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Gene: CDC25A (cell division cycle 25A) Homo sapiens
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Symbol: CDC25A
Name: cell division cycle 25A
Description: Exhibits chaperone binding activity and protein kinase binding activity. Involved in cellular response to UV. Predicted to localize to the cytoplasm and nucleus. Implicated in cervical cancer; prostate cancer; and urinary bladder cancer. Biomarker of autosomal recessive polycystic kidney disease; breast carcinoma; and vulva squamous cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CDC25 isoform A1-CAG; CDC25A2; CDC25A2-CAG isoform; dual specificity phosphatase CDC25A; M-phase inducer phosphatase 1
Orthologs:
Mus musculus (house mouse) : Cdc25a (cell division cycle 25A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdc25a (cell division cycle 25A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdc25a (cell division cycle 25A)
Pan paniscus (bonobo/pygmy chimpanzee) : CDC25A (cell division cycle 25A)
Canis lupus familiaris (dog) : CDC25A (cell division cycle 25A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdc25a (cell division cycle 25A)
Sus scrofa (pig) : CDC25A (cell division cycle 25A)
Chlorocebus sabaeus (green monkey) : CDC25A (cell division cycle 25A)
Heterocephalus glaber (naked mole-rat) : Cdc25a (cell division cycle 25A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl348,157,146 - 48,188,417 (-)Ensembl
GRCh38348,157,146 - 48,188,417 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37348,198,668 - 48,230,153 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36348,173,672 - 48,204,805 (-)NCBINCBI36hg18NCBI36
Build 34348,173,671 - 48,204,805NCBI
Celera348,147,668 - 48,178,797 (-)NCBI
Cytogenetic Map3p21.31NCBI
HuRef348,253,008 - 48,284,141 (-)NCBIHuRef
CHM1_1348,150,488 - 48,181,619 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CDC25A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731492
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.