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Gene: DPP6 (dipeptidyl peptidase like 6) Homo sapiens
Symbol: DPP6
Name: dipeptidyl peptidase like 6
Description: Exhibits potassium channel regulator activity. Involved in regulation of potassium ion transmembrane transport. Localizes to the voltage-gated potassium channel complex. Implicated in amyotrophic lateral sclerosis; autosomal dominant non-syndromic intellectual disability 33; and spinal muscular atrophy.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dipeptidyl aminopeptidase IV-related protein; dipeptidyl aminopeptidase-like protein 6; dipeptidyl aminopeptidase-related protein; dipeptidyl peptidase 6; dipeptidyl peptidase IV-like protein; dipeptidyl peptidase IV-related protein; dipeptidyl peptidase VI; dipeptidyl-peptidase 6; dipeptidylpeptidase 6; dipeptidylpeptidase VI; DPL1; DPP VI; DPPX; FLJ55680; MGC46605; MRD33; VF2
Mus musculus (house mouse) : Dpp6 (dipeptidylpeptidase 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dpp6 (dipeptidyl peptidase like 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dpp6 (dipeptidyl peptidase like 6)
Pan paniscus (bonobo/pygmy chimpanzee) : DPP6 (dipeptidyl peptidase like 6)
Canis lupus familiaris (dog) : DPP6 (dipeptidyl peptidase like 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dpp6 (dipeptidyl peptidase like 6)
Sus scrofa (pig) : DPP6 (dipeptidyl peptidase like 6)
Chlorocebus sabaeus (green monkey) : DPP6 (dipeptidyl peptidase like 6)
Heterocephalus glaber (naked mole-rat) : Dpp6 (dipeptidyl peptidase like 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl7153,887,097 - 154,894,285 (+)Ensembl
GRCh387153,748,133 - 154,894,285 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377153,584,419 - 154,264,025 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh377154,400,205 - 154,685,995 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367154,060,464 - 154,316,928 (+)NCBINCBI36hg18NCBI36
Build 367153,380,710 - 153,894,933 (+)NCBINCBI36hg18NCBI36
Build 347153,867,178 - 154,122,809NCBI
Celera7148,524,570 - 149,103,154 (+)NCBI
Celera7148,318,756 - 148,319,129 (-)NCBI
Cytogenetic Map7q36.2NCBI
HuRef7147,386,496 - 147,386,897 (+)NCBIHuRef
HuRef7148,164,313 - 148,419,023 (+)NCBIHuRef
HuRef7147,843,601 - 148,104,076 (+)NCBIHuRef
CHM1_17153,592,654 - 154,692,523 (+)NCBICHM1_1
CRA_TCAGchr7v27152,913,032 - 153,914,021 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DPP6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68590
Created: 2001-07-11
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.