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ONTOLOGY REPORT - ANNOTATIONS


Term:production of molecular mediator of immune response
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Accession:GO:0002440 term browser browse the term
Definition:The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels.
Comment:Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
Synonyms:related_synonym: production of cellular mediator of immune response


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antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp7 matrix metallopeptidase 7 ISO (MGI:4838964|PMID:20056603) RGD PMID:20056603 MGI:4838964 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
antibacterial peptide secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp7 matrix metallopeptidase 7 ISO (MGI:3698376|PMID:11248802) RGD PMID:11248802 MGI:3698376 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
B cell affinity maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase ISO MGI:1856317 (MGI:65977|PMID:7680896) RGD PMID:7680896 MGI:65977 NCBI chr  X:105,360,922...105,390,580
Ensembl chr  X:105,360,922...105,390,580
JBrowse link
G RT1-Bb RT1 class II, locus Bb IEA
ISO
GO_REF:0000107
(MGI:4943414|PMID:1378867)
Ensembl
RGD
PMID:1378867 GO_REF:0000107, MGI:4943414 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711
JBrowse link
biosynthetic process of antibacterial peptides active against Gram-negative bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elane elastase, neutrophil expressed ISO (PMID:20421939) RGD PMID:20421939 NCBI chr 7:12,638,320...12,640,168
Ensembl chr 7:12,638,322...12,640,232
JBrowse link
cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO (PMID:20441518) RGD PMID:20441518 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Tlr2 toll-like receptor 2 ISO (PMID:20441518) RGD PMID:20441518 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Trem3 triggering receptor expressed on myeloid cells 3 IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 9:14,713,935...14,725,945
Ensembl chr 9:14,713,935...14,724,093
JBrowse link
immunoglobulin heavy chain V-D-J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Polb DNA polymerase beta ISO MGI:5427084 (MGI:5553198|PMID:24388753) RGD PMID:24388753 MGI:5553198 NCBI chr16:74,237,001...74,260,272
Ensembl chr16:74,237,001...74,260,271
JBrowse link
G Yy1 YY1 transcription factor ISO MGI:3624790 (MGI:5484711|PMID:23531880) RGD PMID:23531880 MGI:5484711 NCBI chr 6:132,702,443...132,726,848
Ensembl chr 6:132,702,448...132,727,046
JBrowse link
immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40lg CD40 ligand IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Galnt2 polypeptide N-acetylgalactosaminyltransferase 2 ISO (PMID:12438318) RGD PMID:12438318 NCBI chr19:57,043,858...57,115,123
Ensembl chr19:57,047,830...57,115,132
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit IMP RGD PMID:22981234 RGD:8696027 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C ISO (PMID:1793833) RGD PMID:1793833 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
immunoglobulin V(D)J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 ISO MGI:3711150 (MGI:3662963|PMID:16819554) RGD PMID:16819554 MGI:3662963 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755
JBrowse link
G Lig4 DNA ligase 4 IBA
ISO
PMID:21873635
MGI:1857732 (MGI:1312981|PMID:9823897)
RGD PMID:9823897, PMID:21873635 MGI:1312981, RGD:13792537 NCBI chr16:85,331,771...85,339,496
Ensembl chr16:85,331,866...85,337,769
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit IBA
ISO
PMID:21873635
MGI:2383951 (MGI:1290043|PMID:9768755)
RGD PMID:9768755, PMID:21873635 MGI:1290043, RGD:13792537 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link
G Tcf3 transcription factor 3 ISO
IBA
IEA
(PMID:16428437)
MGI:2178112 (MGI:3615721|PMID:16428437)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:16428437, PMID:21873635 GO_REF:0000107, MGI:3615721, RGD:13792537 NCBI chr 7:12,146,642...12,168,400
Ensembl chr 7:12,144,162...12,168,410
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 IBA
ISO
PMID:21873635
MGI:1926771 (MGI:1913213|PMID:9875844)
RGD PMID:9875844, PMID:21873635 MGI:1913213, RGD:13792537 NCBI chr 2:18,674,496...18,927,463
Ensembl chr 2:18,677,220...18,927,365
JBrowse link
isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase ISO (MGI:3761960|PMID:17713479), (MGI:5004983|PMID:21518874) RGD PMID:17713479, PMID:21518874 MGI:3761960, MGI:5004983 NCBI chr 4:155,359,909...155,371,104
Ensembl chr 4:155,359,921...155,369,671
JBrowse link
G Atad5 ATPase family, AAA domain containing 5 ISO MGI:4127920 (MGI:5763555|PMID:25404367) RGD PMID:25404367 MGI:5763555 NCBI chr10:67,427,042...67,475,825
Ensembl chr10:67,427,066...67,473,649
JBrowse link
G Batf basic leucine zipper ATF-like transcription factor ISS
ISO
GO_REF:0000024
(MGI:4456325|PMID:20421391), (MGI:5004732|PMID:21572431)
UniProt
RGD
PMID:20421391, PMID:21572431 GO_REF:0000024, MGI:4456325, MGI:5004732 NCBI chr 6:109,562,415...109,584,541
Ensembl chr 6:109,562,587...109,584,545
JBrowse link
G Cd40lg CD40 ligand IEA
ISO
GO_REF:0000107
(MGI:3687427|PMID:7529792)
Ensembl
RGD
PMID:7529792 GO_REF:0000107, MGI:3687427 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit ISO MGI:2183944 (MGI:3052883|PMID:15280420) RGD PMID:15280420 MGI:3052883 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Exo1 exonuclease 1 ISO MGI:2653925 (MGI:3028407|PMID:14716311) RGD PMID:14716311 MGI:3028407 NCBI chr13:93,936,989...93,962,749
Ensembl chr13:93,939,022...93,960,342
JBrowse link
G Exosc3 exosome component 3 ISO (MGI:5009766|PMID:21255825) RGD PMID:21255825 MGI:5009766 NCBI chr 5:60,866,498...60,871,734
Ensembl chr 5:60,868,502...60,871,705
JBrowse link
G Exosc6 exosome component 6 ISO (MGI:5009766|PMID:21255825) RGD PMID:21255825 MGI:5009766 NCBI chr19:43,190,879...43,193,164
Ensembl chr19:43,191,390...43,192,208
JBrowse link
G Lig4 DNA ligase 4 ISO MGI:1857732 (MGI:3761960|PMID:17713479) RGD PMID:17713479 MGI:3761960 NCBI chr16:85,331,771...85,339,496
Ensembl chr16:85,331,866...85,337,769
JBrowse link
G Mlh1 mutL homolog 1 IEA
ISO
GO_REF:0000107
MGI:1857946 (MGI:2662086|PMID:12743174)
Ensembl
RGD
PMID:12743174 GO_REF:0000107, MGI:2662086 NCBI chr 8:119,486,655...119,523,716
Ensembl chr 8:119,486,691...119,523,964
JBrowse link
G Msh2 mutS homolog 2 IEA
ISO
GO_REF:0000107
MGI:1857940|MGI:2151801 (MGI:1342394|PMID:10430621), (MGI:2662086|PMID:12743174)
Ensembl
RGD
PMID:10430621, PMID:12743174 GO_REF:0000107, MGI:1342394, MGI:2662086 NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932
JBrowse link
G Msh6 mutS homolog 6 ISO MGI:109352|MGI:3653701 (MGI:3641510|PMID:16618598), (MGI:3723381|PMID:17015724) RGD PMID:16618598, PMID:17015724 MGI:3641510, MGI:3723381 NCBI chr 6:11,644,565...11,662,389
Ensembl chr 6:11,644,578...11,662,499
JBrowse link
G Nbn nibrin IEA
ISO
ISS
GO_REF:0000107
(MGI:3529405|PMID:15668383)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:15668383 GO_REF:0000024, GO_REF:0000107, MGI:3529405 NCBI chr 5:29,622,347...29,656,877
Ensembl chr 5:29,622,281...29,656,864
JBrowse link
G Rnf168 ring finger protein 168 ISS
ISO
GO_REF:0000024
(MGI:4420833|PMID:20080757)
UniProt
RGD
PMID:20080757 GO_REF:0000024, MGI:4420833 NCBI chr11:71,721,242...71,743,421
Ensembl chr11:71,721,250...71,743,421
JBrowse link
G Rnf8 ring finger protein 8 ISS
ISO
GO_REF:0000024
(MGI:4420833|PMID:20080757)
UniProt
RGD
PMID:20080757 GO_REF:0000024, MGI:4420833 NCBI chr20:8,285,380...8,309,858
Ensembl chr20:8,285,296...8,309,908
JBrowse link
G Swap70 switching B-cell complex subunit SWAP70 ISO (MGI:1270060|PMID:9642267) RGD PMID:9642267 MGI:1270060 NCBI chr 1:174,862,683...174,924,101
Ensembl chr 1:174,862,698...174,924,078
JBrowse link
G Ung uracil-DNA glycosylase ISO MGI:1343961 (MGI:3723381|PMID:17015724) RGD PMID:17015724 MGI:3723381 NCBI chr12:48,246,593...48,255,547
Ensembl chr12:48,246,569...48,254,822
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 ISO MGI:1926771|MGI:3047571|MGI:3641440 (MGI:3761960|PMID:17713479) RGD PMID:17713479 MGI:3761960 NCBI chr 2:18,674,496...18,927,463
Ensembl chr 2:18,677,220...18,927,365
JBrowse link
isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr6 C-C motif chemokine receptor 6 ISO (MGI:5787846|PMID:27174992) RGD PMID:27174992 MGI:5787846 NCBI chr 1:53,063,380...53,087,519
Ensembl chr 1:53,065,025...53,087,474
JBrowse link
isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspd1 heat shock protein family D (Hsp60) member 1 ISO (PMID:16148103) RGD PMID:16148103 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
negative regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spink5 serine peptidase inhibitor, Kazal type 5 ISO (MGI:3770082|PMID:17012259) RGD PMID:17012259 MGI:3770082 NCBI chr18:35,118,300...35,190,458
Ensembl chr18:35,121,967...35,191,069
Ensembl chr 1:35,121,967...35,191,069
JBrowse link
negative regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 IEA
ISO
GO_REF:0000107
(MGI:4437182|PMID:20060382)
Ensembl
RGD
PMID:20060382 GO_REF:0000107, MGI:4437182 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
JBrowse link
G Apoa1 apolipoprotein A1 ISO (PMID:12458630) RGD PMID:12458630 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoa2 apolipoprotein A2 ISO (PMID:12458630) RGD PMID:12458630 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
JBrowse link
G Il10 interleukin 10 ISO
ISS
(PMID:10443688)
GO_REF:0000024
RGD
UniProt
PMID:10443688 GO_REF:0000024 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Tnf tumor necrosis factor ISO (PMID:10443688) RGD PMID:10443688 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
negative regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jak3 Janus kinase 3 ISS
ISO
GO_REF:0000024
(MGI:3719947|PMID:16020505)
BHF-UCL
RGD
PMID:16020505 GO_REF:0000024, MGI:3719947 NCBI chr16:20,107,471...20,120,678
Ensembl chr16:20,109,200...20,120,668
JBrowse link
negative regulation of immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd22 CD22 molecule ISO UniProtKB:Q80ZE3 (MGI:4453395|PMID:20200274) RGD PMID:20200274 MGI:4453395 NCBI chr 1:89,313,475...89,329,902
Ensembl chr 1:89,314,558...89,329,418
JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb ISO MGI:1857166 (MGI:3608295|PMID:12385742) RGD PMID:12385742 MGI:3608295 NCBI chr13:89,329,298...89,343,916
Ensembl chr13:89,327,794...89,433,815
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 IEA
ISO
GO_REF:0000107
MGI:2653910 (MGI:3589858|PMID:15944273)
Ensembl
RGD
PMID:15944273 GO_REF:0000107, MGI:3589858 NCBI chr  X:118,443,955...118,514,716
Ensembl chr  X:118,443,823...118,513,061
JBrowse link
G Il33 interleukin 33 IEA
ISO
GO_REF:0000107
UniProtKB:P08226 (MGI:3775141|PMID:18268038)
Ensembl
RGD
PMID:18268038 GO_REF:0000107, MGI:3775141 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit IMP RGD PMID:22981234 RGD:8696027 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link
G Siglec10 sialic acid binding Ig-like lectin 10 ISO UniProtKB:P35329 (MGI:4453395|PMID:20200274) RGD PMID:20200274 MGI:4453395 NCBI chr 1:98,512,663...98,521,736
Ensembl chr 1:98,512,625...98,521,706
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 ISO (MGI:3840374|PMID:19328063) RGD PMID:19328063 MGI:3840374 NCBI chr 7:141,039,433...141,070,269
Ensembl chr 7:141,034,982...141,069,989
JBrowse link
G Zpbp2 zona pellucida binding protein 2 ISO MGI:3762590 (MGI:6150730|PMID:29536159) RGD PMID:29536159 MGI:6150730 NCBI chr10:86,513,645...86,523,375
Ensembl chr10:86,514,830...86,523,372
JBrowse link
negative regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp3 poly (ADP-ribose) polymerase family, member 3 ISO (MGI:6214451|PMID:26000965) RGD PMID:26000965 MGI:6214451 NCBI chr 8:115,173,440...115,179,543
Ensembl chr 8:115,173,453...115,179,191
JBrowse link
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Da2-19 uncharacterized LOC302729 ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:48,196,789...48,213,506
Ensembl chr  X:48,196,916...48,213,505
JBrowse link
G Thoc1 THO complex 1 ISO (MGI:5520039|PMID:22144908) RGD PMID:22144908 MGI:5520039 NCBI chr18:1,142,540...1,177,084
Ensembl chr18:1,142,782...1,176,974
JBrowse link
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor ISO MGI:103034|MGI:2158438 (MGI:1345885|PMID:10490661) RGD PMID:10490661 MGI:1345885 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Foxp3 forkhead box P3 ISO MGI:3696705 (MGI:3695768|PMID:16275384) RGD PMID:16275384 MGI:3695768 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 ISO MGI:3695433 (MGI:3694584|PMID:17137798) RGD PMID:17137798 MGI:3694584 NCBI chr18:31,574,759...31,625,286
Ensembl chr18:31,574,821...31,625,274
JBrowse link
negative regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cuedc2 CUE domain containing 2 ISO (PMID:24882011)
MGI:5635142 (MGI:5576401|PMID:24882011)
RGD PMID:24882011 MGI:5576401 NCBI chr 1:266,078,107...266,087,057
Ensembl chr 1:266,078,108...266,086,299
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 ISO (MGI:2183694|PMID:12150927) RGD PMID:12150927 MGI:2183694 NCBI chr 7:64,922,830...64,982,224
Ensembl chr 7:64,923,615...64,982,281
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO
ISS
(PMID:20875417)
GO_REF:0000024
RGD
AgBase
PMID:20875417 GO_REF:0000024 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO
ISS
(PMID:20875417)
GO_REF:0000024
RGD
AgBase
PMID:20875417 GO_REF:0000024 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgfb3 transforming growth factor, beta 3 ISO
ISS
(PMID:20875417)
GO_REF:0000024
RGD
AgBase
PMID:20875417 GO_REF:0000024 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
negative regulation of mast cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor ISO MGI:2158436 (MGI:3581006|PMID:15950739) RGD PMID:15950739 MGI:3581006 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:17234154 RGD:1601626 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
negative regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd96 CD96 molecule ISO MGI:5617136 (MGI:5569209|PMID:24658051) RGD PMID:24658051 MGI:5569209 NCBI chr11:57,108,757...57,183,855
Ensembl chr11:57,108,956...57,183,270
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991
JBrowse link
negative regulation of plasmacytoid dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bst2 bone marrow stromal cell antigen 2 ISO
ISS
(PMID:19564354)
GO_REF:0000024
RGD
UniProt
PMID:19564354 GO_REF:0000024 NCBI chr16:19,938,781...19,942,353
Ensembl chr16:19,938,784...19,942,353
JBrowse link
negative regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 ISO (PMID:15466453), (PMID:23169781) RGD PMID:15466453, PMID:23169781 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Hfe homeostatic iron regulator ISO UniProtKB:P04439 (PMID:24643698) RGD PMID:24643698 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 ISO (PMID:18420485) RGD PMID:18420485 NCBI chr 1:73,393,854...73,399,448
Ensembl chr 1:73,393,850...73,399,579
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991
JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 ISO (MGI:5700313|PMID:11477403) RGD PMID:11477403 MGI:5700313 NCBI chr13:90,184,545...90,219,170
Ensembl chr13:90,184,569...90,219,217
JBrowse link
G Smad7 SMAD family member 7 IEA
ISO
GO_REF:0000107
(MGI:5634593|PMID:25642768)
Ensembl
RGD
PMID:25642768 GO_REF:0000107, MGI:5634593 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157
JBrowse link
G Vsir V-set immunoregulatory receptor ISO (MGI:5292805|PMID:21383057) RGD PMID:21383057 MGI:5292805 NCBI chr20:29,897,543...29,923,381
Ensembl chr20:29,897,594...29,919,998
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 ISO (PMID:10887101) RGD PMID:10887101 NCBI chr13:83,199,402...83,202,845
Ensembl chr13:83,199,264...83,202,864
JBrowse link
negative regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 ISO (MGI:5908339|PMID:19360123) RGD PMID:19360123 MGI:5908339 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Ifnb1 interferon beta 1 ISO (PMID:20554961) RGD PMID:20554961 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Tbx21 T-box transcription factor 21 ISO (MGI:5543347|PMID:23616576) RGD PMID:23616576 MGI:5543347 NCBI chr10:85,032,799...85,049,331
Ensembl chr10:85,032,799...85,049,331
JBrowse link
positive regulation of antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO (MGI:3775881|PMID:18167348) RGD PMID:18167348 MGI:3775881 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
positive regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klk5 kallikrein related-peptidase 5 ISO
IBA
(PMID:17012259)
PMID:21873635
RGD PMID:17012259, PMID:21873635 RGD:13792537 NCBI chr 1:99,781,291...99,793,745
Ensembl chr 1:99,781,237...99,786,330
JBrowse link
G Klk7 kallikrein-related peptidase 7 ISO
IEA
(PMID:17012259)
GO_REF:0000107
RGD
Ensembl
PMID:17012259 GO_REF:0000107 NCBI chr 1:99,749,991...99,754,723
Ensembl chr 1:99,749,936...99,754,435
JBrowse link
G Pgc progastricsin ISO (PMID:12759353) RGD PMID:12759353 NCBI chr 9:15,266,699...15,274,917
Ensembl chr 9:15,266,699...15,274,917
JBrowse link
positive regulation of antimicrobial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il17a interleukin 17A IEA
ISO
GO_REF:0000107
(MGI:3828868|PMID:19144317)
Ensembl
RGD
PMID:19144317 GO_REF:0000107, MGI:3828868 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il17f interleukin 17F IEA
ISO
GO_REF:0000107
(MGI:3828868|PMID:19144317)
Ensembl
RGD
PMID:19144317 GO_REF:0000107, MGI:3828868 NCBI chr 9:26,885,702...26,897,219
Ensembl chr 9:26,885,708...26,897,219
JBrowse link
positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO MGI:3529594 (MGI:3528786|PMID:15692051) RGD PMID:15692051 MGI:3528786 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
positive regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Defb43 defensin beta 43 ISO (PMID:26649771) RGD PMID:26649771 NCBI chr15:46,196,771...46,201,271
Ensembl chr15:46,196,771...46,201,271
JBrowse link
G F2rl1 F2R like trypsin receptor 1 ISO
ISS
(PMID:11441110)
GO_REF:0000024
RGD
UniProt
PMID:11441110 GO_REF:0000024 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G Ffar2 free fatty acid receptor 2 ISS
ISO
GO_REF:0000024
(MGI:5575446|PMID:23665276)
UniProt
RGD
PMID:23665276 GO_REF:0000024, MGI:5575446 NCBI chr 1:89,268,197...89,271,942
Ensembl chr 1:89,268,938...89,269,930
JBrowse link
G Ffar3 free fatty acid receptor 3 ISS
ISO
GO_REF:0000024
(MGI:5575446|PMID:23665276)
UniProt
RGD
PMID:23665276 GO_REF:0000024, MGI:5575446 NCBI chr 1:89,302,035...89,304,064
Ensembl chr 1:89,302,039...89,303,968
JBrowse link
G Hk1 hexokinase 1 IEA
ISO
GO_REF:0000107
(MGI:5790524|PMID:27374331)
Ensembl
RGD
PMID:27374331 GO_REF:0000107, MGI:5790524 NCBI chr20:31,911,460...31,979,780
Ensembl chr20:31,912,262...31,956,649
JBrowse link
G Kars lysyl-tRNA synthetase ISO (PMID:15851690) RGD PMID:15851690 NCBI chr19:44,212,205...44,231,209
Ensembl chr19:44,212,206...44,231,157
JBrowse link
G Mapk14 mitogen activated protein kinase 14 IEA
ISO
GO_REF:0000107
(MGI:5882898|PMID:15851690)
Ensembl
RGD
PMID:15851690 GO_REF:0000107, MGI:5882898 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 ISO (MGI:5882898|PMID:15851690) RGD PMID:15851690 MGI:5882898 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Tek TEK receptor tyrosine kinase ISO (MGI:4437182|PMID:20060382) RGD PMID:20060382 MGI:4437182 NCBI chr 5:113,725,717...113,852,799
Ensembl chr 5:113,725,717...113,852,799
JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 IBA
ISO
PMID:21873635
MGI:4940320 (MGI:4881849|PMID:21236258)
RGD PMID:21236258, PMID:21873635 MGI:4881849, RGD:13792537 NCBI chr 5:172,328,259...172,337,221
Ensembl chr 5:172,328,262...172,335,892
JBrowse link
G Trim6 tripartite motif containing 6 ISO (PMID:24882218) RGD PMID:24882218 NCBI chr 1:169,410,084...169,423,305
Ensembl chr 1:169,410,115...169,423,283
JBrowse link
G Wnt5a Wnt family member 5A ISO (PMID:18174455) RGD PMID:18174455 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
positive regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide-binding oligomerization domain containing 2 IDA RGD PMID:16818757 RGD:1600784 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein ISO (MGI:5803730|PMID:27288407) RGD PMID:27288407 MGI:5803730 NCBI chr10:57,415,429...57,436,412
Ensembl chr10:57,415,832...57,436,368
JBrowse link
positive regulation of granzyme A production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Xcl1 X-C motif chemokine ligand 1 ISO (PMID:18832695) RGD PMID:18832695 NCBI chr13:83,199,402...83,202,845
Ensembl chr13:83,199,264...83,202,864
JBrowse link
positive regulation of granzyme B production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd244 CD244 molecule ISO (PMID:11714776) RGD PMID:11714776 NCBI chr13:89,959,091...89,995,993
Ensembl chr13:89,975,267...89,995,974
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 IBA
ISO
PMID:21873635
(MGI:5562517|PMID:23871208)
RGD PMID:23871208, PMID:21873635 MGI:5562517, RGD:13792537 NCBI chr 2:206,342,066...206,390,348
Ensembl chr 2:206,342,066...206,390,348
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 ISO (PMID:18832695) RGD PMID:18832695 NCBI chr13:83,199,402...83,202,845
Ensembl chr13:83,199,264...83,202,864
JBrowse link
positive regulation of immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd37 CD37 molecule ISO MGI:2386160 (MGI:1860745|PMID:10891477) RGD PMID:10891477 MGI:1860745 NCBI chr 1:101,230,470...101,236,061
Ensembl chr 1:101,230,533...101,236,065
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 ISO MGI:3053071|MGI:5609428 (MGI:5451119|PMID:23123061) RGD PMID:23123061 MGI:5451119 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 ISO (MGI:3777853|PMID:12023368) RGD PMID:12023368 MGI:3777853 NCBI chr 1:219,468,866...219,472,445
Ensembl chr 1:219,468,675...219,472,654
JBrowse link
G Foxp1 forkhead box P1 ISO MGI:3711150 (MGI:3662963|PMID:16819554) RGD PMID:16819554 MGI:3662963 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755
JBrowse link
G Gpi glucose-6-phosphate isomerase ISO (PMID:3020690) RGD PMID:3020690 NCBI chr 1:90,063,411...90,091,287
Ensembl chr 1:90,063,411...90,091,287
JBrowse link
G Hpx hemopexin ISO MGI:2447193 (MGI:3807609|PMID:18641331) RGD PMID:18641331 MGI:3807609 NCBI chr 1:170,423,558...170,431,066
Ensembl chr 1:170,423,483...170,431,073
JBrowse link
G Il10 interleukin 10 ISO UniProtKB:P60568 (PMID:22962438) RGD PMID:22962438 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il13 interleukin 13 IDA
ISO
IgE production after infection
MGI:1931804|MGI:96556 (MGI:3589858|PMID:15944273)
RGD PMID:15944273, PMID:11573960 MGI:3589858, RGD:633067 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 IDA IgE production after infection RGD PMID:11573960 RGD:633067 NCBI chr  X:122,724,081...122,783,801
Ensembl chr  X:122,724,129...122,781,479
JBrowse link
G Il2 interleukin 2 ISO UniProtKB:P22301 (PMID:22962438)
MGI:1857191 (MGI:87443|PMID:1830926)
RGD PMID:1830926, PMID:22962438 MGI:87443 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il33 interleukin 33 IEA
ISO
GO_REF:0000107
UniProtKB:P08226 (MGI:3775141|PMID:18268038)
Ensembl
RGD
PMID:18268038 GO_REF:0000107, MGI:3775141 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Il4 interleukin 4 ISO MGI:1857195|MGI:96541 (MGI:3589858|PMID:15944273) RGD PMID:15944273 MGI:3589858 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il4r interleukin 4 receptor ISO MGI:1861951 (MGI:3589858|PMID:15944273) RGD PMID:15944273 MGI:3589858 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Il5 interleukin 5 ISO UniProtKB:Q8BVZ5 (MGI:3775141|PMID:18268038) RGD PMID:18268038 MGI:3775141 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 ISO (PMID:3491322) RGD PMID:3491322 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mzb1 marginal zone B and B1 cell-specific protein ISS
ISO
IBA
GO_REF:0000024
(MGI:4366098|PMID:19805154), (MGI:4421284|PMID:19805157)
PMID:21873635
UniProt
RGD
PMID:19805154, PMID:19805157, PMID:21873635 GO_REF:0000024, MGI:4366098, MGI:4421284, RGD:13792537 NCBI chr18:28,436,546...28,438,607
Ensembl chr18:28,436,548...28,438,654
JBrowse link
G Rbp4 retinol binding protein 4 ISO (MGI:3796317|PMID:10944490) RGD PMID:10944490 MGI:3796317 NCBI chr 1:256,806,476...256,813,678
Ensembl chr 1:256,806,472...256,813,711
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 ISO (PMID:25631937) RGD PMID:25631937 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
G Sash3 SAM and SH3 domain containing 3 IBA
ISO
PMID:21873635
MGI:3716944 (MGI:3607020|PMID:16227612)
RGD PMID:16227612, PMID:21873635 MGI:3607020, RGD:13792537 NCBI chr  X:134,979,637...134,994,351
Ensembl chr  X:134,979,646...134,994,349
JBrowse link
G Stx4 syntaxin 4 IEA
ISO
GO_REF:0000107
(PMID:24055037)
Ensembl
RGD
PMID:24055037 GO_REF:0000107 NCBI chr 1:199,287,384...199,295,606
Ensembl chr 1:199,287,710...199,294,979
JBrowse link
G Tlr9 toll-like receptor 9 ISO (PMID:23857366) RGD PMID:23857366 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171
JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 ISO (MGI:74350|PMID:7749983) RGD PMID:7749983 MGI:74350 NCBI chr 5:173,447,784...173,450,474
Ensembl chr 5:173,447,784...173,450,474
JBrowse link
G Tnfsf4 TNF superfamily member 4 ISO (MGI:74350|PMID:7749983) RGD PMID:7749983 MGI:74350 NCBI chr13:79,269,973...79,293,775
Ensembl chr13:79,269,973...79,293,778
JBrowse link
G Vamp3 vesicle-associated membrane protein 3 NOT ISO (PMID:24055037) RGD PMID:24055037 NCBI chr 5:168,126,157...168,136,628
Ensembl chr 5:168,126,157...168,136,666
JBrowse link
G Xbp1 X-box binding protein 1 ISO
ISS
(PMID:11460154)
(MGI:5605956|PMID:12612580)
GO_REF:0000024
RGD
UniProt
PMID:11460154, PMID:12612580 GO_REF:0000024, MGI:5605956 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
positive regulation of immunoglobulin production in mucosal tissue term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC688282 hypothetical protein LOC688282 ISO (MGI:6103709|PMID:28978694) RGD PMID:28978694 MGI:6103709 NCBI chr10:106,800,040...106,810,153
Ensembl chr10:106,800,142...106,809,239
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 IEA
ISO
GO_REF:0000107
(MGI:5009207|PMID:9973465)
Ensembl
RGD
PMID:9973465 GO_REF:0000107, MGI:5009207 NCBI chr13:83,199,402...83,202,845
Ensembl chr13:83,199,264...83,202,864
JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf4 TNF superfamily member 4 ISO (MGI:3763508|PMID:12496423) RGD PMID:12496423 MGI:3763508 NCBI chr13:79,269,973...79,293,775
Ensembl chr13:79,269,973...79,293,778
JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exosc3 exosome component 3 ISO (MGI:5009766|PMID:21255825) RGD PMID:21255825 MGI:5009766 NCBI chr 5:60,866,498...60,871,734
Ensembl chr 5:60,868,502...60,871,705
JBrowse link
G Exosc6 exosome component 6 ISO (MGI:5009766|PMID:21255825) RGD PMID:21255825 MGI:5009766 NCBI chr19:43,190,879...43,193,164
Ensembl chr19:43,191,390...43,192,208
JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific ISS
ISO
GO_REF:0000024
(MGI:6393148|PMID:31806351)
UniProt
RGD
PMID:31806351 GO_REF:0000024, MGI:6393148 NCBI chr 4:119,841,088...119,864,115
Ensembl chr 4:119,815,139...119,864,114
JBrowse link
G Kmt5b lysine methyltransferase 5B ISS
ISO
GO_REF:0000024
(MGI:6370097|PMID:28114273)
UniProt
RGD
PMID:28114273 GO_REF:0000024, MGI:6370097 NCBI chr 1:219,000,844...219,050,211
Ensembl chr 1:219,000,844...219,050,211
JBrowse link
G Kmt5c lysine methyltransferase 5C ISS
ISO
GO_REF:0000024
(MGI:6370097|PMID:28114273)
UniProt
RGD
PMID:28114273 GO_REF:0000024, MGI:6370097 NCBI chr 1:72,666,662...72,674,271
Ensembl chr 1:72,666,665...72,674,271
JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 5:164,943,183...164,956,255
Ensembl chr 5:164,950,917...164,956,255
JBrowse link
G Paxip1 PAX interacting protein 1 ISO (MGI:4821506|PMID:20671152) RGD PMID:20671152 MGI:4821506 NCBI chr 4:3,956,931...4,008,326
Ensembl chr 4:3,959,640...4,008,326
JBrowse link
G Rif1 replication timing regulatory factor 1 ISO (MGI:5468036|PMID:23306439), (MGI:5476381|PMID:23333305), (MGI:5490831|PMID:23333306) RGD PMID:23306439, PMID:23333305, PMID:23333306 MGI:5468036, MGI:5476381, MGI:5490831 NCBI chr 3:37,599,540...37,648,818
Ensembl chr 3:37,599,728...37,647,631
JBrowse link
G Shld1 shieldin complex subunit 1 ISO
IBA
(PMID:29656893)
PMID:21873635
RGD PMID:29656893, PMID:21873635 RGD:13792537 NCBI chr 3:125,318,682...125,396,705
Ensembl chr 3:125,320,680...125,396,821
JBrowse link
G Shld2 shieldin complex subunit 2 ISO (PMID:29656893) RGD PMID:29656893 NCBI chr16:10,570,307...10,661,528
Ensembl chr16:10,570,314...10,661,528
JBrowse link
G Tfrc transferrin receptor ISO
ISS
(PMID:26642240)
GO_REF:0000024
RGD
UniProt
PMID:26642240 GO_REF:0000024 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 ISO (PMID:23345425), (PMID:23760478)
(MGI:3041657|PMID:15077110), (MGI:3046005|PMID:15159415)
RGD PMID:15077110, PMID:15159415, PMID:23345425, PMID:23760478 MGI:3041657, MGI:3046005 NCBI chr 3:113,160,030...113,259,701
Ensembl chr 3:113,160,000...113,231,790
JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 IEA
ISO
GO_REF:0000107
(MGI:1342394|PMID:10430621)
Ensembl
RGD
PMID:10430621 GO_REF:0000107, MGI:1342394 NCBI chr 8:119,486,655...119,523,716
Ensembl chr 8:119,486,691...119,523,964
JBrowse link
G Msh2 mutS homolog 2 IEA
ISO
GO_REF:0000107
(MGI:1342394|PMID:10430621)
Ensembl
RGD
PMID:10430621 GO_REF:0000107, MGI:1342394 NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932
JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 ISO (MGI:5462481|PMID:23241889) RGD PMID:23241889 MGI:5462481 NCBI chr14:82,119,210...82,196,501
Ensembl chr14:82,119,210...82,171,480
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component ISO UniProtKB:Q9JK91 (MGI:1342394|PMID:10430621) RGD PMID:10430621 MGI:1342394 NCBI chr12:12,714,394...12,738,654
Ensembl chr12:12,714,394...12,738,641
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO
ISS
(PMID:14988498)
GO_REF:0000024
RGD
AgBase
PMID:14988498 GO_REF:0000024 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnfsf13 TNF superfamily member 13 ISO
IBA
(PMID:14988498)
MGI:3038886 (MGI:3037416|PMID:14988498)
PMID:21873635
RGD PMID:14988498, PMID:21873635 MGI:3037416, RGD:13792537 NCBI chr10:56,286,964...56,290,680
Ensembl chr10:56,286,887...56,289,952
JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcf1 cardiotrophin-like cytokine factor 1 ISO (MGI:3777853|PMID:12023368) RGD PMID:12023368 MGI:3777853 NCBI chr 1:219,468,866...219,472,445
Ensembl chr 1:219,468,675...219,472,654
JBrowse link
G Il4 interleukin 4 IBA
ISO
PMID:21873635
(MGI:3037416|PMID:14988498)
RGD PMID:14988498, PMID:21873635 MGI:3037416, RGD:13792537 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Stat6 signal transducer and activator of transcription 6 ISO MGI:107187 (MGI:1345885|PMID:10490661) RGD PMID:10490661 MGI:1345885 NCBI chr 7:70,946,228...70,963,542
Ensembl chr 7:70,946,228...70,964,484
JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 ISO MGI:4127920 (MGI:5763555|PMID:25404367) RGD PMID:25404367 MGI:5763555 NCBI chr10:67,427,042...67,475,825
Ensembl chr10:67,427,066...67,473,649
JBrowse link
G Cd28 Cd28 molecule IEA
ISO
GO_REF:0000107
MGI:1857150 (MGI:62368|PMID:7688139)
Ensembl
RGD
PMID:7688139 GO_REF:0000107, MGI:62368 NCBI chr 9:67,546,408...67,573,858
Ensembl chr 9:67,546,408...67,571,871
JBrowse link
G Cd40 CD40 molecule IBA
ISO
PMID:21873635
(MGI:2670820|PMID:12882831)
RGD PMID:12882831, PMID:21873635 MGI:2670820, RGD:13792537 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Ifng interferon gamma ISO (MGI:2670820|PMID:12882831) RGD PMID:12882831 MGI:2670820 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il2 interleukin 2 ISO MGI:1857191 (MGI:87443|PMID:1830926) RGD PMID:1830926 MGI:87443 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il4 interleukin 4 IBA
ISO
PMID:21873635
(MGI:2670820|PMID:12882831), (MGI:3037416|PMID:14988498)
RGD PMID:12882831, PMID:14988498, PMID:21873635 MGI:2670820, MGI:3037416, RGD:13792537 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Mlh1 mutL homolog 1 IEA
ISO
GO_REF:0000107
(MGI:1342394|PMID:10430621)
Ensembl
RGD
PMID:10430621 GO_REF:0000107, MGI:1342394 NCBI chr 8:119,486,655...119,523,716
Ensembl chr 8:119,486,691...119,523,964
JBrowse link
G Msh2 mutS homolog 2 IEA
ISO
GO_REF:0000107
(MGI:1342394|PMID:10430621)
Ensembl
RGD
PMID:10430621 GO_REF:0000107, MGI:1342394 NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932
JBrowse link
G Pagr1 Paxip1-associated glutamate-rich protein 1 ISO (MGI:5752090|PMID:26744420) RGD PMID:26744420 MGI:5752090 NCBI chr 1:198,448,790...198,451,078
Ensembl chr 1:198,449,040...198,450,688
JBrowse link
G Paxip1 PAX interacting protein 1 ISO (MGI:5752090|PMID:26744420) RGD PMID:26744420 MGI:5752090 NCBI chr 4:3,956,931...4,008,326
Ensembl chr 4:3,959,640...4,008,326
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component ISO UniProtKB:Q9JK91 (MGI:1342394|PMID:10430621) RGD PMID:10430621 MGI:1342394 NCBI chr12:12,714,394...12,738,654
Ensembl chr12:12,714,394...12,738,641
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C ISO MGI:2181288 (MGI:85031|PMID:9015183) RGD PMID:9015183 MGI:85031 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
G Tbx21 T-box transcription factor 21 ISO MGI:2180194 (MGI:2670820|PMID:12882831) RGD PMID:12882831 MGI:2670820 NCBI chr10:85,032,799...85,049,331
Ensembl chr10:85,032,799...85,049,331
JBrowse link
positive regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule ISO MGI:2447190 (MGI:3587138|PMID:16061696) RGD PMID:16061696 MGI:3587138 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd74 CD74 molecule ISS
ISO
IBA
GO_REF:0000024
(MGI:4943655|PMID:19413900)
PMID:21873635
BHF-UCL
RGD
PMID:19413900, PMID:21873635 GO_REF:0000024, MGI:4943655, RGD:13792537 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Gprc5b G protein-coupled receptor, class C, group 5, member B ISO (MGI:5545939|PMID:23169819) RGD PMID:23169819 MGI:5545939 NCBI chr 1:188,688,743...188,713,724
Ensembl chr 1:188,688,743...188,713,280
JBrowse link
G Rtn4 reticulon 4 ISS
ISO
GO_REF:0000024
(MGI:4366092|PMID:19805174)
UniProt
RGD
PMID:19805174 GO_REF:0000024, MGI:4366092 NCBI chr14:114,126,931...114,174,459
Ensembl chr14:114,126,943...114,174,458
JBrowse link
G Sema7a semaphorin 7A (John Milton Hagen blood group) IBA
ISO
PMID:21873635
(MGI:3710037|PMID:17377534)
RGD PMID:17377534, PMID:21873635 MGI:3710037, RGD:13792537 NCBI chr 8:62,723,788...62,746,530
Ensembl chr 8:62,723,788...62,745,868
JBrowse link
G Spon2 spondin 2 ISO MGI:3026870 (MGI:2686801|PMID:14691481) RGD PMID:14691481 MGI:2686801 NCBI chr14:82,815,158...82,824,529
Ensembl chr14:82,818,663...82,824,599
JBrowse link
G Tlr2 toll-like receptor 2 ISO MGI:2178675 (MGI:2178646|PMID:10549626) RGD PMID:10549626 MGI:2178646 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 IEA
ISO
GO_REF:0000107
MGI:1860885 (MGI:2178646|PMID:10549626)
Ensembl
RGD
PMID:10549626 GO_REF:0000107, MGI:2178646 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Wnt5a Wnt family member 5A IEA
ISO
GO_REF:0000107
(PMID:18174455)
Ensembl
RGD
PMID:18174455 GO_REF:0000107 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
positive regulation of mast cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc fragment of IgE receptor Ig ISO MGI:2384004 (MGI:3029067|PMID:14764707) RGD PMID:14764707 MGI:3029067 NCBI chr13:89,601,894...89,606,326
Ensembl chr13:89,601,896...89,606,326
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 ISS
ISO
GO_REF:0000024
(MGI:5586645|PMID:24586680)
UniProt
RGD
PMID:24586680 GO_REF:0000024, MGI:5586645 NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637
JBrowse link
positive regulation of myeloid dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx1 DEAD-box helicase 1 ISO (MGI:5050760|PMID:21703541) RGD PMID:21703541 MGI:5050760 NCBI chr 6:38,422,892...38,453,762
Ensembl chr 6:38,422,888...38,453,797
JBrowse link
G Ddx21 DExD-box helicase 21 ISO (MGI:5050760|PMID:21703541) RGD PMID:21703541 MGI:5050760 NCBI chr20:32,213,147...32,232,632
Ensembl chr20:32,213,148...32,232,632
JBrowse link
G Ddx58 DEXD/H-box helicase 58 ISO (MGI:5050760|PMID:21703541) RGD PMID:21703541 MGI:5050760 NCBI chr 5:56,486,584...56,536,898
Ensembl chr 5:56,500,734...56,536,772
JBrowse link
G Dhx36 DEAH-box helicase 36 ISO (MGI:5050760|PMID:21703541) RGD PMID:21703541 MGI:5050760 NCBI chr 2:152,785,844...152,824,549
Ensembl chr 2:152,785,844...152,824,547
JBrowse link
G Mavs mitochondrial antiviral signaling protein ISS
ISO
GO_REF:0000024
(MGI:5050760|PMID:21703541)
UniProt
RGD
PMID:21703541 GO_REF:0000024, MGI:5050760 NCBI chr 3:123,776,147...123,790,572
Ensembl chr 3:123,776,181...123,790,567
JBrowse link
G Ticam1 toll-like receptor adaptor molecule 1 ISO (MGI:5050760|PMID:21703541) RGD PMID:21703541 MGI:5050760 NCBI chr 9:10,780,185...10,790,280 JBrowse link
positive regulation of myeloid leukocyte cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mif macrophage migration inhibitory factor ISO (MGI:2156302|PMID:11756671) RGD PMID:11756671 MGI:2156302 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
positive regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07032888.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr18:87,415,531...87,415,884 JBrowse link
G Cd160 CD160 molecule ISO (PMID:17307798) RGD PMID:17307798 NCBI chr 2:198,933,681...198,965,380
Ensembl chr 2:198,935,133...198,942,732
JBrowse link
G Cd226 CD226 molecule IBA
ISO
PMID:21873635
MGI:4454325 (MGI:5569209|PMID:24658051)
RGD PMID:24658051, PMID:21873635 MGI:5569209, RGD:13792537 NCBI chr18:86,299,392...86,394,772
Ensembl chr18:86,299,463...86,394,765
JBrowse link
G Clnk cytokine-dependent hematopoietic cell linker ISO (MGI:3774350|PMID:16439675) RGD PMID:16439675 MGI:3774350 NCBI chr14:76,657,165...76,834,050
Ensembl chr14:76,657,311...76,833,161
JBrowse link
G Gimap5 GTPase, IMAP family member 5 IMP RGD PMID:15100275 RGD:2303778 NCBI chr 4:78,377,228...78,386,683
Ensembl chr 4:78,378,144...78,385,577
JBrowse link
G Il21 interleukin 21 ISO (MGI:3028812|PMID:14764669) RGD PMID:14764669 MGI:3028812 NCBI chr 2:123,965,021...123,972,356
Ensembl chr 2:123,965,021...123,972,356
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 ISO (PMID:27455421) RGD PMID:27455421 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 ISO (PMID:30134159) RGD PMID:30134159 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
positive regulation of prostaglandin secretion involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mif macrophage migration inhibitory factor ISO (MGI:2156302|PMID:11756671) RGD PMID:11756671 MGI:2156302 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
positive regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2 microglobulin ISO (PMID:24643698) RGD PMID:24643698 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Fzd5 frizzled class receptor 5 ISO
IEA
(PMID:16601243)
GO_REF:0000107
RGD
Ensembl
PMID:16601243 GO_REF:0000107 NCBI chr 9:71,443,784...71,445,541
Ensembl chr 9:71,443,588...71,445,739
JBrowse link
G LOC100364500 RT1 class I, locus CE11-like ISO (PMID:24643698) RGD PMID:24643698 NCBI chr20:2,704,153...2,707,111
Ensembl chr20:2,704,148...2,707,120
JBrowse link
G Malt1 MALT1 paracaspase ISO (PMID:15125833) RGD PMID:15125833 NCBI chr18:61,108,712...61,162,446
Ensembl chr18:61,109,069...61,162,445
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 ISO (PMID:15125833) RGD PMID:15125833 NCBI chr 5:47,183,142...47,244,424
Ensembl chr 5:47,186,558...47,244,416
JBrowse link
G Sash3 SAM and SH3 domain containing 3 ISO MGI:3716944 (MGI:3607020|PMID:16227612) RGD PMID:16227612 MGI:3607020 NCBI chr  X:134,979,637...134,994,351
Ensembl chr  X:134,979,646...134,994,349
JBrowse link
G Tnfsf4 TNF superfamily member 4 ISO (MGI:4942267|PMID:9670042), (MGI:4943387|PMID:18354165) RGD PMID:9670042, PMID:18354165 MGI:4942267, MGI:4943387 NCBI chr13:79,269,973...79,293,775
Ensembl chr13:79,269,973...79,293,778
JBrowse link
G Traf2 Tnf receptor-associated factor 2 ISO (PMID:15125833) RGD PMID:15125833 NCBI chr 3:2,746,061...2,770,690
Ensembl chr 3:2,746,075...2,770,620
JBrowse link
G Traf6 TNF receptor associated factor 6 ISO (PMID:15125833) RGD PMID:15125833 NCBI chr 3:91,252,829...91,271,607
Ensembl chr 3:91,252,829...91,271,607
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 ISO (MGI:85636|PMID:9029087) RGD PMID:9029087 MGI:85636 NCBI chr13:83,199,402...83,202,845
Ensembl chr13:83,199,264...83,202,864
JBrowse link
positive regulation of T-helper 1 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid5a AT-rich interaction domain 5A ISO (MGI:5887181|PMID:27671645) RGD PMID:27671645 MGI:5887181 NCBI chr 9:42,871,907...42,886,725
Ensembl chr 9:42,871,950...42,884,855
JBrowse link
G Il18 interleukin 18 ISS
ISO
IEA
GO_REF:0000024
(PMID:10653850)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:10653850 GO_REF:0000024, GO_REF:0000107 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il18r1 interleukin 18 receptor 1 ISO (PMID:10653850) RGD PMID:10653850 NCBI chr 9:47,184,404...47,217,403
Ensembl chr 9:47,185,443...47,219,175
JBrowse link
G Il1b interleukin 1 beta ISS
ISO
IEA
GO_REF:0000024
(PMID:10653850)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:10653850 GO_REF:0000024, GO_REF:0000107 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r1 interleukin 1 receptor type 1 ISS
ISO
IEA
GO_REF:0000024
(PMID:10653850)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:10653850 GO_REF:0000024, GO_REF:0000107 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 IEA
ISO
GO_REF:0000107
(MGI:5009207|PMID:9973465)
Ensembl
RGD
PMID:9973465 GO_REF:0000107, MGI:5009207 NCBI chr13:83,199,402...83,202,845
Ensembl chr13:83,199,264...83,202,864
JBrowse link
positive regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 Cd81 molecule ISS
ISO
IEA
GO_REF:0000024
(MGI:1926561|PMID:11046035)
(PMID:8766544)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:8766544, PMID:11046035 GO_REF:0000024, GO_REF:0000107, MGI:1926561 NCBI chr 1:216,237,663...216,253,460
Ensembl chr 1:216,237,697...216,253,311
JBrowse link
G Gata3 GATA binding protein 3 ISO (MGI:3046385|PMID:15087456) RGD PMID:15087456 MGI:3046385 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Il6 interleukin 6 ISO (MGI:5795829|PMID:11159963) RGD PMID:11159963 MGI:5795829 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 ISO (MGI:5689221|PMID:26098997) RGD PMID:26098997 MGI:5689221 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Prkcz protein kinase C, zeta ISS
ISO
GO_REF:0000024
(MGI:3584076|PMID:15987782)
UniProt
RGD
PMID:15987782 GO_REF:0000024, MGI:3584076 NCBI chr 5:172,658,071...172,769,492
Ensembl chr 5:172,658,748...172,769,421
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 IEA
ISO
ISS
GO_REF:0000107
(MGI:3844206|PMID:19047684)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:19047684 GO_REF:0000024, GO_REF:0000107, MGI:3844206 NCBI chr 6:45,655,947...45,669,083
Ensembl chr 6:45,655,954...45,669,148
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 IEA
ISO
GO_REF:0000107
(MGI:5009207|PMID:9973465)
Ensembl
RGD
PMID:9973465 GO_REF:0000107, MGI:5009207 NCBI chr13:83,199,402...83,202,845
Ensembl chr13:83,199,264...83,202,864
JBrowse link
regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg5 autophagy related 5 IEA
ISO
GO_REF:0000107
(MGI:5435097|PMID:22710871)
Ensembl
RGD
PMID:22710871 GO_REF:0000107, MGI:5435097 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B IBA
ISO
PMID:21873635
UniProtKB:Q9Z0D9 (MGI:5888814|PMID:28052249)
RGD PMID:28052249, PMID:21873635 MGI:5888814, RGD:13792537 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
G Tril TLR4 interactor with leucine-rich repeats ISO
IBA
(PMID:19710467)
PMID:21873635
RGD PMID:19710467, PMID:21873635 RGD:13792537 NCBI chr 4:83,967,695...83,972,540
Ensembl chr 4:83,967,696...83,972,540
JBrowse link
regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr2 toll-like receptor 2 ISO (MGI:3828894|PMID:19047410) RGD PMID:19047410 MGI:3828894 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr3 toll-like receptor 3 ISO (MGI:3828894|PMID:19047410) RGD PMID:19047410 MGI:3828894 NCBI chr16:50,016,466...50,031,011
Ensembl chr16:50,016,857...50,031,214
JBrowse link
G Tlr4 toll-like receptor 4 IEA
ISO
GO_REF:0000107
(MGI:3828894|PMID:19047410)
Ensembl
RGD
PMID:19047410 GO_REF:0000107, MGI:3828894 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tlr9 toll-like receptor 9 ISO (MGI:3828894|PMID:19047410) RGD PMID:19047410 MGI:3828894 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171
JBrowse link
regulation of immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40 CD40 molecule IBA
ISO
PMID:21873635
(MGI:2680840|PMID:12958312)
RGD PMID:12958312, PMID:21873635 MGI:2680840, RGD:13792537 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd40lg CD40 ligand IEA
ISO
GO_REF:0000107
(MGI:2680840|PMID:12958312)
Ensembl
RGD
PMID:12958312 GO_REF:0000107, MGI:2680840 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cgas cyclic GMP-AMP synthase ISO MGI:1328317 (MGI:5699498|PMID:26371324) RGD PMID:26371324 MGI:5699498 NCBI chr 8:85,789,515...85,804,008
Ensembl chr 8:85,789,763...85,803,433
JBrowse link
G Foxp3 forkhead box P3 ISO MGI:3696705 (MGI:3695768|PMID:16275384) RGD PMID:16275384 MGI:3695768 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Pkn1 protein kinase N1 ISO MGI:5475202 (MGI:5467878|PMID:23223530) RGD PMID:23223530 MGI:5467878 NCBI chr19:24,803,524...24,832,305
Ensembl chr19:24,803,524...24,831,500
JBrowse link
G Tnf tumor necrosis factor ISO (MGI:2680840|PMID:12958312) RGD PMID:12958312 MGI:2680840 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Traf2 Tnf receptor-associated factor 2 ISO (MGI:2680840|PMID:12958312) RGD PMID:12958312 MGI:2680840 NCBI chr 3:2,746,061...2,770,690
Ensembl chr 3:2,746,075...2,770,620
JBrowse link
G Traf6 TNF receptor associated factor 6 ISO (MGI:2680840|PMID:12958312) RGD PMID:12958312 MGI:2680840 NCBI chr 3:91,252,829...91,271,607
Ensembl chr 3:91,252,829...91,271,607
JBrowse link
G Trex1 three prime repair exonuclease 1 ISO MGI:2442261 (MGI:5699498|PMID:26371324), (MGI:5787754|PMID:26320659) RGD PMID:26320659, PMID:26371324 MGI:5699498, MGI:5787754 NCBI chr 8:117,796,127...117,797,427
Ensembl chr 8:117,796,128...117,797,427
JBrowse link
regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplf aprataxin and PNKP like factor ISO MGI:4128102 (MGI:4887518|PMID:21211721) RGD PMID:21211721 MGI:4887518 NCBI chr 4:119,514,822...119,568,764
Ensembl chr 4:119,514,840...119,568,736
JBrowse link
G Mir181b1 microRNA 181b-1 ISO (MGI:3817382|PMID:18762567) RGD PMID:18762567 MGI:3817382 NCBI chr13:54,952,903...54,953,012
Ensembl chr13:54,952,903...54,953,012
JBrowse link
G Mir181b2 microRNA 181b-2 ISO (MGI:3817382|PMID:18762567) RGD PMID:18762567 MGI:3817382 NCBI chr 3:23,151,455...23,151,542
Ensembl chr 3:23,151,455...23,151,542
JBrowse link
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor ISO (MGI:5004983|PMID:21518874) RGD PMID:21518874 MGI:5004983 NCBI chr10:65,470,470...65,507,581
Ensembl chr10:65,470,471...65,507,581
JBrowse link
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 ISO MGI:3696705 (MGI:3695768|PMID:16275384) RGD PMID:16275384 MGI:3695768 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Il27ra interleukin 27 receptor subunit alpha ISO MGI:3525439 (MGI:1926579|PMID:11057672) RGD PMID:11057672 MGI:1926579 NCBI chr19:25,151,835...25,163,995
Ensembl chr19:25,149,897...25,164,086
JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 ISO MGI:3695433 (MGI:3694584|PMID:17137798) RGD PMID:17137798 MGI:3694584 NCBI chr18:31,574,759...31,625,286
Ensembl chr18:31,574,821...31,625,274
JBrowse link
G Slc15a4 solute carrier family 15 member 4 ISS
ISO
IEA
GO_REF:0000024
(MGI:5649169|PMID:25310967)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:25310967 GO_REF:0000024, GO_REF:0000107, MGI:5649169 NCBI chr12:32,753,824...32,773,277
Ensembl chr12:32,753,824...32,773,277
JBrowse link
regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl20 C-C motif chemokine ligand 20 NOT ISO (MGI:3820359|PMID:19050256) RGD PMID:19050256 MGI:3820359 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISS
ISO
GO_REF:0000024
(MGI:5926947|PMID:28507030)
UniProt
RGD
PMID:28507030 GO_REF:0000024, MGI:5926947
G Tnfrsf1b TNF receptor superfamily member 1B IBA
ISO
PMID:21873635
(MGI:5888814|PMID:28052249)
RGD PMID:28052249, PMID:21873635 MGI:5888814, RGD:13792537 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:20656926)
Ensembl
UniProt
RGD
PMID:20656926 GO_REF:0000024, GO_REF:0000107 NCBI chr 1:101,293,300...101,323,484
Ensembl chr 1:101,293,409...101,323,960
JBrowse link
somatic diversification of immunoglobulins term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase ISO (PMID:18722174) RGD PMID:18722174 NCBI chr 4:155,359,909...155,371,104
Ensembl chr 4:155,359,921...155,369,671
JBrowse link
G Ctnnbl1 catenin, beta like 1 ISO (PMID:18722174) RGD PMID:18722174 NCBI chr 3:154,212,245...154,373,170
Ensembl chr 3:154,212,202...154,373,169
JBrowse link
G Polb DNA polymerase beta ISO MGI:5427084 (MGI:5553198|PMID:24388753) RGD PMID:24388753 MGI:5553198 NCBI chr16:74,237,001...74,260,272
Ensembl chr16:74,237,001...74,260,271
JBrowse link
somatic hypermutation of immunoglobulin genes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase ISO (PMID:21518874) RGD PMID:21518874 NCBI chr 4:155,359,909...155,371,104
Ensembl chr 4:155,359,921...155,369,671
JBrowse link
G Exo1 exonuclease 1 ISO MGI:2653925 (MGI:3028407|PMID:14716311) RGD PMID:14716311 MGI:3028407 NCBI chr13:93,936,989...93,962,749
Ensembl chr13:93,939,022...93,960,342
JBrowse link
G Mcm3ap minichromosome maintenance complex component 3 associated protein ISO (PMID:23652018) RGD PMID:23652018 NCBI chr20:12,879,304...12,917,069
Ensembl chr20:12,879,278...12,917,039
JBrowse link
G Mlh1 mutL homolog 1 IEA
ISO
IBA
GO_REF:0000107
MGI:1857946 (MGI:1332749|PMID:10092760), (MGI:3691360|PMID:10429667)
PMID:21873635
Ensembl
RGD
PMID:10092760, PMID:10429667, PMID:21873635 GO_REF:0000107, MGI:1332749, MGI:3691360, RGD:13792537 NCBI chr 8:119,486,655...119,523,716
Ensembl chr 8:119,486,691...119,523,964
JBrowse link
G Msh2 mutS homolog 2 NOT IEA
ISO
GO_REF:0000107
MGI:109352|MGI:1857940|MGI:1858055|MGI:2680817 (MGI:1275866|PMID:9697842), (MGI:1275867|PMID:9697843), (MGI:2679186|PMID:14568978), (MGI:3513244|PMID:15494304), (MGI:3641481|PMID:9607916)
MGI:1858055 (MGI:1261398|PMID:9607915)
Ensembl
RGD
PMID:9607915, PMID:9607916, PMID:9697842, PMID:9697843, PMID:14568978, PMID:15494304 GO_REF:0000107, MGI:1261398, MGI:1275866, MGI:1275867, MGI:2679186, MGI:3513244, MGI:3641481 NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932
JBrowse link
G Msh3 mutS homolog 3 NOT ISO MGI:1858056 (MGI:1353126|PMID:10662804) RGD PMID:10662804 MGI:1353126 NCBI chr 2:21,790,048...21,931,791
Ensembl chr 2:21,790,044...21,931,720
JBrowse link
G Msh6 mutS homolog 6 IBA
ISO
PMID:21873635
MGI:1858014|MGI:3653701 (MGI:1353126|PMID:10662804), (MGI:3046392|PMID:15238604), (MGI:3641510|PMID:16618598), (MGI:3723381|PMID:17015724)
RGD PMID:10662804, PMID:15238604, PMID:16618598, PMID:17015724, PMID:21873635 MGI:1353126, MGI:3046392, MGI:3641510, MGI:3723381, RGD:13792537 NCBI chr 6:11,644,565...11,662,389
Ensembl chr 6:11,644,578...11,662,499
JBrowse link
G Nuggc nuclear GTPase, germinal center associated ISO MGI:5449552 (MGI:5448793|PMID:22833677) RGD PMID:22833677 MGI:5448793 NCBI chr15:49,011,951...49,055,246
Ensembl chr15:49,010,492...49,055,237
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component IBA
ISO
PMID:21873635
MGI:1857947 (MGI:1261707|PMID:9618520), (MGI:3691360|PMID:10429667)
RGD PMID:9618520, PMID:10429667, PMID:21873635 MGI:1261707, MGI:3691360, RGD:13792537 NCBI chr12:12,714,394...12,738,654
Ensembl chr12:12,714,394...12,738,641
JBrowse link
G Polb DNA polymerase beta ISO MGI:5427084 (MGI:5553198|PMID:24388753) RGD PMID:24388753 MGI:5553198 NCBI chr16:74,237,001...74,260,272
Ensembl chr16:74,237,001...74,260,271
JBrowse link
G Polm DNA polymerase mu ISO MGI:2179233 (MGI:3576407|PMID:15789338) RGD PMID:15789338 MGI:3576407 NCBI chr14:86,069,378...86,079,327
Ensembl chr14:86,069,016...86,078,954
JBrowse link
G Polq DNA polymerase theta ISO (MGI:3603978|PMID:16172387), (MGI:3609287|PMID:16222339), (MGI:3692678|PMID:16890500) RGD PMID:16172387, PMID:16222339, PMID:16890500 MGI:3603978, MGI:3609287, MGI:3692678 NCBI chr11:66,585,860...66,695,369
Ensembl chr11:66,585,881...66,695,353
JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 ISO (MGI:6157199|PMID:29669924) RGD PMID:29669924 MGI:6157199 NCBI chr 3:153,210,829...153,250,705
Ensembl chr 3:153,210,829...153,250,641
JBrowse link
G Ung uracil-DNA glycosylase ISO MGI:101816|MGI:2182610 (MGI:3513244|PMID:15494304), (MGI:3723381|PMID:17015724) RGD PMID:15494304, PMID:17015724 MGI:3513244, MGI:3723381 NCBI chr12:48,246,593...48,255,547
Ensembl chr12:48,246,569...48,254,822
JBrowse link
somatic recombination of immunoglobulin gene segments term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 ISO MGI:1857946 (MGI:3722579|PMID:11828012) RGD PMID:11828012 MGI:3722579 NCBI chr 8:119,486,655...119,523,716
Ensembl chr 8:119,486,691...119,523,964
JBrowse link
G Msh2 mutS homolog 2 ISO MGI:109352|MGI:1857940|MGI:2151801|MGI:2680817 (MGI:2679186|PMID:14568978), (MGI:3513244|PMID:15494304), (MGI:3581477|PMID:15955838), (MGI:3582380|PMID:14563316), (MGI:3722579|PMID:11828012) RGD PMID:11828012, PMID:14563316, PMID:14568978, PMID:15494304, PMID:15955838 MGI:2679186, MGI:3513244, MGI:3581477, MGI:3582380, MGI:3722579 NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932
JBrowse link
G Msh3 mutS homolog 3 IBA
ISO
PMID:21873635
MGI:1858056 (MGI:3046392|PMID:15238604)
RGD PMID:15238604, PMID:21873635 MGI:3046392, RGD:13792537 NCBI chr 2:21,790,048...21,931,791
Ensembl chr 2:21,790,044...21,931,720
JBrowse link
G Msh6 mutS homolog 6 IBA
ISO
PMID:21873635
MGI:1858014 (MGI:3046392|PMID:15238604)
RGD PMID:15238604, PMID:21873635 MGI:3046392, RGD:13792537 NCBI chr 6:11,644,565...11,662,389
Ensembl chr 6:11,644,578...11,662,499
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component ISO MGI:1857947 (MGI:3722579|PMID:11828012) RGD PMID:11828012 MGI:3722579 NCBI chr12:12,714,394...12,738,654
Ensembl chr12:12,714,394...12,738,641
JBrowse link
G Ung uracil-DNA glycosylase ISO MGI:101816|MGI:2182610 (MGI:3513244|PMID:15494304) RGD PMID:15494304 MGI:3513244 NCBI chr12:48,246,593...48,255,547
Ensembl chr12:48,246,569...48,254,822
JBrowse link
somatic recombination of immunoglobulin genes involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 ISO MGI:101816 (MGI:2662086|PMID:12743174) RGD PMID:12743174 MGI:2662086 NCBI chr 8:119,486,655...119,523,716
Ensembl chr 8:119,486,691...119,523,964
JBrowse link
G Msh2 mutS homolog 2 IBA
ISO
PMID:21873635
MGI:101938 (MGI:2662086|PMID:12743174)
RGD PMID:12743174, PMID:21873635 MGI:2662086, RGD:13792537 NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    immune system process 2840
      production of molecular mediator of immune response 195
        antimicrobial peptide production + 9
        cytokine production involved in immune response + 93
        granulysin production 0
        granzyme A production + 1
        granzyme B production + 3
        immunoglobulin production + 106
        negative regulation of production of molecular mediator of immune response + 39
        perforin production 0
        positive regulation of production of molecular mediator of immune response + 115
        prostaglandin secretion involved in immune response + 1
        regulation of production of molecular mediator of immune response + 165
Path 2
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      organic substance metabolic process 11643
        macromolecule metabolic process 10077
          gene expression 6300
            production of molecular mediator of immune response 195
              antimicrobial peptide production + 9
              cytokine production involved in immune response + 93
              granulysin production 0
              granzyme A production + 1
              granzyme B production + 3
              immunoglobulin production + 106
              negative regulation of production of molecular mediator of immune response + 39
              perforin production 0
              positive regulation of production of molecular mediator of immune response + 115
              prostaglandin secretion involved in immune response + 1
              regulation of production of molecular mediator of immune response + 165
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.