GPER1 Human (S)-amphetamine increases expression ISO Gper1 (Rattus norvegicus) 6480464 Dextroamphetamine results in increased expression of GPER1 mRNA CTD PMID:16715494 GPER1 Human (S)-naringenin multiple interactions EXP 6480464 [Tamoxifen co-treated with naringenin] results in decreased expression of GPER1 mRNA and [Tamoxifen co-treated with naringenin] results in decreased expression of GPER1 protein CTD PMID:30153467 GPER1 Human (S)-naringenin decreases expression EXP 6480464 naringenin metabolite results in decreased expression of GPER1 mRNA more ... CTD PMID:30153467 and PMID:36235125 GPER1 Human 1,2-dimethylhydrazine decreases expression ISO Gper1 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of GPER1 mRNA CTD PMID:22206623 GPER1 Human 1,3,5-trinitro-1,3,5-triazinane increases expression ISO Gper1 (Rattus norvegicus) 6480464 cyclonite results in increased expression of GPER1 mRNA CTD PMID:25559034 GPER1 Human 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of GPER1 mRNA CTD PMID:29783106 GPER1 Human 17beta-estradiol multiple interactions EXP 6480464 2 more ... CTD PMID:15090535 more ... GPER1 Human 17beta-estradiol increases expression ISO Gper1 (Mus musculus) 6480464 Estradiol results in increased expression of GPER1 protein CTD PMID:29360751 GPER1 Human 17beta-estradiol increases expression ISO Gper1 (Rattus norvegicus) 6480464 Estradiol results in increased expression of GPER1 mRNA CTD PMID:27174447 GPER1 Human 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of GPER1 mRNA and Estradiol results in increased expression of GPER1 protein CTD PMID:17121429 more ... GPER1 Human 17beta-estradiol affects binding EXP 6480464 Estradiol analog binds to GPER1 protein and Estradiol binds to GPER1 protein CTD PMID:25616260 more ... GPER1 Human 17beta-estradiol affects response to substance EXP 6480464 GPER1 protein affects the susceptibility to Estradiol CTD PMID:24440569 GPER1 Human 17beta-estradiol affects response to substance ISO Gper1 (Rattus norvegicus) 6480464 GPER1 protein affects the susceptibility to Estradiol CTD PMID:22265196 GPER1 Human 17beta-estradiol multiple interactions ISO Gper1 (Rattus norvegicus) 6480464 [Estradiol co-treated with bisphenol A] results in decreased expression of GPER mRNA and GPER1 protein affects the reaction [Estradiol results in decreased expression of HTR1A protein] CTD PMID:22265196 and PMID:35700937 GPER1 Human 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of GPER1 mRNA CTD PMID:21185374 more ... GPER1 Human 17beta-estradiol multiple interactions ISO Gper1 (Mus musculus) 6480464 Estradiol affects the reaction [PTK2B protein affects the expression of GPER1 mRNA] and GPER1 affects the reaction [Estradiol results in increased expression of FOS mRNA] CTD PMID:21813366 and PMID:29428397 GPER1 Human 17beta-estradiol increases activity EXP 6480464 Estradiol results in increased activity of GPER1 protein CTD PMID:19153601 GPER1 Human 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Gper1 (Mus musculus) 6480464 [Dietary Sucrose co-treated with Dietary Fats co-treated with bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:30722647 and PMID:32784060 GPER1 Human 2,2',4,4'-Tetrabromodiphenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:23146750 GPER1 Human 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions EXP 6480464 2 more ... CTD PMID:29790728 GPER1 Human 2,2',4,5'-Tetrabromodiphenyl ether multiple interactions EXP 6480464 2 more ... CTD PMID:29790728 GPER1 Human 2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene affects binding EXP 6480464 2 more ... CTD PMID:17088055 GPER1 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of GPER1 mRNA CTD PMID:20106945 more ... GPER1 Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Gper1 (Mus musculus) 6480464 [Dietary Sucrose co-treated with Dietary Fats co-treated with bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:30722647 and PMID:32784060 GPER1 Human 2,3-dimethoxynaphthalene-1,4-dione decreases expression EXP 6480464 2 more ... CTD PMID:17547211 GPER1 Human 2,4-dibromophenyl 2,4,5-tribromophenyl ether multiple interactions EXP 6480464 2 more ... CTD PMID:29790728 GPER1 Human 3,3',5,5'-tetrabromobisphenol A decreases expression ISO Gper1 (Mus musculus) 6480464 tetrabromobisphenol A results in decreased expression of GPER1 mRNA CTD PMID:25172293 GPER1 Human 3,3',5,5'-tetrabromobisphenol A increases expression ISO Gper1 (Mus musculus) 6480464 tetrabromobisphenol A results in increased expression of GPER1 mRNA CTD PMID:30496566 GPER1 Human 4,4'-sulfonyldiphenol affects binding EXP 6480464 bisphenol S binds to GPER1 protein CTD PMID:28858478 GPER1 Human 4,4'-sulfonyldiphenol decreases expression EXP 6480464 bisphenol S results in decreased expression of GPER1 protein CTD PMID:34831106 GPER1 Human 4,4'-sulfonyldiphenol decreases methylation ISO Gper1 (Mus musculus) 6480464 bisphenol S results in decreased methylation of GPER1 exon CTD PMID:33297965 GPER1 Human 4,4'-sulfonyldiphenol decreases expression ISO Gper1 (Mus musculus) 6480464 bisphenol S results in decreased expression of GPER1 mRNA CTD PMID:35569583 GPER1 Human 4,4'-thiodiphenol increases expression EXP 6480464 bis(4-oxyphenyl)sulfide results in increased expression of GPER1 protein CTD PMID:27880919 GPER1 Human 4,4'-thiodiphenol multiple interactions EXP 6480464 4-(6-bromo-1 more ... CTD PMID:27880919 GPER1 Human 4-nonylphenol increases expression EXP 6480464 4-nonylphenol results in increased expression of GPER1 mRNA CTD PMID:29783106 GPER1 Human 4-tert-Octylphenol increases expression EXP 6480464 4-tert-octylphenol results in increased expression of GPER1 mRNA CTD PMID:29783106 GPER1 Human 5-aza-2'-deoxycytidine affects expression EXP 6480464 Decitabine affects the expression of GPER1 mRNA CTD PMID:23300844 GPER1 Human 5-aza-2'-deoxycytidine decreases methylation EXP 6480464 Decitabine results in decreased methylation of GPER1 promoter CTD PMID:23300844 GPER1 Human 6-propyl-2-thiouracil increases expression ISO Gper1 (Rattus norvegicus) 6480464 Propylthiouracil results in increased expression of GPER1 mRNA CTD PMID:22504374 GPER1 Human afimoxifene multiple interactions EXP 6480464 GPER1 protein affects the reaction [afimoxifene results in increased cleavage of CCNE1 protein] more ... CTD PMID:19153601 and PMID:23624423 GPER1 Human afimoxifene affects response to substance EXP 6480464 GPER1 protein affects the susceptibility to afimoxifene CTD PMID:19153601 GPER1 Human afimoxifene increases activity EXP 6480464 afimoxifene results in increased activity of GPER1 protein CTD PMID:19153601 GPER1 Human aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of GPER1 mRNA CTD PMID:27153756 GPER1 Human all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of GPER1 mRNA CTD PMID:23724009 GPER1 Human all-trans-retinoic acid multiple interactions ISO Gper1 (Mus musculus) 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GPER1 mRNA CTD PMID:36189433 GPER1 Human ammonium chloride affects expression ISO Gper1 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of GPER1 mRNA CTD PMID:16483693 GPER1 Human antirheumatic drug increases expression EXP 6480464 Antirheumatic Agents results in increased expression of GPER1 mRNA CTD PMID:24449571 GPER1 Human aristolochic acid A increases expression EXP 6480464 aristolochic acid I results in increased expression of GPER1 mRNA CTD PMID:33212167 GPER1 Human arsenite(3-) increases expression EXP 6480464 arsenite results in increased expression of GPER1 mRNA CTD PMID:31646340 GPER1 Human arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of GPER1 mRNA CTD PMID:17547211 and PMID:19128835 GPER1 Human atrazine multiple interactions EXP 6480464 Atrazine binds to and results in increased activity of GPER1 protein more ... CTD PMID:25616260 GPER1 Human atrazine affects expression EXP 6480464 Atrazine affects the expression of GPER1 mRNA CTD PMID:26955487 GPER1 Human atrazine decreases expression ISO Gper1 (Rattus norvegicus) 6480464 Atrazine results in decreased expression of GPER1 mRNA CTD PMID:36841081 GPER1 Human benzo[a]pyrene increases methylation EXP 6480464 Benzo(a)pyrene results in increased methylation of GPER exon CTD PMID:27901495 GPER1 Human benzo[a]pyrene affects methylation EXP 6480464 Benzo(a)pyrene affects the methylation of GPER 5' UTR and Benzo(a)pyrene affects the methylation of GPER promoter CTD PMID:27901495 GPER1 Human Benzo[ghi]perylene increases expression ISO Gper1 (Mus musculus) 6480464 1 and 12-benzoperylene results in increased expression of GPER1 mRNA CTD PMID:26377693 GPER1 Human bis(2-ethylhexyl) phthalate decreases expression ISO Gper1 (Rattus norvegicus) 6480464 Diethylhexyl Phthalate results in decreased expression of GPER1 mRNA CTD PMID:15620428 GPER1 Human bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of GPER1 mRNA CTD PMID:33846374 GPER1 Human bis(2-ethylhexyl) phthalate increases expression ISO Gper1 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of GPER1 mRNA CTD PMID:34600010 GPER1 Human bis(2-ethylhexyl) phthalate multiple interactions ISO Gper1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of GPER1 protein more ... CTD PMID:30722647 more ... GPER1 Human bisphenol A multiple interactions EXP 6480464 [Estradiol co-treated with bisphenol A] results in increased expression of GPER1 mRNA more ... CTD PMID:17088055 more ... GPER1 Human bisphenol A multiple interactions ISO Gper1 (Rattus norvegicus) 6480464 [Estradiol co-treated with bisphenol A] results in decreased expression of GPER mRNA CTD PMID:35700937 GPER1 Human bisphenol A decreases expression ISO Gper1 (Mus musculus) 6480464 bisphenol A results in decreased expression of GPER1 mRNA and bisphenol A results in decreased expression of GPER1 protein CTD PMID:30149043 more ... GPER1 Human bisphenol A decreases methylation ISO Gper1 (Mus musculus) 6480464 bisphenol A results in decreased methylation of GPER1 promoter CTD PMID:27312807 GPER1 Human bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of GPER mRNA more ... CTD PMID:28426875 more ... GPER1 Human bisphenol A affects binding EXP 6480464 bisphenol A binds to GPER1 protein CTD PMID:28858478 and PMID:34328988 GPER1 Human bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of GPER1 mRNA and bisphenol A results in decreased expression of GPER1 protein CTD PMID:25878060 more ... GPER1 Human bisphenol A increases activity ISO Gper1 (Mus musculus) 6480464 bisphenol A results in increased activity of GPER1 protein CTD PMID:24604882 GPER1 Human bisphenol A increases expression ISO Gper1 (Mus musculus) 6480464 bisphenol A results in increased expression of GPER1 mRNA and bisphenol A results in increased expression of GPER1 protein CTD PMID:22707478 more ... GPER1 Human bisphenol A increases expression ISO Gper1 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of GPER1 mRNA CTD PMID:24189132 GPER1 Human bisphenol A decreases expression ISO Gper1 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of GPER1 mRNA CTD PMID:25181051 and PMID:30755151 GPER1 Human bisphenol A multiple interactions ISO Gper1 (Mus musculus) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A promotes the reaction [FOS protein binds to GPER1 promoter]] more ... CTD PMID:21813366 more ... GPER1 Human bisphenol AF multiple interactions EXP 6480464 GPER1 protein affects the reaction [bisphenol AF results in increased phosphorylation of AKT1 protein] CTD PMID:30590302 GPER1 Human bisphenol AF affects binding EXP 6480464 bisphenol AF binds to GPER1 protein CTD PMID:28858478 and PMID:34328988 GPER1 Human bisphenol AF increases expression ISO Gper1 (Mus musculus) 6480464 bisphenol AF results in increased expression of GPER1 mRNA and bisphenol AF results in increased expression of GPER1 protein CTD PMID:31981723 GPER1 Human bisphenol AF increases expression EXP 6480464 bisphenol AF results in increased expression of GPER1 mRNA and bisphenol AF results in increased expression of GPER1 protein CTD PMID:30590302 and PMID:36190352 GPER1 Human bisphenol AF multiple interactions ISO Gper1 (Mus musculus) 6480464 4-(6-bromo-1 more ... CTD PMID:31981723 GPER1 Human Bisphenol B affects binding EXP 6480464 bisphenol B binds to GPER1 protein CTD PMID:28858478 and PMID:34328988 GPER1 Human Bisphenol B decreases expression EXP 6480464 bisphenol B results in decreased expression of GPER1 mRNA CTD PMID:32387340 GPER1 Human bisphenol F increases expression EXP 6480464 4 and 4'-bisphenol F results in increased expression of GPER1 protein CTD PMID:30195206 GPER1 Human bisphenol F decreases expression EXP 6480464 bisphenol F results in decreased expression of GPER1 protein CTD PMID:34831106 GPER1 Human bisphenol F increases expression ISO Gper1 (Rattus norvegicus) 6480464 bisphenol F results in increased expression of GPER1 mRNA and bisphenol F results in increased expression of GPER1 protein CTD PMID:35803362 GPER1 Human bisphenol F affects binding EXP 6480464 bisphenol F binds to GPER1 protein CTD PMID:34328988 GPER1 Human bisphenol F multiple interactions EXP 6480464 4-(6-bromo-1 more ... CTD PMID:30195206 GPER1 Human Bisphenol Z decreases expression EXP 6480464 bisphenol Z results in decreased expression of GPER1 mRNA CTD PMID:32387340 GPER1 Human Butylbenzyl phthalate multiple interactions ISO Gper1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of GPER1 protein and [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of GPER1 mRNA CTD PMID:35739755 and PMID:37364641 GPER1 Human Butylparaben increases expression EXP 6480464 butylparaben results in increased expression of GPER1 mRNA and butylparaben results in increased expression of GPER1 protein CTD PMID:17121429 and PMID:26253279 GPER1 Human cadmium atom decreases expression EXP 6480464 Cadmium results in decreased expression of GPER1 mRNA CTD PMID:17547211 and PMID:31646340 GPER1 Human cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GPER1 mRNA more ... CTD PMID:20153348 more ... GPER1 Human cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of GPER1 mRNA CTD PMID:17547211 and PMID:38568856 GPER1 Human cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of GPER1 mRNA CTD PMID:38382870 GPER1 Human cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GPER1 mRNA more ... CTD PMID:31468104 GPER1 Human chlordecone multiple interactions EXP 6480464 Chlordecone binds to and results in increased activity of GPER1 protein CTD PMID:17088055 GPER1 Human chlorpyrifos increases expression ISO Gper1 (Mus musculus) 6480464 Chlorpyrifos results in increased expression of GPER1 mRNA CTD PMID:37019170 GPER1 Human chromium atom decreases expression EXP 6480464 Chromium results in decreased expression of GPER1 mRNA CTD PMID:17547211 GPER1 Human cisplatin affects expression EXP 6480464 Cisplatin affects the expression of GPER1 mRNA CTD PMID:23300844 GPER1 Human clobetasol increases expression ISO Gper1 (Mus musculus) 6480464 Clobetasol results in increased expression of GPER1 mRNA CTD PMID:27462272 GPER1 Human cocaine increases expression ISO Gper1 (Rattus norvegicus) 6480464 Cocaine results in increased expression of GPER1 mRNA CTD PMID:17898221 GPER1 Human copper(II) sulfate decreases expression EXP 6480464 Copper Sulfate results in decreased expression of GPER1 mRNA CTD PMID:19549813 GPER1 Human coumestrol multiple interactions EXP 6480464 [Coumestrol co-treated with resveratrol] results in decreased expression of GPER1 mRNA CTD PMID:19167446 GPER1 Human cumene multiple interactions ISO Gper1 (Mus musculus) 6480464 [cumene co-treated with KRAS gene mutant form] results in decreased expression of GPER1 mRNA CTD PMID:18648096 GPER1 Human curcumin decreases expression EXP 6480464 Curcumin results in decreased expression of GPER1 mRNA CTD PMID:17198877 GPER1 Human cyanazine affects expression EXP 6480464 cyanazine affects the expression of GPER1 mRNA CTD PMID:26955487 GPER1 Human cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of GPER1 mRNA CTD PMID:20106945 and PMID:25562108 GPER1 Human cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of GPER1 mRNA CTD PMID:27989131 GPER1 Human cytarabine decreases expression EXP 6480464 Cytarabine results in decreased expression of GPER1 mRNA CTD PMID:21198554 GPER1 Human daidzein multiple interactions EXP 6480464 daidzein inhibits the reaction [bisphenol A results in decreased expression of GPER1 mRNA] CTD PMID:32963737 GPER1 Human DDT affects binding EXP 6480464 DDT binds to GPER1 protein CTD PMID:17088055 GPER1 Human DDT increases methylation ISO Gper1 (Mus musculus) 6480464 DDT results in increased methylation of GPER1 gene CTD PMID:28263910 GPER1 Human DDT affects expression ISO Gper1 (Mus musculus) 6480464 DDT affects the expression of GPER1 mRNA CTD PMID:28263910 GPER1 Human DDT decreases expression ISO Gper1 (Mus musculus) 6480464 DDT results in decreased expression of GPER1 protein CTD PMID:28263910 GPER1 Human dehydroepiandrosterone multiple interactions EXP 6480464 4-(6-bromo-1 more ... CTD PMID:25969534 GPER1 Human dehydroepiandrosterone increases expression EXP 6480464 Dehydroepiandrosterone results in increased expression of GPER1 mRNA and Dehydroepiandrosterone results in increased expression of GPER1 protein CTD PMID:25969534 GPER1 Human dexamethasone decreases expression ISO Gper1 (Mus musculus) 6480464 Dexamethasone results in decreased expression of GPER1 mRNA CTD PMID:22733784 GPER1 Human Di-n-octyl phthalate multiple interactions ISO Gper1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of GPER1 protein and [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of GPER1 mRNA CTD PMID:35739755 and PMID:37364641 GPER1 Human diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of GPER1 mRNA CTD PMID:17547211 and PMID:19128835 GPER1 Human dibutyl phthalate decreases expression ISO Gper1 (Rattus norvegicus) 6480464 Dibutyl Phthalate results in decreased expression of GPER1 mRNA CTD PMID:15620428 GPER1 Human dibutyl phthalate multiple interactions ISO Gper1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of GPER1 protein and [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of GPER1 mRNA CTD PMID:35739755 and PMID:37364641 GPER1 Human diethyl phthalate multiple interactions ISO Gper1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of GPER1 protein and [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of GPER1 mRNA CTD PMID:35739755 and PMID:37364641 GPER1 Human diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of GPER1 mRNA CTD PMID:29783106 GPER1 Human Diisodecyl phthalate multiple interactions ISO Gper1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of GPER1 protein and [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of GPER1 mRNA CTD PMID:35739755 and PMID:37364641 GPER1 Human diisononyl phthalate multiple interactions ISO Gper1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of GPER1 protein and [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of GPER1 mRNA CTD PMID:35739755 and PMID:37364641 GPER1 Human dioxygen increases expression ISO Gper1 (Mus musculus) 6480464 Oxygen deficiency results in increased expression of GPER1 mRNA CTD PMID:24846829 GPER1 Human dioxygen multiple interactions ISO Gper1 (Mus musculus) 6480464 Raloxifene Hydrochloride inhibits the reaction [Oxygen deficiency results in increased expression of GPER1 mRNA] CTD PMID:24846829 GPER1 Human disodium selenite increases expression ISO Gper1 (Mus musculus) 6480464 Sodium Selenite results in increased expression of GPER1 protein CTD PMID:37142062 GPER1 Human endosulfan decreases expression ISO Gper1 (Rattus norvegicus) 6480464 Endosulfan results in decreased expression of GPER1 mRNA CTD PMID:29391264 GPER1 Human folic acid decreases expression ISO Gper1 (Mus musculus) 6480464 Folic Acid results in decreased expression of GPER1 mRNA CTD PMID:25629700 GPER1 Human FR900359 multiple interactions EXP 6480464 FR900359 inhibits the reaction [[GPER1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK1 protein] and FR900359 inhibits the reaction [[GPER1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK3 protein] CTD PMID:37372083 GPER1 Human fulvestrant multiple interactions EXP 6480464 4-(6-bromo-1 more ... CTD PMID:20211987 more ... GPER1 Human fulvestrant multiple interactions ISO Gper1 (Mus musculus) 6480464 Fulvestrant inhibits the reaction [bisphenol A results in increased expression of GPER1 mRNA] more ... CTD PMID:28446726 and PMID:37084542 GPER1 Human fulvestrant increases expression EXP 6480464 Fulvestrant results in increased expression of GPER1 mRNA and Fulvestrant results in increased expression of GPER1 protein CTD PMID:25969534 more ... GPER1 Human fulvestrant decreases response to substance EXP 6480464 GPER1 mutant form results in decreased susceptibility to fulvestrant CTD PMID:24169358 GPER1 Human fulvestrant affects response to substance EXP 6480464 GPER1 protein affects the susceptibility to fulvestrant CTD PMID:24440569 GPER1 Human gefitinib multiple interactions EXP 6480464 Gefitinib inhibits the reaction [tetrachlorodian results in increased expression of GPER1 mRNA] CTD PMID:36190352 GPER1 Human genistein multiple interactions EXP 6480464 Genistein binds to and results in increased activity of GPER1 protein more ... CTD PMID:15090535 more ... GPER1 Human glyphosate increases expression ISO Gper1 (Rattus norvegicus) 6480464 Glyphosate results in increased expression of GPER1 mRNA and Glyphosate results in increased expression of GPER1 protein CTD PMID:24930125 GPER1 Human herbicide increases expression ISO Gper1 (Rattus norvegicus) 6480464 Herbicides results in increased expression of GPER1 mRNA and Herbicides results in increased expression of GPER1 protein CTD PMID:24930125 GPER1 Human hexachlorobenzene increases expression ISO Gper1 (Mus musculus) 6480464 Hexachlorobenzene results in increased expression of GPER1 protein CTD PMID:37169060 GPER1 Human hydroquinone O-beta-D-glucopyranoside increases expression ISO Gper1 (Mus musculus) 6480464 Arbutin results in increased expression of GPER1 protein CTD PMID:29360751 GPER1 Human hydroquinone O-beta-D-glucopyranoside increases expression EXP 6480464 Arbutin results in increased expression of GPER1 protein CTD PMID:29360751 GPER1 Human iron dichloride decreases expression EXP 6480464 ferrous chloride results in decreased expression of GPER1 mRNA CTD PMID:35984750 GPER1 Human KT 5720 multiple interactions ISO Gper1 (Rattus norvegicus) 6480464 KT 5720 inhibits the reaction [[1-(4-(6-bromobenzo(1 more ... CTD PMID:22645130 GPER1 Human KT 5823 multiple interactions ISO Gper1 (Mus musculus) 6480464 KT 5823 inhibits the reaction [bisphenol A promotes the reaction [FOS protein binds to GPER1 promoter]] more ... CTD PMID:23274518 GPER1 Human LY294002 multiple interactions ISO Gper1 (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[1-(4-(6-bromobenzo(1 more ... CTD PMID:22645130 and PMID:33035625 GPER1 Human manganese atom multiple interactions ISO Gper1 (Rattus norvegicus) 6480464 [1-(4-(6-bromobenzo(1 more ... CTD PMID:22645130 GPER1 Human manganese(0) multiple interactions ISO Gper1 (Rattus norvegicus) 6480464 [1-(4-(6-bromobenzo(1 more ... CTD PMID:22645130 GPER1 Human mercury atom decreases expression EXP 6480464 Mercury results in decreased expression of GPER1 mRNA CTD PMID:17547211 GPER1 Human mercury(0) decreases expression EXP 6480464 Mercury results in decreased expression of GPER1 mRNA CTD PMID:17547211 GPER1 Human mestranol increases expression ISO Gper1 (Mus musculus) 6480464 Mestranol results in increased expression of GPER1 protein CTD PMID:36098747 GPER1 Human methimazole increases expression ISO Gper1 (Rattus norvegicus) 6480464 Methimazole results in increased expression of GPER1 mRNA CTD PMID:22504374 GPER1 Human methylparaben increases expression EXP 6480464 methylparaben results in increased expression of GPER1 mRNA and methylparaben results in increased expression of GPER1 protein CTD PMID:17121429 and PMID:26253279 GPER1 Human mono(2-ethylhexyl) phthalate multiple interactions ISO Gper1 (Mus musculus) 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GPER1 mRNA CTD PMID:36189433 GPER1 Human N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO Gper1 (Rattus norvegicus) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[1-(4-(6-bromobenzo(1 more ... CTD PMID:22645130 GPER1 Human N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions EXP 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[GPER1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK1 protein] and N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[GPER1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK3 protein] CTD PMID:37372083 GPER1 Human N-methyl-4-phenylpyridinium multiple interactions ISO Gper1 (Rattus norvegicus) 6480464 GPER1 protein promotes the reaction [IGF1 inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NOS2 mRNA]] more ... CTD PMID:33035625 GPER1 Human N-nitrosodimethylamine decreases expression EXP 6480464 Dimethylnitrosamine results in decreased expression of GPER1 mRNA CTD PMID:17547211 GPER1 Human nickel atom decreases expression EXP 6480464 Nickel results in decreased expression of GPER1 mRNA CTD PMID:25583101 GPER1 Human nickel dichloride decreases expression EXP 6480464 nickel chloride results in decreased expression of GPER1 mRNA CTD PMID:17547211 GPER1 Human nickel sulfate increases expression EXP 6480464 nickel sulfate results in increased expression of GPER1 mRNA CTD PMID:22714537 GPER1 Human Nonylphenol increases activity ISO Gper1 (Mus musculus) 6480464 nonylphenol results in increased activity of GPER1 protein CTD PMID:24604882 GPER1 Human Nonylphenol multiple interactions EXP 6480464 nonylphenol binds to and results in increased activity of GPER1 protein CTD PMID:17088055 GPER1 Human Nonylphenol decreases expression ISO Gper1 (Rattus norvegicus) 6480464 nonylphenol results in decreased expression of GPER1 mRNA CTD PMID:15620428 GPER1 Human oxybenzone affects expression ISO Gper1 (Rattus norvegicus) 6480464 oxybenzone affects the expression of GPER1 protein CTD PMID:30099065 GPER1 Human p-tert-Amylphenol increases expression EXP 6480464 4-tert-octylphenol results in increased expression of GPER1 mRNA CTD PMID:29783106 GPER1 Human paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of GPER1 mRNA CTD PMID:21420995 GPER1 Human paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of GPER1 mRNA CTD PMID:26690555 and PMID:29067470 GPER1 Human paraquat increases expression ISO Gper1 (Rattus norvegicus) 6480464 Paraquat results in increased expression of GPER1 mRNA CTD PMID:17077588 GPER1 Human perfluorohexanesulfonic acid increases expression ISO Gper1 (Mus musculus) 6480464 perfluorohexanesulfonic acid results in increased expression of GPER1 mRNA CTD PMID:37995155 GPER1 Human perfluorononanoic acid decreases expression EXP 6480464 perfluoro-n-nonanoic acid results in decreased expression of GPER1 mRNA CTD PMID:32588087 GPER1 Human phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of GPER1 mRNA CTD PMID:19159669 GPER1 Human potassium dichromate decreases expression EXP 6480464 Potassium Dichromate results in decreased expression of GPER1 mRNA CTD PMID:17547211 GPER1 Human propylparaben increases expression EXP 6480464 propylparaben results in increased expression of GPER1 mRNA and propylparaben results in increased expression of GPER1 protein CTD PMID:26253279 GPER1 Human puerarin multiple interactions EXP 6480464 Sirolimus inhibits the reaction [puerarin results in increased expression of GPER1 protein] CTD PMID:27796870 GPER1 Human puerarin increases expression EXP 6480464 puerarin results in increased expression of GPER1 protein CTD PMID:27796870 GPER1 Human pyrrolidine dithiocarbamate multiple interactions ISO Gper1 (Rattus norvegicus) 6480464 pyrrolidine dithiocarbamic acid inhibits the reaction [[1-(4-(6-bromobenzo(1 more ... CTD PMID:22645130 GPER1 Human quercetin multiple interactions EXP 6480464 GPER1 protein affects the reaction [Quercetin results in increased expression of FOS protein] and Tamoxifen inhibits the reaction [Quercetin results in increased expression of GPER1 mRNA] CTD PMID:15090535 and PMID:32530119 GPER1 Human quercetin increases expression EXP 6480464 Quercetin results in increased expression of GPER1 mRNA CTD PMID:32530119 and PMID:36982678 GPER1 Human quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of GPER1 mRNA CTD PMID:15309432 GPER1 Human quinazolines multiple interactions ISO Gper1 (Rattus norvegicus) 6480464 Quinazolines inhibits the reaction [[1-(4-(6-bromobenzo(1 more ... CTD PMID:22645130 GPER1 Human raloxifene increases activity ISO Gper1 (Rattus norvegicus) 6480464 Raloxifene Hydrochloride results in increased activity of GPER1 protein CTD PMID:24782323 GPER1 Human raloxifene multiple interactions ISO Gper1 (Mus musculus) 6480464 Raloxifene Hydrochloride inhibits the reaction [Oxygen deficiency results in increased expression of GPER1 mRNA] CTD PMID:24846829 GPER1 Human raloxifene multiple interactions EXP 6480464 GPER1 protein affects the reaction [Raloxifene Hydrochloride affects the localization of FOXO3 protein] more ... CTD PMID:22453024 more ... GPER1 Human raloxifene multiple interactions ISO Gper1 (Rattus norvegicus) 6480464 [4-(6-bromo-1 more ... CTD PMID:24782323 GPER1 Human resveratrol multiple interactions EXP 6480464 [Coumestrol co-treated with resveratrol] results in decreased expression of GPER1 mRNA CTD PMID:19167446 GPER1 Human S-(1,2-dichlorovinyl)-L-cysteine decreases expression EXP 6480464 S-(1 and 2-dichlorovinyl)cysteine results in decreased expression of GPER1 mRNA CTD PMID:33725128 GPER1 Human silicon dioxide decreases expression EXP 6480464 Silicon Dioxide analog results in decreased expression of GPER1 mRNA CTD PMID:25895662 GPER1 Human silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of GPER1 mRNA CTD PMID:34973136 GPER1 Human simazine affects expression EXP 6480464 Simazine affects the expression of GPER1 mRNA CTD PMID:26955487 GPER1 Human sirolimus multiple interactions EXP 6480464 Sirolimus inhibits the reaction [puerarin results in increased expression of GPER1 protein] CTD PMID:27796870 GPER1 Human sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of GPER1 mRNA CTD PMID:22714537 GPER1 Human sodium arsenite increases expression ISO Gper1 (Mus musculus) 6480464 sodium arsenite results in increased expression of GPER1 mRNA CTD PMID:37682722 GPER1 Human sodium arsenite affects expression EXP 6480464 sodium arsenite affects the expression of GPER1 mRNA CTD PMID:34032870 GPER1 Human sulforaphane decreases expression EXP 6480464 sulforaphane results in decreased expression of GPER1 mRNA CTD PMID:31838189 GPER1 Human sunitinib decreases expression EXP 6480464 Sunitinib results in decreased expression of GPER1 mRNA CTD PMID:31533062 GPER1 Human tamoxifen multiple interactions EXP 6480464 [Tamoxifen co-treated with naringenin] results in decreased expression of GPER1 mRNA more ... CTD PMID:20211987 more ... GPER1 Human tamoxifen decreases expression EXP 6480464 Tamoxifen results in decreased expression of GPER1 mRNA and Tamoxifen results in decreased expression of GPER1 protein CTD PMID:30153467 and PMID:32530119 GPER1 Human tamoxifen decreases response to substance EXP 6480464 GPER1 protein results in decreased susceptibility to Tamoxifen CTD PMID:19911269 GPER1 Human tamoxifen increases activity EXP 6480464 Tamoxifen analog results in increased activity of GPER1 protein CTD PMID:19549922 GPER1 Human temozolomide increases expression EXP 6480464 Temozolomide results in increased expression of GPER1 mRNA CTD PMID:31758290 GPER1 Human tert-butyl hydroperoxide decreases expression EXP 6480464 tert-Butylhydroperoxide results in decreased expression of GPER1 mRNA CTD PMID:15336504 GPER1 Human testosterone decreases expression ISO Gper1 (Mus musculus) 6480464 Testosterone deficiency results in decreased expression of GPER1 mRNA CTD PMID:33848595 GPER1 Human Tetrachlorobisphenol A affects binding EXP 6480464 tetrachlorodian binds to GPER1 protein CTD PMID:28858478 GPER1 Human Tetrachlorobisphenol A increases expression EXP 6480464 tetrachlorodian results in increased expression of GPER1 mRNA and tetrachlorodian results in increased expression of GPER1 protein CTD PMID:33582643 and PMID:36190352 GPER1 Human Tetrachlorobisphenol A multiple interactions EXP 6480464 4-(6-bromo-1 more ... CTD PMID:36190352 GPER1 Human Tetrachlorobisphenol A multiple interactions ISO Gper1 (Mus musculus) 6480464 4-(6-bromo-1 more ... CTD PMID:37992829 GPER1 Human Tetrachlorobisphenol A increases expression ISO Gper1 (Mus musculus) 6480464 tetrachlorodian results in increased expression of GPER1 mRNA and tetrachlorodian results in increased expression of GPER1 protein CTD PMID:37992829 GPER1 Human Tetrachlorobisphenol A affects expression ISO Gper1 (Rattus norvegicus) 6480464 tetrachlorodian affects the expression of GPER1 mRNA CTD PMID:37992829 GPER1 Human thiram decreases expression EXP 6480464 Thiram results in decreased expression of GPER1 mRNA CTD PMID:38568856 GPER1 Human toluene increases expression ISO Gper1 (Rattus norvegicus) 6480464 Toluene results in increased expression of GPER1 mRNA CTD PMID:22967744 GPER1 Human triclocarban increases expression ISO Gper1 (Rattus norvegicus) 6480464 triclocarban results in increased expression of GPER1 mRNA CTD PMID:31576746 GPER1 Human tyrphostin AG 1478 multiple interactions EXP 6480464 RTKI cpd inhibits the reaction [EGF protein results in increased expression of GPER1 protein] more ... CTD PMID:19749156 GPER1 Human tyrphostin AG 1478 multiple interactions ISO Gper1 (Rattus norvegicus) 6480464 RTKI cpd inhibits the reaction [[1-(4-(6-bromobenzo(1 more ... CTD PMID:22645130 GPER1 Human tyrphostin AG 1478 multiple interactions ISO Gper1 (Mus musculus) 6480464 RTKI cpd inhibits the reaction [bisphenol A promotes the reaction [FOS protein binds to GPER1 promoter]] more ... CTD PMID:23274518 GPER1 Human urethane decreases expression EXP 6480464 Urethane results in decreased expression of GPER1 mRNA CTD PMID:28818685 GPER1 Human valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of GPER1 mRNA CTD PMID:29154799 GPER1 Human valproic acid increases methylation EXP 6480464 Valproic Acid results in increased methylation of GPER1 gene CTD PMID:29154799 GPER1 Human vinclozolin increases expression ISO Gper1 (Rattus norvegicus) 6480464 vinclozolin results in increased expression of GPER1 mRNA CTD PMID:23869203 GPER1 Human vinclozolin decreases expression ISO Gper1 (Mus musculus) 6480464 vinclozolin results in decreased expression of GPER1 mRNA and vinclozolin results in decreased expression of GPER1 protein CTD PMID:36642194 GPER1 Human wortmannin multiple interactions EXP 6480464 Wortmannin inhibits the reaction [tetrachlorodian results in increased expression of GPER1 mRNA] CTD PMID:36190352 GPER1 Human zearalenone affects binding EXP 6480464 Zearalenone binds to GPER1 protein CTD PMID:17088055 GPER1 Human zearalenone decreases expression EXP 6480464 Zearalenone results in decreased expression of GPER1 mRNA CTD PMID:28965971
