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Gene: GPER1 (G protein-coupled estrogen receptor 1) Homo sapiens
Symbol: GPER1
Name: G protein-coupled estrogen receptor 1
RGD ID: 735664
Description: Exhibits chromatin binding activity; estrogen receptor activity; and steroid hormone binding activity. Involved in several processes, including cellular response to hormone stimulus; positive regulation of cellular biosynthetic process; and regulation of signal transduction. Localizes to several cellular components, including cytoplasmic vesicle; keratin filament; and trans-Golgi network.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CEPR; chemoattractant receptor-like 2; chemokine receptor-like 2; CMKRL2; constitutively expressed peptide-like receptor; DRY12; FEG-1; flow-induced endothelial G-protein coupled receptor 1; G protein-coupled receptor 30; G-protein coupled estrogen receptor 1; G-protein coupled receptor 30; GPCR-Br; GPER; GPR30; heptahelix receptor; IL8-related receptor DRY12; LERGU; LERGU2; leucine rich protein in GPR30 3'UTR; LyGPR; lymphocyte-derived G-protein coupled receptor; membrane estrogen receptor; mER; MGC99678
Mus musculus (house mouse) : Gper1 (G protein-coupled estrogen receptor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gper1 (G protein-coupled estrogen receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gper1 (G protein-coupled estrogen receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100967334 (G-protein coupled estrogen receptor 1)
Canis lupus familiaris (dog) : GPER1 (G protein-coupled estrogen receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gper1 (G protein-coupled estrogen receptor 1)
Sus scrofa (pig) : GPER1 (G protein-coupled estrogen receptor 1)
Chlorocebus sabaeus (African green monkey) : GPER1 (G protein-coupled estrogen receptor 1)
Heterocephalus glaber (naked mole-rat) : Gper1 (G protein-coupled estrogen receptor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl71,082,208 - 1,093,815 (+)EnsemblGRCh38hg38GRCh38
GRCh3871,087,118 - 1,093,810 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3771,126,443 - 1,133,451 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3671,092,969 - 1,099,977 (+)NCBINCBI36hg18NCBI36
Build 347899,752 - 906,692NCBI
Celera71,094,088 - 1,101,068 (+)NCBI
Cytogenetic Map7p22.3NCBI
HuRef71,041,713 - 1,048,693 (+)NCBIHuRef
CHM1_171,126,080 - 1,133,090 (+)NCBICHM1_1
CRA_TCAGchr7v271,180,870 - 1,187,850 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on GPER1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735664
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.