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Gene: Gper1 (G protein-coupled estrogen receptor 1) Mus musculus
Symbol: Gper1
Name: G protein-coupled estrogen receptor 1
Description: Exhibits estrogen receptor activity. Involved in several processes, including cellular chemical homeostasis; cellular response to estradiol stimulus; and positive regulation of cell communication. Localizes to the cytoplasm; hippocampal mossy fiber to CA3 synapse; and plasma membrane. Is expressed in embryo; metanephros; and pituitary gland. Orthologous to human GPER1 (G protein-coupled estrogen receptor 1); PARTICIPATES IN bisphenol A response pathway; estrogen signaling pathway; G protein mediated signaling pathway via Galphas family; INTERACTS WITH 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6330420K13Rik; Ceprl; chemoattractant receptor-like 2; CMKRL2; constitutively expressed peptide-like receptor like; FEG-1; G protein-coupled receptor 30; G-protein coupled estrogen receptor 1; G-protein coupled receptor 30; GPCR-Br; Gper; Gpr30; membrane estrogen receptor; mER
Homo sapiens (human) : GPER1 (G protein-coupled estrogen receptor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gper1 (G protein-coupled estrogen receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gper1 (G protein-coupled estrogen receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GPER1 (G protein-coupled estrogen receptor 1)
Canis lupus familiaris (dog) : GPER1 (G protein-coupled estrogen receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gper1 (G protein-coupled estrogen receptor 1)
Sus scrofa (pig) : GPER1 (G protein-coupled estrogen receptor 1)
Chlorocebus sabaeus (African green monkey) : GPER1 (G protein-coupled estrogen receptor 1)
Heterocephalus glaber (naked mole-rat) : Gper1 (G protein-coupled estrogen receptor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl5139,423,151 - 139,427,800 (+)Ensembl
GRCm385139,423,150 - 139,427,800 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375139,899,133 - 139,903,754 (+)NCBIGRCm37mm9NCBIm37
MGSCv365139,676,821 - 139,681,430 (+)NCBImm8
Celera5136,477,197 - 136,481,822 (+)NCBICelera
Cytogenetic Map5 G2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Gper1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731530
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-12-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.