CACNB3 (calcium voltage-gated channel auxiliary subunit beta 3) - Rat Genome Database

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Gene: CACNB3 (calcium voltage-gated channel auxiliary subunit beta 3) Homo sapiens
Analyze
Symbol: CACNB3
Name: calcium voltage-gated channel auxiliary subunit beta 3
RGD ID: 735859
HGNC Page HGNC
Description: Contributes to voltage-gated calcium channel activity. Involved in calcium ion transport. Located in membrane. Part of voltage-gated calcium channel complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CAB3; CACNLB3; calcium channel voltage-dependent subunit beta 3; calcium channel, voltage-dependent, beta 3 subunit; FLJ58949; voltage-dependent L-type calcium channel subunit beta-3
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1248,813,794 - 48,828,941 (+)EnsemblGRCh38hg38GRCh38
GRCh381248,814,432 - 48,828,941 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371249,208,263 - 49,222,724 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361247,498,779 - 47,508,991 (+)NCBINCBI36hg18NCBI36
Build 341247,498,778 - 47,508,991NCBI
Celera1248,008,638 - 48,018,850 (+)NCBI
Cytogenetic Map12q13.12NCBI
HuRef1246,241,454 - 46,255,965 (+)NCBIHuRef
CHM1_11249,174,031 - 49,188,542 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:7557998   PMID:8119293   PMID:8494331   PMID:8617257   PMID:8621722   PMID:8825650   PMID:11160515   PMID:12181424   PMID:12477932   PMID:14702039   PMID:15028279   PMID:15170217  
PMID:15489334   PMID:16344560   PMID:16525042   PMID:18535142   PMID:19807924   PMID:19917615   PMID:21873635   PMID:21926972   PMID:25527503   PMID:26186194   PMID:26760575   PMID:28514442  
PMID:28611215   PMID:31462068   PMID:32296183  


Genomics

Comparative Map Data
CACNB3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1248,813,794 - 48,828,941 (+)EnsemblGRCh38hg38GRCh38
GRCh381248,814,432 - 48,828,941 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371249,208,263 - 49,222,724 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361247,498,779 - 47,508,991 (+)NCBINCBI36hg18NCBI36
Build 341247,498,778 - 47,508,991NCBI
Celera1248,008,638 - 48,018,850 (+)NCBI
Cytogenetic Map12q13.12NCBI
HuRef1246,241,454 - 46,255,965 (+)NCBIHuRef
CHM1_11249,174,031 - 49,188,542 (+)NCBICHM1_1
Cacnb3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391598,526,317 - 98,542,417 (+)NCBIGRCm39mm39
GRCm39 Ensembl1598,528,721 - 98,542,410 (+)Ensembl
GRCm381598,628,436 - 98,644,536 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1598,630,840 - 98,644,529 (+)EnsemblGRCm38mm10GRCm38
MGSCv371598,462,651 - 98,474,961 (+)NCBIGRCm37mm9NCBIm37
MGSCv361598,463,139 - 98,472,563 (+)NCBImm8
Celera15100,780,822 - 100,793,130 (+)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1554.64NCBI
Cacnb3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27129,784,799 - 129,797,074 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl7129,783,674 - 129,797,074 (+)Ensembl
Rnor_6.07140,311,120 - 140,324,902 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7140,315,368 - 140,324,902 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X114,814,959 - 114,828,180 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47137,384,752 - 137,394,283 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17137,461,187 - 137,470,720 (+)NCBI
Celera7126,277,809 - 126,287,303 (+)NCBICelera
Cytogenetic Map7q36NCBI
Cacnb3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555007,672,828 - 7,687,420 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555007,676,331 - 7,685,174 (+)NCBIChiLan1.0ChiLan1.0
CACNB3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11240,797,293 - 40,811,409 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1240,797,293 - 40,811,409 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01239,918,022 - 39,931,386 (-)NCBIMhudiblu_PPA_v0panPan3
CACNB3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1275,705,587 - 5,714,620 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl275,706,064 - 5,717,647 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2740,539,137 - 40,552,356 (+)NCBI
ROS_Cfam_1.0275,756,425 - 5,769,646 (-)NCBI
UMICH_Zoey_3.1275,720,277 - 5,733,496 (-)NCBI
UNSW_CanFamBas_1.0275,710,377 - 5,723,584 (-)NCBI
UU_Cfam_GSD_1.02740,931,388 - 40,944,607 (+)NCBI
Cacnb3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494566,498,659 - 66,511,978 (-)NCBI
SpeTri2.0NW_0049365126,652,836 - 6,666,171 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CACNB3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl514,874,238 - 14,888,224 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1514,875,524 - 14,888,224 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2515,172,444 - 15,182,010 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CACNB3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11145,056,116 - 45,071,076 (+)NCBI
ChlSab1.1 Ensembl1145,061,046 - 45,071,544 (+)Ensembl
Vero_WHO_p1.0NW_023666037201,075,907 - 201,090,442 (-)NCBI
Cacnb3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248163,334,934 - 3,348,355 (-)NCBI

Position Markers
WI-18779  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371249,221,887 - 49,222,033UniSTSGRCh37
Build 361247,508,154 - 47,508,300RGDNCBI36
Celera1248,018,013 - 48,018,159RGD
Cytogenetic Map12q13UniSTS
HuRef1246,255,126 - 46,255,272UniSTS
GeneMap99-GB4 RH Map12217.17UniSTS
Whitehead-RH Map12305.1UniSTS
D12S2032  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371249,222,019 - 49,222,359UniSTSGRCh37
Build 361247,508,286 - 47,508,626RGDNCBI36
Celera1248,018,145 - 48,018,485RGD
Cytogenetic Map12q13UniSTS
HuRef1246,255,258 - 46,255,598UniSTS
GeneMap99-GB4 RH Map12217.28UniSTS
Whitehead-RH Map12309.3UniSTS
Whitehead-YAC Contig Map12 UniSTS
CACNB3_499  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371249,221,904 - 49,222,722UniSTSGRCh37
Build 361247,508,171 - 47,508,989RGDNCBI36
Celera1248,018,030 - 48,018,848RGD
HuRef1246,255,143 - 46,255,961UniSTS
IB1472  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371249,222,507 - 49,222,671UniSTSGRCh37
Build 361247,508,774 - 47,508,938RGDNCBI36
Celera1248,018,633 - 48,018,797RGD
Cytogenetic Map12q13UniSTS
HuRef1246,255,746 - 46,255,910UniSTS
GeneMap99-GB4 RH Map12217.33UniSTS
Whitehead-RH Map12310.2UniSTS
NCBI RH Map12391.9UniSTS
MARC_42832-42833:1097693526:1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371249,218,683 - 49,219,236UniSTSGRCh37
Celera1248,014,809 - 48,015,362UniSTS
HuRef1246,251,922 - 46,252,475UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:9834
Count of miRNA genes:1195
Interacting mature miRNAs:1581
Transcripts:ENST00000301050, ENST00000536187, ENST00000540990, ENST00000547230, ENST00000547392, ENST00000547693, ENST00000547818, ENST00000548279, ENST00000548860, ENST00000548874, ENST00000549226, ENST00000549971, ENST00000550064, ENST00000550168, ENST00000550190, ENST00000550391, ENST00000550483, ENST00000550771, ENST00000551544, ENST00000551716, ENST00000552022, ENST00000552465, ENST00000552480, ENST00000552812
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1919 981 809 142 198 23 2357 916 3004 143 1152 1209 125 644 1499
Low 519 1869 797 363 1554 323 1994 1271 723 275 307 402 49 1 560 1283 4 2
Below cutoff 1 139 120 119 198 119 6 9 7 1 1 2 6 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_030048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_000725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011538727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011538728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017019957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024449180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024449181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001748867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001748868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC117498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK122911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK289709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK297639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK300901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK304537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK316323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL534844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL537072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL702978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC041811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI667991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD013906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D43704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB277524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L27584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U07139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X76555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X76556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000301050   ⟹   ENSP00000301050
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,818,496 - 48,828,941 (+)Ensembl
RefSeq Acc Id: ENST00000536187   ⟹   ENSP00000444160
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,815,587 - 48,828,219 (+)Ensembl
RefSeq Acc Id: ENST00000540990   ⟹   ENSP00000445495
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,814,451 - 48,828,200 (+)Ensembl
RefSeq Acc Id: ENST00000547230   ⟹   ENSP00000448304
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,818,909 - 48,828,941 (+)Ensembl
RefSeq Acc Id: ENST00000547392   ⟹   ENSP00000446529
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,818,504 - 48,828,336 (+)Ensembl
RefSeq Acc Id: ENST00000547693
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,813,794 - 48,823,984 (+)Ensembl
RefSeq Acc Id: ENST00000547818   ⟹   ENSP00000448137
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,818,484 - 48,826,518 (+)Ensembl
RefSeq Acc Id: ENST00000548279   ⟹   ENSP00000449497
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,818,787 - 48,824,697 (+)Ensembl
RefSeq Acc Id: ENST00000548860
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,814,893 - 48,828,941 (+)Ensembl
RefSeq Acc Id: ENST00000548874   ⟹   ENSP00000446611
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,815,591 - 48,825,484 (+)Ensembl
RefSeq Acc Id: ENST00000549226
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,814,480 - 48,825,161 (+)Ensembl
RefSeq Acc Id: ENST00000549971
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,818,406 - 48,824,312 (+)Ensembl
RefSeq Acc Id: ENST00000550064   ⟹   ENSP00000448074
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,817,866 - 48,825,720 (+)Ensembl
RefSeq Acc Id: ENST00000550168
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,815,602 - 48,824,733 (+)Ensembl
RefSeq Acc Id: ENST00000550190   ⟹   ENSP00000447261
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,823,446 - 48,828,941 (+)Ensembl
RefSeq Acc Id: ENST00000550391   ⟹   ENSP00000449389
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,814,432 - 48,825,724 (+)Ensembl
RefSeq Acc Id: ENST00000550483   ⟹   ENSP00000448076
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,823,779 - 48,826,518 (+)Ensembl
RefSeq Acc Id: ENST00000550771
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,818,793 - 48,823,961 (+)Ensembl
RefSeq Acc Id: ENST00000551544   ⟹   ENSP00000447462
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,818,909 - 48,828,941 (+)Ensembl
RefSeq Acc Id: ENST00000551716
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,815,600 - 48,823,972 (+)Ensembl
RefSeq Acc Id: ENST00000552022
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,818,386 - 48,824,733 (+)Ensembl
RefSeq Acc Id: ENST00000552465
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,815,612 - 48,817,312 (+)Ensembl
RefSeq Acc Id: ENST00000552480
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,825,115 - 48,827,868 (+)Ensembl
RefSeq Acc Id: ENST00000552812
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1248,819,778 - 48,821,489 (+)Ensembl
RefSeq Acc Id: NM_000725   ⟹   NP_000716
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381248,818,496 - 48,828,941 (+)NCBI
GRCh371249,208,215 - 49,222,726 (+)ENTREZGENE
Build 361247,498,779 - 47,508,991 (+)NCBI Archive
HuRef1246,241,454 - 46,255,965 (+)ENTREZGENE
CHM1_11249,178,070 - 49,188,542 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001206915   ⟹   NP_001193844
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381248,818,496 - 48,828,941 (+)NCBI
GRCh371249,208,215 - 49,222,726 (+)ENTREZGENE
HuRef1246,241,454 - 46,255,965 (+)ENTREZGENE
CHM1_11249,178,070 - 49,188,542 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001206916   ⟹   NP_001193845
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381248,815,574 - 48,828,941 (+)NCBI
GRCh371249,208,215 - 49,222,726 (+)ENTREZGENE
HuRef1246,241,454 - 46,255,965 (+)ENTREZGENE
CHM1_11249,175,173 - 49,188,542 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001206917   ⟹   NP_001193846
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381248,814,480 - 48,828,941 (+)NCBI
GRCh371249,208,215 - 49,222,726 (+)ENTREZGENE
HuRef1246,241,454 - 46,255,965 (+)ENTREZGENE
CHM1_11249,174,031 - 49,188,542 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011538727   ⟹   XP_011537029
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381248,815,602 - 48,828,940 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011538728   ⟹   XP_011537030
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381248,819,072 - 48,828,940 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017019957   ⟹   XP_016875446
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381248,815,574 - 48,828,940 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024449180   ⟹   XP_024304948
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381248,815,804 - 48,828,751 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024449181   ⟹   XP_024304949
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381248,814,432 - 48,828,751 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001748867
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381248,818,766 - 48,828,941 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001748868
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381248,814,457 - 48,828,941 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001193846   ⟸   NM_001206917
- Peptide Label: isoform 4
- UniProtKB: P54284 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001193845   ⟸   NM_001206916
- Peptide Label: isoform 3
- UniProtKB: P54284 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_000716   ⟸   NM_000725
- Peptide Label: isoform 1
- UniProtKB: P54284 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001193844   ⟸   NM_001206915
- Peptide Label: isoform 2
- UniProtKB: P54284 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011537029   ⟸   XM_011538727
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011537030   ⟸   XM_011538728
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_016875446   ⟸   XM_017019957
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_024304949   ⟸   XM_024449181
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_024304948   ⟸   XM_024449180
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSP00000446529   ⟸   ENST00000547392
RefSeq Acc Id: ENSP00000448304   ⟸   ENST00000547230
RefSeq Acc Id: ENSP00000448137   ⟸   ENST00000547818
RefSeq Acc Id: ENSP00000446611   ⟸   ENST00000548874
RefSeq Acc Id: ENSP00000449497   ⟸   ENST00000548279
RefSeq Acc Id: ENSP00000444160   ⟸   ENST00000536187
RefSeq Acc Id: ENSP00000447261   ⟸   ENST00000550190
RefSeq Acc Id: ENSP00000448074   ⟸   ENST00000550064
RefSeq Acc Id: ENSP00000449389   ⟸   ENST00000550391
RefSeq Acc Id: ENSP00000448076   ⟸   ENST00000550483
RefSeq Acc Id: ENSP00000301050   ⟸   ENST00000301050
RefSeq Acc Id: ENSP00000447462   ⟸   ENST00000551544
RefSeq Acc Id: ENSP00000445495   ⟸   ENST00000540990
Protein Domains
GuKc   SH3

Promoters
RGD ID:6789767
Promoter ID:HG_KWN:15520
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:UC001RSK.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361247,494,226 - 47,495,577 (+)MPROMDB
RGD ID:6789766
Promoter ID:HG_KWN:15521
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   K562,   Lymphoblastoid
Transcripts:NM_000725
Position:
Human AssemblyChrPosition (strand)Source
Build 361247,498,154 - 47,498,654 (+)MPROMDB
RGD ID:7223757
Promoter ID:EPDNEW_H17624
Type:initiation region
Name:CACNB3_1
Description:calcium voltage-gated channel auxiliary subunit beta 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381248,818,796 - 48,818,856EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3 copy number gain See cases [RCV000139555] Chr12:121271..133196807 [GRCh38]
Chr12:282465..133773393 [GRCh37]
Chr12:100698..132283466 [NCBI36]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:1-133851895)x3 copy number gain See cases [RCV000258805] Chr12:1..133851895 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic|likely pathogenic
GRCh37/hg19 12p11.21-q13.12(chr12:31886971-50360461)x3 copy number gain See cases [RCV000207454] Chr12:31886971..50360461 [GRCh37]
Chr12:12p11.21-q13.12
pathogenic
GRCh37/hg19 12q13.11-13.12(chr12:48961450-49255821)x3 copy number gain See cases [RCV000448103] Chr12:48961450..49255821 [GRCh37]
Chr12:12q13.11-13.12
uncertain significance
GRCh37/hg19 12q11-13.12(chr12:37857750-49791459)x3 copy number gain See cases [RCV000448835] Chr12:37857750..49791459 [GRCh37]
Chr12:12q11-13.12
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902)x3 copy number gain See cases [RCV000510482] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902) copy number gain See cases [RCV000511643] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
NC_000012.11:g.26370251_54361538inv inversion not specified [RCV000714265] Chr12:26370251..54361538 [GRCh37]
Chr12:12p12.1-q13.13
uncertain significance
GRCh37/hg19 12q13.12(chr12:49191810-49630201)x3 copy number gain not provided [RCV000683434] Chr12:49191810..49630201 [GRCh37]
Chr12:12q13.12
uncertain significance
GRCh37/hg19 12p13.33-q24.33(chr12:191619-133777645)x3 copy number gain not provided [RCV000750246] Chr12:191619..133777645 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:621220-133779118)x3 copy number gain not provided [RCV000750253] Chr12:621220..133779118 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12q13.11-13.12(chr12:49055179-49466566)x3 copy number gain not provided [RCV000750395] Chr12:49055179..49466566 [GRCh37]
Chr12:12q13.11-13.12
benign
GRCh37/hg19 12q13.11-13.12(chr12:48944713-49265377)x3 copy number gain not provided [RCV000849162] Chr12:48944713..49265377 [GRCh37]
Chr12:12q13.11-13.12
uncertain significance
GRCh37/hg19 12q13.11-13.12(chr12:49034325-49468966)x1 copy number loss Kabuki syndrome 1 [RCV000859976] Chr12:49034325..49468966 [GRCh37]
Chr12:12q13.11-13.12
pathogenic
NM_000725.4(CACNB3):c.408-8C>A single nucleotide variant not provided [RCV000971393] Chr12:48824661 [GRCh38]
Chr12:49218444 [GRCh37]
Chr12:12q13.12
benign
GRCh37/hg19 12q13.11-13.12(chr12:49024019-50299974)x3 copy number gain not provided [RCV001259140] Chr12:49024019..50299974 [GRCh37]
Chr12:12q13.11-13.12
uncertain significance
GRCh37/hg19 12q11-13.12(chr12:37873948-49578619)x3 copy number gain See cases [RCV001353185] Chr12:37873948..49578619 [GRCh37]
Chr12:12q11-13.12
likely pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:1403 AgrOrtholog
COSMIC CACNB3 COSMIC
Ensembl Genes ENSG00000167535 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000301050 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000444160 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000445495 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000446529 UniProtKB/TrEMBL
  ENSP00000446611 UniProtKB/TrEMBL
  ENSP00000447261 UniProtKB/TrEMBL
  ENSP00000447462 UniProtKB/TrEMBL
  ENSP00000448074 UniProtKB/TrEMBL
  ENSP00000448076 UniProtKB/TrEMBL
  ENSP00000448137 UniProtKB/TrEMBL
  ENSP00000448304 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000449389 UniProtKB/TrEMBL
  ENSP00000449497 UniProtKB/TrEMBL
Ensembl Transcript ENST00000301050 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000536187 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000540990 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000547230 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000547392 UniProtKB/TrEMBL
  ENST00000547818 UniProtKB/TrEMBL
  ENST00000548279 UniProtKB/TrEMBL
  ENST00000548874 UniProtKB/TrEMBL
  ENST00000550064 UniProtKB/TrEMBL
  ENST00000550190 UniProtKB/TrEMBL
  ENST00000550391 UniProtKB/TrEMBL
  ENST00000550483 UniProtKB/TrEMBL
  ENST00000551544 ENTREZGENE, UniProtKB/TrEMBL
GTEx ENSG00000167535 GTEx
HGNC ID HGNC:1403 ENTREZGENE
Human Proteome Map CACNB3 Human Proteome Map
InterPro CACNB3_SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GK/Ca_channel_bsu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VDCC_L_b3su UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VDCC_L_bsu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:784 UniProtKB/Swiss-Prot
NCBI Gene 784 ENTREZGENE
OMIM 601958 OMIM
Pfam Guanylate_kin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VGCC_beta4Aa_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA89 PharmGKB
PRINTS LCACHANNELB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LCACHANNELB3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART GuKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CACB3_HUMAN UniProtKB/Swiss-Prot
  F8VNV8_HUMAN UniProtKB/TrEMBL
  F8VU10_HUMAN UniProtKB/TrEMBL
  F8VUW8_HUMAN UniProtKB/TrEMBL
  F8VV14_HUMAN UniProtKB/TrEMBL
  F8VWK1_HUMAN UniProtKB/TrEMBL
  F8W0F8_HUMAN UniProtKB/TrEMBL
  F8W1N3_HUMAN UniProtKB/TrEMBL
  H0YHK1_HUMAN UniProtKB/TrEMBL
  H0YHY2_HUMAN UniProtKB/TrEMBL
  P54284 ENTREZGENE
UniProt Secondary A8K0Z4 UniProtKB/Swiss-Prot
  B7Z4Q1 UniProtKB/Swiss-Prot
  B7Z973 UniProtKB/Swiss-Prot
  B7ZAK8 UniProtKB/Swiss-Prot
  F5GZW7 UniProtKB/Swiss-Prot
  F5H2P6 UniProtKB/Swiss-Prot
  F8VSG3 UniProtKB/Swiss-Prot
  Q13913 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-10 CACNB3  calcium voltage-gated channel auxiliary subunit beta 3    calcium channel, voltage-dependent, beta 3 subunit  Symbol and/or name change 5135510 APPROVED
2011-10-11 CACNB3  calcium channel, voltage-dependent, beta 3 subunit  CACNB3  calcium channel, voltage-dependent, beta 3 subunit  Symbol and/or name change 5135510 APPROVED