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Gene: CACNA1D (calcium voltage-gated channel subunit alpha1 D) Homo sapiens
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Symbol: CACNA1D
Name: calcium voltage-gated channel subunit alpha1 D
RGD ID: 735457
Description: Exhibits alpha-actinin binding activity and voltage-gated calcium channel activity involved SA node cell action potential. Contributes to high voltage-gated calcium channel activity. Involved in several processes, including calcium ion import; cardiac conduction; and cardiac muscle cell action potential involved in contraction. Localizes to L-type voltage-gated calcium channel complex. Implicated in type 2 diabetes mellitus. Biomarker of type 2 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CACH3; CACN4; CACNL1A2; calcium channel, L type, alpha-1 polypeptide; calcium channel, L type, alpha-1 polypeptide, isoform 2; calcium channel, neuroendocrine/brain-type, alpha 1 subunit; calcium channel, voltage-dependent, L type, alpha 1D subunit; Cav1.3; CCHL1A2; PASNA; SANDD; voltage-dependent L-type calcium channel subunit alpha-1D; voltage-gated calcium channel alpha 1 subunit; voltage-gated calcium channel alpha subunit Cav1.3; voltage-gated calcium channel subunit alpha Cav1.3
Orthologs:
Mus musculus (house mouse) : Cacna1d (calcium channel, voltage-dependent, L type, alpha 1D subunit)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cacna1d (calcium voltage-gated channel subunit alpha1 D)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cacna1d (calcium voltage-gated channel subunit alpha1 D)
Pan paniscus (bonobo/pygmy chimpanzee) : CACNA1D (calcium voltage-gated channel subunit alpha1 D)
Canis lupus familiaris (dog) : CACNA1D (calcium voltage-gated channel subunit alpha1 D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cacna1d (calcium voltage-gated channel subunit alpha1 D)
Sus scrofa (pig) : CACNA1D (calcium voltage-gated channel subunit alpha1 D)
Chlorocebus sabaeus (African green monkey) : CACNA1D (calcium voltage-gated channel subunit alpha1 D)
Heterocephalus glaber (naked mole-rat) : Cacna1d (calcium voltage-gated channel subunit alpha1 D)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl353,328,963 - 53,813,733 (+)EnsemblGRCh38hg38GRCh38
GRCh38353,494,611 - 53,813,733 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37353,529,076 - 53,847,179 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36353,504,116 - 53,821,001 (+)NCBINCBI36hg18NCBI36
Build 34353,504,115 - 53,821,001NCBI
Celera353,496,179 - 53,813,773 (+)NCBI
Cytogenetic Map3p21.1NCBI
HuRef353,577,566 - 53,895,012 (+)NCBIHuRef
CHM1_1353,480,800 - 53,798,135 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

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Nomenclature History
 
More on CACNA1D
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735457
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-09-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.