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Gene: NRXN1 (neurexin 1) Homo sapiens
Symbol: NRXN1
Name: neurexin 1
Description: Exhibits type 1 fibroblast growth factor receptor binding activity. Involved in several processes, including positive regulation of protein phosphorylation; positive regulation of signal transduction; and regulation of gene expression. Localizes to cell surface; nucleolus; and plasma membrane. Implicated in Pitt-Hopkins-like syndrome 2.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp313P2036; FLJ35941; Hs.22998; KIAA0578; neurexin I; neurexin I-alpha; neurexin I-beta; neurexin-1; neurexin-1-alpha; neurexin-1-beta; PTHSL2; SCZD17
Mus musculus (house mouse) : Nrxn1 (neurexin I)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nrxn1 (neurexin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nrxn1 (neurexin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NRXN1 (neurexin 1)
Canis lupus familiaris (dog) : NRXN1 (neurexin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nrxn1 (neurexin 1)
Sus scrofa (pig) : NRXN1 (neurexin 1)
Chlorocebus sabaeus (African green monkey) : NRXN1 (neurexin 1)
Heterocephalus glaber (naked mole-rat) : Nrxn1 (neurexin 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl249,918,503 - 51,225,575 (-)EnsemblGRCh38hg38GRCh38
GRCh38249,918,503 - 51,032,536 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37250,145,643 - 51,259,674 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36250,000,992 - 51,113,178 (-)NCBINCBI36hg18NCBI36
Build 34250,059,138 - 50,486,545NCBI
Celera249,985,850 - 51,099,841 (-)NCBI
Cytogenetic Map2p16.3NCBI
HuRef249,879,094 - 50,994,141 (-)NCBIHuRef
CHM1_1250,076,197 - 51,190,490 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences