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Gene: CACNB1 (calcium voltage-gated channel auxiliary subunit beta 1) Homo sapiens
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Symbol: CACNB1
Name: calcium voltage-gated channel auxiliary subunit beta 1
Description: The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CAB1; CACNLB1; calcium channel voltage-dependent subunit beta 1; calcium channel, L type, beta 1 polypeptide; calcium channel, voltage-dependent, beta 1 subunit; CCHLB1; dihydropyridine-sensitive L-type, calcium channel beta-1 subunit; MGC41896; voltage-dependent L-type calcium channel subunit beta-1
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381739,173,456 - 39,197,703 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371737,329,709 - 37,353,956 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361734,583,235 - 34,607,427 (-)NCBINCBI36hg18NCBI36
Build 341734,586,914 - 34,607,427NCBI
Celera1733,990,617 - 34,014,805 (-)NCBI
Cytogenetic Map17q12NCBI
HuRef1733,125,170 - 33,149,131 (-)NCBIHuRef
CHM1_11737,565,987 - 37,590,231 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
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Genomics

Comparative Map Data
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Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CACNB1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68552
Created: 2001-07-11
Species: Homo sapiens
Last Modified: 2019-08-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.