Gene: CACNA1I (calcium voltage-gated channel subunit alpha1 I) Homo sapiens
Symbol: CACNA1I
Name: calcium voltage-gated channel subunit alpha1 I
Description: This gene encodes the pore-forming alpha subunit of a voltage gated calcium channel. The encoded protein is a member of a subfamily of calcium channels referred to as is a low voltage-activated, T-type, calcium channel. The channel encoded by this protein is characterized by a slower activation and inactivation compared to other T-type calcium channels. This protein may be involved in calcium signaling in neurons. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ca(v)3.3; calcium channel, voltage-dependent, alpha 1I subunit; calcium channel, voltage-dependent, T type, alpha 1I subunit; Cav3.3; KIAA1120; OTTHUMP00000199122; OTTHUMP00000199123; OTTHUMP00000199124; OTTHUMP00000199125; voltage-dependent T-type calcium channel subunit alpha-1I; voltage-gated calcium channel subunit alpha Cav3.3
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh382239,570,753 - 39,689,737 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372239,966,758 - 40,085,740 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362238,296,704 - 38,415,686 (+)NCBINCBI36hg18NCBI36
Build 342238,291,257 - 38,410,238NCBI
Celera2223,768,830 - 23,887,794 (+)NCBI
Cytogenetic Map22q13.1NCBI
HuRef2222,931,166 - 23,048,848 (+)NCBIHuRef
CHM1_12239,925,499 - 40,044,841 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CACNA1I
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68996
Created: 2001-11-06
Species: Homo sapiens
Last Modified: 2019-02-19
Status: ACTIVE