [butylparaben results in increased expression of PPARG mRNA]; butylparaben promotes the reaction [Dexamethasone results in increased expression of PPARG mRNA]; Mifepristone inhibits the reaction [butylparaben results in increased expression of PPARG mRNA]; PPARG mutant form inhibits the reaction [butylparaben results in increased expression of FABP4 mRNA]; PPARG mutant form inhibits the reaction [butylparaben results in increased expression of PLIN1 mRNA]; PPARG protein inhibits the reaction [butylparaben results in decreased expression of SPP1 mRNA]; PPARG protein promotes the reaction [butylparaben binds to and results in increased activity of PPARG protein]; PPARG protein promotes the reaction [butylparaben results in decreased expression of ALPL mRNA]; PPARG protein promotes the reaction [butylparaben results in increased expression of CEBPA mRNA]; PPARG protein promotes the reaction [butylparaben results in increased expression of FABP4 mRNA]; PPARG protein promotes the reaction [butylparaben results in increased expression of PLIN1 mRNA] butylparaben results in increased activity of PPARG protein PPARG protein results in increased susceptibility to butylparaben |
CTD |
PMID:22956630 PMID:24155963 PMID:27659731 PMID:28527915 |
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NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
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G |
PPP1R1B |
protein phosphatase 1 regulatory inhibitor subunit 1B |
multiple interactions |
ISO |
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of PPP1R1B mRNA |
CTD |
PMID:34383603 |
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NCBI chr17:39,626,707...39,636,624
Ensembl chr17:39,626,740...39,636,626
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G |
PRKN |
parkin RBR E3 ubiquitin protein ligase |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of PRKN mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of PRKN mRNA |
CTD |
PMID:25607892 |
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NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775
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G |
PRLR |
prolactin receptor |
increases expression |
EXP |
butylparaben results in increased expression of PRLR mRNA |
CTD |
PMID:17121429 |
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NCBI chr 5:35,048,756...35,230,487
Ensembl chr 5:35,048,756...35,230,487
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G |
PYROXD2 |
pyridine nucleotide-disulphide oxidoreductase domain 2 |
decreases expression |
EXP |
butylparaben results in decreased expression of PYROXD2 mRNA |
CTD |
PMID:17121429 |
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NCBI chr10:98,383,568...98,415,182
Ensembl chr10:98,383,565...98,415,182
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G |
RELN |
reelin |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of RELN mRNA |
CTD |
PMID:25607892 |
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NCBI chr 7:103,471,789...103,989,658
Ensembl chr 7:103,471,381...103,989,658
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G |
ROBO1 |
roundabout guidance receptor 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of ROBO1 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 3:78,597,239...79,767,998
Ensembl chr 3:78,597,239...79,767,998
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G |
RPS6 |
ribosomal protein S6 |
multiple interactions decreases phosphorylation |
EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [butylparaben results in decreased phosphorylation of RPS6 protein] |
CTD |
PMID:29319206 |
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NCBI chr 9:19,375,715...19,380,236
Ensembl chr 9:19,375,715...19,380,236
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G |
RPS6KB1 |
ribosomal protein S6 kinase B1 |
decreases phosphorylation multiple interactions |
EXP |
butylparaben results in decreased phosphorylation of RPS6KB1 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [butylparaben results in decreased phosphorylation of RPS6KB1 protein]; U 0126 inhibits the reaction [butylparaben results in decreased phosphorylation of RPS6KB1 protein] |
CTD |
PMID:29319206 |
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NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574
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G |
RUNX2 |
RUNX family transcription factor 2 |
decreases expression |
ISO |
butylparaben results in decreased expression of RUNX2 mRNA |
CTD |
PMID:28527915 |
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NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349
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G |
S100G |
S100 calcium binding protein G |
multiple interactions increases expression |
ISO |
Fulvestrant inhibits the reaction [butylparaben results in increased expression of S100G mRNA]; Fulvestrant inhibits the reaction [butylparaben results in increased expression of S100G protein] butylparaben results in increased expression of S100G mRNA; butylparaben results in increased expression of S100G protein |
CTD |
PMID:19654335 |
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NCBI chr X:16,650,158...16,654,670
Ensembl chr X:16,650,158...16,654,670
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G |
SHANK1 |
SH3 and multiple ankyrin repeat domains 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of SHANK1 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of SHANK1 mRNA |
CTD |
PMID:25607892 |
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NCBI chr19:50,659,255...50,719,802
Ensembl chr19:50,659,255...50,719,802
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G |
SHANK2 |
SH3 and multiple ankyrin repeat domains 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of SHANK2 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of SHANK2 mRNA |
CTD |
PMID:25607892 |
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NCBI chr11:70,467,854...71,253,228
Ensembl chr11:70,467,854...71,252,577
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G |
SHANK3 |
SH3 and multiple ankyrin repeat domains 3 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of SHANK3 mRNA |
CTD |
PMID:25607892 |
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NCBI chr22:50,672,823...50,733,212
Ensembl chr22:50,674,415...50,733,212
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G |
SIAH2 |
siah E3 ubiquitin protein ligase 2 |
decreases expression |
EXP |
butylparaben results in decreased expression of SIAH2 mRNA |
CTD |
PMID:17121429 |
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NCBI chr 3:150,741,125...150,763,169
Ensembl chr 3:150,741,125...150,763,477
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G |
SLC17A7 |
solute carrier family 17 member 7 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of SLC17A7 mRNA |
CTD |
PMID:25607892 |
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NCBI chr19:49,429,401...49,441,527
Ensembl chr19:49,429,401...49,442,360
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G |
SLC1A1 |
solute carrier family 1 member 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of SLC1A1 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 9:4,490,468...4,587,469
Ensembl chr 9:4,490,468...4,587,469
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G |
SLC1A2 |
solute carrier family 1 member 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of SLC1A2 mRNA |
CTD |
PMID:25607892 |
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NCBI chr11:35,251,205...35,420,507
Ensembl chr11:35,251,205...35,420,063
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G |
SLC1A3 |
solute carrier family 1 member 3 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of SLC1A3 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of SLC1A3 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 5:36,606,606...36,688,334
Ensembl chr 5:36,596,588...36,688,334
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SLC1A6 |
solute carrier family 1 member 6 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of SLC1A6 mRNA |
CTD |
PMID:25607892 |
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NCBI chr19:14,950,033...15,010,643
Ensembl chr19:14,950,033...15,022,990
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SLC22A2 |
solute carrier family 22 member 2 |
multiple interactions |
EXP |
butylparaben inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] |
CTD |
PMID:21599003 |
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NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638
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SLIT1 |
slit guidance ligand 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of SLIT1 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of SLIT1 mRNA |
CTD |
PMID:25607892 |
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NCBI chr10:96,998,038...97,185,959
Ensembl chr10:96,998,038...97,185,959
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SMC1A |
structural maintenance of chromosomes 1A |
increases expression |
EXP |
butylparaben results in increased expression of SMC1A mRNA |
CTD |
PMID:17121429 |
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NCBI chr X:53,374,149...53,422,728
Ensembl chr X:53,374,149...53,422,728
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SOX15 |
SRY-box transcription factor 15 |
increases expression |
EXP |
butylparaben results in increased expression of SOX15 mRNA |
CTD |
PMID:17121429 |
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NCBI chr17:7,588,178...7,590,094
Ensembl chr17:7,588,178...7,590,094
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SPP1 |
secreted phosphoprotein 1 |
decreases expression multiple interactions |
ISO |
butylparaben results in decreased expression of SPP1 mRNA NR3C1 protein promotes the reaction [butylparaben results in decreased expression of SPP1 mRNA]; PPARG protein inhibits the reaction [butylparaben results in decreased expression of SPP1 mRNA] |
CTD |
PMID:28527915 |
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NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
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SPTBN2 |
spectrin beta, non-erythrocytic 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of SPTBN2 mRNA |
CTD |
PMID:25607892 |
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NCBI chr11:66,682,497...66,744,682
Ensembl chr11:66,682,497...66,744,670
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STAR |
steroidogenic acute regulatory protein |
decreases expression |
ISO |
butylparaben results in decreased expression of STAR mRNA; butylparaben results in decreased expression of STAR protein |
CTD |
PMID:18648085 PMID:26888303 |
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NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
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STMN2 |
stathmin 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of STMN2 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 8:79,611,117...79,666,158
Ensembl chr 8:79,611,117...79,666,158
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STS |
steroid sulfatase |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of STS mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of STS mRNA |
CTD |
PMID:25607892 |
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NCBI chr X:7,147,290...7,354,641
Ensembl chr X:7,147,237...7,804,358
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STX1B |
syntaxin 1B |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of STX1B mRNA |
CTD |
PMID:25607892 |
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NCBI chr16:30,989,256...31,010,638
Ensembl chr16:30,989,256...31,010,638
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STXBP1 |
syntaxin binding protein 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of STXBP1 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of STXBP1 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 9:127,611,912...127,696,029
Ensembl chr 9:127,579,370...127,696,027
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SULT1E1 |
sulfotransferase family 1E member 1 |
decreases expression |
ISO |
butylparaben results in decreased expression of SULT1E1 mRNA; butylparaben results in decreased expression of SULT1E1 protein |
CTD |
PMID:26888303 |
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NCBI chr 4:69,821,122...69,860,145
Ensembl chr 4:69,841,212...69,860,145
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SYNGAP1 |
synaptic Ras GTPase activating protein 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of SYNGAP1 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 6:33,418,167...33,453,689
Ensembl chr 6:33,419,661...33,453,689
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SYP |
synaptophysin |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of SYP mRNA |
CTD |
PMID:25607892 |
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NCBI chr X:49,187,815...49,200,193
Ensembl chr X:49,187,815...49,200,218
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SYT6 |
synaptotagmin 6 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of SYT6 mRNA |
CTD |
PMID:25607892 |
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NCBI chr 1:114,089,292...114,153,869
Ensembl chr 1:114,089,291...114,153,880
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TCEA3 |
transcription elongation factor A3 |
increases expression |
EXP |
butylparaben results in increased expression of TCEA3 mRNA |
CTD |
PMID:17121429 |
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NCBI chr 1:23,380,909...23,424,748
Ensembl chr 1:23,380,909...23,424,748
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TFAP2B |
transcription factor AP-2 beta |
increases expression |
EXP |
butylparaben results in increased expression of TFAP2B mRNA |
CTD |
PMID:37690743 |
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NCBI chr 6:50,818,355...50,847,619
Ensembl chr 6:50,818,723...50,847,619
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TFF1 |
trefoil factor 1 |
increases expression multiple interactions |
EXP |
butylparaben results in increased expression of TFF1 mRNA Fulvestrant inhibits the reaction [butylparaben results in increased expression of TFF1 mRNA]; Silver inhibits the reaction [butylparaben results in increased expression of TFF1 mRNA] |
CTD |
PMID:16797915 PMID:17121429 PMID:22562034 PMID:23524099 PMID:29074358 |
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NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535
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TGFB1 |
transforming growth factor beta 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of TGFB1 mRNA |
CTD |
PMID:25607892 |
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NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
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TH |
tyrosine hydroxylase |
multiple interactions |
ISO |
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of TH mRNA |
CTD |
PMID:34383603 |
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NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815
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TNFRSF10A |
TNF receptor superfamily member 10a |
increases expression |
EXP |
butylparaben results in increased expression of TNFRSF10A mRNA |
CTD |
PMID:24481588 |
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NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,102
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TNFRSF11B |
TNF receptor superfamily member 11b |
multiple interactions |
EXP |
butylparaben promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein] |
CTD |
PMID:31016361 |
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NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885
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TNFRSF1A |
TNF receptor superfamily member 1A |
increases expression |
EXP |
butylparaben results in increased expression of TNFRSF1A mRNA |
CTD |
PMID:24481588 |
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NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114
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TNFRSF21 |
TNF receptor superfamily member 21 |
decreases expression |
EXP |
butylparaben results in decreased expression of TNFRSF21 mRNA |
CTD |
PMID:24481588 |
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NCBI chr 6:47,231,532...47,309,905
Ensembl chr 6:47,231,532...47,309,905
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TPO |
thyroid peroxidase |
increases expression increases activity |
ISO |
butylparaben results in increased expression of TPO mRNA butylparaben results in increased activity of TPO protein |
CTD |
PMID:32798586 |
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NCBI chr 2:1,374,047...1,543,673
Ensembl chr 2:1,374,066...1,543,711
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TSC2 |
TSC complex subunit 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of TSC2 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of TSC2 mRNA |
CTD |
PMID:25607892 |
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NCBI chr16:2,047,985...2,089,491
Ensembl chr16:2,047,967...2,089,491
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TSHB |
thyroid stimulating hormone subunit beta |
increases expression |
ISO |
butylparaben results in increased expression of TSHB protein |
CTD |
PMID:32798586 |
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NCBI chr 1:115,029,826...115,034,309
Ensembl chr 1:115,029,826...115,034,302
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TSNAX |
translin associated factor X |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of TSNAX mRNA |
CTD |
PMID:25607892 |
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NCBI chr 1:231,528,669...231,566,524
Ensembl chr 1:231,528,541...231,566,524
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TSPO |
translocator protein |
decreases expression |
ISO |
butylparaben results in decreased expression of TSPO mRNA |
CTD |
PMID:18648085 |
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NCBI chr22:43,151,559...43,163,242
Ensembl chr22:43,151,547...43,163,242
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UBD |
ubiquitin D |
decreases expression |
EXP |
butylparaben results in decreased expression of UBD mRNA |
CTD |
PMID:17121429 |
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NCBI chr 6:29,555,515...29,559,732
Ensembl chr 6:29,555,515...29,559,732
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UGT2B15 |
UDP glucuronosyltransferase family 2 member B15 |
increases expression |
EXP |
butylparaben results in increased expression of UGT2B15 mRNA |
CTD |
PMID:23524099 |
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NCBI chr 4:68,646,597...68,670,652
Ensembl chr 4:68,646,597...68,670,652
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UNC5A |
unc-5 netrin receptor A |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of UNC5A mRNA |
CTD |
PMID:25607892 |
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NCBI chr 5:176,810,559...176,880,898
Ensembl chr 5:176,810,519...176,880,898
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UNC5B |
unc-5 netrin receptor B |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of UNC5B mRNA |
CTD |
PMID:25607892 |
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NCBI chr10:71,212,570...71,302,864
Ensembl chr10:71,212,570...71,302,864
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UNC5C |
unc-5 netrin receptor C |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of UNC5C mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of UNC5C mRNA |
CTD |
PMID:25607892 |
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NCBI chr 4:95,162,504...95,548,973
Ensembl chr 4:95,162,504...95,549,206
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VEGFA |
vascular endothelial growth factor A |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of VEGFA mRNA |
CTD |
PMID:25607892 |
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NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
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VILL |
villin like |
increases expression |
EXP |
butylparaben results in increased expression of VILL mRNA |
CTD |
PMID:17121429 |
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NCBI chr 3:37,987,978...38,007,185
Ensembl chr 3:37,988,059...38,007,188
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VLDLR |
very low density lipoprotein receptor |
multiple interactions |
ISO |
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of VLDLR mRNA |
CTD |
PMID:25607892 |
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NCBI chr 9:2,621,787...2,660,056
Ensembl chr 9:2,621,182...2,660,056
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WNK4 |
WNK lysine deficient protein kinase 4 |
increases expression |
EXP |
butylparaben results in increased expression of WNK4 mRNA |
CTD |
PMID:17121429 |
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NCBI chr17:42,780,610...42,797,066
Ensembl chr17:42,780,610...42,797,066
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G |
XBP1 |
X-box binding protein 1 |
increases expression |
ISO |
butylparaben results in increased expression of XBP1 mRNA; butylparaben results in increased expression of XBP1 mRNA alternative form |
CTD |
PMID:36277366 |
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NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597
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ZNF397 |
zinc finger protein 397 |
increases expression |
EXP |
butylparaben results in increased expression of ZNF397 mRNA |
CTD |
PMID:17121429 |
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NCBI chr18:35,241,034...35,259,227
Ensembl chr18:35,241,030...35,267,133
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