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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735664
Species: Homo sapiens
RGD Object: Gene
Symbol: GPER1
Name: G protein-coupled estrogen receptor 1
Acc ID: CHEBI:38530
Term: quinazolines
Definition: Any organic heterobicyclic compound based on a quinazoline skeleton and its substituted derivatives.
Chemical ID: MESH:D011799
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GPER1multiple interactionsISOGper1 (Rattus norvegicus)6480464CTDQuinazolines inhibits the reaction [[1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone binds to and results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 protein]PMID:22645130
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