Gene: CACNA1G (calcium voltage-gated channel subunit alpha1 G) Homo sapiens
Symbol: CACNA1G
Name: calcium voltage-gated channel subunit alpha1 G
Description: Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Ca(V)T.1; calcium channel, voltage-dependent, alpha 1G subunit; calcium channel, voltage-dependent, T type, alpha 1G subunit; calcium channel, voltage-dependent, T type, alpha-1G subunit; Cav3.1; cav3.1c; MGC117234; NBR13; OTTHUMP00000221509; OTTHUMP00000221510; OTTHUMP00000221511; OTTHUMP00000221512; OTTHUMP00000221513; OTTHUMP00000221514; OTTHUMP00000221515; OTTHUMP00000221516; OTTHUMP00000221517; OTTHUMP00000221518; OTTHUMP00000221560; OTTHUMP00000221561; OTTHUMP00000221562; OTTHUMP00000221563; OTTHUMP00000221564; OTTHUMP00000221565; OTTHUMP00000221566; OTTHUMP00000221567; OTTHUMP00000221568; OTTHUMP00000221569; OTTHUMP00000221570; OTTHUMP00000221572; OTTHUMP00000221573; OTTHUMP00000221574; OTTHUMP00000221575; OTTHUMP00000221590; OTTHUMP00000221591; OTTHUMP00000221592; OTTHUMP00000221593; OTTHUMP00000221594; SCA42; SCA42ND; voltage-dependent calcium channel alpha 1G subunit, isoform 11; voltage-dependent T-type calcium channel alpha 1G subunit; voltage-dependent T-type calcium channel subunit alpha-1G; voltage-gated calcium channel subunit alpha Cav3.1
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381750,560,933 - 50,629,625 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371748,638,429 - 48,704,835 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361745,993,448 - 46,059,541 (+)NCBINCBI36hg18NCBI36
Build 341745,993,447 - 46,038,832NCBI
Celera1745,099,811 - 45,165,917 (+)NCBI
Cytogenetic Map17q21.33NCBI
HuRef1744,006,381 - 44,072,836 (+)NCBIHuRef
CHM1_11748,702,306 - 48,768,826 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
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References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CACNA1G
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68989
Created: 2001-11-06
Species: Homo sapiens
Last Modified: 2019-03-05
Status: ACTIVE