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ONTOLOGY REPORT - ANNOTATIONS

Term:production of molecular mediator of immune response
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Accession:GO:0002440 term browser browse the term
Definition:The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels.
Comment:Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
Synonyms:related_synonym: production of cellular mediator of immune response


show annotations for term's descendants           Sort by:
antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals4 galectin 4 acts_upstream_of_or_within ISO (PMID:27427436) RGD PMID:27427436 NCBI chr 1:84,124,766...84,132,481
Ensembl chr 1:84,124,764...84,132,481 		JBrowse link
G Mmp7 matrix metallopeptidase 7 acts_upstream_of_or_within ISO (PMID:20056603) RGD PMID:20056603 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902 		JBrowse link
antibacterial peptide secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp7 matrix metallopeptidase 7 acts_upstream_of_or_within ISO (PMID:11248802) RGD PMID:11248802 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902 		JBrowse link
B cell affinity maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase acts_upstream_of_or_within ISO MGI:1856317 (PMID:7680896) RGD PMID:7680896 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G RT1-Bb RT1 class II, locus Bb involved_in ISO (MGI:4943414|PMID:1378867) RGD PMID:1378867 MGI:4943414 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
G Traf3ip2 Traf3 interacting protein 2 involved_in ISO MGI:3510784 (PMID:20543113) RGD PMID:20543113 NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667 		JBrowse link
biosynthetic process of antibacterial peptides active against Gram-negative bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elane elastase, neutrophil expressed involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100 		JBrowse link
biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of ISO MGI:3529594 (PMID:15692051) RGD PMID:15692051 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
immunoglobulin heavy chain V-D-J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Polb DNA polymerase beta acts_upstream_of_or_within ISO MGI:5427084 (PMID:24388753) RGD PMID:24388753 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812 		JBrowse link
G Yy1 YY1 transcription factor involved_in ISO MGI:3624790 (PMID:23531880) RGD PMID:23531880 NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747 		JBrowse link
immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkdc protein kinase, DNA-activated, catalytic subunit IMP RGD PMID:22981234 RGD:8696027 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
immunoglobulin V(D)J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyren cell cycle regulator of NHEJ involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:6202149|PMID:30017584), (MGI:6716972|PMID:31795137)		 UniProt
Ensembl
RGD		 PMID:30017584 PMID:31795137 GO_REF:0000024 GO_REF:0000107 MGI:6202149 MGI:6716972 NCBI chr 4:63,547,311...63,553,394
Ensembl chr 4:63,547,335...63,551,602 		JBrowse link
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO MGI:3711150 (PMID:16819554) RGD PMID:16819554 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Lig4 DNA ligase 4 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1857732 (PMID:9823897)		 GO_Central
RGD		 PMID:9823897 GO_REF:0000033 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040 		JBrowse link
G Nhej1 nonhomologous end-joining factor 1 involved_in ISO
IEA
ISS		 (PMID:20558749)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20558749 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:76,526,322...76,622,488
Ensembl chr 9:76,526,324...76,622,444 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:2383951 (PMID:9768755)		 GO_Central
RGD		 PMID:9768755 GO_REF:0000033 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Tcf3 transcription factor 3 acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (PMID:16428437)
MGI:2178112 (PMID:16428437)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:16428437 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:9,280,571...9,302,315
Ensembl chr 7:9,280,571...9,302,314 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1926771 (PMID:9875844)		 GO_Central
RGD		 PMID:9875844 GO_REF:0000033 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808 		JBrowse link
isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase involved_in
acts_upstream_of_or_within		 ISO (MGI:5004983|PMID:21518874)
(PMID:17713479)		 RGD PMID:17713479 PMID:21518874 MGI:5004983 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972 		JBrowse link
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of ISO MGI:4127920 (PMID:25404367) RGD PMID:25404367 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845 		JBrowse link
G Batf basic leucine zipper ATF-like transcription factor involved_in ISS
ISO		 GO_REF:0000024
(MGI:4456325|PMID:20421391), (MGI:5004732|PMID:21572431)		 UniProt
RGD		 PMID:20421391 PMID:21572431 GO_REF:0000024 MGI:4456325 MGI:5004732 NCBI chr 6:105,353,715...105,376,051
Ensembl chr 6:105,353,715...105,376,051 		JBrowse link
G Cd40lg CD40 ligand involved_in IEA
ISO		 GO_REF:0000107
(MGI:3687427|PMID:7529792)		 Ensembl
RGD		 PMID:7529792 GO_REF:0000107 MGI:3687427 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit acts_upstream_of_or_within ISO MGI:2183944 (PMID:15280420) RGD PMID:15280420 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Exo1 exonuclease 1 acts_upstream_of_or_within ISO MGI:2653925 (PMID:14716311) RGD PMID:14716311 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654 		JBrowse link
G Exosc3 exosome component 3 involved_in ISO (MGI:5009766|PMID:21255825) RGD PMID:21255825 MGI:5009766 NCBI chr 5:59,573,849...59,579,065
Ensembl chr 5:59,573,886...59,579,060 		JBrowse link
G Exosc6 exosome component 6 involved_in ISO (MGI:5009766|PMID:21255825) RGD PMID:21255825 MGI:5009766 NCBI chr19:39,022,171...39,023,585
Ensembl chr19:39,022,183...39,023,515 		JBrowse link
G Lig4 DNA ligase 4 acts_upstream_of_or_within ISO MGI:1857732 (PMID:17713479) RGD PMID:17713479 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040 		JBrowse link
G Mlh1 mutL homolog 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857946 (PMID:12743174)		 Ensembl
RGD		 PMID:12743174 GO_REF:0000107 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Msh2 mutS homolog 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857940|MGI:2151801 (PMID:10430621), (PMID:12743174)		 Ensembl
RGD		 PMID:10430621 PMID:12743174 GO_REF:0000107 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within ISO MGI:109352|MGI:3653701 (PMID:16618598), (PMID:17015724) RGD PMID:16618598 PMID:17015724 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956 		JBrowse link
G Nbn nibrin involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:3529405|PMID:15668383)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:15668383 GO_REF:0000024 GO_REF:0000107 MGI:3529405 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO MGI:3046930|MGI:5501251 (PMID:25124037), (PMID:31182790) RGD PMID:25124037 PMID:31182790 NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723 		JBrowse link
G Pcyt1a phosphate cytidylyltransferase 1A, choline involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr11:68,313,860...68,357,828
Ensembl chr11:68,313,882...68,357,357 		JBrowse link
G Rnf168 ring finger protein 168 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4420833|PMID:20080757)		 UniProt
RGD		 PMID:20080757 GO_REF:0000024 MGI:4420833 NCBI chr11:68,486,313...68,508,296
Ensembl chr11:68,486,321...68,508,277 		JBrowse link
G Rnf8 ring finger protein 8 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4420833|PMID:20080757)		 UniProt
RGD		 PMID:20080757 GO_REF:0000024 MGI:4420833 NCBI chr20:7,682,258...7,710,448
Ensembl chr20:7,682,322...7,708,491 		JBrowse link
G Sanbr SANT and BTB domain regulator of CSR involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:6707280|PMID:33831416)		 UniProt
Ensembl
RGD		 PMID:33831416 GO_REF:0000024 GO_REF:0000107 MGI:6707280 NCBI chr14:97,516,652...97,585,955
Ensembl chr14:97,516,413...97,581,346 		JBrowse link
G Swap70 switching B-cell complex subunit SWAP70 acts_upstream_of_or_within ISO (PMID:9642267) RGD PMID:9642267 NCBI chr 1:164,267,588...164,328,796
Ensembl chr 1:164,267,609...164,328,794 		JBrowse link
G Ung uracil-DNA glycosylase acts_upstream_of_or_within ISO MGI:1343961 (PMID:17015724) RGD PMID:17015724 NCBI chr12:42,485,276...42,494,217
Ensembl chr12:42,485,276...42,494,206 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO MGI:1926771|MGI:3047571|MGI:3641440 (PMID:17713479) RGD PMID:17713479 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808 		JBrowse link
isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr6 C-C motif chemokine receptor 6 involved_in ISO (MGI:5787846|PMID:27174992) RGD PMID:27174992 MGI:5787846 NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603 		JBrowse link
isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of ISO MGI:103034|MGI:2158438 (PMID:10490661) RGD PMID:10490661 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of ISO MGI:3696705 (PMID:16275384) RGD PMID:16275384 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Il4 interleukin 4 acts_upstream_of ISO (PMID:14988498) RGD PMID:14988498 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of ISO MGI:107187 (PMID:10490661) RGD PMID:10490661 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495 		JBrowse link
isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:16148103) RGD PMID:16148103 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Il4 interleukin 4 acts_upstream_of ISO (PMID:14988498) RGD PMID:14988498 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
negative regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spink5 serine peptidase inhibitor, Kazal type 5 involved_in ISO (MGI:3770082|PMID:17012259) RGD PMID:17012259 MGI:3770082 NCBI chr18:36,264,452...36,333,143
Ensembl chr18:36,264,452...36,332,185 		JBrowse link
negative regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:20060382)		 Ensembl
RGD		 PMID:20060382 GO_REF:0000107 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Apoa1 apolipoprotein A1 involved_in ISO
IEA		 (PMID:12458630)
GO_REF:0000107		 RGD
Ensembl		 PMID:12458630 GO_REF:0000107 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:12458630) RGD PMID:12458630 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355 		JBrowse link
G Il10 interleukin 10 involved_in ISS
ISO		 GO_REF:0000024
(PMID:10443688)		 UniProt
RGD		 PMID:10443688 GO_REF:0000024 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:10443688) RGD PMID:10443688 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
negative regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jak3 Janus kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3719947|PMID:16020505)		 BHF-UCL
RGD		 PMID:16020505 GO_REF:0000024 MGI:3719947 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
negative regulation of immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd22 CD22 molecule involved_in ISO UniProtKB:Q80ZE3 (MGI:4453395|PMID:20200274) RGD PMID:20200274 MGI:4453395 NCBI chr 1:86,116,376...86,132,782
Ensembl chr 1:86,117,459...86,132,322 		JBrowse link
G Fcgr2b Fc gamma receptor 2B acts_upstream_of_or_within ISO MGI:1857166 (PMID:12385742) RGD PMID:12385742 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Ifnb1 interferon beta 1 IDA RGD PMID:10494101 RGD:401854240 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2653910 (PMID:15944273)		 Ensembl
RGD		 PMID:15944273 GO_REF:0000107 NCBI chr  X:111,002,590...111,074,053
Ensembl chr  X:111,002,592...111,072,381 		JBrowse link
G Il33 interleukin 33 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P08226 (MGI:3775141|PMID:18268038)		 Ensembl
RGD		 PMID:18268038 GO_REF:0000107 MGI:3775141 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit IMP RGD PMID:22981234 RGD:8696027 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Siglec10 sialic acid binding Ig-like lectin 10 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 1:93,817,301...93,826,376
Ensembl chr 1:93,817,335...93,825,931 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO (MGI:3840374|PMID:19328063) RGD PMID:19328063 MGI:3840374 NCBI chr 7:130,527,313...130,542,567
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
G Zpbp2 zona pellucida binding protein 2 acts_upstream_of_or_within ISO MGI:3762590 (PMID:29536159) RGD PMID:29536159 NCBI chr10:83,558,772...83,567,511
Ensembl chr10:83,559,016...83,567,508 		JBrowse link
negative regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp3 poly (ADP-ribose) polymerase family, member 3 involved_in ISO (MGI:6214451|PMID:26000965) RGD PMID:26000965 MGI:6214451 NCBI chr 8:107,111,010...107,117,073
Ensembl chr 8:107,111,012...107,116,782 		JBrowse link
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:103034|MGI:2158438 (PMID:10490661) RGD PMID:10490661 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO MGI:3696705 (PMID:16275384) RGD PMID:16275384 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3695433 (PMID:17137798)		 Ensembl
RGD		 PMID:17137798 GO_REF:0000107 NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311 		JBrowse link
negative regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2180086 (PMID:11168643)		 Ensembl
RGD		 PMID:11168643 GO_REF:0000107 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Atg9a autophagy related 9A acts_upstream_of_or_within ISO (PMID:24670807) RGD PMID:24670807 NCBI chr 9:76,677,403...76,688,050
Ensembl chr 9:76,677,404...76,687,986 		JBrowse link
G Axl Axl receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:107670 (PMID:16831897) RGD PMID:16831897 NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265 		JBrowse link
G Cuedc2 CUE domain containing 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24882011)
MGI:5635142 (PMID:24882011)
GO_REF:0000107		 RGD
Ensembl		 PMID:24882011 GO_REF:0000107 NCBI chr 1:245,192,057...245,200,594
Ensembl chr 1:245,192,063...245,200,339 		JBrowse link
G Epx eosinophil peroxidase acts_upstream_of_or_within ISO MGI:2182952 (PMID:16926417) RGD PMID:16926417 NCBI chr10:72,666,865...72,677,952
Ensembl chr10:72,666,865...72,677,952 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in ISO (MGI:2183694|PMID:12150927) RGD PMID:12150927 MGI:2183694 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Nlrx1 NLR family member X1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:5141085 (PMID:21703540)		 Ensembl
RGD		 PMID:21703540 GO_REF:0000107 NCBI chr 8:44,588,476...44,606,678
Ensembl chr 8:44,590,048...44,606,484 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:2680581 (PMID:15220916) RGD PMID:15220916 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Prg2 proteoglycan 2, pro eosinophil major basic protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3027719 (PMID:16926417)		 Ensembl
RGD		 PMID:16926417 GO_REF:0000107 NCBI chr 3:70,062,535...70,066,102
Ensembl chr 3:70,062,535...70,066,101 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS		 (PMID:20875417)
GO_REF:0000024		 RGD
AgBase		 PMID:20875417 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20875417)		 AgBase
RGD		 PMID:20875417 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISO
ISS		 (PMID:20875417)
GO_REF:0000024		 RGD
AgBase		 PMID:20875417 GO_REF:0000024 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:104685 (PMID:16831897) RGD PMID:16831897 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
G Twist2 twist family bHLH transcription factor 2 acts_upstream_of_or_within ISO MGI:3044412|MGI:98872 (PMID:16831897) RGD PMID:16831897 NCBI chr 9:92,374,740...92,419,222
Ensembl chr 9:92,374,574...92,419,222 		JBrowse link
negative regulation of mast cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:2158436 (PMID:15950739) RGD PMID:15950739 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:17234154 RGD:1601626 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO MGI:3051384 (PMID:16533754) RGD PMID:16533754 NCBI chr12:26,459,190...26,503,790
Ensembl chr12:26,460,175...26,503,744 		JBrowse link
negative regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd96 CD96 molecule acts_upstream_of_or_within ISO MGI:5617136 (PMID:24658051) RGD PMID:24658051 NCBI chr11:54,702,290...54,776,618
Ensembl chr11:54,702,290...54,776,621 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
negative regulation of plasmacytoid dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bst2 bone marrow stromal cell antigen 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19564354)		 UniProt
RGD		 PMID:19564354 GO_REF:0000024 NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979 		JBrowse link
negative regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 involved_in ISO (PMID:15466453), (PMID:23169781) RGD PMID:15466453 PMID:23169781 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Hfe homeostatic iron regulator involved_in ISO UniProtKB:P04439 (PMID:24643698) RGD PMID:24643698 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:18420485) RGD PMID:18420485 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (MGI:5700313|PMID:11477403) RGD PMID:11477403 MGI:5700313 NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497 		JBrowse link
G Smad7 SMAD family member 7 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5634593|PMID:25642768)		 Ensembl
RGD		 PMID:25642768 GO_REF:0000107 MGI:5634593 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Vsir V-set immunoregulatory receptor acts_upstream_of_or_within ISO (PMID:21383057) RGD PMID:21383057 NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:10887101) RGD PMID:10887101 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
negative regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in ISO
IEA		 (MGI:5908339|PMID:19360123)
GO_REF:0000107		 RGD
Ensembl		 PMID:19360123 GO_REF:0000107 MGI:5908339 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (PMID:20554961) RGD PMID:20554961 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:1354779|PMID:10761931), (MGI:5543347|PMID:23616576) RGD PMID:10761931 PMID:23616576 MGI:1354779 MGI:5543347 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831 		JBrowse link
positive regulation of antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:18167348) RGD PMID:18167348 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
positive regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klk1c10 kallikrein 1-related peptidase C10 involved_in ISO (PMID:18714013) RGD PMID:18714013 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052 		JBrowse link
G Klk5 kallikrein related-peptidase 5 involved_in ISO
IBA		 (PMID:17012259)
GO_REF:0000033		 RGD
GO_Central		 PMID:17012259 GO_REF:0000033 NCBI chr 1:94,296,574...94,304,768
Ensembl chr 1:94,296,168...94,304,666 		JBrowse link
G Klk7 kallikrein-related peptidase 7 involved_in IEA
ISO		 GO_REF:0000107
(PMID:17012259)		 Ensembl
RGD		 PMID:17012259 GO_REF:0000107 NCBI chr 1:94,267,170...94,271,361
Ensembl chr 1:94,266,605...94,271,332 		JBrowse link
G Pgc progastricsin involved_in ISO (PMID:12759353) RGD PMID:12759353 NCBI chr 9:13,257,462...13,265,682
Ensembl chr 9:13,257,462...13,265,682 		JBrowse link
positive regulation of antimicrobial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il17a interleukin 17A involved_in IEA
ISO		 GO_REF:0000107
(MGI:3828868|PMID:19144317)		 Ensembl
RGD		 PMID:19144317 GO_REF:0000107 MGI:3828868 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il17f interleukin 17F involved_in IEA
ISO		 GO_REF:0000107
(MGI:3828868|PMID:19144317)		 Ensembl
RGD		 PMID:19144317 GO_REF:0000107 MGI:3828868 NCBI chr 9:23,190,094...23,201,482
Ensembl chr 9:23,190,100...23,201,482 		JBrowse link
positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:3529594 (PMID:15692051) RGD PMID:15692051 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
positive regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec7a C-type lectin domain containing 7A involved_in ISO
IBA		 (MGI:5803730|PMID:27288407)
GO_REF:0000033		 RGD
GO_Central		 PMID:27288407 GO_REF:0000033 MGI:5803730 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Defb43 defensin beta 43 involved_in ISO (PMID:26649771) RGD PMID:26649771 NCBI chr15:37,271,888...37,276,782
Ensembl chr15:37,272,008...37,276,626 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11441110)		 UniProt
RGD		 PMID:11441110 GO_REF:0000024 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Ffar2 free fatty acid receptor 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5575446|PMID:23665276)		 UniProt
RGD		 PMID:23665276 GO_REF:0000024 MGI:5575446 NCBI chr 1:86,071,855...86,075,049
Ensembl chr 1:86,072,184...86,075,033 		JBrowse link
G Ffar3 free fatty acid receptor 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5575446|PMID:23665276)		 UniProt
RGD		 PMID:23665276 GO_REF:0000024 MGI:5575446 NCBI chr 1:86,105,388...86,106,728
Ensembl chr 1:86,104,920...86,106,849 		JBrowse link
G Hk1 hexokinase 1 involved_in ISO
IEA		 (MGI:5790524|PMID:27374331)
GO_REF:0000107		 RGD
Ensembl		 PMID:27374331 GO_REF:0000107 MGI:5790524 NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IMP RGD PMID:19318092 RGD:401901206 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Inava innate immunity activator involved_in ISO (PMID:28436939) RGD PMID:28436939 NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729 		JBrowse link
G Irf5 interferon regulatory factor 5 involved_in ISO (PMID:29046356) RGD PMID:29046356 NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267 		JBrowse link
G Lacc1 laccase domain containing 1 involved_in ISO (PMID:28593945) RGD PMID:28593945 NCBI chr15:52,390,267...52,407,630
Ensembl chr15:52,395,183...52,407,545 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:6391873|PMID:22733818) RGD PMID:22733818 MGI:6391873 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in ISO (MGI:5790524|PMID:27374331) RGD PMID:27374331 MGI:5790524 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO (PMID:16260731) RGD PMID:16260731 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (MGI:5803730|PMID:27288407) RGD PMID:27288407 MGI:5803730 NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (MGI:3703830|PMID:17346996) RGD PMID:17346996 MGI:3703830 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
G Tek TEK receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:20060382) RGD PMID:20060382 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:4940320 (PMID:21236258)		 GO_Central
RGD		 PMID:21236258 GO_REF:0000033 NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703 		JBrowse link
G Trim6 tripartite motif containing 6 involved_in ISO (PMID:24882218) RGD PMID:24882218 NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:18174455) RGD PMID:18174455 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
positive regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec7a C-type lectin domain containing 7A involved_in ISO (MGI:3844414|PMID:19136564), (MGI:5803730|PMID:27288407) RGD PMID:19136564 PMID:27288407 MGI:3844414 MGI:5803730 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO (MGI:3796803|PMID:18454155) RGD PMID:18454155 MGI:3796803 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 IDA RGD PMID:16818757 RGD:1600784 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3844414|PMID:19136564)		 Ensembl
RGD		 PMID:19136564 GO_REF:0000107 MGI:3844414 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (MGI:5803730|PMID:27288407) RGD PMID:27288407 MGI:5803730 NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171 		JBrowse link
positive regulation of granzyme A production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:18832695) RGD PMID:18832695 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
positive regulation of granzyme B production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd244 CD244 molecule involved_in ISO (PMID:11714776) RGD PMID:11714776 NCBI chr13:84,051,339...84,082,864
Ensembl chr13:84,052,493...84,074,492 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (MGI:5562517|PMID:23871208) RGD PMID:23871208 MGI:5562517 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:18832695) RGD PMID:18832695 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
positive regulation of immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase IMP RGD PMID:28352114 RGD:151665126 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Cd37 CD37 molecule acts_upstream_of_or_within ISO MGI:2386160 (PMID:10891477) RGD PMID:10891477 NCBI chr 1:95,719,171...95,724,662
Ensembl chr 1:95,719,190...95,724,648 		JBrowse link
G Cd86 CD86 molecule involved_in ISO (MGI:5461234|PMID:23241883) RGD PMID:23241883 MGI:5461234 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 involved_in ISO (MGI:3777853|PMID:12023368) RGD PMID:12023368 MGI:3777853 NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5644772|PMID:25222125)		 UniProt
RGD		 PMID:25222125 GO_REF:0000024 MGI:5644772 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063 		JBrowse link
G Ephb2 Eph receptor B2 involved_in ISO (PMID:24803541) RGD PMID:24803541 NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059 		JBrowse link
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO MGI:3711150 (PMID:16819554) RGD PMID:16819554 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Gpi glucose-6-phosphate isomerase involved_in ISO (PMID:3020690) RGD PMID:3020690 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086 		JBrowse link
G Hpx hemopexin acts_upstream_of_or_within ISO MGI:2447193 (PMID:18641331) RGD PMID:18641331 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328 		JBrowse link
G Il10 interleukin 10 acts_upstream_of ISO UniProtKB:P60568 (PMID:22962438) RGD PMID:22962438 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il13 interleukin 13 acts_upstream_of_or_within IDA
ISO		 IgE production after infection
MGI:1931804|MGI:96556 (PMID:15944273)		 RGD PMID:15944273 PMID:11573960 RGD:633067 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 IDA IgE production after infection RGD PMID:11573960 RGD:633067 NCBI chr  X:115,348,822...115,408,682
Ensembl chr  X:115,348,860...115,408,681
Ensembl chr11:115,348,860...115,408,681 		JBrowse link
G Il2 interleukin 2 acts_upstream_of
acts_upstream_of_or_within		 ISO UniProtKB:P22301 (PMID:22962438)
MGI:1857191 (PMID:1830926)		 RGD PMID:1830926 PMID:22962438 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il21 interleukin 21 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5450752|PMID:23045607)		 UniProt
RGD		 PMID:23045607 GO_REF:0000024 MGI:5450752 NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996 		JBrowse link
G Il33 interleukin 33 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P08226 (MGI:3775141|PMID:18268038)		 Ensembl
RGD		 PMID:18268038 GO_REF:0000107 MGI:3775141 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO MGI:1857195|MGI:96541 (PMID:15944273) RGD PMID:15944273 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO MGI:1861951 (PMID:15944273) RGD PMID:15944273 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980 		JBrowse link
G Il5 interleukin 5 involved_in ISO UniProtKB:Q8BVZ5 (MGI:3775141|PMID:18268038) RGD PMID:18268038 MGI:3775141 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Il6 interleukin 6 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5450752|PMID:23045607)
(PMID:3491322)		 UniProt
RGD		 PMID:3491322 PMID:23045607 GO_REF:0000024 MGI:5450752 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mzb1 marginal zone B and B1 cell-specific protein involved_in ISS
ISO		 GO_REF:0000024
(MGI:4366098|PMID:19805154), (MGI:4421284|PMID:19805157)		 UniProt
RGD		 PMID:19805154 PMID:19805157 GO_REF:0000024 MGI:4366098 MGI:4421284 NCBI chr18:27,238,999...27,241,060
Ensembl chr18:27,239,001...27,241,094 		JBrowse link
G Phb1 prohibitin 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5461234|PMID:23241883)		 UniProt
RGD		 PMID:23241883 GO_REF:0000024 MGI:5461234 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Phb2 prohibitin 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5461234|PMID:23241883)		 UniProt
Ensembl
RGD		 PMID:23241883 GO_REF:0000024 GO_REF:0000107 MGI:5461234 NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISO (PMID:1793833) RGD PMID:1793833 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Rbp4 retinol binding protein 4 involved_in ISO (MGI:3796317|PMID:10944490) RGD PMID:10944490 MGI:3796317 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:25631937) RGD PMID:25631937 NCBI chr20:4,870,939...4,910,183 JBrowse link
G Sash3 SAM and SH3 domain containing 3 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:3716944 (PMID:16227612)		 GO_Central
RGD		 PMID:16227612 GO_REF:0000033 NCBI chr  X:127,326,815...127,341,521
Ensembl chr  X:127,326,859...127,341,519 		JBrowse link
G Stx4 syntaxin 4 involved_in ISO (PMID:24055037) RGD PMID:24055037 NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO (PMID:23857366) RGD PMID:23857366 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 involved_in ISO (MGI:74350|PMID:7749983) RGD PMID:7749983 MGI:74350 NCBI chr 5:166,606,909...166,609,599
Ensembl chr 5:166,606,909...166,609,599 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:74350|PMID:7749983) RGD PMID:7749983 MGI:74350 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
G Vamp3 vesicle-associated membrane protein 3 NOT|involved_in ISO (PMID:24055037) RGD PMID:24055037 NCBI chr 5:161,498,109...161,508,704
Ensembl chr 5:161,498,109...161,508,751 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5605956|PMID:12612580)
(PMID:11460154)		 UniProt
Ensembl
RGD		 PMID:11460154 PMID:12612580 GO_REF:0000024 GO_REF:0000107 MGI:5605956 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
positive regulation of immunoglobulin production in mucosal tissue term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C10h17orf99 smilar to human chromosome 17 open reading frame 99 involved_in ISO (MGI:6103709|PMID:28978694) RGD PMID:28978694 MGI:6103709 NCBI chr10:103,015,371...103,027,407
Ensembl chr10:103,016,505...103,027,407 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5009207|PMID:9973465)		 Ensembl
RGD		 PMID:9973465 GO_REF:0000107 MGI:5009207 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3763508|PMID:12496423) RGD PMID:12496423 MGI:3763508 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exosc3 exosome component 3 acts_upstream_of_or_within ISO (PMID:21255825) RGD PMID:21255825 NCBI chr 5:59,573,849...59,579,065
Ensembl chr 5:59,573,886...59,579,060 		JBrowse link
G Exosc6 exosome component 6 acts_upstream_of_or_within ISO (PMID:21255825) RGD PMID:21255825 NCBI chr19:39,022,171...39,023,585
Ensembl chr19:39,022,183...39,023,515 		JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in ISS
ISO		 GO_REF:0000024
(MGI:6393148|PMID:31806351)		 UniProt
RGD		 PMID:31806351 GO_REF:0000024 MGI:6393148 NCBI chr 4:120,392,812...120,415,616
Ensembl chr 4:120,366,542...120,415,616 		JBrowse link
G Kmt5b lysine methyltransferase 5B involved_in ISS
ISO		 GO_REF:0000024
(MGI:6370097|PMID:28114273)		 UniProt
RGD		 PMID:28114273 GO_REF:0000024 MGI:6370097 NCBI chr 1:201,000,444...201,049,819
Ensembl chr 1:201,000,444...201,049,819 		JBrowse link
G Kmt5c lysine methyltransferase 5C involved_in ISO
ISS		 (MGI:6370097|PMID:28114273)
GO_REF:0000024		 RGD
UniProt		 PMID:28114273 GO_REF:0000024 MGI:6370097 NCBI chr 1:69,099,531...69,107,145
Ensembl chr 1:69,099,539...69,107,145 		JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 5:158,563,545...158,576,698
Ensembl chr 5:158,563,567...158,576,693 		JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (MGI:4821506|PMID:20671152) RGD PMID:20671152 MGI:4821506 NCBI chr 4:7,525,132...7,576,659
Ensembl chr 4:7,525,004...7,576,548 		JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (MGI:5468036|PMID:23306439), (MGI:5476381|PMID:23333305), (MGI:5490831|PMID:23333306) RGD PMID:23306439 PMID:23333305 PMID:23333306 MGI:5468036 MGI:5476381 MGI:5490831 NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617 		JBrowse link
G Shld1 shieldin complex subunit 1 involved_in ISO
IBA		 (PMID:29656893)
GO_REF:0000033		 RGD
GO_Central		 PMID:29656893 GO_REF:0000033 NCBI chr 3:119,938,695...120,011,068
Ensembl chr 3:119,938,833...120,009,550 		JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr16:9,544,940...9,640,323
Ensembl chr16:9,548,660...9,639,965 		JBrowse link
G Shld3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 2:35,297,255...35,302,071
Ensembl chr 2:35,295,859...35,302,346 		JBrowse link
G Tfrc transferrin receptor involved_in ISS
ISO		 GO_REF:0000024
(PMID:26642240)		 UniProt
RGD		 PMID:26642240 GO_REF:0000024 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in ISO (PMID:23345425), (PMID:23760478)
(MGI:3041657|PMID:15077110), (MGI:3046005|PMID:15159415)		 RGD PMID:15077110 PMID:15159415 PMID:23345425 PMID:23760478 MGI:3041657 MGI:3046005 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822 		JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:1342394|PMID:10430621)		 Ensembl
RGD		 PMID:10430621 GO_REF:0000107 MGI:1342394 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Msh2 mutS homolog 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:1342394|PMID:10430621)		 Ensembl
RGD		 PMID:10430621 GO_REF:0000107 MGI:1342394 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within ISO (PMID:23241889) RGD PMID:23241889 NCBI chr14:76,833,179...76,911,304
Ensembl chr14:76,835,637...76,913,641 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO UniProtKB:Q9JK91 (MGI:1342394|PMID:10430621) RGD PMID:10430621 MGI:1342394 NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:14988498)		 AgBase
RGD		 PMID:14988498 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnfsf13 TNF superfamily member 13 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:14988498)
MGI:3038886 (PMID:14988498)
GO_REF:0000033		 RGD
GO_Central		 PMID:14988498 GO_REF:0000033 NCBI chr10:54,400,054...54,403,723
Ensembl chr10:54,400,065...54,403,042 		JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcf1 cardiotrophin-like cytokine factor 1 involved_in ISO (MGI:3777853|PMID:12023368) RGD PMID:12023368 MGI:3777853 NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:14988498) RGD PMID:14988498 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within ISO MGI:107187 (PMID:10490661) RGD PMID:10490661 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495 		JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within ISO MGI:4127920 (PMID:25404367) RGD PMID:25404367 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845 		JBrowse link
G Cd28 Cd28 molecule acts_upstream_of_or_within ISO MGI:1857150 (PMID:7688139) RGD PMID:7688139 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685 		JBrowse link
G Cd40 CD40 molecule acts_upstream_of_or_within ISO (PMID:12882831) RGD PMID:12882831 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:12882831) RGD PMID:12882831 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO MGI:1857191 (PMID:1830926) RGD PMID:1830926 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:12882831), (PMID:14988498) RGD PMID:12882831 PMID:14988498 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Mlh1 mutL homolog 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:1342394|PMID:10430621)		 Ensembl
RGD		 PMID:10430621 GO_REF:0000107 MGI:1342394 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Msh2 mutS homolog 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:1342394|PMID:10430621)		 Ensembl
RGD		 PMID:10430621 GO_REF:0000107 MGI:1342394 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Pagr1 Paxip1-associated glutamate-rich protein 1 involved_in ISO (MGI:5752090|PMID:26744420) RGD PMID:26744420 MGI:5752090 NCBI chr 1:181,622,698...181,625,024 JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (MGI:5752090|PMID:26744420) RGD PMID:26744420 MGI:5752090 NCBI chr 4:7,525,132...7,576,659
Ensembl chr 4:7,525,004...7,576,548 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO UniProtKB:Q9JK91 (MGI:1342394|PMID:10430621) RGD PMID:10430621 MGI:1342394 NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:2181288 (PMID:9015183) RGD PMID:9015183 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Tbx21 T-box transcription factor 21 acts_upstream_of_or_within ISO MGI:2180194 (PMID:12882831) RGD PMID:12882831 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831 		JBrowse link
positive regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card9 caspase recruitment domain family, member 9 acts_upstream_of_or_within ISO MGI:3698412 (PMID:17187069) RGD PMID:17187069 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Casp1 caspase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:18490713)		 Ensembl
RGD		 PMID:18490713 GO_REF:0000107 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp4 caspase 4 acts_upstream_of_or_within ISO MGI:1931465|MGI:2653833 (PMID:22002608) RGD PMID:22002608 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Cd36 CD36 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2447190|MGI:3573941 (PMID:15690042), (PMID:16061696)		 Ensembl
RGD		 PMID:15690042 PMID:16061696 GO_REF:0000107 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd74 CD74 molecule involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(MGI:4943655|PMID:19413900)		 BHF-UCL
GO_Central
RGD		 PMID:19413900 GO_REF:0000024 GO_REF:0000033 MGI:4943655 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Gprc5b G protein-coupled receptor, class C, group 5, member B involved_in ISO (MGI:5545939|PMID:23169819) RGD PMID:23169819 MGI:5545939 NCBI chr 1:173,316,904...173,340,933
Ensembl chr 1:173,316,907...173,340,932 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:9348310) RGD PMID:9348310 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:6391873|PMID:22733818) RGD PMID:22733818 MGI:6391873 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 acts_upstream_of_or_within ISO (PMID:24020373) RGD PMID:24020373 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457 		JBrowse link
G Mir324 microRNA 324 acts_upstream_of_or_within ISO (PMID:24882011) RGD PMID:24882011 NCBI chr10:54,734,680...54,734,762
Ensembl chr10:54,734,678...54,734,766 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of_or_within ISO MGI:2147032|MGI:2385681 (PMID:10607756), (PMID:11067888), (PMID:12872135) RGD PMID:10607756 PMID:11067888 PMID:12872135 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of_or_within ISO MGI:2429397|MGI:2674231 (PMID:18261938) RGD PMID:18261938 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:1341839|MGI:2680581|MGI:3529594 (PMID:14560001), (PMID:15220916), (PMID:15692051), (PMID:18261938) RGD PMID:14560001 PMID:15220916 PMID:15692051 PMID:18261938 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:2386080|MGI:3606250 (PMID:11016935), (PMID:18490713) RGD PMID:11016935 PMID:18490713 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Panx1 Pannexin 1 acts_upstream_of_or_within ISO (PMID:18490713) RGD PMID:18490713 NCBI chr 8:11,851,176...11,889,774
Ensembl chr 8:11,850,730...11,889,774 		JBrowse link
G Plcg2 phospholipase C, gamma 2 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:5300086|PMID:22041900)
GO_REF:0000107		 RGD
Ensembl		 PMID:22041900 GO_REF:0000107 MGI:5300086 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Pycard PYD and CARD domain containing acts_upstream_of_or_within ISO MGI:107700|MGI:2653833 (PMID:22002608) RGD PMID:22002608 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO MGI:2660793 (PMID:11894098), (PMID:18261938) RGD PMID:11894098 PMID:18261938 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:19304799) RGD PMID:19304799 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
G Rtn4 reticulon 4 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4366092|PMID:19805174)		 UniProt
RGD		 PMID:19805174 GO_REF:0000024 MGI:4366092 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686 		JBrowse link
G Sema7a semaphorin 7A (John Milton Hagen blood group) involved_in ISO (MGI:3710037|PMID:17377534) RGD PMID:17377534 MGI:3710037 NCBI chr 8:58,348,448...58,370,536
Ensembl chr 8:58,348,448...58,370,536 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA		 (MGI:5319292|PMID:22315447)
GO_REF:0000107		 RGD
Ensembl		 PMID:22315447 GO_REF:0000107 MGI:5319292 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Spon2 spondin 2 acts_upstream_of_or_within ISO MGI:3026870 (PMID:14691481) RGD PMID:14691481 NCBI chr14:77,505,695...77,518,001
Ensembl chr14:77,511,901...77,517,996 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO MGI:108005|MGI:2679794|MGI:3029019 (PMID:12855817), (PMID:12872135) RGD PMID:12855817 PMID:12872135 NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Tirap TIR domain containing adaptor protein acts_upstream_of_or_within ISO MGI:3573942 (PMID:15690042) RGD PMID:15690042 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO MGI:2178675|MGI:2674036 (PMID:10549626), (PMID:11067888), (PMID:15690042), (PMID:18261938) RGD PMID:10549626 PMID:11067888 PMID:15690042 PMID:18261938 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr3 toll-like receptor 3 acts_upstream_of_or_within ISO MGI:3690535 (PMID:12855817), (PMID:18261938) RGD PMID:12855817 PMID:18261938 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857718|MGI:1860755|MGI:1860885 (PMID:10549626), (PMID:10607756), (PMID:10623794), (PMID:14691481), (PMID:15661922), (PMID:18261938), (PMID:21609717)		 Ensembl
RGD		 PMID:10549626 PMID:10607756 PMID:10623794 PMID:14691481 PMID:15661922 More... GO_REF:0000107 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr7 toll-like receptor 7 acts_upstream_of_or_within ISO (PMID:18261938) RGD PMID:18261938 NCBI chr  X:27,027,380...27,054,309
Ensembl chr  X:27,027,425...27,054,754 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO
IEA		 (PMID:18174455)
GO_REF:0000107		 RGD
Ensembl		 PMID:18174455 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
positive regulation of mast cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1a Fc epsilon receptor Ia acts_upstream_of_or_within ISO (PMID:9000133) RGD PMID:9000133 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351 		JBrowse link
G Fcer1g Fc epsilon receptor Ig acts_upstream_of_or_within ISO MGI:2384004 (PMID:14764707) RGD PMID:14764707 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO (PMID:20100931) RGD PMID:20100931 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5586645|PMID:24586680)		 UniProt
RGD		 PMID:24586680 GO_REF:0000024 MGI:5586645 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2384078 (PMID:9000133)		 Ensembl
RGD		 PMID:9000133 GO_REF:0000107 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
positive regulation of myeloid dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk4 calcium/calmodulin-dependent protein kinase IV NOT|involved_in ISO (PMID:17909078) RGD PMID:17909078 NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487 		JBrowse link
G Ddx1 DEAD-box helicase 1 involved_in ISO (MGI:5050760|PMID:21703541) RGD PMID:21703541 MGI:5050760 NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365 		JBrowse link
G Ddx21 DExD-box helicase 21 involved_in ISO (MGI:5050760|PMID:21703541) RGD PMID:21703541 MGI:5050760 NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543 		JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO (MGI:5050760|PMID:21703541) RGD PMID:21703541 MGI:5050760 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISS
ISO		 GO_REF:0000024
(MGI:5050760|PMID:21703541)		 UniProt
RGD		 PMID:21703541 GO_REF:0000024 MGI:5050760 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Rig1 RNA sensor RIG-1 involved_in ISO (MGI:5050760|PMID:21703541) RGD PMID:21703541 MGI:5050760 NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 involved_in ISO (MGI:5050760|PMID:21703541) RGD PMID:21703541 MGI:5050760 NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
positive regulation of myeloid leukocyte cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mif macrophage migration inhibitory factor involved_in ISO (MGI:2156302|PMID:11756671) RGD PMID:11756671 MGI:2156302 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
positive regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd160 CD160 molecule involved_in ISO (PMID:17307798) RGD PMID:17307798 NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834 		JBrowse link
G Cd226 CD226 molecule acts_upstream_of_or_within ISO MGI:4454325 (PMID:24658051) RGD PMID:24658051 NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051 		JBrowse link
G Clnk cytokine-dependent hematopoietic cell linker involved_in ISO (MGI:3774350|PMID:16439675) RGD PMID:16439675 MGI:3774350 NCBI chr14:71,923,894...72,101,180
Ensembl chr14:71,873,105...72,101,208 		JBrowse link
G Gimap5 GTPase, IMAP family member 5 IMP RGD PMID:15100275 RGD:2303778 NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086 		JBrowse link
G Il21 interleukin 21 acts_upstream_of_or_within ISO (PMID:14764669) RGD PMID:14764669 NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:30134159) RGD PMID:30134159 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:27455421) RGD PMID:27455421 NCBI chr20:3,403,418...3,479,476 JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:16366734), (PMID:19304799), (PMID:23184984) RGD PMID:16366734 PMID:19304799 PMID:23184984 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
positive regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2 microglobulin involved_in ISO
IEA		 (PMID:24643698)
GO_REF:0000107		 RGD
Ensembl		 PMID:24643698 GO_REF:0000107 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:16818763) RGD PMID:16818763 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831 		JBrowse link
G Cd7 Cd7 molecule involved_in ISO (PMID:10652336) RGD PMID:10652336 NCBI chr10:106,304,046...106,306,963
Ensembl chr10:106,304,056...106,306,967 		JBrowse link
G Fzd5 frizzled class receptor 5 involved_in ISO
IEA		 (PMID:16601243)
GO_REF:0000107		 RGD
Ensembl		 PMID:16601243 GO_REF:0000107 NCBI chr 9:66,113,096...66,120,276
Ensembl chr 9:66,113,112...66,121,457 		JBrowse link
G Malt1 MALT1 paracaspase involved_in ISO (PMID:15125833) RGD PMID:15125833 NCBI chr18:58,942,282...58,996,318
Ensembl chr18:58,942,299...58,994,260 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in ISO (PMID:15125833) RGD PMID:15125833 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G RT1-CE16 RT1 class I, locus CE16 involved_in ISO (PMID:24643698) RGD PMID:24643698 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
G Sash3 SAM and SH3 domain containing 3 acts_upstream_of_or_within ISO MGI:3716944 (PMID:16227612) RGD PMID:16227612 NCBI chr  X:127,326,815...127,341,521
Ensembl chr  X:127,326,859...127,341,519 		JBrowse link
G Sectm1b secreted and transmembrane 1B involved_in ISO (PMID:22184754) RGD PMID:22184754 NCBI chr10:106,324,070...106,333,779
Ensembl chr10:106,325,203...106,333,769 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4942267|PMID:9670042), (MGI:4943387|PMID:18354165) RGD PMID:9670042 PMID:18354165 MGI:4942267 MGI:4943387 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in ISO (PMID:15125833) RGD PMID:15125833 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO
IEA		 (PMID:15125833)
GO_REF:0000107		 RGD
Ensembl		 PMID:15125833 GO_REF:0000107 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (MGI:85636|PMID:9029087) RGD PMID:9029087 MGI:85636 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
positive regulation of T-helper 1 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid5a AT-rich interaction domain 5A involved_in ISO (MGI:5887181|PMID:27671645) RGD PMID:27671645 MGI:5887181 NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597 		JBrowse link
G Il18 interleukin 18 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:10653850)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:10653850 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il18r1 interleukin 18 receptor 1 involved_in ISO (PMID:10653850) RGD PMID:10653850 NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO
ISS		 (PMID:10653850)
GO_REF:0000024		 RGD
UniProt		 PMID:10653850 GO_REF:0000024 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 involved_in ISO
ISS		 (PMID:10653850)
GO_REF:0000024		 RGD
UniProt		 PMID:10653850 GO_REF:0000024 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937 		JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (MGI:5700493|PMID:9126961) RGD PMID:9126961 MGI:5700493 NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:1354779|PMID:10761931) RGD PMID:10761931 MGI:1354779 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5009207|PMID:9973465)		 Ensembl
RGD		 PMID:9973465 GO_REF:0000107 MGI:5009207 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
positive regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 Cd81 molecule involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:8766544)
(MGI:1926561|PMID:11046035)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:8766544 PMID:11046035 GO_REF:0000024 GO_REF:0000107 MGI:1926561 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660 		JBrowse link
G Dennd1b DENN domain containing 1B involved_in ISO (PMID:26774822)
(MGI:5751612|PMID:26774822)		 RGD PMID:26774822 MGI:5751612 NCBI chr13:50,545,324...50,772,922
Ensembl chr13:50,545,836...50,770,601 		JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO (PMID:15087456) RGD PMID:15087456 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Il4 interleukin 4 involved_in ISO (PMID:20554961) RGD PMID:20554961 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 involved_in ISO (MGI:5795829|PMID:11159963) RGD PMID:11159963 MGI:5795829 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in ISO (MGI:5689221|PMID:26098997) RGD PMID:26098997 MGI:5689221 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Prkcz protein kinase C, zeta involved_in ISS
ISO		 GO_REF:0000024
(MGI:3584076|PMID:15987782)		 UniProt
RGD		 PMID:15987782 GO_REF:0000024 MGI:3584076 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:3844206|PMID:19047684)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19047684 GO_REF:0000024 GO_REF:0000107 MGI:3844206 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5009207|PMID:9973465)		 Ensembl
RGD		 PMID:9973465 GO_REF:0000107 MGI:5009207 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Evpl envoplakin acts_upstream_of_or_within ISO MGI:1194898|MGI:96626 (PMID:27427436) RGD PMID:27427436 NCBI chr10:101,458,227...101,474,778
Ensembl chr10:101,458,216...101,474,763 		JBrowse link
G Ivl involucrin acts_upstream_of_or_within ISO MGI:107507|MGI:1194898 (PMID:27427436) RGD PMID:27427436 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100 		JBrowse link
G Ppl periplakin acts_upstream_of_or_within ISO MGI:107507|MGI:96626 (PMID:27427436) RGD PMID:27427436 NCBI chr10:10,450,919...10,496,575
Ensembl chr10:10,450,919...10,496,575 		JBrowse link
regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg5 autophagy related 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:22710871)		 Ensembl
RGD		 PMID:22710871 GO_REF:0000107 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Pkp3 plakophilin 3 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 1:196,187,914...196,198,843
Ensembl chr 1:196,187,835...196,198,844 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO UniProtKB:Q9Z0D9 (MGI:5888814|PMID:28052249) RGD PMID:28052249 MGI:5888814 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Tril TLR4 interactor with leucine-rich repeats involved_in ISO
IBA		 (PMID:19710467)
GO_REF:0000033		 RGD
GO_Central		 PMID:19710467 GO_REF:0000033 NCBI chr 4:82,922,327...82,927,172
Ensembl chr 4:82,922,328...82,927,172 		JBrowse link
regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO (PMID:19047410) RGD PMID:19047410 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr3 toll-like receptor 3 acts_upstream_of_or_within ISO (PMID:19047410) RGD PMID:19047410 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:19047410)		 Ensembl
RGD		 PMID:19047410 GO_REF:0000107 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr9 toll-like receptor 9 acts_upstream_of_or_within ISO (PMID:19047410) RGD PMID:19047410 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
regulation of immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40 CD40 molecule acts_upstream_of_or_within ISO (PMID:12958312) RGD PMID:12958312 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cd40lg CD40 ligand involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:12958312)		 Ensembl
RGD		 PMID:12958312 GO_REF:0000107 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Cgas cyclic GMP-AMP synthase acts_upstream_of_or_within ISO MGI:1328317 (PMID:26371324) RGD PMID:26371324 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO MGI:3696705 (PMID:16275384) RGD PMID:16275384 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Pkn1 protein kinase N1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:5475202 (PMID:23223530)		 Ensembl
RGD		 PMID:23223530 GO_REF:0000107 NCBI chr19:24,442,130...24,470,107
Ensembl chr19:24,442,122...24,470,107 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:12958312) RGD PMID:12958312 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 acts_upstream_of_or_within ISO (PMID:12958312) RGD PMID:12958312 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:12958312)		 Ensembl
RGD		 PMID:12958312 GO_REF:0000107 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:2442261 (PMID:26320659), (PMID:26371324) RGD PMID:26320659 PMID:26371324 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplf aprataxin and PNKP like factor acts_upstream_of_or_within ISO MGI:4128102 (PMID:21211721) RGD PMID:21211721 NCBI chr 4:120,070,471...120,122,656
Ensembl chr 4:120,070,471...120,122,633 		JBrowse link
G Mir181b1 microRNA 181b-1 acts_upstream_of_or_within ISO (PMID:18762567) RGD PMID:18762567 NCBI chr13:49,485,688...49,485,797
Ensembl chr13:49,485,688...49,485,797 		JBrowse link
G Mir181b2 microRNA 181b-2 acts_upstream_of_or_within ISO (PMID:18762567) RGD PMID:18762567 NCBI chr 3:22,616,948...22,617,035
Ensembl chr 3:22,616,948...22,617,035 		JBrowse link
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor involved_in ISO (MGI:5004983|PMID:21518874) RGD PMID:21518874 MGI:5004983 NCBI chr10:63,103,920...63,140,780
Ensembl chr10:63,103,921...63,140,780 		JBrowse link
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO MGI:3696705 (PMID:16275384) RGD PMID:16275384 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Il27ra interleukin 27 receptor subunit alpha acts_upstream_of_or_within ISO MGI:3525439 (PMID:11057672) RGD PMID:11057672 NCBI chr19:24,109,963...24,121,977
Ensembl chr19:24,109,972...24,121,938 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3695433 (PMID:17137798)		 Ensembl
RGD		 PMID:17137798 GO_REF:0000107 NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5649169|PMID:25310967)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:25310967 GO_REF:0000024 GO_REF:0000107 MGI:5649169 NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Litaf lipopolysaccharide-induced TNF factor acts_upstream_of_or_within ISO MGI:3687962 (PMID:16954198) RGD PMID:16954198 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763 		JBrowse link
G Ube2j1 ubiquitin-conjugating enzyme E2, J1 acts_upstream_of_or_within ISO MGI:109298 (PMID:24020373) RGD PMID:24020373 NCBI chr 5:47,422,476...47,441,476
Ensembl chr 5:47,422,587...47,441,461 		JBrowse link
regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calhm6 calcium homeostasis modulator family member 6 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:26,095,591...26,097,336
Ensembl chr20:26,095,592...26,097,278 		JBrowse link
regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl20 C-C motif chemokine ligand 20 NOT|involved_in ISO (MGI:3820359|PMID:19050256) RGD PMID:19050256 MGI:3820359 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5926947|PMID:28507030)		 UniProt
RGD		 PMID:28507030 GO_REF:0000024 MGI:5926947 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO
IBA		 (MGI:5888814|PMID:28052249)
GO_REF:0000033		 RGD
GO_Central		 PMID:28052249 GO_REF:0000033 MGI:5888814 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 involved_in ISO
IEA
ISS		 (PMID:20656926)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20656926 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532 		JBrowse link
somatic diversification of immunoglobulins term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase involved_in ISO (PMID:18722174) RGD PMID:18722174 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972 		JBrowse link
G Ctnnbl1 catenin, beta like 1 involved_in ISO
IEA		 (PMID:18722174)
GO_REF:0000107		 RGD
Ensembl		 PMID:18722174 GO_REF:0000107 NCBI chr 3:146,387,940...146,548,987
Ensembl chr 3:146,387,889...146,548,987 		JBrowse link
G Polb DNA polymerase beta acts_upstream_of_or_within ISO MGI:5427084 (PMID:24388753) RGD PMID:24388753 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812 		JBrowse link
somatic hypermutation of immunoglobulin genes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase involved_in ISO (PMID:21518874) RGD PMID:21518874 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972 		JBrowse link
G Exo1 exonuclease 1 acts_upstream_of_or_within ISO MGI:2653925 (PMID:14716311) RGD PMID:14716311 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654 		JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in ISS
ISO		 GO_REF:0000024
(MGI:7279208|PMID:35450882)
(PMID:35450882)		 UniProt
RGD		 PMID:35450882 GO_REF:0000024 MGI:7279208 NCBI chr 4:120,392,812...120,415,616
Ensembl chr 4:120,366,542...120,415,616 		JBrowse link
G Mcm3ap minichromosome maintenance complex component 3 associated protein involved_in ISO (PMID:23652018) RGD PMID:23652018 NCBI chr20:12,127,570...12,165,165
Ensembl chr20:12,127,570...12,165,165 		JBrowse link
G Mlh1 mutL homolog 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:1857946 (PMID:10092760), (PMID:10429667)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:10092760 PMID:10429667 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Msh2 mutS homolog 2 involved_in
NOT|acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1858055 (PMID:9607915)
MGI:109352|MGI:1857940|MGI:1858055|MGI:2680817 (PMID:14568978), (PMID:15494304), (PMID:9607916), (PMID:9697842), (PMID:9697843)		 Ensembl
RGD		 PMID:9607915 PMID:9607916 PMID:9697842 PMID:9697843 PMID:14568978 More... GO_REF:0000107 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Msh3 mutS homolog 3 NOT|acts_upstream_of_or_within ISO MGI:1858056 (PMID:10662804) RGD PMID:10662804 NCBI chr 2:23,444,326...23,585,777 JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within ISO MGI:1858014|MGI:3653701 (PMID:10662804), (PMID:15238604), (PMID:16618598), (PMID:17015724) RGD PMID:10662804 PMID:15238604 PMID:16618598 PMID:17015724 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956 		JBrowse link
G Nuggc nuclear GTPase, germinal center associated acts_upstream_of_or_within ISO MGI:5449552 (PMID:22833677) RGD PMID:22833677 NCBI chr15:39,821,851...39,866,122
Ensembl chr15:39,821,855...39,866,122 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in
acts_upstream_of_or_within		 ISO
IBA		 (MGI:1261707|PMID:9618520)
MGI:1857947 (PMID:10429667)
GO_REF:0000033		 RGD
GO_Central		 PMID:9618520 PMID:10429667 GO_REF:0000033 MGI:1261707 NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066 		JBrowse link
G Polb DNA polymerase beta acts_upstream_of_or_within ISO MGI:5427084 (PMID:24388753) RGD PMID:24388753 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812 		JBrowse link
G Polm DNA polymerase mu acts_upstream_of_or_within ISO MGI:2179233 (PMID:15789338) RGD PMID:15789338 NCBI chr14:80,707,075...80,716,677
Ensembl chr14:80,706,345...80,717,086 		JBrowse link
G Polq DNA polymerase theta involved_in ISO (MGI:3603978|PMID:16172387), (MGI:3609287|PMID:16222339), (MGI:3692678|PMID:16890500) RGD PMID:16172387 PMID:16222339 PMID:16890500 MGI:3603978 MGI:3609287 MGI:3692678 NCBI chr11:63,673,796...63,775,905
Ensembl chr11:63,673,816...63,775,878 		JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in ISO (MGI:6157199|PMID:29669924) RGD PMID:29669924 MGI:6157199 NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386 		JBrowse link
G Ung uracil-DNA glycosylase acts_upstream_of_or_within ISO MGI:101816|MGI:2182610 (PMID:15494304), (PMID:17015724) RGD PMID:15494304 PMID:17015724 NCBI chr12:42,485,276...42,494,217
Ensembl chr12:42,485,276...42,494,206 		JBrowse link
somatic recombination of immunoglobulin gene segments term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 acts_upstream_of_or_within ISO MGI:1857946 (PMID:11828012) RGD PMID:11828012 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Msh2 mutS homolog 2 acts_upstream_of_or_within ISO MGI:109352|MGI:1857940|MGI:2151801|MGI:2680817 (PMID:11828012), (PMID:14563316), (PMID:14568978), (PMID:15494304), (PMID:15955838) RGD PMID:11828012 PMID:14563316 PMID:14568978 PMID:15494304 PMID:15955838 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Msh3 mutS homolog 3 acts_upstream_of_or_within ISO MGI:1858056 (PMID:15238604) RGD PMID:15238604 NCBI chr 2:23,444,326...23,585,777 JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within ISO MGI:1858014 (PMID:15238604) RGD PMID:15238604 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component acts_upstream_of_or_within ISO MGI:1857947 (PMID:11828012) RGD PMID:11828012 NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066 		JBrowse link
G Ung uracil-DNA glycosylase acts_upstream_of_or_within ISO MGI:101816|MGI:2182610 (PMID:15494304) RGD PMID:15494304 NCBI chr12:42,485,276...42,494,217
Ensembl chr12:42,485,276...42,494,206 		JBrowse link
somatic recombination of immunoglobulin genes involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 acts_upstream_of_or_within ISO MGI:101816 (PMID:12743174) RGD PMID:12743174 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Msh2 mutS homolog 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:101938 (PMID:12743174)		 GO_Central
RGD		 PMID:12743174 GO_REF:0000033 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    immune system process 2853
      production of molecular mediator of immune response 247
        antimicrobial peptide production + 14
        cytokine production involved in immune response + 134
        granulysin production 0
        granzyme A production + 1
        granzyme B production + 3
        immunoglobulin production + 116
        negative regulation of production of molecular mediator of immune response + 47
        perforin production 0
        positive regulation of production of molecular mediator of immune response + 151
        regulation of production of molecular mediator of immune response + 213
Path 2
Term Annotations click to browse term
  biological_process 20115
    metabolic process 12289
      biosynthetic process 8418
        cellular biosynthetic process 7985
          macromolecule biosynthetic process 7442
            gene expression 6970
              production of molecular mediator of immune response 247
                antimicrobial peptide production + 14
                cytokine production involved in immune response + 134
                granulysin production 0
                granzyme A production + 1
                granzyme B production + 3
                immunoglobulin production + 116
                negative regulation of production of molecular mediator of immune response + 47
                perforin production 0
                positive regulation of production of molecular mediator of immune response + 151
                regulation of production of molecular mediator of immune response + 213
paths to the root