IL17RB (interleukin 17 receptor B)

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Gene: IL17RB (interleukin 17 receptor B) Homo sapiens

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Symbol:

IL17RB

Name:

interleukin 17 receptor B

RGD ID:

1322830

HGNC Page

HGNC:18015

Description:

Predicted to enable interleukin-17 receptor activity. Predicted to be involved in defense response. Predicted to act upstream of or within positive regulation of inflammatory response; positive regulation of interleukin-13 production; and positive regulation of interleukin-5 production. Located in intracellular membrane-bounded organelle and plasma membrane.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

CRL4; cytokine receptor CRL4; cytokine receptor-like 4; EVI27; IL-17 receptor B; IL-17 receptor homolog 1; IL-17B receptor; IL-17RB; IL-17Rh1; IL17BR; IL17RH1; interleukin 17 receptor homolog 1; interleukin 17B receptor; interleukin-17 receptor B; interleukin-17B receptor; MGC5245

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Mus musculus (house mouse):	Il17rb (interleukin 17 receptor B)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):	Il17rb (interleukin 17 receptor B)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Chinchilla lanigera (long-tailed chinchilla):	Il17rb (interleukin 17 receptor B)	NCBI	Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):	IL17RB (interleukin 17 receptor B)	NCBI	Ortholog
Canis lupus familiaris (dog):	IL17RB (interleukin 17 receptor B)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Il17rb (interleukin 17 receptor B)	NCBI	Ortholog
Sus scrofa (pig):	IL17RB (interleukin 17 receptor B)	HGNC	Ensembl, Inparanoid, NCBI, OrthoDB
Chlorocebus sabaeus (green monkey):	IL17RB (interleukin 17 receptor B)	NCBI	Ortholog
Heterocephalus glaber (naked mole-rat):	Il17rb (interleukin 17 receptor B)	NCBI	Ortholog
Other homologs ²
Rattus norvegicus (Norway rat):	Tpd52 (tumor protein D52)	HGNC	OMA
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Il17rb (interleukin 17 receptor B)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Il17rb (interleukin 17 receptor B)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ilcr-1	Alliance	DIOPT (Ensembl Compara\|PANTHER)

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	53,846,568 - 53,865,794 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	53,846,568 - 53,865,794 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	53,880,595 - 53,899,821 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	53,855,617 - 53,874,867 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	53,855,611 - 53,874,866	NCBI
Celera	3	53,847,857 - 53,867,109 (+)	NCBI		Celera
Cytogenetic Map	3	p21.1	NCBI
HuRef	3	53,929,093 - 53,948,345 (+)	NCBI		HuRef
CHM1_1	3	53,832,215 - 53,851,465 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	53,879,806 - 53,899,034 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

asthma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (ISO)

(-)-demecolcine (EXP)

(1->4)-beta-D-glucan (ISO)

17beta-estradiol (EXP,ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (ISO)

2,3-dimethoxynaphthalene-1,4-dione (EXP)

2,4,6-trinitrotoluene (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

4,4'-sulfonyldiphenol (ISO)

4-amino-2,6-dinitrotoluene (ISO)

4-hydroxyphenyl retinamide (ISO)

acetamide (ISO)

acrylamide (ISO)

all-trans-retinoic acid (EXP)

alpha-Zearalanol (ISO)

belinostat (EXP)

benzo[a]pyrene (EXP)

beta-lapachone (EXP)

bisphenol A (EXP,ISO)

bromobenzene (ISO)

Butylparaben (EXP)

cadmium dichloride (ISO)

calcitriol (EXP)

capecitabine (EXP)

carbon nanotube (ISO)

CGP 52608 (EXP)

choline (ISO)

chromium atom (EXP)

cisplatin (EXP)

copper(II) sulfate (EXP)

coumestrol (EXP)

cyclosporin A (EXP,ISO)

dichloroacetic acid (ISO)

dioxygen (EXP)

doxifluridine (EXP)

entinostat (EXP)

epoxiconazole (ISO)

ethyl methanesulfonate (EXP)

fenofibrate (ISO)

ferulic acid (ISO)

folic acid (ISO)

formaldehyde (EXP)

fulvestrant (EXP)

genistein (ISO)

ibuprofen (ISO)

imiquimod (ISO)

inulin (ISO)

L-methionine (ISO)

mercury atom (EXP)

mercury(0) (EXP)

metformin (ISO)

methotrexate (EXP)

methyl methanesulfonate (EXP)

methylparaben (EXP)

N-nitrosodimethylamine (EXP)

orphenadrine (ISO)

paclitaxel (EXP)

paracetamol (EXP,ISO)

paraquat (ISO)

PCB138 (ISO)

perfluorononanoic acid (EXP)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

pirinixic acid (ISO)

potassium dichromate (EXP)

progesterone (EXP)

quercetin (EXP)

resveratrol (EXP)

rotenone (ISO)

sirolimus (EXP)

sunitinib (EXP)

temozolomide (EXP)

testosterone (EXP)

tetrachloromethane (ISO)

thioacetamide (ISO)

titanium dioxide (ISO)

trichloroethene (ISO)

tris(2-butoxyethyl) phosphate (EXP)

troglitazone (EXP,ISO)

valproic acid (EXP)

vincristine (EXP)

zoledronic acid (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cytokine-mediated signaling pathway (IEA)

defense response (TAS)

positive regulation of inflammatory response (ISO)

positive regulation of interleukin-13 production (ISO)

positive regulation of interleukin-5 production (ISO)

regulation of cell growth (NAS)

Cellular Component

cell surface (ISO)

cytoplasm (ISO)

extracellular region (IEA)

intracellular membrane-bounded organelle (IDA)

membrane (NAS)

plasma membrane (IDA,IEA,TAS)

Molecular Function

cytokine receptor activity (NAS)

interleukin-17 receptor activity (IBA,IEA)

protein binding (IPI)

References

References - curated

#	Reference Title	Reference Citation
1.	Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation.	Beale J, etal., Sci Transl Med. 2014 Oct 1;6(256):256ra134. doi: 10.1126/scitranslmed.3009124.
2.	GOAs Human GO annotations	GOA_HUMAN data from the GO Consortium
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10748240	PMID:10749887	PMID:10815801	PMID:11058597	PMID:12477932	PMID:12975309	PMID:14759258	PMID:15340161	PMID:15489334	PMID:16344560	PMID:16609001	PMID:16609019
PMID:17008703	PMID:17453342	PMID:17975144	PMID:18794098	PMID:19118269	PMID:19913121	PMID:20237496	PMID:20453000	PMID:20545698	PMID:20628086	PMID:20800603	PMID:21252617
PMID:21473777	PMID:21570719	PMID:21873635	PMID:21988832	PMID:22070932	PMID:23497539	PMID:23851503	PMID:24120361	PMID:24144296	PMID:24247484	PMID:25732306	PMID:26285835
PMID:26728744	PMID:26990986	PMID:27000993	PMID:27113764	PMID:27146881	PMID:27906959	PMID:27979026	PMID:28132739	PMID:28160754	PMID:28421819	PMID:28514442	PMID:28715683
PMID:29496538	PMID:29729704	PMID:30649446	PMID:30945288	PMID:31182574	PMID:31585811	PMID:32948804	PMID:33455090	PMID:33649532	PMID:33658352	PMID:33961781	PMID:34065512
PMID:34251884	PMID:34264790	PMID:35271311	PMID:35487060	PMID:37448179	PMID:38600236	PMID:39010112

Genomics

Comparative Map Data

IL17RB
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	53,846,568 - 53,865,794 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	53,846,568 - 53,865,794 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	53,880,595 - 53,899,821 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	53,855,617 - 53,874,867 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	53,855,611 - 53,874,866	NCBI
Celera	3	53,847,857 - 53,867,109 (+)	NCBI		Celera
Cytogenetic Map	3	p21.1	NCBI
HuRef	3	53,929,093 - 53,948,345 (+)	NCBI		HuRef
CHM1_1	3	53,832,215 - 53,851,465 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	53,879,806 - 53,899,034 (+)	NCBI		T2T-CHM13v2.0

Il17rb
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	29,718,125 - 29,730,853 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	29,718,092 - 29,730,853 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	29,996,168 - 30,008,896 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	29,996,135 - 30,008,896 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	30,809,354 - 30,822,082 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	28,825,177 - 28,837,905 (-)	NCBI		MGSCv36	mm8
Celera	14	26,252,000 - 26,264,728 (-)	NCBI		Celera
Cytogenetic Map	14	A3	NCBI
cM Map	14	18.39	NCBI

Il17rb
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	5,186,961 - 5,200,657 (-)	NCBI		GRCr8
mRatBN7.2	16	5,180,431 - 5,194,125 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	5,180,432 - 5,194,125 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	5,193,466 - 5,206,194 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	6,338,893 - 6,351,621 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	5,190,924 - 5,203,601 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	6,064,287 - 6,077,978 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	6,064,288 - 6,077,978 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	5,995,417 - 6,009,258 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	5,335,806 - 5,349,160 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	5,336,257 - 5,349,060 (-)	NCBI
Celera	16	9,990,138 - 10,002,819 (+)	NCBI		Celera
Cytogenetic Map	16	p16	NCBI

Il17rb
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955430	3,831,667 - 3,846,788 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955430	3,831,665 - 3,847,366 (+)	NCBI	ChiLan1.0	ChiLan1.0

IL17RB
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	53,838,419 - 53,857,342 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	53,843,189 - 53,862,452 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	53,784,489 - 53,803,834 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	55,005,499 - 55,024,763 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	55,005,499 - 55,024,763 (+)	Ensembl	panpan1.1		panPan2

IL17RB
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	36,135,620 - 36,148,923 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	36,135,619 - 36,148,490 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	36,072,450 - 36,088,222 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	36,409,271 - 36,425,054 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	36,409,273 - 36,422,761 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	35,850,966 - 35,866,696 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	36,209,575 - 36,225,340 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	36,427,027 - 36,442,862 (-)	NCBI		UU_Cfam_GSD_1.0

Il17rb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	171,373,656 - 171,387,513 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936473	4,512,510 - 4,524,236 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936473	4,512,461 - 4,524,452 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IL17RB
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	35,948,340 - 35,963,944 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	35,948,248 - 35,963,191 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	39,018,874 - 39,033,934 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IL17RB
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	15,229,020 - 15,249,145 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	15,229,053 - 15,248,437 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	151,642,007 - 151,662,350 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Il17rb
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624822	3,337,940 - 3,355,199 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624822	3,339,236 - 3,355,278 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in IL17RB
29 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 3p21.31-14.3(chr3:49461000-55314500)x1	copy number loss	See cases [RCV000051511]	Chr3:49461000..55314500 [GRCh38] Chr3:49498433..55348528 [GRCh37] Chr3:49473437..55323568 [NCBI36] Chr3:3p21.31-14.3	pathogenic
GRCh38/hg38 3p21.1-14.3(chr3:53287477-57025368)x1	copy number loss	See cases [RCV000053929]	Chr3:53287477..57025368 [GRCh38] Chr3:53321495..57059396 [GRCh37] Chr3:53296535..57034436 [NCBI36] Chr3:3p21.1-14.3	uncertain significance
GRCh38/hg38 3p21.2-14.3(chr3:51394434-55064449)x1	copy number loss	See cases [RCV000143631]	Chr3:51394434..55064449 [GRCh38] Chr3:51431865..55098476 [GRCh37] Chr3:51406905..55073516 [NCBI36] Chr3:3p21.2-14.3	likely pathogenic
GRCh37/hg19 3p21.2-14.2(chr3:52086599-59689209)x1	copy number loss	See cases [RCV000239886]	Chr3:52086599..59689209 [GRCh37] Chr3:3p21.2-14.2	pathogenic
NM_018725.4(IL17RB):c.173C>G (p.Ala58Gly)	single nucleotide variant	not specified [RCV004313582]	Chr3:53849742 [GRCh38] Chr3:53883769 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.649A>G (p.Ile217Val)	single nucleotide variant	not specified [RCV004297240]	Chr3:53856963 [GRCh38] Chr3:53890990 [GRCh37] Chr3:3p21.1	uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)	copy number gain	See cases [RCV000512358]	Chr3:61892..197851986 [GRCh37] Chr3:3p26.3-q29	pathogenic
GRCh37/hg19 3p21.1(chr3:53892719-54182466)x3	copy number gain	not provided [RCV000682258]	Chr3:53892719..54182466 [GRCh37] Chr3:3p21.1	likely benign
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3	copy number gain	not provided [RCV000742138]	Chr3:61495..197838262 [GRCh37] Chr3:3p26.3-q29	pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3	copy number gain	See cases [RCV000511055]	Chr3:61892..197851986 [GRCh37] Chr3:3p26.3-q29	pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3	copy number gain	not provided [RCV000742133]	Chr3:60174..197948027 [GRCh37] Chr3:3p26.3-q29	pathogenic
GRCh37/hg19 3p21.1(chr3:53413246-53955646)x3	copy number gain	not provided [RCV000847484]	Chr3:53413246..53955646 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.146G>A (p.Arg49Gln)	single nucleotide variant	not provided [RCV004692718]\|not specified [RCV001733700]	Chr3:53849715 [GRCh38] Chr3:53883742 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.1414G>A (p.Ala472Thr)	single nucleotide variant	not specified [RCV004148080]	Chr3:53865213 [GRCh38] Chr3:53899240 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.826G>A (p.Val276Ile)	single nucleotide variant	not specified [RCV004182324]	Chr3:53858797 [GRCh38] Chr3:53892824 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.1226G>A (p.Gly409Asp)	single nucleotide variant	not specified [RCV004206710]	Chr3:53865025 [GRCh38] Chr3:53899052 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.1127T>C (p.Met376Thr)	single nucleotide variant	not specified [RCV004246560]	Chr3:53864926 [GRCh38] Chr3:53898953 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.394A>G (p.Thr132Ala)	single nucleotide variant	not specified [RCV004205831]	Chr3:53852910 [GRCh38] Chr3:53886937 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.1213G>A (p.Asp405Asn)	single nucleotide variant	not specified [RCV004075708]	Chr3:53865012 [GRCh38] Chr3:53899039 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.194T>C (p.Leu65Ser)	single nucleotide variant	not specified [RCV004096744]	Chr3:53849763 [GRCh38] Chr3:53883790 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.860C>T (p.Pro287Leu)	single nucleotide variant	not specified [RCV004267862]	Chr3:53860142 [GRCh38] Chr3:53894169 [GRCh37] Chr3:3p21.1	likely benign
NM_018725.4(IL17RB):c.64G>A (p.Val22Ile)	single nucleotide variant	not specified [RCV004251375]	Chr3:53848667 [GRCh38] Chr3:53882694 [GRCh37] Chr3:3p21.1	likely benign
NM_018725.4(IL17RB):c.1366G>A (p.Asp456Asn)	single nucleotide variant	not specified [RCV004248829]	Chr3:53865165 [GRCh38] Chr3:53899192 [GRCh37] Chr3:3p21.1	likely benign
NM_018725.4(IL17RB):c.1198G>A (p.Val400Ile)	single nucleotide variant	not specified [RCV004263570]	Chr3:53864997 [GRCh38] Chr3:53899024 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.1159A>G (p.Lys387Glu)	single nucleotide variant	not specified [RCV004351425]	Chr3:53864958 [GRCh38] Chr3:53898985 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.1160A>C (p.Lys387Thr)	single nucleotide variant	not specified [RCV004351426]	Chr3:53864959 [GRCh38] Chr3:53898986 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.235C>T (p.Arg79Cys)	single nucleotide variant	not specified [RCV004350277]	Chr3:53852007 [GRCh38] Chr3:53886034 [GRCh37] Chr3:3p21.1	uncertain significance
GRCh37/hg19 3p21.2-14.2(chr3:51149374-59265315)x1	copy number loss	not specified [RCV003986409]	Chr3:51149374..59265315 [GRCh37] Chr3:3p21.2-14.2	pathogenic
GRCh37/hg19 3p21.1(chr3:53532755-54395791)x3	copy number gain	not specified [RCV003986463]	Chr3:53532755..54395791 [GRCh37] Chr3:3p21.1	uncertain significance
GRCh37/hg19 3p21.1-14.3(chr3:53659716-54500525)x3	copy number gain	not specified [RCV003986453]	Chr3:53659716..54500525 [GRCh37] Chr3:3p21.1-14.3	uncertain significance
NM_018725.4(IL17RB):c.529G>A (p.Gly177Arg)	single nucleotide variant	not provided [RCV004585258]	Chr3:53855341 [GRCh38] Chr3:53889368 [GRCh37] Chr3:3p21.1	likely benign
NM_018725.4(IL17RB):c.1344T>G (p.Phe448Leu)	single nucleotide variant	not specified [RCV004405022]	Chr3:53865143 [GRCh38] Chr3:53899170 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.236G>A (p.Arg79His)	single nucleotide variant	not specified [RCV004405023]	Chr3:53852008 [GRCh38] Chr3:53886035 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.266C>T (p.Thr89Met)	single nucleotide variant	not specified [RCV004405024]	Chr3:53852038 [GRCh38] Chr3:53886065 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.413C>A (p.Ala138Asp)	single nucleotide variant	not specified [RCV004405025]	Chr3:53852929 [GRCh38] Chr3:53886956 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.710T>C (p.Ile237Thr)	single nucleotide variant	not specified [RCV004405026]	Chr3:53857653 [GRCh38] Chr3:53891680 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.766A>G (p.Thr256Ala)	single nucleotide variant	not specified [RCV004405027]	Chr3:53858737 [GRCh38] Chr3:53892764 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.788G>A (p.Arg263Gln)	single nucleotide variant	not specified [RCV004405028]	Chr3:53858759 [GRCh38] Chr3:53892786 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.965C>T (p.Ser322Phe)	single nucleotide variant	not specified [RCV004405029]	Chr3:53864764 [GRCh38] Chr3:53898791 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.795A>T (p.Lys265Asn)	single nucleotide variant	not specified [RCV004627964]	Chr3:53858766 [GRCh38] Chr3:53892793 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.239T>C (p.Leu80Ser)	single nucleotide variant	not specified [RCV004627965]	Chr3:53852011 [GRCh38] Chr3:53886038 [GRCh37] Chr3:3p21.1	uncertain significance
NM_018725.4(IL17RB):c.1126A>G (p.Met376Val)	single nucleotide variant	not specified [RCV004213926]	Chr3:53864925 [GRCh38] Chr3:53898952 [GRCh37] Chr3:3p21.1	uncertain significance

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	388
Count of miRNA genes:	266
Interacting mature miRNAs:	280
Transcripts:	ENST00000288167, ENST00000475124, ENST00000494338
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCh38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
407249703	GWAS898679_H	vesicoureteral reflux QTL GWAS898679 (human)		0.0000002	vesicoureteral reflux		3	53850887	53850888	Human
406892673	GWAS541649_H	interleukin-17 receptor B measurement QTL GWAS541649 (human)		4e-77	interleukin-17 receptor B measurement		3	53858803	53858804	Human
407241029	GWAS890005_H	serum metabolite measurement QTL GWAS890005 (human)		0.000002	serum metabolite measurement		3	53865249	53865250	Human
1298487	BFD1_H	Body fluid distribution QTL 1 (human)	3.94		Body fluid distribution	impedance ratio	3	36380712	62380712	Human
407281281	GWAS930257_H	body height QTL GWAS930257 (human)		8e-10	body height (VT:0001253)	body height (CMO:0000106)	3	53862823	53862824	Human
1298489	RA4_H	Rheumatoid arthritis QTL 4 (human)		0.0283	Joint/bone inflammation	rheumatoid arthritis	3	36380712	62380712	Human
1643509	BW293_H	Body Weight QTL 293 (human)	1.42		Body weight	BMI	3	36380712	62380712	Human
2289308	BW392_H	Body weight QTL 392 (human)	1.42		Body weight	BMI	3	36380712	62380712	Human
1331643	COPD16_H	Chronic obstructive pulmonary disease QTL 16 (human)	1.07		Chronic airflow obstruction	post-BD FEV1 minus pre-BD FEV1/pre-BD FEV1 x 100	3	49380651	75380651	Human

Markers in Region

RH102982

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	3	53,893,126 - 53,893,253	UniSTS	GRCh37
Build 36	3	53,868,166 - 53,868,293	RGD	NCBI36
Celera	3	53,860,408 - 53,860,535	RGD
Cytogenetic Map	3	p21.1	UniSTS
HuRef	3	53,941,645 - 53,941,772	UniSTS
GeneMap99-GB4 RH Map	3	173.07	UniSTS

RH44991

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	3	53,899,800 - 53,899,899	UniSTS	GRCh37
Build 36	3	53,874,840 - 53,874,939	RGD	NCBI36
Celera	3	53,867,082 - 53,867,181	RGD
Cytogenetic Map	3	p21.1	UniSTS
HuRef	3	53,948,318 - 53,948,417	UniSTS
GeneMap99-GB4 RH Map	3	159.69	UniSTS

SHGC-35928

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	3	53,899,490 - 53,899,605	UniSTS	GRCh37
Build 36	3	53,874,530 - 53,874,645	RGD	NCBI36
Celera	3	53,866,772 - 53,866,887	RGD
Cytogenetic Map	3	p21.1	UniSTS
HuRef	3	53,948,008 - 53,948,123	UniSTS
Stanford-G3 RH Map	3	2438.0	UniSTS
GeneMap99-G3 RH Map	3	2336.0	UniSTS

RH16665

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	3	53,899,426 - 53,899,533	UniSTS	GRCh37
Build 36	3	53,874,466 - 53,874,573	RGD	NCBI36
Celera	3	53,866,708 - 53,866,815	RGD
Cytogenetic Map	3	p21.1	UniSTS
HuRef	3	53,947,944 - 53,948,051	UniSTS
GeneMap99-GB4 RH Map	3	173.17	UniSTS
NCBI RH Map	3	503.3	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	entire extraembryonic component	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	pharyngeal arch	renal system	reproductive system	respiratory system	sensory system	visual system
1204	2437	2788	2252	4960	1720	2342	6	624	1928	465	2262	7274	6446	46	3727	1	846	1740	1607	173	1

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_018725	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005265310	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005265311	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005265312	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_011533941	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017006804	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017006805	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017006806	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017006807	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_024453634	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_024453635	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_024453636	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC012467	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF208110	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF208111	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF212365	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF250309	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK307749	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AX253209	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY359122	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY518533	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC000980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BI458542	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471055	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068275	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CS135264	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DA093617	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENST00000288167 ⟹ ENSP00000288167

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	53,846,568 - 53,865,794 (+)	Ensembl

Ensembl Acc Id:

ENST00000475124

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	53,846,584 - 53,865,588 (+)	Ensembl

Ensembl Acc Id:

ENST00000494338 ⟹ ENSP00000418638

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	53,846,585 - 53,864,891 (+)	Ensembl

RefSeq Acc Id:

NM_018725 ⟹ NP_061195

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	3	53,846,568 - 53,865,794 (+)	NCBI
GRCh37	3	53,880,577 - 53,899,827 (+)	ENTREZGENE
Build 36	3	53,855,617 - 53,874,867 (+)	NCBI Archive
HuRef	3	53,929,093 - 53,948,345 (+)	ENTREZGENE
CHM1_1	3	53,832,215 - 53,851,465 (+)	NCBI
T2T-CHM13v2.0	3	53,879,806 - 53,899,034 (+)	NCBI

Sequence:

show sequence

ATCCCGCGCAGTGGCCCGGCGATGTCGCTCGTGCTGCTAAGCCTGGCCGCGCTGTGCAGGAGCG
CCGTACCCCGAGAGCCGACCGTTCAATGTGGCTCTGAAACTGGGCCATCTCCAGAGTGGATGCT
ACAACATGATCTAATCCCCGGAGACTTGAGGGACCTCCGAGTAGAACCTGTTACAACTAGTGTT
GCAACAGGGGACTATTCAATTTTGATGAATGTAAGCTGGGTACTCCGGGCAGATGCCAGCATCC
GCTTGTTGAAGGCCACCAAGATTTGTGTGACGGGCAAAAGCAACTTCCAGTCCTACAGCTGTGT
GAGGTGCAATTACACAGAGGCCTTCCAGACTCAGACCAGACCCTCTGGTGGTAAATGGACATTT
TCCTACATCGGCTTCCCTGTAGAGCTGAACACAGTCTATTTCATTGGGGCCCATAATATTCCTA
ATGCAAATATGAATGAAGATGGCCCTTCCATGTCTGTGAATTTCACCTCACCAGGCTGCCTAGA
CCACATAATGAAATATAAAAAAAAGTGTGTCAAGGCCGGAAGCCTGTGGGATCCGAACATCACT
GCTTGTAAGAAGAATGAGGAGACAGTAGAAGTGAACTTCACAACCACTCCCCTGGGAAACAGAT
ACATGGCTCTTATCCAACACAGCACTATCATCGGGTTTTCTCAGGTGTTTGAGCCACACCAGAA
GAAACAAACGCGAGCTTCAGTGGTGATTCCAGTGACTGGGGATAGTGAAGGTGCTACGGTGCAG
CTGACTCCATATTTTCCTACTTGTGGCAGCGACTGCATCCGACATAAAGGAACAGTTGTGCTCT
GCCCACAAACAGGCGTCCCTTTCCCTCTGGATAACAACAAAAGCAAGCCGGGAGGCTGGCTGCC
TCTCCTCCTGCTGTCTCTGCTGGTGGCCACATGGGTGCTGGTGGCAGGGATCTATCTAATGTGG
AGGCACGAAAGGATCAAGAAGACTTCCTTTTCTACCACCACACTACTGCCCCCCATTAAGGTTC
TTGTGGTTTACCCATCTGAAATATGTTTCCATCACACAATTTGTTACTTCACTGAATTTCTTCA
AAACCATTGCAGAAGTGAGGTCATCCTTGAAAAGTGGCAGAAAAAGAAAATAGCAGAGATGGGT
CCAGTGCAGTGGCTTGCCACTCAAAAGAAGGCAGCAGACAAAGTCGTCTTCCTTCTTTCCAATG
ACGTCAACAGTGTGTGCGATGGTACCTGTGGCAAGAGCGAGGGCAGTCCCAGTGAGAACTCTCA
AGACCTCTTCCCCCTTGCCTTTAACCTTTTCTGCAGTGATCTAAGAAGCCAGATTCATCTGCAC
AAATACGTGGTGGTCTACTTTAGAGAGATTGATACAAAAGACGATTACAATGCTCTCAGTGTCT
GCCCCAAGTACCACCTCATGAAGGATGCCACTGCTTTCTGTGCAGAACTTCTCCATGTCAAGCA
GCAGGTGTCAGCAGGAAAAAGATCACAAGCCTGCCACGATGGCTGCTGCTCCTTGTAGCCCACC
CATGAGAAGCAAGAGACCTTAAAGGCTTCCTATCCCACCAATTACAGGGAAAAAACGTGTGATG
ATCCTGAAGCTTACTATGCAGCCTACAAACAGCCTTAGTAATTAAAACATTTTATACCAATAAA
ATTTTCAAATATTGCTAACTAATGTAGCATTAACTAACGATTGGAAACTACATTTACAACTTCA
AAGCTGTTTTATACATAGAAATCAATTACAGTTTTAATTGAAAACTATAACCATTTTGATAATG
CAACAATAAAGCATCTTCAGCCAAACATCTAGTCTTCCATAGACCATGCATTGCAGTGTACCCA
GAACTGTTTAGCTAATATTCTATGTTTAATTAATGAATACTAACTCTAAGAACCCCTCACTGAT
TCACTCAATAGCATCTTAAGTGAAAAACCTTCTATTACATGCAAAAAATCATTGTTTTTAAGAT
AACAAAAGTAGGGAATAAACAAGCTGAACCCA

hide sequence

Protein Sequences


Protein RefSeqs	NP_061195	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAF78776	(Get FASTA)	NCBI Sequence Viewer
	AAF86051	(Get FASTA)	NCBI Sequence Viewer
	AAF86052	(Get FASTA)	NCBI Sequence Viewer
	AAH00980	(Get FASTA)	NCBI Sequence Viewer
	AAK37428	(Get FASTA)	NCBI Sequence Viewer
	AAQ89956	(Get FASTA)	NCBI Sequence Viewer
	AAR89910	(Get FASTA)	NCBI Sequence Viewer
	CAC93839	(Get FASTA)	NCBI Sequence Viewer
	CAJ21520	(Get FASTA)	NCBI Sequence Viewer
	EAW65298	(Get FASTA)	NCBI Sequence Viewer
	EAW65299	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000288167
	ENSP00000288167.3
	ENSP00000418638.1
GenBank Protein	Q9NRM6	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_061195 ⟸ NM_018725
- Peptide Label:	precursor
- UniProtKB:	Q9NRL4 (UniProtKB/Swiss-Prot), Q9BPZ0 (UniProtKB/Swiss-Prot), Q9NRM5 (UniProtKB/Swiss-Prot), Q9NRM6 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MSLVLLSLAALCRSAVPREPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATGDYSI LMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWTFSYIGFPV ELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLWDPNITACKKNEE TVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVTGDSEGATVQLTPYFPT CGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLPLLLLSLLVATWVLVAGIYLMWRHERIKK TSFSTTTLLPPIKVLVVYPSEICFHHTICYFTEFLQNHCRSEVILEKWQKKKIAEMGPVQWLAT QKKAADKVVFLLSNDVNSVCDGTCGKSEGSPSENSQDLFPLAFNLFCSDLRSQIHLHKYVVVYF REIDTKDDYNALSVCPKYHLMKDATAFCAELLHVKQQVSAGKRSQACHDGCCSL hide sequence

Ensembl Acc Id:

ENSP00000418638 ⟸ ENST00000494338

Ensembl Acc Id:

ENSP00000288167 ⟸ ENST00000288167

Protein Domains

Interleukin-17 receptor fibronectin-III-like SEFIR

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9NRM6-F1-model_v2	AlphaFold	Q9NRM6	1-502	view protein structure

Promoters

RGD ID:

6864746

Promoter ID:

EPDNEW_H5538

Type:

initiation region

Name:

IL17RB_1

Description:

interleukin 17 receptor B

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.; Paired-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	3	53,846,568 - 53,846,628	EPDNEW

RGD ID:

6801152

Promoter ID:

HG_KWN:45297

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

CD4+TCell, HeLa_S3, K562, Lymphoblastoid

Transcripts:

NM_018397, NM_018725

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	3	53,854,226 - 53,855,692 (+)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:18015	AgrOrtholog
COSMIC	IL17RB	COSMIC
Ensembl Genes	ENSG00000056736	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENST00000288167	ENTREZGENE
	ENST00000288167.8	UniProtKB/Swiss-Prot
	ENST00000494338.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.2150	UniProtKB/Swiss-Prot
	2.60.40.2160	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.40.50.11530	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx	ENSG00000056736	GTEx
HGNC ID	HGNC:18015	ENTREZGENE
Human Proteome Map	IL17RB	Human Proteome Map
InterPro	IL-17_rcpt-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IL17R_fnIII_D1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IL17RA/B_FnIII-like_1_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IL17RA/B_FnIII-like_2_sf	UniProtKB/Swiss-Prot
	SEFIR_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	hsa:55540	UniProtKB/Swiss-Prot
NCBI Gene	55540	ENTREZGENE
OMIM	605458	OMIM
PANTHER	INTERLEUKIN-17 RECEPTOR B	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR15583	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	IL17R_fnIII_D1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IL17R_fnIII_D2	UniProtKB/Swiss-Prot
	SEFIR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB	PA29796	PharmGKB
PROSITE	SEFIR	UniProtKB/Swiss-Prot
UniProt	C9IZN0_HUMAN	UniProtKB/TrEMBL
	I17RB_HUMAN	UniProtKB/Swiss-Prot
	Q9BPZ0	ENTREZGENE
	Q9NRL4	ENTREZGENE
	Q9NRM5	ENTREZGENE
	Q9NRM6	ENTREZGENE
UniProt Secondary	Q9BPZ0	UniProtKB/Swiss-Prot
	Q9NRL4	UniProtKB/Swiss-Prot
	Q9NRM5	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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