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ONTOLOGY REPORT - ANNOTATIONS

Term:cytokine production involved in immune response
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Accession:GO:0002367 term browser browse the term
Definition:The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels.
Comment:Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
Synonyms:narrow_synonym: cytokine biosynthetic process involved in immune response
 related_synonym: cytokine production during immune response;   cytokine secretion during immune response;   cytokine secretion involved in immune response
 alt_id: GO:0002374;   GO:0002375


show annotations for term's descendants           Sort by:
negative regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:20060382)		 Ensembl
RGD		 PMID:20060382 GO_REF:0000107 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Apoa1 apolipoprotein A1 involved_in ISO
IEA		 (PMID:12458630)
GO_REF:0000107		 RGD
Ensembl		 PMID:12458630 GO_REF:0000107 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:12458630) RGD PMID:12458630 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355 		JBrowse link
G Il10 interleukin 10 involved_in ISS
ISO		 GO_REF:0000024
(PMID:10443688)		 UniProt
RGD		 PMID:10443688 GO_REF:0000024 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:10443688) RGD PMID:10443688 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
negative regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jak3 Janus kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16020505)		 BHF-UCL
RGD		 PMID:16020505 GO_REF:0000024 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
negative regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2180086 (PMID:11168643)		 Ensembl
RGD		 PMID:11168643 GO_REF:0000107 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Atg9a autophagy related 9A acts_upstream_of_or_within ISO (PMID:24670807) RGD PMID:24670807 NCBI chr 9:76,677,403...76,688,050
Ensembl chr 9:76,677,404...76,687,986 		JBrowse link
G Axl Axl receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:107670 (PMID:16831897) RGD PMID:16831897 NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265 		JBrowse link
G Cuedc2 CUE domain containing 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24882011)
MGI:5635142 (PMID:24882011)
GO_REF:0000107		 RGD
Ensembl		 PMID:24882011 GO_REF:0000107 NCBI chr 1:245,192,057...245,200,594
Ensembl chr 1:245,192,063...245,200,339 		JBrowse link
G Epx eosinophil peroxidase acts_upstream_of_or_within ISO MGI:2182952 (PMID:16926417) RGD PMID:16926417 NCBI chr10:72,666,865...72,677,952
Ensembl chr10:72,666,865...72,677,952 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in ISO (PMID:12150927) RGD PMID:12150927 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Nlrx1 NLR family member X1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:5141085 (PMID:21703540)		 Ensembl
RGD		 PMID:21703540 GO_REF:0000107 NCBI chr 8:44,588,476...44,606,678
Ensembl chr 8:44,590,048...44,606,484 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:2680581 (PMID:15220916) RGD PMID:15220916 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Prg2 proteoglycan 2, pro eosinophil major basic protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3027719 (PMID:16926417)		 Ensembl
RGD		 PMID:16926417 GO_REF:0000107 NCBI chr 3:70,062,535...70,066,102
Ensembl chr 3:70,062,535...70,066,101 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS		 (PMID:20875417)
GO_REF:0000024		 RGD
AgBase		 PMID:20875417 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20875417)		 AgBase
RGD		 PMID:20875417 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISO
ISS		 (PMID:20875417)
GO_REF:0000024		 RGD
AgBase		 PMID:20875417 GO_REF:0000024 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:104685 (PMID:16831897) RGD PMID:16831897 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
G Twist2 twist family bHLH transcription factor 2 acts_upstream_of_or_within ISO MGI:3044412|MGI:98872 (PMID:16831897) RGD PMID:16831897 NCBI chr 9:92,374,740...92,419,222
Ensembl chr 9:92,374,574...92,419,222 		JBrowse link
negative regulation of mast cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:2158436 (PMID:15950739) RGD PMID:15950739 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:17234154 RGD:1601626 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO MGI:3051384 (PMID:16533754) RGD PMID:16533754 NCBI chr12:26,459,190...26,503,790
Ensembl chr12:26,460,175...26,503,744 		JBrowse link
negative regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd96 CD96 molecule acts_upstream_of_or_within ISO MGI:5617136 (PMID:24658051) RGD PMID:24658051 NCBI chr11:54,702,290...54,776,618
Ensembl chr11:54,702,290...54,776,621 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
negative regulation of plasmacytoid dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bst2 bone marrow stromal cell antigen 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19564354)		 UniProt
RGD		 PMID:19564354 GO_REF:0000024 NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979 		JBrowse link
negative regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 involved_in ISO (PMID:15466453), (PMID:23169781) RGD PMID:15466453 PMID:23169781 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Hfe homeostatic iron regulator involved_in ISO UniProtKB:P04439 (PMID:24643698) RGD PMID:24643698 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:18420485) RGD PMID:18420485 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (PMID:11477403) RGD PMID:11477403 NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497 		JBrowse link
G Smad7 SMAD family member 7 involved_in IEA
ISO		 GO_REF:0000107
(PMID:25642768)		 Ensembl
RGD		 PMID:25642768 GO_REF:0000107 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Vsir V-set immunoregulatory receptor acts_upstream_of_or_within ISO (PMID:21383057) RGD PMID:21383057 NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:10887101) RGD PMID:10887101 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
negative regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19360123)		 Ensembl
RGD		 PMID:19360123 GO_REF:0000107 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (PMID:20554961) RGD PMID:20554961 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (PMID:10761931), (PMID:23616576) RGD PMID:10761931 PMID:23616576 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831 		JBrowse link
positive regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec7a C-type lectin domain containing 7A involved_in IBA
ISO		 GO_REF:0000033
(PMID:27288407)		 GO_Central
RGD		 PMID:27288407 GO_REF:0000033 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Defb43 defensin beta 43 involved_in ISO (PMID:26649771) RGD PMID:26649771 NCBI chr15:37,271,888...37,276,782
Ensembl chr15:37,272,008...37,276,626 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11441110)		 UniProt
RGD		 PMID:11441110 GO_REF:0000024 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Ffar2 free fatty acid receptor 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23665276)		 UniProt
RGD		 PMID:23665276 GO_REF:0000024 NCBI chr 1:86,071,855...86,075,049
Ensembl chr 1:86,072,184...86,075,033 		JBrowse link
G Ffar3 free fatty acid receptor 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23665276)		 UniProt
RGD		 PMID:23665276 GO_REF:0000024 NCBI chr 1:86,105,388...86,106,728
Ensembl chr 1:86,104,920...86,106,849 		JBrowse link
G Hk1 hexokinase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:27374331)		 Ensembl
RGD		 PMID:27374331 GO_REF:0000107 NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IMP RGD PMID:19318092 RGD:401901206 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Inava innate immunity activator involved_in ISO (PMID:28436939) RGD PMID:28436939 NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729 		JBrowse link
G Irf5 interferon regulatory factor 5 involved_in ISO (PMID:29046356) RGD PMID:29046356 NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267 		JBrowse link
G Lacc1 laccase domain containing 1 involved_in ISO (PMID:28593945) RGD PMID:28593945 NCBI chr15:52,390,267...52,407,630
Ensembl chr15:52,395,183...52,407,545 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:22733818) RGD PMID:22733818 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in ISO (PMID:27374331) RGD PMID:27374331 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO (PMID:16260731) RGD PMID:16260731 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:27288407) RGD PMID:27288407 NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (PMID:17346996) RGD PMID:17346996 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
G Tek TEK receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:20060382) RGD PMID:20060382 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:4940320 (PMID:21236258)		 GO_Central
RGD		 PMID:21236258 GO_REF:0000033 NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703 		JBrowse link
G Trim6 tripartite motif containing 6 involved_in ISO (PMID:24882218) RGD PMID:24882218 NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:18174455) RGD PMID:18174455 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
positive regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec7a C-type lectin domain containing 7A involved_in ISO (PMID:19136564), (PMID:27288407) RGD PMID:19136564 PMID:27288407 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO (PMID:18454155) RGD PMID:18454155 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 IDA RGD PMID:16818757 RGD:1600784 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19136564)		 Ensembl
RGD		 PMID:19136564 GO_REF:0000107 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:27288407) RGD PMID:27288407 NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171 		JBrowse link
positive regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card9 caspase recruitment domain family, member 9 acts_upstream_of_or_within ISO MGI:3698412 (PMID:17187069) RGD PMID:17187069 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Casp1 caspase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:18490713)		 Ensembl
RGD		 PMID:18490713 GO_REF:0000107 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp4 caspase 4 acts_upstream_of_or_within ISO MGI:1931465|MGI:2653833 (PMID:22002608) RGD PMID:22002608 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Cd36 CD36 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2447190|MGI:3573941 (PMID:15690042), (PMID:16061696)		 Ensembl
RGD		 PMID:15690042 PMID:16061696 GO_REF:0000107 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd74 CD74 molecule involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:19413900)
GO_REF:0000033		 BHF-UCL
RGD
GO_Central		 PMID:19413900 GO_REF:0000024 GO_REF:0000033 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Gprc5b G protein-coupled receptor, class C, group 5, member B involved_in ISO (PMID:23169819) RGD PMID:23169819 NCBI chr 1:173,316,904...173,340,933
Ensembl chr 1:173,316,907...173,340,932 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:9348310) RGD PMID:9348310 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:22733818) RGD PMID:22733818 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 acts_upstream_of_or_within ISO (PMID:24020373) RGD PMID:24020373 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457 		JBrowse link
G Mir324 microRNA 324 acts_upstream_of_or_within ISO (PMID:24882011) RGD PMID:24882011 NCBI chr10:54,734,680...54,734,762
Ensembl chr10:54,734,678...54,734,766 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of_or_within ISO MGI:2147032|MGI:2385681 (PMID:10607756), (PMID:11067888), (PMID:12872135) RGD PMID:10607756 PMID:11067888 PMID:12872135 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of_or_within ISO MGI:2429397|MGI:2674231 (PMID:18261938) RGD PMID:18261938 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:1341839|MGI:2680581|MGI:3529594 (PMID:14560001), (PMID:15220916), (PMID:15692051), (PMID:18261938) RGD PMID:14560001 PMID:15220916 PMID:15692051 PMID:18261938 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:2386080|MGI:3606250 (PMID:11016935), (PMID:18490713) RGD PMID:11016935 PMID:18490713 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Panx1 Pannexin 1 acts_upstream_of_or_within ISO (PMID:18490713) RGD PMID:18490713 NCBI chr 8:11,851,176...11,889,774
Ensembl chr 8:11,850,730...11,889,774 		JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
(PMID:22041900)		 Ensembl
RGD		 PMID:22041900 GO_REF:0000107 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Pycard PYD and CARD domain containing acts_upstream_of_or_within ISO MGI:107700|MGI:2653833 (PMID:22002608) RGD PMID:22002608 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO MGI:2660793 (PMID:11894098), (PMID:18261938) RGD PMID:11894098 PMID:18261938 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:19304799) RGD PMID:19304799 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
G Rtn4 reticulon 4 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19805174)		 UniProt
RGD		 PMID:19805174 GO_REF:0000024 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686 		JBrowse link
G Sema7a semaphorin 7A (John Milton Hagen blood group) involved_in ISO (PMID:17377534) RGD PMID:17377534 NCBI chr 8:58,348,448...58,370,536
Ensembl chr 8:58,348,448...58,370,536 		JBrowse link
G Sirt1 sirtuin 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:22315447)		 Ensembl
RGD		 PMID:22315447 GO_REF:0000107 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Spon2 spondin 2 acts_upstream_of_or_within ISO MGI:3026870 (PMID:14691481) RGD PMID:14691481 NCBI chr14:77,505,695...77,518,001
Ensembl chr14:77,511,901...77,517,996 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO MGI:108005|MGI:2679794|MGI:3029019 (PMID:12855817), (PMID:12872135) RGD PMID:12855817 PMID:12872135 NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Tirap TIR domain containing adaptor protein acts_upstream_of_or_within ISO MGI:3573942 (PMID:15690042) RGD PMID:15690042 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO MGI:2178675|MGI:2674036 (PMID:10549626), (PMID:11067888), (PMID:15690042), (PMID:18261938) RGD PMID:10549626 PMID:11067888 PMID:15690042 PMID:18261938 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr3 toll-like receptor 3 acts_upstream_of_or_within ISO MGI:3690535 (PMID:12855817), (PMID:18261938) RGD PMID:12855817 PMID:18261938 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857718|MGI:1860755|MGI:1860885 (PMID:10549626), (PMID:10607756), (PMID:10623794), (PMID:14691481), (PMID:15661922), (PMID:18261938), (PMID:21609717)		 Ensembl
RGD		 PMID:10549626 PMID:10607756 PMID:10623794 PMID:14691481 PMID:15661922 More... GO_REF:0000107 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr7 toll-like receptor 7 acts_upstream_of_or_within ISO (PMID:18261938) RGD PMID:18261938 NCBI chr  X:27,027,380...27,054,309
Ensembl chr  X:27,027,425...27,054,754 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO
IEA		 (PMID:18174455)
GO_REF:0000107		 RGD
Ensembl		 PMID:18174455 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
positive regulation of mast cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1a Fc epsilon receptor Ia acts_upstream_of_or_within ISO (PMID:9000133) RGD PMID:9000133 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351 		JBrowse link
G Fcer1g Fc epsilon receptor Ig acts_upstream_of_or_within ISO MGI:2384004 (PMID:14764707) RGD PMID:14764707 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO (PMID:20100931) RGD PMID:20100931 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24586680)		 UniProt
RGD		 PMID:24586680 GO_REF:0000024 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2384078 (PMID:9000133)		 Ensembl
RGD		 PMID:9000133 GO_REF:0000107 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
positive regulation of myeloid dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk4 calcium/calmodulin-dependent protein kinase IV NOT|involved_in ISO (PMID:17909078) RGD PMID:17909078 NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487 		JBrowse link
G Ddx1 DEAD-box helicase 1 involved_in ISO (PMID:21703541) RGD PMID:21703541 NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365 		JBrowse link
G Ddx21 DExD-box helicase 21 involved_in ISO (PMID:21703541) RGD PMID:21703541 NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543 		JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO (PMID:21703541) RGD PMID:21703541 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:21703541)		 UniProt
RGD		 PMID:21703541 GO_REF:0000024 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Rig1 RNA sensor RIG-1 involved_in ISO (PMID:21703541) RGD PMID:21703541 NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 involved_in ISO (PMID:21703541) RGD PMID:21703541 NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
positive regulation of myeloid leukocyte cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:11756671) RGD PMID:11756671 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
positive regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd160 CD160 molecule involved_in ISO (PMID:17307798) RGD PMID:17307798 NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834 		JBrowse link
G Cd226 CD226 molecule acts_upstream_of_or_within ISO MGI:4454325 (PMID:24658051) RGD PMID:24658051 NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051 		JBrowse link
G Clnk cytokine-dependent hematopoietic cell linker involved_in ISO (PMID:16439675) RGD PMID:16439675 NCBI chr14:71,923,894...72,101,180
Ensembl chr14:71,873,105...72,101,208 		JBrowse link
G Gimap5 GTPase, IMAP family member 5 IMP RGD PMID:15100275 RGD:2303778 NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086 		JBrowse link
G Il21 interleukin 21 acts_upstream_of_or_within ISO (PMID:14764669) RGD PMID:14764669 NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:30134159) RGD PMID:30134159 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:27455421) RGD PMID:27455421 NCBI chr20:3,403,418...3,479,476 JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:16366734), (PMID:19304799), (PMID:23184984) RGD PMID:16366734 PMID:19304799 PMID:23184984 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
positive regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2 microglobulin involved_in ISO
IEA		 (PMID:24643698)
GO_REF:0000107		 RGD
Ensembl		 PMID:24643698 GO_REF:0000107 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:16818763) RGD PMID:16818763 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831 		JBrowse link
G Cd7 Cd7 molecule involved_in ISO (PMID:10652336) RGD PMID:10652336 NCBI chr10:106,304,046...106,306,963
Ensembl chr10:106,304,056...106,306,967 		JBrowse link
G Fzd5 frizzled class receptor 5 involved_in ISO
IEA		 (PMID:16601243)
GO_REF:0000107		 RGD
Ensembl		 PMID:16601243 GO_REF:0000107 NCBI chr 9:66,113,096...66,120,276
Ensembl chr 9:66,113,112...66,121,457 		JBrowse link
G Malt1 MALT1 paracaspase involved_in ISO (PMID:15125833) RGD PMID:15125833 NCBI chr18:58,942,282...58,996,318
Ensembl chr18:58,942,299...58,994,260 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in ISO (PMID:15125833) RGD PMID:15125833 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G RT1-CE16 RT1 class I, locus CE16 involved_in ISO (PMID:24643698) RGD PMID:24643698 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
G Sash3 SAM and SH3 domain containing 3 acts_upstream_of_or_within ISO MGI:3716944 (PMID:16227612) RGD PMID:16227612 NCBI chr  X:127,326,815...127,341,521
Ensembl chr  X:127,326,859...127,341,519 		JBrowse link
G Sectm1b secreted and transmembrane 1B involved_in ISO (PMID:22184754) RGD PMID:22184754 NCBI chr10:106,324,070...106,333,779
Ensembl chr10:106,325,203...106,333,769 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:18354165), (PMID:9670042) RGD PMID:9670042 PMID:18354165 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in ISO (PMID:15125833) RGD PMID:15125833 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO
IEA		 (PMID:15125833)
GO_REF:0000107		 RGD
Ensembl		 PMID:15125833 GO_REF:0000107 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:9029087) RGD PMID:9029087 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
positive regulation of T-helper 1 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid5a AT-rich interaction domain 5A involved_in ISO (PMID:27671645) RGD PMID:27671645 NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597 		JBrowse link
G Il18 interleukin 18 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:10653850)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:10653850 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il18r1 interleukin 18 receptor 1 involved_in ISO (PMID:10653850) RGD PMID:10653850 NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO
ISS		 (PMID:10653850)
GO_REF:0000024		 RGD
UniProt		 PMID:10653850 GO_REF:0000024 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 involved_in ISO
ISS
IEA		 (PMID:10653850)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:10653850 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937 		JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (PMID:9126961) RGD PMID:9126961 NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (PMID:10761931) RGD PMID:10761931 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:9973465)		 Ensembl
RGD		 PMID:9973465 GO_REF:0000107 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
positive regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 Cd81 molecule involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:8766544)
GO_REF:0000107
(PMID:11046035)		 UniProt
RGD
Ensembl		 PMID:8766544 PMID:11046035 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660 		JBrowse link
G Dennd1b DENN domain containing 1B involved_in ISO (PMID:26774822) RGD PMID:26774822 NCBI chr13:50,545,324...50,772,922
Ensembl chr13:50,545,836...50,770,601 		JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO (PMID:15087456) RGD PMID:15087456 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Il4 interleukin 4 involved_in ISO (PMID:20554961) RGD PMID:20554961 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:11159963) RGD PMID:11159963 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in ISO (PMID:26098997) RGD PMID:26098997 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Prkcz protein kinase C, zeta involved_in ISS
ISO		 GO_REF:0000024
(PMID:15987782)		 UniProt
RGD		 PMID:15987782 GO_REF:0000024 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:19047684)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19047684 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:9973465)		 Ensembl
RGD		 PMID:9973465 GO_REF:0000107 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg5 autophagy related 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:22710871)		 Ensembl
RGD		 PMID:22710871 GO_REF:0000107 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Pkp3 plakophilin 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:26173741)		 Ensembl
RGD		 PMID:26173741 GO_REF:0000107 NCBI chr 1:196,187,914...196,198,843
Ensembl chr 1:196,187,835...196,198,844 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO UniProtKB:Q9Z0D9 (PMID:28052249) RGD PMID:28052249 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Tril TLR4 interactor with leucine-rich repeats involved_in ISO
IBA		 (PMID:19710467)
GO_REF:0000033		 RGD
GO_Central		 PMID:19710467 GO_REF:0000033 NCBI chr 4:82,922,327...82,927,172
Ensembl chr 4:82,922,328...82,927,172 		JBrowse link
regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO (PMID:19047410) RGD PMID:19047410 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr3 toll-like receptor 3 acts_upstream_of_or_within ISO (PMID:19047410) RGD PMID:19047410 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:19047410)		 Ensembl
RGD		 PMID:19047410 GO_REF:0000107 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr9 toll-like receptor 9 acts_upstream_of_or_within ISO (PMID:19047410) RGD PMID:19047410 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Litaf lipopolysaccharide-induced TNF factor acts_upstream_of_or_within ISO MGI:3687962 (PMID:16954198) RGD PMID:16954198 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763 		JBrowse link
G Ube2j1 ubiquitin-conjugating enzyme E2, J1 acts_upstream_of_or_within ISO MGI:109298 (PMID:24020373) RGD PMID:24020373 NCBI chr 5:47,422,476...47,441,476
Ensembl chr 5:47,422,587...47,441,461 		JBrowse link
regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calhm6 calcium homeostasis modulator family member 6 involved_in IEA
ISO		 GO_REF:0000107
(PMID:36861806)		 Ensembl
RGD		 PMID:36861806 GO_REF:0000107 NCBI chr20:26,095,591...26,097,336
Ensembl chr20:26,095,592...26,097,278 		JBrowse link
regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl20 C-C motif chemokine ligand 20 NOT|involved_in ISO (PMID:19050256) RGD PMID:19050256 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:28507030)		 UniProt
RGD		 PMID:28507030 GO_REF:0000024 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in IBA
ISO		 GO_REF:0000033
(PMID:28052249)		 GO_Central
RGD		 PMID:28052249 GO_REF:0000033 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 involved_in ISO
IEA
ISS		 (PMID:20656926)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20656926 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    immune system process 3002
      production of molecular mediator of immune response 247
        cytokine production involved in immune response 134
          B cell cytokine production + 0
          T cell cytokine production + 40
          dendritic cell cytokine production + 18
          myeloid leukocyte cytokine production + 60
          natural killer cell cytokine production + 10
          negative regulation of cytokine production involved in immune response + 36
          positive regulation of cytokine production involved in immune response + 92
          regulation of cytokine production involved in immune response + 134
Path 2
Term Annotations click to browse term
  biological_process 20069
    cellular process 19150
      metabolic process 11950
        biosynthetic process 8469
          macromolecule biosynthetic process 7495
            gene expression 7050
              cytokine production 913
                cytokine production involved in immune response 134
                  B cell cytokine production + 0
                  T cell cytokine production + 40
                  dendritic cell cytokine production + 18
                  myeloid leukocyte cytokine production + 60
                  natural killer cell cytokine production + 10
                  negative regulation of cytokine production involved in immune response + 36
                  positive regulation of cytokine production involved in immune response + 92
                  regulation of cytokine production involved in immune response + 134
paths to the root