SULT1E1 (sulfotransferase family 1E member 1) - Rat Genome Database

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Gene: SULT1E1 (sulfotransferase family 1E member 1) Homo sapiens
Analyze
Symbol: SULT1E1
Name: sulfotransferase family 1E member 1
RGD ID: 1351097
HGNC Page HGNC:11377
Description: Enables flavonol 3-sulfotransferase activity and steroid sulfotransferase activity. Involved in several processes, including 3'-phosphoadenosine 5'-phosphosulfate metabolic process; estrogen catabolic process; and ethanol catabolic process. Acts upstream of or within sulfation. Located in cytosol and nuclear membrane. Implicated in breast cancer and endometrial cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: EST; EST-1; estrogen sulfotransferase; estrone sulfotransferase; MGC34459; ST1E1; STE; sulfotransferase 1E1; sulfotransferase family 1E, estrogen-preferring, member 1; sulfotransferase, estrogen-preferring
RGD Orthologs
Mouse
Rat
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38469,821,122 - 69,860,145 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl469,841,212 - 69,860,145 (-)EnsemblGRCh38hg38GRCh38
GRCh37470,706,930 - 70,725,863 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36470,741,519 - 70,760,459 (-)NCBINCBI36Build 36hg18NCBI36
Build 34470,887,690 - 70,906,630NCBI
Celera468,060,253 - 68,079,193 (-)NCBICelera
Cytogenetic Map4q13.3NCBI
HuRef466,504,780 - 66,523,720 (-)NCBIHuRef
CHM1_1470,743,366 - 70,762,280 (-)NCBICHM1_1
T2T-CHM13v2.0473,176,039 - 73,194,989 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
(S)-ropivacaine  (EXP)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1-Hydroxypyrene  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-acetamidofluorene  (ISO)
2-hydroxy-17beta-estradiol  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP,ISO)
3-chloropropane-1,2-diol  (ISO)
3-Hydroxybenzo[a]pyrene  (EXP)
3-methylcholanthrene  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4-nitrophenol  (EXP)
4-nonylphenol  (EXP)
acetonitrile  (EXP)
adenosine 3',5'-bismonophosphate  (EXP)
aflatoxin B1  (EXP)
Aloe emodin  (EXP)
alpha-Zearalanol  (ISO)
ammonium chloride  (ISO)
antimonite  (EXP)
apigenin  (EXP)
Aroclor 1254  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
avobenzone  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene-7,8-dione  (EXP)
beta-naphthoflavone  (EXP)
bifenthrin  (ISO)
biochanin A  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bosentan  (EXP)
butylated hydroxyanisole  (ISO)
Butylparaben  (ISO)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
chenodeoxycholic acid  (EXP)
choline  (ISO)
chrysin  (EXP)
clofibrate  (ISO)
clofibric acid  (ISO)
colforsin daropate hydrochloride  (EXP)
copper(II) chloride  (EXP)
coumarin  (ISO)
cyanocob(III)alamin  (ISO)
dehydroepiandrosterone  (EXP)
dexamethasone  (ISO)
dextran sulfate  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
dienestrol  (EXP)
diethylstilbestrol  (EXP)
difenoconazole  (ISO)
dioxygen  (EXP,ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (EXP)
diuron  (ISO)
doxorubicin  (EXP)
endosulfan  (EXP,ISO)
estriol  (EXP)
estrone  (EXP)
estrone 3-sulfate  (ISO)
ethanol  (EXP,ISO)
fenofibrate  (ISO)
fipronil  (EXP)
folic acid  (EXP,ISO)
fulvestrant  (ISO)
furan  (ISO)
genistein  (EXP,ISO)
glafenine  (ISO)
glycine betaine  (ISO)
glyphosate  (ISO)
graphene oxide  (ISO)
Heliotrine  (EXP)
hexachlorobenzene  (ISO)
hexestrol  (EXP)
hydrogen peroxide  (ISO)
ibuprofen  (EXP,ISO)
indole-3-methanol  (ISO)
ketoconazole  (ISO)
kojic acid  (ISO)
L-methionine  (ISO)
lead diacetate  (EXP)
lipopolysaccharide  (EXP,ISO)
meclofenamic acid  (EXP)
methotrexate  (EXP)
mifepristone  (EXP)
N,N-diethyl-m-toluamide  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
N-nitrosomorpholine  (ISO)
N-Nitrosopyrrolidine  (EXP)
nickel atom  (EXP)
O-methyleugenol  (EXP)
orphenadrine  (ISO)
paracetamol  (EXP,ISO)
perfluorodecanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (EXP,ISO)
pirinixic acid  (EXP,ISO)
pravastatin  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (EXP)
propiconazole  (ISO)
Propiverine  (ISO)
quercetin  (EXP)
resveratrol  (EXP)
rifampicin  (EXP)
rotenone  (ISO)
senecionine  (EXP)
Senkirkine  (EXP)
silicon dioxide  (EXP)
sodium arsenite  (EXP,ISO)
sodium dodecyl sulfate  (EXP)
sulindac  (EXP,ISO)
sunitinib  (EXP)
tebuconazole  (EXP)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
triadimefon  (EXP)
triclosan  (EXP)
tris(2-butoxyethyl) phosphate  (EXP)
tris(2-chloroethyl) phosphate  (EXP)
urethane  (EXP)
valproic acid  (ISO)
vitamin E  (ISO)
zaragozic acid A  (ISO)
zearalenone  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA)
cytosol  (IDA,IEA,TAS)
nuclear membrane  (IDA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Genetic polymorphisms of SULT1A1 and SULT1E1 and the risk and survival of breast cancer. Choi JY, etal., Cancer Epidemiol Biomarkers Prev. 2005 May;14(5):1090-5.
2. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
3. CYP1A1, SULT1A1, and SULT1E1 polymorphisms are risk factors for endometrial cancer susceptibility. Hirata H, etal., Cancer. 2008 May 1;112(9):1964-73.
4. Metabolism and disposition of acetaminophen: recent advances in relation to hepatotoxicity and diagnosis. McGill MR and Jaeschke H, Pharm Res. 2013 Sep;30(9):2174-87. doi: 10.1007/s11095-013-1007-6. Epub 2013 Mar 6.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
7. Steroid sulfatase: a pivotal player in estrogen synthesis and metabolism. Purohit A, etal., Mol Cell Endocrinol. 2011 Jul 4;340(2):154-60. Epub 2011 Jun 30.
8. Pairwise combinations of estrogen metabolism genotypes in postmenopausal breast cancer etiology. Rebbeck TR, etal., Cancer Epidemiol Biomarkers Prev. 2007 Mar;16(3):444-50.
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Increased estrogen sulfation of estradiol 17beta-D-glucuronide in metastatic tumor rat livers. Sun H, etal., J Pharmacol Exp Ther. 2006 Nov;319(2):818-31. Epub 2006 Aug 8.
11. Identification and preliminary validation of novel biomarkers of acute hepatic ischaemia/reperfusion injury using dual-platform proteomic/degradomic approaches. Svetlov SI, etal., Biomarkers. 2006 Jul-Aug;11(4):355-69.
Additional References at PubMed
PMID:7779757   PMID:7961757   PMID:8185618   PMID:8530066   PMID:8603401   PMID:8971138   PMID:9034160   PMID:9348232   PMID:10541560   PMID:10720750   PMID:11154739   PMID:11535246  
PMID:11688987   PMID:11884392   PMID:12477932   PMID:12782487   PMID:14507642   PMID:14556660   PMID:15188402   PMID:15355916   PMID:15489334   PMID:16169070   PMID:16189514   PMID:16418064  
PMID:16969590   PMID:16985250   PMID:17187396   PMID:17293380   PMID:17425406   PMID:17661084   PMID:18029348   PMID:18467089   PMID:18794126   PMID:18794456   PMID:18831980   PMID:19343046  
PMID:19429440   PMID:19548878   PMID:19551860   PMID:19776291   PMID:19898482   PMID:20025931   PMID:20056724   PMID:20142249   PMID:20214802   PMID:20379614   PMID:20381444   PMID:20429582  
PMID:20505544   PMID:21073915   PMID:21543429   PMID:21548389   PMID:21764778   PMID:21828262   PMID:21873635   PMID:22197379   PMID:22380844   PMID:23207770   PMID:23384540   PMID:23736977  
PMID:24039991   PMID:24481480   PMID:24567372   PMID:25416956   PMID:25819444   PMID:26169578   PMID:26344197   PMID:26458420   PMID:26542807   PMID:26723541   PMID:27150425   PMID:27854074  
PMID:29436390   PMID:29929982   PMID:30217785   PMID:32296183   PMID:33064293   PMID:33665770   PMID:34857952   PMID:35059953   PMID:37724676  


Genomics

Comparative Map Data
SULT1E1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38469,821,122 - 69,860,145 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl469,841,212 - 69,860,145 (-)EnsemblGRCh38hg38GRCh38
GRCh37470,706,930 - 70,725,863 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36470,741,519 - 70,760,459 (-)NCBINCBI36Build 36hg18NCBI36
Build 34470,887,690 - 70,906,630NCBI
Celera468,060,253 - 68,079,193 (-)NCBICelera
Cytogenetic Map4q13.3NCBI
HuRef466,504,780 - 66,523,720 (-)NCBIHuRef
CHM1_1470,743,366 - 70,762,280 (-)NCBICHM1_1
T2T-CHM13v2.0473,176,039 - 73,194,989 (-)NCBIT2T-CHM13v2.0
Sult1e1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39587,723,827 - 87,739,470 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl587,723,828 - 87,739,453 (-)EnsemblGRCm39 Ensembl
GRCm38587,575,968 - 87,591,611 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl587,575,969 - 87,591,594 (-)EnsemblGRCm38mm10GRCm38
MGSCv37588,004,993 - 88,020,636 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36588,650,530 - 88,666,155 (-)NCBIMGSCv36mm8
Celera584,792,542 - 84,808,207 (-)NCBICelera
Cytogenetic Map5E1NCBI
cM Map543.56NCBI
Sult1e1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81420,700,444 - 20,718,719 (+)NCBIGRCr8
mRatBN7.21420,422,324 - 20,439,562 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1420,422,324 - 20,439,275 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1420,610,541 - 20,627,768 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01421,929,454 - 21,946,681 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01420,684,867 - 20,702,117 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01422,070,861 - 22,089,264 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1422,072,024 - 22,089,248 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01421,985,847 - 22,004,150 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1419,831,652 - 19,842,299 (+)NCBICelera
Cytogenetic Map14p21NCBI
SULT1E1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2360,230,334 - 60,249,862 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1460,433,324 - 60,452,868 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0454,377,681 - 54,396,619 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1460,714,305 - 60,733,229 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl460,713,392 - 60,733,229 (+)Ensemblpanpan1.1panPan2
LOC482182
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11359,323,430 - 59,343,745 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1359,052,730 - 59,072,999 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01360,119,719 - 60,140,008 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1360,120,936 - 60,140,217 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11359,734,248 - 59,754,528 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01359,195,062 - 59,214,797 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01360,339,614 - 60,359,890 (-)NCBIUU_Cfam_GSD_1.0
SULT1E1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl866,811,550 - 66,834,473 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1866,811,536 - 66,838,181 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SULT1E1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1718,313,510 - 18,330,768 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl718,313,238 - 18,330,741 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660844,599,800 - 4,616,560 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in SULT1E1
14 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 4q13.2-13.3(chr4:66842408-70831557)x1 copy number loss See cases [RCV000050704] Chr4:66842408..70831557 [GRCh38]
Chr4:67708126..71697274 [GRCh37]
Chr4:67390721..71916138 [NCBI36]
Chr4:4q13.2-13.3		 pathogenic
GRCh38/hg38 4q13.2-13.3(chr4:68852530-69850009)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051599]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051599]|See cases [RCV000051599] Chr4:68852530..69850009 [GRCh38]
Chr4:69718248..70715727 [GRCh37]
Chr4:4q13.2-13.3		 uncertain significance|conflicting data from submitters
GRCh38/hg38 4q12-22.3(chr4:51831622-97505618)x3 copy number gain See cases [RCV000051772] Chr4:51831622..97505618 [GRCh38]
Chr4:52697788..98426769 [GRCh37]
Chr4:52392545..98645792 [NCBI36]
Chr4:4q12-22.3		 pathogenic
GRCh38/hg38 4q13.2-21.23(chr4:67869564-85517308)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053294]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053294]|See cases [RCV000053294] Chr4:67869564..85517308 [GRCh38]
Chr4:68735282..86438461 [GRCh37]
Chr4:68417877..86657485 [NCBI36]
Chr4:4q13.2-21.23		 pathogenic
GRCh38/hg38 4q13.1-13.3(chr4:65454562-72313693)x1 copy number loss See cases [RCV000053293] Chr4:65454562..72313693 [GRCh38]
Chr4:66320280..73179410 [GRCh37]
Chr4:66002875..73398274 [NCBI36]
Chr4:4q13.1-13.3		 pathogenic
GRCh38/hg38 4q13.3(chr4:69758599-70193037)x1 copy number loss See cases [RCV000054041] Chr4:69758599..70193037 [GRCh38]
Chr4:70624317..71058754 [GRCh37]
Chr4:70658906..71093343 [NCBI36]
Chr4:4q13.3		 uncertain significance
GRCh38/hg38 4q13.2-13.3(chr4:68902161-70620273)x3 copy number gain See cases [RCV000136751] Chr4:68902161..70620273 [GRCh38]
Chr4:69767879..71485990 [GRCh37]
Chr4:69802468..71520579 [NCBI36]
Chr4:4q13.2-13.3		 pathogenic
GRCh38/hg38 4q13.2-13.3(chr4:67799665-74240920)x1 copy number loss See cases [RCV000137622] Chr4:67799665..74240920 [GRCh38]
Chr4:68665383..75106637 [GRCh37]
Chr4:68347978..75325501 [NCBI36]
Chr4:4q13.2-13.3		 likely pathogenic
GRCh38/hg38 4q13.2-13.3(chr4:68796335-69850009)x3 copy number gain See cases [RCV000140868] Chr4:68796335..69850009 [GRCh38]
Chr4:69662053..70715727 [GRCh37]
Chr4:69696642..70750316 [NCBI36]
Chr4:4q13.2-13.3		 uncertain significance
GRCh38/hg38 4q13.2-13.3(chr4:67744481-70267689)x1 copy number loss See cases [RCV000142366] Chr4:67744481..70267689 [GRCh38]
Chr4:68610199..71133406 [GRCh37]
Chr4:68292794..71167995 [NCBI36]
Chr4:4q13.2-13.3		 uncertain significance
GRCh38/hg38 4q13.2-13.3(chr4:68799852-69853815)x3 copy number gain See cases [RCV000143121] Chr4:68799852..69853815 [GRCh38]
Chr4:69665570..70719533 [GRCh37]
Chr4:69700159..70754122 [NCBI36]
Chr4:4q13.2-13.3		 uncertain significance
GRCh38/hg38 4q13.2-22.3(chr4:68686088-95294456)x3 copy number gain See cases [RCV000143458] Chr4:68686088..95294456 [GRCh38]
Chr4:69551806..96215607 [GRCh37]
Chr4:69234401..96434630 [NCBI36]
Chr4:4q13.2-22.3		 pathogenic
GRCh38/hg38 4q13.2-13.3(chr4:68852530-69850009)x3 copy number gain See cases [RCV000148108] Chr4:68852530..69850009 [GRCh38]
Chr4:69718248..70715727 [GRCh37]
Chr4:69752837..70750316 [NCBI36]
Chr4:4q13.2-13.3		 conflicting interpretations of pathogenicity|uncertain significance|conflicting data from submitters
GRCh37/hg19 4p16.3-q35.2(chr4:12440-190904441)x3 copy number gain See cases [RCV000446653] Chr4:12440..190904441 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4q13.1-21.1(chr4:66017575-76772947)x1 copy number loss See cases [RCV000510445] Chr4:66017575..76772947 [GRCh37]
Chr4:4q13.1-21.1		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473) copy number gain See cases [RCV000510453] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473)x3 copy number gain See cases [RCV000512241] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4q13.1-13.3(chr4:64705501-73469716)x3 copy number gain not provided [RCV000682409] Chr4:64705501..73469716 [GRCh37]
Chr4:4q13.1-13.3		 pathogenic
GRCh37/hg19 4q13.2-13.3(chr4:70012338-71167321)x3 copy number gain not provided [RCV000682416] Chr4:70012338..71167321 [GRCh37]
Chr4:4q13.2-13.3		 uncertain significance
GRCh37/hg19 4q13.3(chr4:70594519-70885440)x3 copy number gain not provided [RCV000682417] Chr4:70594519..70885440 [GRCh37]
Chr4:4q13.3		 uncertain significance
GRCh37/hg19 4q13.3(chr4:70725002-71237421)x3 copy number gain not provided [RCV000682418] Chr4:70725002..71237421 [GRCh37]
Chr4:4q13.3		 likely benign
GRCh37/hg19 4q12-13.3(chr4:58332294-71587615)x1 copy number loss not provided [RCV000743602] Chr4:58332294..71587615 [GRCh37]
Chr4:4q12-13.3		 pathogenic
GRCh37/hg19 4q13.3(chr4:70587338-70729266)x3 copy number gain not provided [RCV000743693] Chr4:70587338..70729266 [GRCh37]
Chr4:4q13.3		 benign
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190915650)x3 copy number gain not provided [RCV000743155] Chr4:49450..190915650 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190963766)x3 copy number gain not provided [RCV000743156] Chr4:49450..190963766 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:11525-191028879)x3 copy number gain not provided [RCV000743147] Chr4:11525..191028879 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
NM_005420.3(SULT1E1):c.229C>A (p.Arg77=) single nucleotide variant not provided [RCV000900358] Chr4:69855343 [GRCh38]
Chr4:70721061 [GRCh37]
Chr4:4q13.3		 benign
NM_005420.3(SULT1E1):c.459C>T (p.Ser153=) single nucleotide variant not provided [RCV000970111] Chr4:69849474 [GRCh38]
Chr4:70715192 [GRCh37]
Chr4:4q13.3		 benign
GRCh37/hg19 4q13.2-21.22(chr4:68242784-82991431)x3 copy number gain not provided [RCV000845944] Chr4:68242784..82991431 [GRCh37]
Chr4:4q13.2-21.22		 pathogenic
GRCh37/hg19 4q13.3(chr4:70618421-71083238)x1 copy number loss not provided [RCV001005554] Chr4:70618421..71083238 [GRCh37]
Chr4:4q13.3		 uncertain significance
NM_005420.3(SULT1E1):c.498T>A (p.Val166=) single nucleotide variant not provided [RCV000935367] Chr4:69847791 [GRCh38]
Chr4:70713509 [GRCh37]
Chr4:4q13.3		 likely benign
GRCh37/hg19 4q13.2-21.21(chr4:68950363-79738598)x1 copy number loss not provided [RCV001005553] Chr4:68950363..79738598 [GRCh37]
Chr4:4q13.2-21.21		 pathogenic
GRCh38/hg38 4q12-21.1(chr4:51891814-76009719)x1 copy number loss Piebaldism [RCV001420508] Chr4:51891814..76009719 [GRCh38]
Chr4:4q12-21.1		 pathogenic
NM_005420.3(SULT1E1):c.305G>A (p.Arg102Lys) single nucleotide variant not specified [RCV004137058] Chr4:69854281 [GRCh38]
Chr4:70719999 [GRCh37]
Chr4:4q13.3		 uncertain significance
NC_000004.12:g.67833055_82716065del deletion See cases [RCV003313802] Chr4:67833055..82716065 [GRCh38]
Chr4:4q13.2-21.22		 pathogenic
GRCh37/hg19 4q13.1-13.3(chr4:61867555-74711517) copy number loss not specified [RCV002053422] Chr4:61867555..74711517 [GRCh37]
Chr4:4q13.1-13.3		 pathogenic
GRCh37/hg19 4q12-31.21(chr4:52866944-143582507)x3 copy number gain not provided [RCV001827738] Chr4:52866944..143582507 [GRCh37]
Chr4:4q12-31.21		 pathogenic
NM_005420.3(SULT1E1):c.763A>G (p.Met255Val) single nucleotide variant not specified [RCV004327672] Chr4:69844170 [GRCh38]
Chr4:70709888 [GRCh37]
Chr4:4q13.3		 uncertain significance
GRCh37/hg19 4q13.2-13.3(chr4:69661413-70724847)x3 copy number gain not provided [RCV002473840] Chr4:69661413..70724847 [GRCh37]
Chr4:4q13.2-13.3		 uncertain significance
GRCh37/hg19 4q13.2-13.3(chr4:70478978-70985189)x1 copy number loss not provided [RCV002473768] Chr4:70478978..70985189 [GRCh37]
Chr4:4q13.2-13.3		 uncertain significance
NM_005420.3(SULT1E1):c.104C>G (p.Ala35Gly) single nucleotide variant not specified [RCV004228996] Chr4:69857541 [GRCh38]
Chr4:70723259 [GRCh37]
Chr4:4q13.3		 uncertain significance
GRCh37/hg19 4q13.2-13.3(chr4:70479061-70985189)x1 copy number loss not provided [RCV002475802] Chr4:70479061..70985189 [GRCh37]
Chr4:4q13.2-13.3		 uncertain significance
NM_005420.3(SULT1E1):c.673C>T (p.His225Tyr) single nucleotide variant not specified [RCV004097064] Chr4:69844260 [GRCh38]
Chr4:70709978 [GRCh37]
Chr4:4q13.3		 uncertain significance
NM_005420.3(SULT1E1):c.214G>A (p.Asp72Asn) single nucleotide variant not specified [RCV004109344] Chr4:69855358 [GRCh38]
Chr4:70721076 [GRCh37]
Chr4:4q13.3		 uncertain significance
NM_005420.3(SULT1E1):c.619A>G (p.Ile207Val) single nucleotide variant not specified [RCV004204824] Chr4:69844314 [GRCh38]
Chr4:70710032 [GRCh37]
Chr4:4q13.3		 uncertain significance
NM_005420.3(SULT1E1):c.448A>G (p.Asn150Asp) single nucleotide variant not specified [RCV004135723] Chr4:69849485 [GRCh38]
Chr4:70715203 [GRCh37]
Chr4:4q13.3		 likely benign
NM_005420.3(SULT1E1):c.580G>T (p.Asp194Tyr) single nucleotide variant not specified [RCV004164775] Chr4:69847709 [GRCh38]
Chr4:70713427 [GRCh37]
Chr4:4q13.3		 uncertain significance
NM_005420.3(SULT1E1):c.572T>C (p.Phe191Ser) single nucleotide variant not specified [RCV004072332] Chr4:69847717 [GRCh38]
Chr4:70713435 [GRCh37]
Chr4:4q13.3		 uncertain significance
NM_005420.3(SULT1E1):c.364T>G (p.Cys122Gly) single nucleotide variant not specified [RCV004280378] Chr4:69854222 [GRCh38]
Chr4:70719940 [GRCh37]
Chr4:4q13.3		 uncertain significance
NM_005420.3(SULT1E1):c.282A>C (p.Gln94His) single nucleotide variant not specified [RCV004336874] Chr4:69854304 [GRCh38]
Chr4:70720022 [GRCh37]
Chr4:4q13.3		 uncertain significance
GRCh37/hg19 4q12-13.3(chr4:57584845-72430996)x1 copy number loss not provided [RCV003485417] Chr4:57584845..72430996 [GRCh37]
Chr4:4q12-13.3		 pathogenic
GRCh37/hg19 4q13.2-13.3(chr4:69146217-75500577)x1 copy number loss not provided [RCV003485422] Chr4:69146217..75500577 [GRCh37]
Chr4:4q13.2-13.3		 pathogenic
GRCh37/hg19 4q13.1-13.3(chr4:63684557-71480358)x3 copy number gain not provided [RCV003484182] Chr4:63684557..71480358 [GRCh37]
Chr4:4q13.1-13.3		 pathogenic
GRCh37/hg19 4q13.3(chr4:70563498-71253752)x1 copy number loss not specified [RCV003986514] Chr4:70563498..71253752 [GRCh37]
Chr4:4q13.3		 uncertain significance
GRCh37/hg19 4p12-q35.2(chr4:45455621-191003541)x3 copy number gain not provided [RCV003885507] Chr4:45455621..191003541 [GRCh37]
Chr4:4p12-q35.2		 pathogenic
NM_005420.3(SULT1E1):c.52C>A (p.Leu18Ile) single nucleotide variant not specified [RCV004461018] Chr4:69857593 [GRCh38]
Chr4:70723311 [GRCh37]
Chr4:4q13.3		 uncertain significance
NM_005420.3(SULT1E1):c.388A>C (p.Asn130His) single nucleotide variant not specified [RCV004461016] Chr4:69849545 [GRCh38]
Chr4:70715263 [GRCh37]
Chr4:4q13.3		 uncertain significance
NM_005420.3(SULT1E1):c.407T>C (p.Val136Ala) single nucleotide variant not specified [RCV004461017] Chr4:69849526 [GRCh38]
Chr4:70715244 [GRCh37]
Chr4:4q13.3		 uncertain significance
NM_005420.3(SULT1E1):c.107G>C (p.Arg36Thr) single nucleotide variant not specified [RCV004668340] Chr4:69857538 [GRCh38]
Chr4:70723256 [GRCh37]
Chr4:4q13.3		 uncertain significance
NM_005420.3(SULT1E1):c.767G>C (p.Arg256Thr) single nucleotide variant not specified [RCV004668342] Chr4:69844166 [GRCh38]
Chr4:70709884 [GRCh37]
Chr4:4q13.3		 uncertain significance
NM_005420.3(SULT1E1):c.347C>T (p.Ser116Leu) single nucleotide variant not specified [RCV004668341] Chr4:69854239 [GRCh38]
Chr4:70719957 [GRCh37]
Chr4:4q13.3		 uncertain significance
NM_005420.3(SULT1E1):c.415T>C (p.Tyr139His) single nucleotide variant not specified [RCV004668343] Chr4:69849518 [GRCh38]
Chr4:70715236 [GRCh37]
Chr4:4q13.3		 uncertain significance
NM_005420.3(SULT1E1):c.756G>A (p.Ser252=) single nucleotide variant not specified [RCV004681751] Chr4:69844177 [GRCh38]
Chr4:70709895 [GRCh37]
Chr4:4q13.3		 likely benign
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR199A1hsa-miR-199a-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23060436

Predicted Target Of
Summary Value
Count of predictions:568
Count of miRNA genes:415
Interacting mature miRNAs:438
Transcripts:ENST00000226444, ENST00000504002, ENST00000506796
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407001219GWAS650195_Hsex hormone-binding globulin measurement QTL GWAS650195 (human)1e-08sex hormone-binding globulin measurement46985973869859739Human
407033297GWAS682273_Hheel bone mineral density QTL GWAS682273 (human)2e-09heel bone mineral densitybone mineral density (CMO:0001226)46985855269858553Human
406918812GWAS567788_Hheel bone mineral density QTL GWAS567788 (human)2e-10heel bone mineral densitybone mineral density (CMO:0001226)46985855269858553Human
407003583GWAS652559_Hsex hormone-binding globulin measurement QTL GWAS652559 (human)0.000002sex hormone-binding globulin measurement46985973869859739Human
406934030GWAS583006_Hheel bone mineral density QTL GWAS583006 (human)4e-10heel bone mineral densitybone mineral density (CMO:0001226)46985855269858553Human

Markers in Region
SHGC-10625  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37470,719,600 - 70,719,776UniSTSGRCh37
Build 36470,754,189 - 70,754,365RGDNCBI36
Celera468,072,923 - 68,073,099RGD
Cytogenetic Map4q13.1UniSTS
HuRef466,517,449 - 66,517,625UniSTS
TNG Radiation Hybrid Map438636.0UniSTS
SHGC-67359  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37470,706,978 - 70,707,136UniSTSGRCh37
Build 36470,741,567 - 70,741,725RGDNCBI36
Celera468,060,301 - 68,060,459RGD
Cytogenetic Map4q13.1UniSTS
HuRef466,504,828 - 66,504,986UniSTS
TNG Radiation Hybrid Map4180.0UniSTS
GeneMap99-GB4 RH Map4420.29UniSTS
RH71211  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37470,707,292 - 70,707,433UniSTSGRCh37
Build 36470,741,881 - 70,742,022RGDNCBI36
Celera468,060,615 - 68,060,756RGD
Cytogenetic Map4q13.1UniSTS
HuRef466,505,142 - 66,505,283UniSTS
GeneMap99-GB4 RH Map4420.4UniSTS
NCBI RH Map4817.2UniSTS
SULT1E1_8653  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37470,706,901 - 70,707,807UniSTSGRCh37
Build 36470,741,490 - 70,742,396RGDNCBI36
Celera468,060,224 - 68,061,130RGD
HuRef466,504,751 - 66,505,657UniSTS
SHGC-67307  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15q22.3UniSTS
Cytogenetic Map20q13.3UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map7p13UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map3q21.2UniSTS
Cytogenetic Map3p21.3UniSTS
Cytogenetic Map18q11.2UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic MapXp11.3UniSTS
Cytogenetic Map7q21.2UniSTS
Cytogenetic Map13q14UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map18pter-p11.3UniSTS
Cytogenetic Map7p22.2UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map4q13.1UniSTS
Cytogenetic Map6p25UniSTS
Cytogenetic Map13q34UniSTS
Cytogenetic Map8q24.22UniSTS
Cytogenetic Map16q21UniSTS
Cytogenetic Map1p35.2UniSTS
Cytogenetic Map1q25.1UniSTS
Cytogenetic Map12q13.3UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map8q21.1UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map1p13.3UniSTS
Cytogenetic Map6q22.31UniSTS
Cytogenetic Map7p11.2UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map12q24.23UniSTS
Cytogenetic Map9p13.3UniSTS
Cytogenetic Map3p21.1UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map2q24.2UniSTS
Cytogenetic Map2p25.1-p24.1UniSTS
Cytogenetic Map5q32UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map16q22.2UniSTS
Cytogenetic Map1q32.2-q41UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map14q12UniSTS
Cytogenetic Map16q24.3UniSTS
Cytogenetic Map17q24.1UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map16p13UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic MapXp22.3UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map6p22.3UniSTS
Cytogenetic Map6p25.2UniSTS
Cytogenetic Map14q22.1UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map7p15.3UniSTS
Cytogenetic Map1q25.3UniSTS
Cytogenetic Map15q22.2UniSTS
Cytogenetic Map20q12UniSTS
Cytogenetic Map4p15.32UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map12q24.13UniSTS
Cytogenetic Map20q11.22UniSTS
Cytogenetic Map6p12.3UniSTS
Cytogenetic Map7q33UniSTS
Cytogenetic Map15q13.2UniSTS
Cytogenetic Map8q22.1UniSTS
Cytogenetic Map17q21UniSTS
Cytogenetic Map22q11.1UniSTS
Cytogenetic Map7q22UniSTS
Cytogenetic Map6q21UniSTS
Cytogenetic Map1p36.13UniSTS
Cytogenetic Map5p13.3UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map4q26UniSTS
Cytogenetic Map10q11.23UniSTS
Cytogenetic Map16p13.12UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map16q23.1UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map15q15.3UniSTS
Cytogenetic Map2q35UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map18q21.32UniSTS
Cytogenetic Map5q22.1UniSTS
Cytogenetic Map1p36.12UniSTS
Cytogenetic Map14q32.12UniSTS
Cytogenetic Map12q13UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map14q32.31UniSTS
Cytogenetic Map17q21.2UniSTS
Cytogenetic Map11q13.5UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map22q12.1UniSTS
Cytogenetic Map7p14.3UniSTS
Cytogenetic Map20q13.33UniSTS
Cytogenetic Map1p36.21UniSTS
TNG Radiation Hybrid Map41213.0UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
750 1658 1949 1575 3155 1267 1768 4 597 857 441 1800 4606 3990 26 1968 720 1518 1071 169 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_005420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011532210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047416100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047416101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054350751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054350752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007057952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC108941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH006624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK310845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK312236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY436634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC027956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR407621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS691411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S77383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U08098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U55764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y11195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000226444   ⟹   ENSP00000226444
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl469,841,212 - 69,860,145 (-)Ensembl
Ensembl Acc Id: ENST00000504002
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl469,849,126 - 69,860,145 (-)Ensembl
RefSeq Acc Id: NM_005420   ⟹   NP_005411
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38469,841,212 - 69,860,145 (-)NCBI
GRCh37470,706,930 - 70,725,870 (-)ENTREZGENE
Build 36470,741,519 - 70,760,459 (-)NCBI Archive
HuRef466,504,780 - 66,523,720 (-)ENTREZGENE
CHM1_1470,743,366 - 70,762,280 (-)NCBI
T2T-CHM13v2.0473,176,039 - 73,194,973 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011532210   ⟹   XP_011530512
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38469,847,717 - 69,860,145 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047416100   ⟹   XP_047272056
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38469,841,212 - 69,860,145 (-)NCBI
RefSeq Acc Id: XM_047416101   ⟹   XP_047272057
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38469,841,212 - 69,860,145 (-)NCBI
RefSeq Acc Id: XM_054350751   ⟹   XP_054206726
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0473,176,039 - 73,194,989 (-)NCBI
RefSeq Acc Id: XM_054350752   ⟹   XP_054206727
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0473,182,544 - 73,194,973 (-)NCBI
RefSeq Acc Id: XR_007057952
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38469,821,122 - 69,860,145 (-)NCBI
RefSeq Acc Id: NP_005411   ⟸   NM_005420
- UniProtKB: Q8N6X5 (UniProtKB/Swiss-Prot),   P49888 (UniProtKB/Swiss-Prot),   Q53X91 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011530512   ⟸   XM_011532210
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSP00000226444   ⟸   ENST00000226444
RefSeq Acc Id: XP_047272057   ⟸   XM_047416101
- Peptide Label: isoform X1
- UniProtKB: P49888 (UniProtKB/Swiss-Prot),   Q8N6X5 (UniProtKB/Swiss-Prot),   Q53X91 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047272056   ⟸   XM_047416100
- Peptide Label: isoform X1
- UniProtKB: P49888 (UniProtKB/Swiss-Prot),   Q8N6X5 (UniProtKB/Swiss-Prot),   Q53X91 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054206726   ⟸   XM_054350751
- Peptide Label: isoform X1
- UniProtKB: Q8N6X5 (UniProtKB/Swiss-Prot),   P49888 (UniProtKB/Swiss-Prot),   Q53X91 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054206727   ⟸   XM_054350752
- Peptide Label: isoform X2
Protein Domains
Sulfotransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P49888-F1-model_v2 AlphaFold P49888 1-294 view protein structure

Promoters
RGD ID:6867614
Promoter ID:EPDNEW_H6972
Type:multiple initiation site
Name:SULT1E1_1
Description:sulfotransferase family 1E member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38469,860,145 - 69,860,205EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:11377 AgrOrtholog
COSMIC SULT1E1 COSMIC
Ensembl Genes ENSG00000109193 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000226444 ENTREZGENE
  ENST00000226444.4 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000109193 GTEx
HGNC ID HGNC:11377 ENTREZGENE
Human Proteome Map SULT1E1 Human Proteome Map
InterPro P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sulfotransferase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:6783 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 6783 ENTREZGENE
OMIM 600043 OMIM
PANTHER SULFOTRANSFERASE 1E1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SULFOTRANSFERASE SULT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Sulfotransfer_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA340 PharmGKB, RGD
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt P49888 ENTREZGENE
  Q53X91 ENTREZGENE, UniProtKB/TrEMBL
  Q8N6X5 ENTREZGENE
  ST1E1_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary Q8N6X5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-10 SULT1E1  sulfotransferase family 1E member 1  SULT1E1  sulfotransferase family 1E, estrogen-preferring, member 1  Symbol and/or name change 5135510 APPROVED